Compile Data Set for Download or QSAR

Found 60 hits with Last Name = 'arai' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50182889 (CHEMBL3818849) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1ccc(I)cc1)[N+]([O-])=O Show InChI InChI=1S/C13H11IN2O5S/c1-22(19,20)15-12-7-4-10(16(17)18)8-13(12)21-11-5-2-9(14)3-6-11/h2-8,15H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of heme catalyzed hydroperoxidase activity of ovine COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrat...				Bioorg Med Chem 24: 3727-33 (2016) Article DOI: 10.1016/j.bmc.2016.06.015 BindingDB Entry DOI: 10.7270/Q2HX1FMD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50410534 (CHEMBL83116) Show SMILES Oc1c(Cl)cc(cc1Cl)-c1cc(Cl)c(O)c(Cl)c1 Show InChI InChI=1S/C12H6Cl4O2/c13-7-1-5(2-8(14)11(7)17)6-3-9(15)12(18)10(16)4-6/h1-4,17-18H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50410534 (CHEMBL83116) Show SMILES Oc1c(Cl)cc(cc1Cl)-c1cc(Cl)c(O)c(Cl)c1 Show InChI InChI=1S/C12H6Cl4O2/c13-7-1-5(2-8(14)11(7)17)6-3-9(15)12(18)10(16)4-6/h1-4,17-18H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50056999 (CHEMBL56367 | nimesulide) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1)[N+]([O-])=O Show InChI InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197882 (CHEMBL3959466) Show SMILES Cc1c(\C=C\c2ccc(Cl)o2)occ1C(O)=O Show InChI InChI=1S/C12H9ClO4/c1-7-9(12(14)15)6-16-10(7)4-2-8-3-5-11(13)17-8/h2-6H,1H3,(H,14,15)/b4-2+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197882 (CHEMBL3959466) Show SMILES Cc1c(\C=C\c2ccc(Cl)o2)occ1C(O)=O Show InChI InChI=1S/C12H9ClO4/c1-7-9(12(14)15)6-16-10(7)4-2-8-3-5-11(13)17-8/h2-6H,1H3,(H,14,15)/b4-2+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301375 (3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...) Show SMILES N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O |r| Show InChI InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50301375 (3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...) Show SMILES N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O |r| Show InChI InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50128688 (CHEMBL3628727) Show SMILES COc1ccc(Oc2cc(ccc2NS(C)(=O)=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H14N2O6S/c1-21-11-4-6-12(7-5-11)22-14-9-10(16(17)18)3-8-13(14)15-23(2,19)20/h3-9,15H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197881 (CHEMBL3890392) Show SMILES Cc1oc(\C=C\c2ccc(Cl)o2)cc1C(O)=O Show InChI InChI=1S/C12H9ClO4/c1-7-10(12(14)15)6-9(16-7)3-2-8-4-5-11(13)17-8/h2-6H,1H3,(H,14,15)/b3-2+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197881 (CHEMBL3890392) Show SMILES Cc1oc(\C=C\c2ccc(Cl)o2)cc1C(O)=O Show InChI InChI=1S/C12H9ClO4/c1-7-10(12(14)15)6-9(16-7)3-2-8-4-5-11(13)17-8/h2-6H,1H3,(H,14,15)/b3-2+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301372 ((E/Z)-3-(4-nitrophenylimino)indolin-2-one | CHEMBL...) Show SMILES [O-][N+](=O)c1ccc(cc1)\N=C1/C(=O)Nc2ccccc12 Show InChI InChI=1S/C14H9N3O3/c18-14-13(11-3-1-2-4-12(11)16-14)15-9-5-7-10(8-6-9)17(19)20/h1-8H,(H,15,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...) Show SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...) Show SMILES OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50301374 (2,4,6-Triiodo-phenol | 