Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298243 ((2E,6E)-8-(2-diazo-3,3,3-trifluoropropanoyloxy)-3,...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298245 (4-Benzoylbenzylphosphonic((2E,6E)-3,7,11-trimethyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298242 ((E)-4-(3-benzoylbenzyloxy)-3-methylbut-2-enyl diph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298243 ((2E,6E)-8-(2-diazo-3,3,3-trifluoropropanoyloxy)-3,...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298245 (4-Benzoylbenzylphosphonic((2E,6E)-3,7,11-trimethyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298242 ((E)-4-(3-benzoylbenzyloxy)-3-methylbut-2-enyl diph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae) | BDBM50298244 (3-Benzoylbenzylphosphonic((2E,6E)-3,7,11-trimethyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae protein farnesyltransferase assessed as farnsylation of N-dansyl-GCVIA | Bioorg Med Chem 17: 4797-805 (2009) Article DOI: 10.1016/j.bmc.2009.04.034 BindingDB Entry DOI: 10.7270/Q2HT2PCH | |||||||||||
More data for this Ligand-Target Pair |