Compile Data Set for Download or QSAR

Found 15 hits with Last Name = 'amano' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor B (RAT)	BDBM50287290 (CHEMBL34866 | KRH-594 | Potassium; 2-[5-ethyl-3-[2...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)C2=C(CCC2)C([O-])=O)s1 |w:24.27,t:30| Show InChI InChI=1S/C25H23N7O3S/c1-2-21-29-32(25(36-21)26-23(33)19-8-5-9-20(19)24(34)35)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-30-31-28-22/h3-4,6-7,10-13H,2,5,8-9,14H2,1H3,(H,34,35)(H,27,28,30,31)/p-1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50287294 (2-[5-Ethyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)C2=C(CCC2)C(O)=O)s1 |w:24.27,t:30| Show InChI InChI=1S/C25H23N7O3S/c1-2-21-29-32(25(36-21)26-23(33)19-8-5-9-20(19)24(34)35)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-30-31-28-22/h3-4,6-7,10-13H,2,5,8-9,14H2,1H3,(H,34,35)(H,27,28,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50287291 (CHEMBL35381 | N-[5-Ethyl-3-[2'-(1H-tetrazol-5-yl)-...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)c2ccccc2C(O)=O)s1 |w:24.27| Show InChI InChI=1S/C26H21N7O3S/c1-2-22-30-33(26(37-22)27-24(34)20-9-5-6-10-21(20)25(35)36)15-16-11-13-17(14-12-16)18-7-3-4-8-19(18)23-28-31-32-29-23/h3-14H,2,15H2,1H3,(H,35,36)(H,28,29,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50287289 (2-Chloro-N-[5-ethyl-3-[2'-(1H-tetrazol-5-yl)-biphe...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)c2ccccc2Cl)s1 |w:24.27| Show InChI InChI=1S/C25H20ClN7OS/c1-2-22-30-33(25(35-22)27-24(34)20-9-5-6-10-21(20)26)15-16-11-13-17(14-12-16)18-7-3-4-8-19(18)23-28-31-32-29-23/h3-14H,2,15H2,1H3,(H,28,29,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50287292 (CHEMBL34190 | Cyclopropanecarboxylic acid [5-ethyl...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)C2CC2)s1 |w:24.27| Show InChI InChI=1S/C22H21N7OS/c1-2-19-26-29(22(31-19)23-21(30)16-11-12-16)13-14-7-9-15(10-8-14)17-5-3-4-6-18(17)20-24-27-28-25-20/h3-10,16H,2,11-13H2,1H3,(H,24,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50287295 (CHEMBL35475 | N-[5-Ethyl-3-[2'-(1H-tetrazol-5-yl)-...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(C)=O)s1 |w:24.27| Show InChI InChI=1S/C20H19N7OS/c1-3-18-24-27(20(29-18)21-13(2)28)12-14-8-10-15(11-9-14)16-6-4-5-7-17(16)19-22-25-26-23-19/h4-11H,3,12H2,1-2H3,(H,22,23,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50406795 (Cozaar | LOSARTAN POTASSIUM) Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1 Show InChI InChI=1S/C22H22ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3/q-1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50287293 (CHEMBL286537 | N-[5-Ethyl-3-[2'-(1H-tetrazol-5-yl)...) Show SMILES CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)c2ccccc2)s1 |w:24.27| Show InChI InChI=1S/C25H21N7OS/c1-2-22-29-32(25(34-22)26-24(33)19-8-4-3-5-9-19)16-17-12-14-18(15-13-17)20-10-6-7-11-21(20)23-27-30-31-28-23/h3-15H,2,16H2,1H3,(H,27,28,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)				Bioorg Med Chem Lett 6: 1469-1474 (1996) Article DOI: 10.1016/S0960-894X(96)00250-8 BindingDB Entry DOI: 10.7270/Q2SN08XQ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50131703 (CHEMBL3633520) Show SMILES CCNC1CN(C1)c1c(F)cc2c(c1C)n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F Show InChI InChI=1S/C21H20F3N5O3/c1-3-26-10-6-28(7-10)17-9(2)16-11(4-13(17)22)18(30)12(21(31)32)8-29(16)20-15(24)5-14(23)19(25)27-20/h4-5,8,10,26H,3,6-7H2,1-2H3,(H2,25,27)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50131705 (CHEMBL3633518) Show SMILES Cc1c(N2CC(N)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F Show InChI InChI=1S/C19H16F3N5O3/c1-7-14-9(2-11(20)15(7)26-4-8(23)5-26)16(28)10(19(29)30)6-27(14)18-13(22)3-12(21)17(24)25-18/h2-3,6,8H,4-5,23H2,1H3,(H2,24,25)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50131702 (CHEMBL3633521) Show SMILES CCCNC1CN(C1)c1c(F)cc2c(c1C)n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F Show InChI InChI=1S/C22H22F3N5O3/c1-3-4-27-11-7-29(8-11)18-10(2)17-12(5-14(18)23)19(31)13(22(32)33)9-30(17)21-16(25)6-15(24)20(26)28-21/h5-6,9,11,27H,3-4,7-8H2,1-2H3,(H2,26,28)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	411	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50131701 (CHEMBL3633522) Show SMILES CC(C)NC1CN(C1)c1c(F)cc2c(c1C)n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F Show InChI InChI=1S/C22H22F3N5O3/c1-9(2)27-11-6-29(7-11)18-10(3)17-12(4-14(18)23)19(31)13(22(32)33)8-30(17)21-16(25)5-15(24)20(26)28-21/h4-5,8-9,11,27H,6-7H2,1-3H3,(H2,26,28)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	433	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50366826 (DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...) Show SMILES C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O |r| Show InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50131704 (CHEMBL3633519) Show SMILES CNC1CN(C1)c1c(F)cc2c(c1C)n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F Show InChI InChI=1S/C20H18F3N5O3/c1-8-15-10(3-12(21)16(8)27-5-9(6-27)25-2)17(29)11(20(30)31)7-28(15)19-14(23)4-13(22)18(24)26-19/h3-4,7,9,25H,5-6H2,1-2H3,(H2,24,26)(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	553	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50131700 (CHEMBL3633523) Show SMILES Cc1c(N2CC(C2)NC(C)(C)C)c(F)cc2c1n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F Show InChI InChI=1S/C23H24F3N5O3/c1-10-17-12(5-14(24)18(10)30-7-11(8-30)29-23(2,3)4)19(32)13(22(33)34)9-31(17)21-16(26)6-15(25)20(27)28-21/h5-6,9,11,29H,7-8H2,1-4H3,(H2,27,28)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	694	n/a	n/a	n/a	n/a	n/a	n/a
Wakunaga Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assay				Eur J Med Chem 103: 354-60 (2015) Article DOI: 10.1016/j.ejmech.2015.08.015 BindingDB Entry DOI: 10.7270/Q22B90V9
					More data for this Ligand-Target Pair