2,4,6-Triiodo-phenol(TIP) |...) Show SMILES Oc1c(I)cc(I)cc1I Show InChI InChI=1S/C6H3I3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301380 ((E/Z)-1-methyl-3-(p-tolylimino)indolin-2-one | CHE...) Show SMILES CN1C(=O)\C(=N/c2ccc(C)cc2)c2ccccc12 Show InChI InChI=1S/C16H14N2O/c1-11-7-9-12(10-8-11)17-15-13-5-3-4-6-14(13)18(2)16(15)19/h3-10H,1-2H3/b17-15-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM10304 (1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...) Show SMILES CN1C(=O)C(=O)c2ccccc12 Show InChI InChI=1S/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301373 ((E/Z)-1-methyl-3-(4-nitrophenylimino)indolin-2-one...) Show SMILES CN1C(=O)\C(=N/c2ccc(cc2)[N+]([O-])=O)c2ccccc12 Show InChI InChI=1S/C15H11N3O3/c1-17-13-5-3-2-4-12(13)14(15(17)19)16-10-6-8-11(9-7-10)18(20)21/h2-9H,1H3/b16-14-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50197884 (CHEMBL3969733) Show SMILES Cc1oc(CSCc2cc(C(O)=O)c(C)o2)cc1C(O)=O Show InChI InChI=1S/C14H14O6S/c1-7-11(13(15)16)3-9(19-7)5-21-6-10-4-12(14(17)18)8(2)20-10/h3-4H,5-6H2,1-2H3,(H,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Coimbra Curated by ChEMBL					Assay Description Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...				Eur J Med Chem 121: 823-840 (2016) Article DOI: 10.1016/j.ejmech.2016.02.074 BindingDB Entry DOI: 10.7270/Q26975JG
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301381 ((E/Z)-3-(4-methoxyphenylimino)-1-methylindolin-2-o...) Show SMILES COc1ccc(cc1)\N=C1/C(=O)N(C)c2ccccc12 Show InChI InChI=1S/C16H14N2O2/c1-18-14-6-4-3-5-13(14)15(16(18)19)17-11-7-9-12(20-2)10-8-11/h3-10H,1-2H3/b17-15-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50189601 ((E)-3-(4-methoxyphenylimino)indolin-2-one | (E/Z)-...) Show SMILES COc1ccc(cc1)\N=C1\C(=O)Nc2ccccc12 Show InChI InChI=1S/C15H12N2O2/c1-19-11-8-6-10(7-9-11)16-14-12-4-2-3-5-13(12)17-15(14)18/h2-9H,1H3,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301375 (3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...) Show SMILES N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O |r| Show InChI InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50301377 ((E/Z)-1-methyl-3-(phenylimino)indolin-2-one | CHEM...) Show SMILES CN1C(=O)\C(=N/c2ccccc2)c2ccccc12 Show InChI InChI=1S/C15H12N2O/c1-17-13-10-6-5-9-12(13)14(15(17)18)16-11-7-3-2-4-8-11/h2-10H,1H3/b16-14-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transthyretin (Homo sapiens (Human))	BDBM50301379 ((E/Z)-3-(p-tolylimino)indolin-2-one | CHEMBL571380) Show SMILES Cc1ccc(cc1)\N=C1/C(=O)Nc2ccccc12 Show InChI InChI=1S/C15H12N2O/c1-10-6-8-11(9-7-10)16-14-12-4-2-3-5-13(12)17-15(14)18/h2-9H,1H3,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301378 ((E/Z)-5-iodo-3-(phenylimino)indolin-2-one | CHEMBL...) Show SMILES Ic1ccc2NC(=O)\C(=N/c3ccccc3)c2c1 Show InChI InChI=1S/C14H9IN2O/c15-9-6-7-12-11(8-9)13(14(18)17-12)16-10-4-2-1-3-5-10/h1-8H,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50198047 ((E/Z)-3-(phenylimino)indolin-2-one | 3-(phenylimin...) Show SMILES O=C1Nc2ccccc2\C1=N\c1ccccc1 Show InChI InChI=1S/C14H10N2O/c17-14-13(15-10-6-2-1-3-7-10)11-8-4-5-9-12(11)16-14/h1-9H,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM11022 (2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...) Show SMILES O=C1Nc2ccccc2C1=O Show InChI InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301376 ((E/Z)-3-(4-iodophenylimino)-5-nitroindolin-2-one |...) Show SMILES [O-][N+](=O)c1ccc2NC(=O)\C(=N/c3ccc(I)cc3)c2c1 Show InChI InChI=1S/C14H8IN3O3/c15-8-1-3-9(4-2-8)16-13-11-7-10(18(20)21)5-6-12(11)17-14(13)19/h1-7H,(H,16,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301389 ((E/Z)-5-bromo-3-(4-iodophenylimino)indolin-2-one |...) Show SMILES Brc1ccc2NC(=O)\C(=N/c3ccc(I)cc3)c2c1 Show InChI InChI=1S/C14H8BrIN2O/c15-8-1-6-12-11(7-8)13(14(19)18-12)17-10-4-2-9(16)3-5-10/h1-7H,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301390 ((E/Z)-5-iodo-3-(4-iodophenylimino)indolin-2-one | ...) Show SMILES Ic1ccc(cc1)\N=C1/C(=O)Nc2ccc(I)cc12 Show InChI InChI=1S/C14H8I2N2O/c15-8-1-4-10(5-2-8)17-13-11-7-9(16)3-6-12(11)18-14(13)19/h1-7H,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301388 ((E/Z)-3-(4-iodophenylimino)-5-methylindolin-2-one ...) Show SMILES Cc1ccc2NC(=O)\C(=N/c3ccc(I)cc3)c2c1 Show InChI InChI=1S/C15H11IN2O/c1-9-2-7-13-12(8-9)14(15(19)18-13)17-11-5-3-10(16)4-6-11/h2-8H,1H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301387 ((E/Z)-3-(4-iodophenylimino)-1-methylindolin-2-one ...) Show SMILES CN1C(=O)\C(=N/c2ccc(I)cc2)c2ccccc12 Show InChI InChI=1S/C15H11IN2O/c1-18-13-5-3-2-4-12(13)14(15(18)19)17-11-8-6-10(16)7-9-11/h2-9H,1H3/b17-14-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301386 ((E/Z)-3-(4-iodophenylimino)indolin-2-one | CHEMBL5...) Show SMILES Ic1ccc(cc1)\N=C1/C(=O)Nc2ccccc12 Show InChI InChI=1S/C14H9IN2O/c15-9-5-7-10(8-6-9)16-13-11-3-1-2-4-12(11)17-14(13)18/h1-8H,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301385 ((E/Z)-3-(4-methoxyphenylimino)-5-nitroindolin-2-on...) Show SMILES COc1ccc(cc1)\N=C1/C(=O)Nc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O4/c1-22-11-5-2-9(3-6-11)16-14-12-8-10(18(20)21)4-7-13(12)17-15(14)19/h2-8H,1H3,(H,16,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301384 ((E/Z)-5-iodo-3-(4-methoxyphenylimino)indolin-2-one...) Show SMILES COc1ccc(cc1)\N=C1/C(=O)Nc2ccc(I)cc12 Show InChI InChI=1S/C15H11IN2O2/c1-20-11-5-3-10(4-6-11)17-14-12-8-9(16)2-7-13(12)18-15(14)19/h2-8H,1H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301383 ((E/Z)-5-bromo-3-(4-methoxyphenylimino)indolin-2-on...) Show SMILES COc1ccc(cc1)\N=C1/C(=O)Nc2ccc(Br)cc12 Show InChI InChI=1S/C15H11BrN2O2/c1-20-11-5-3-10(4-6-11)17-14-12-8-9(16)2-7-13(12)18-15(14)19/h2-8H,1H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50301382 ((E/Z)-3-(4-methoxyphenylimino)-5-methylindolin-2-o...) Show SMILES COc1ccc(cc1)\N=C1/C(=O)Nc2ccc(C)cc12 Show InChI InChI=1S/C16H14N2O2/c1-10-3-8-14-13(9-10)15(16(19)18-14)17-11-4-6-12(20-2)7-5-11/h3-9H,1-2H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50182989 (CHEMBL3819010) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1cccc(I)c1)[N+]([O-])=O Show InChI InChI=1S/C13H11IN2O5S/c1-22(19,20)15-12-6-5-10(16(17)18)8-13(12)21-11-4-2-3-9(14)7-11/h2-8,15H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of heme catalyzed hydroperoxidase activity of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrat...				Bioorg Med Chem 24: 3727-33 (2016) Article DOI: 10.1016/j.bmc.2016.06.015 BindingDB Entry DOI: 10.7270/Q2HX1FMD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50182990 (CHEMBL3818762) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1I)[N+]([O-])=O Show InChI InChI=1S/C13H11IN2O5S/c1-22(19,20)15-11-7-6-9(16(17)18)8-13(11)21-12-5-3-2-4-10(12)14/h2-8,15H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of heme catalyzed hydroperoxidase activity of ovine COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrat...				Bioorg Med Chem 24: 3727-33 (2016) Article DOI: 10.1016/j.bmc.2016.06.015 BindingDB Entry DOI: 10.7270/Q2HX1FMD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50182989 (CHEMBL3819010) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1cccc(I)c1)[N+]([O-])=O Show InChI InChI=1S/C13H11IN2O5S/c1-22(19,20)15-12-6-5-10(16(17)18)8-13(12)21-11-4-2-3-9(14)7-11/h2-8,15H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of heme catalyzed hydroperoxidase activity of ovine COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrat...				Bioorg Med Chem 24: 3727-33 (2016) Article DOI: 10.1016/j.bmc.2016.06.015 BindingDB Entry DOI: 10.7270/Q2HX1FMD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50128691 (CHEMBL3628630) Show SMILES COc1cccc(Oc2cc(ccc2NS(C)(=O)=O)[N+]([O-])=O)c1 Show InChI InChI=1S/C14H14N2O6S/c1-21-11-4-3-5-12(9-11)22-14-8-10(16(17)18)6-7-13(14)15-23(2,19)20/h3-9,15H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50128688 (CHEMBL3628727) Show SMILES COc1ccc(Oc2cc(ccc2NS(C)(=O)=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C14H14N2O6S/c1-21-11-4-6-12(7-5-11)22-14-9-10(16(17)18)3-8-13(14)15-23(2,19)20/h3-9,15H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50128748 (CHEMBL3628629) Show SMILES COc1ccccc1Oc1cc(ccc1NS(C)(=O)=O)[N+]([O-])=O Show InChI InChI=1S/C14H14N2O6S/c1-21-12-5-3-4-6-13(12)22-14-9-10(16(17)18)7-8-11(14)15-23(2,19)20/h3-9,15H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50128691 (CHEMBL3628630) Show SMILES COc1cccc(Oc2cc(ccc2NS(C)(=O)=O)[N+]([O-])=O)c1 Show InChI InChI=1S/C14H14N2O6S/c1-21-11-4-3-5-12(9-11)22-14-8-10(16(17)18)6-7-13(14)15-23(2,19)20/h3-9,15H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric method				Bioorg Med Chem 23: 6807-14 (2015) Article DOI: 10.1016/j.bmc.2015.10.007 BindingDB Entry DOI: 10.7270/Q22N543P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50182990 (CHEMBL3818762) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1I)[N+]([O-])=O Show InChI InChI=1S/C13H11IN2O5S/c1-22(19,20)15-11-7-6-9(16(17)18)8-13(11)21-12-5-3-2-4-10(12)14/h2-8,15H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of heme catalyzed hydroperoxidase activity of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrat...				Bioorg Med Chem 24: 3727-33 (2016) Article DOI: 10.1016/j.bmc.2016.06.015 BindingDB Entry DOI: 10.7270/Q2HX1FMD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50182889 (CHEMBL3818849) Show SMILES CS(=O)(=O)Nc1ccc(cc1Oc1ccc(I)cc1)[N+]([O-])=O Show InChI InChI=1S/C13H11IN2O5S/c1-22(19,20)15-12-7-4-10(16(17)18)8-13(12)21-11-5-2-9(14)3-6-11/h2-8,15H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of heme catalyzed hydroperoxidase activity of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrat...				Bioorg Med Chem 24: 3727-33 (2016) Article DOI: 10.1016/j.bmc.2016.06.015 BindingDB Entry DOI: 10.7270/Q2HX1FMD
					More data for this Ligand-Target Pair

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