BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 437 hits with Last Name = 'min' and Initial = 'yk'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515773
PNG
(US11053225, Compound 23)
Show SMILES Cn1cc(cn1)-c1cnc(NC23CC4CC(CC(C4)C2)C3)nc1NC1CCCCC1 |TLB:20:11:18:14.15.16,THB:10:11:18:14.15.16,20:15:18:11.19.12,19:11:14:18.17.16,19:17:14:11.20.12|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515838
PNG
(US11053225, Compound 139)
Show SMILES Cn1cc(cn1)-c1cnc(Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)nc1Nc1ccc2CCN(Cc2c1)C(=O)C(F)(F)F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.00600n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515828
PNG
(US11053225, Compound 129 | US11053225, Compound 19...)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2Cl)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0100n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515810
PNG
(US11053225, Compound 201)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc(cc1)C1CCNCC1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0120n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515870
PNG
(US11053225, Compound 172)
Show SMILES CCCn1cc(cn1)-c1cnc(Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0120n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515869
PNG
(US11053225, Compound 171)
Show SMILES CCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0120n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515820
PNG
(US11053225, Compound 101 | US11053225, Compound 19...)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0120n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515814
PNG
(US11053225, Compound 84)
Show SMILES Cn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0410n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515817
PNG
(US11053225, Compound 89)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0410n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515826
PNG
(US11053225, Compound 127)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0520n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515794
PNG
(US11053225, Compound 75)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1NC1CCNCC1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0600n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515836
PNG
(US11053225, Compound 137)
Show SMILES Cn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0970n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515865
PNG
(US11053225, Compound 167)
Show SMILES CC(C)n1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515786
PNG
(US11053225, Compound 69)
Show SMILES COc1ccc(cc1OC)-c1cnc(Nc2cccc(Cl)c2)nc1NC1CCN(CC1)C(=O)C(F)(F)F
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.120n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515871
PNG
(US11053225, Compound 173)
Show SMILES CCCn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.130n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515846
PNG
(US11053225, Compound 147)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(F)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.130n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515847
PNG
(US11053225, Compound 148)
Show SMILES COc1cc(Nc2ncc(-c3cnn(CCO)c3)c(Nc3ccc4CCNCc4c3)n2)cc(c1)C(F)(F)F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.130n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515860
PNG
(US11053225, Compound 162)
Show SMILES CC(C)n1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.140n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515812
PNG
(US11053225, Compound 205)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc(cc1)C1CCNCC1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.140n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515879
PNG
(US11053225, Compound 181)
Show SMILES CC(C)Cn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.160n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515830
PNG
(US11053225, Compound 131)
Show SMILES Fc1cc(F)cc(Nc2ncc(-c3cnn(c3)C3CCNCC3)c(Nc3ccc4CCNCc4c3)n2)c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.160n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515858
PNG
(US11053225, Compound 160)
Show SMILES CC(C)n1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.160n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515867
PNG
(US11053225, Compound 169)
Show SMILES CC(C)n1cc(cn1)-c1cnc(Nc2cccc(C)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.170n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515877
PNG
(US11053225, Compound 179)
Show SMILES CC(C)Cn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.170n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515857
PNG
(US11053225, Compound 159)
Show SMILES Cc1ccc(F)cc1Nc1ncc(-c2cnn(C)c2)c(Nc2ccc3CCNCc3c2)n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.170n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515799
PNG
(US11053225, Compound 103)
Show SMILES N[C@H]1CC[C@H](CC1)Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cnn(CCO)c1 |r,wU:4.7,1.0,(5.92,3.85,;4.58,3.08,;4.58,1.54,;3.25,.77,;1.92,1.54,;1.92,3.08,;3.25,3.85,;.58,.77,;.58,-.77,;1.92,-1.54,;1.92,-3.08,;3.25,-3.85,;4.58,-3.08,;5.92,-3.85,;7.25,-3.08,;8.59,-3.85,;7.25,-1.54,;5.92,-.77,;5.92,.77,;4.58,-1.54,;.58,-3.85,;-.75,-3.08,;-.75,-1.54,;-2.08,-.77,;-2.25,.76,;-3.75,1.08,;-4.52,-.25,;-6.01,-.65,;-7.1,.44,;-8.59,.04,;-3.49,-1.4,)|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.190n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515831
PNG
(US11053225, Compound 132)
Show SMILES Clc1cc(Cl)cc(Nc2ncc(-c3cnn(c3)C3CCNCC3)c(Nc3ccc4CCNCc4c3)n2)c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.200n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM515783
PNG
(US11053225, Compound 65)
Show SMILES COc1ccccc1Nc1ncc(c(NC2CCN(CC2)C(=O)C(F)(F)F)n1)-c1ccc(OC)c(OC)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.210n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515861
PNG
(US11053225, Compound 163)
Show SMILES CC(C)n1cc(cn1)-c1cnc(Nc2cc(F)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.230n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515880
PNG
(US11053225, Compound 182)
Show SMILES CC(C)Cn1cc(cn1)-c1cnc(Nc2cc(F)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.270n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515876
PNG
(US11053225, Compound 178)
Show SMILES CCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.270n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515803
PNG
(US11053225, Compound 110)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1N[C@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wU:24.26,wD:27.33,(3.74,-9.89,;4.65,-8.64,;4.02,-7.23,;4.92,-5.99,;4.45,-4.52,;5.69,-3.62,;6.94,-4.52,;6.46,-5.99,;5.69,-2.08,;7.03,-1.31,;7.03,.23,;5.69,1,;5.69,2.54,;4.36,3.31,;3.03,2.54,;1.69,3.31,;.36,2.54,;1.69,4.85,;3.03,5.62,;3.03,7.16,;4.36,4.85,;4.36,.23,;4.36,-1.31,;3.03,-2.08,;1.69,-1.31,;.36,-2.08,;-.97,-1.31,;-.97,.23,;.36,1,;1.69,.23,;-2.31,1,;-2.31,2.54,;-.97,3.31,;-3.64,3.31,;-4.97,4.08,;-2.87,4.65,;-4.41,1.98,)|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.280n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515844
PNG
(US11053225, Compound 145)
Show SMILES Cn1cc(cn1)-c1cnc(Nc2cc(F)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.300n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515873
PNG
(US11053225, Compound 175)
Show SMILES CCCn1cc(cn1)-c1cnc(Nc2cc(F)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.320n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515864
PNG
(US11053225, Compound 166)
Show SMILES CC(C)n1cc(cn1)-c1cnc(Nc2cc(C)cc(C)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.340n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515854
PNG
(US11053225, Compound 156)
Show SMILES Cc1ccccc1Nc1ncc(-c2cnn(C)c2)c(Nc2ccc3CCNCc3c2)n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.340n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515821
PNG
(US11053225, Compound 102)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.360n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515805
PNG
(US11053225, Compound 113)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cnn(CCO)c1 |r,wU:1.0,wD:4.7,(5.88,3.85,;4.55,3.08,;4.55,1.54,;3.22,.77,;1.88,1.54,;1.88,3.08,;3.22,3.85,;.55,.77,;.55,-.77,;1.88,-1.54,;1.88,-3.08,;3.22,-3.85,;4.55,-3.08,;5.88,-3.85,;7.22,-3.08,;8.55,-3.85,;7.22,-1.54,;5.88,-.77,;5.88,.77,;4.55,-1.54,;.55,-3.85,;-.78,-3.08,;-.78,-1.54,;-2.12,-.77,;-2.12,.77,;-3.58,1.25,;-4.49,,;-5.98,-.4,;-7.06,.69,;-8.55,.29,;-3.58,-1.25,)|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.370n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515821
PNG
(US11053225, Compound 102)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.420n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515804
PNG
(US11053225, Compound 111)
Show SMILES N[C@H]1CC[C@H](CC1)Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cnn(c1)C1CCNCC1 |r,wU:4.7,1.0,(6.08,3.85,;4.75,3.08,;4.75,1.54,;3.42,.77,;2.08,1.54,;2.08,3.08,;3.42,3.85,;.75,.77,;.75,-.77,;2.08,-1.54,;2.08,-3.08,;3.42,-3.85,;4.75,-3.08,;6.08,-3.85,;7.42,-3.08,;8.75,-3.85,;7.42,-1.54,;6.08,-.77,;6.08,.77,;4.75,-1.54,;.75,-3.85,;-.58,-3.08,;-.58,-1.54,;-1.92,-.77,;-1.92,.77,;-3.38,1.25,;-4.29,,;-3.38,-1.25,;-5.78,-.4,;-6.86,.69,;-8.35,.29,;-8.75,-1.2,;-7.66,-2.28,;-6.17,-1.89,)|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.480n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515890
PNG
(US11053225, Compound 194)
Show SMILES Cc1cc(C)cc(Nc2ncc(-c3cnn(CCO)c3)c(Nc3ccc4CCNCc4c3)n2)c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.580n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515820
PNG
(US11053225, Compound 101 | US11053225, Compound 19...)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.600n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515836
PNG
(US11053225, Compound 137)
Show SMILES Cn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.780n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515783
PNG
(US11053225, Compound 65)
Show SMILES COc1ccccc1Nc1ncc(c(NC2CCN(CC2)C(=O)C(F)(F)F)n1)-c1ccc(OC)c(OC)c1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.820n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515798
PNG
(US11053225, Compound 100)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wD:23.25,26.32,(1.73,-9.37,;.83,-8.12,;1.45,-6.72,;.55,-5.47,;1.02,-4.01,;-.22,-3.1,;-1.47,-4.01,;-.99,-5.47,;-.22,-1.56,;-1.56,-.79,;-1.56,.75,;-.22,1.52,;-.22,3.06,;-1.56,3.83,;-1.56,5.37,;-2.89,6.14,;-4.22,5.37,;-4.22,3.83,;-5.56,3.06,;-2.89,3.06,;1.11,.75,;1.11,-.79,;2.45,-1.56,;3.78,-.79,;3.78,.75,;5.11,1.52,;6.45,.75,;6.45,-.79,;5.11,-1.56,;7.78,1.52,;9.11,.75,;9.11,-.79,;10.45,1.52,;11.78,2.29,;11.22,.19,;9.68,2.85,)|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.900n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515806
PNG
(US11053225, Compound 115)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(F)cc(F)c2)nc1NC1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wD:27.33,(3.3,-10.38,;4.21,-9.13,;3.58,-7.72,;4.49,-6.48,;4.01,-5.01,;5.26,-4.11,;6.5,-5.01,;6.03,-6.48,;5.26,-2.57,;6.59,-1.8,;6.59,-.26,;5.26,.51,;5.26,2.05,;3.92,2.82,;2.59,2.05,;1.26,2.82,;-.08,2.05,;1.26,4.36,;2.59,5.13,;2.59,6.67,;3.92,4.36,;3.92,-.26,;3.92,-1.8,;2.59,-2.57,;1.26,-1.8,;-.08,-2.57,;-1.41,-1.8,;-1.41,-.26,;-.08,.51,;1.26,-.26,;-2.74,.51,;-2.74,2.05,;-1.41,2.82,;-4.08,2.82,;-5.41,3.59,;-3.31,4.16,;-4.85,1.49,)|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.900n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515798
PNG
(US11053225, Compound 100)
Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wD:23.25,26.32,(1.73,-9.37,;.83,-8.12,;1.45,-6.72,;.55,-5.47,;1.02,-4.01,;-.22,-3.1,;-1.47,-4.01,;-.99,-5.47,;-.22,-1.56,;-1.56,-.79,;-1.56,.75,;-.22,1.52,;-.22,3.06,;-1.56,3.83,;-1.56,5.37,;-2.89,6.14,;-4.22,5.37,;-4.22,3.83,;-5.56,3.06,;-2.89,3.06,;1.11,.75,;1.11,-.79,;2.45,-1.56,;3.78,-.79,;3.78,.75,;5.11,1.52,;6.45,.75,;6.45,-.79,;5.11,-1.56,;7.78,1.52,;9.11,.75,;9.11,-.79,;10.45,1.52,;11.78,2.29,;11.22,.19,;9.68,2.85,)|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.910n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM515807
PNG
(US11053225, Compound 117)
Show SMILES N[C@H]1CCC(CC1)Nc1nc(Nc2cc(F)cc(F)c2)ncc1-c1cnn(CCO)c1 |r,wU:1.0,(5.88,3.85,;4.55,3.08,;4.55,1.54,;3.22,.77,;1.88,1.54,;1.88,3.08,;3.22,3.85,;.55,.77,;.55,-.77,;1.88,-1.54,;1.88,-3.08,;3.22,-3.85,;4.55,-3.08,;5.88,-3.85,;7.22,-3.08,;8.55,-3.85,;7.22,-1.54,;5.88,-.77,;5.88,.77,;4.55,-1.54,;.55,-3.85,;-.78,-3.08,;-.78,-1.54,;-2.12,-.77,;-2.12,.77,;-3.58,1.25,;-4.49,,;-5.98,-.4,;-7.06,.69,;-8.55,.29,;-3.58,-1.25,)|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515848
PNG
(US11053225, Compound 149)
Show SMILES Cn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))
BDBM515884
PNG
(US11053225, Compound 186)
Show SMILES CC(C)Cn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2CCNCc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/an/an/a


TBA

Assay Description
For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2DST
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 437 total )  |  Next  |  Last  >>
Jump to: