Compile Data Set for Download or QSAR

Found 14 hits with Last Name = 'bachman' and Initial = 'jl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O Show InChI InChI=1S/C13H15N5O3/c1-2-17-12(20)8-5-7(10(15)19)9(14)16-11(8)18(13(17)21)6-3-4-6/h5-6H,2-4H2,1H3,(H2,14,16)(H2,15,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description ATP competitive inhibition of human eEF-2K using 5 uM ATP				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O Show InChI InChI=1S/C13H15N5O3/c1-2-17-12(20)8-5-7(10(15)19)9(14)16-11(8)18(13(17)21)6-3-4-6/h5-6H,2-4H2,1H3,(H2,14,16)(H2,15,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053583 (CHEMBL3327225) Show SMILES CCCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O Show InChI InChI=1S/C14H17N5O3/c1-2-5-18-13(21)9-6-8(11(16)20)10(15)17-12(9)19(14(18)22)7-3-4-7/h6-7H,2-5H2,1H3,(H2,15,17)(H2,16,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053577 (CHEMBL3326370) Show SMILES CCn1c2nc(N)c(cc2c(=O)n(CC)c1=O)C(N)=O Show InChI InChI=1S/C12H15N5O3/c1-3-16-10-7(11(19)17(4-2)12(16)20)5-6(9(14)18)8(13)15-10/h5H,3-4H2,1-2H3,(H2,13,15)(H2,14,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053587 (CHEMBL3327224) Show SMILES Cn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O Show InChI InChI=1S/C12H13N5O3/c1-16-11(19)7-4-6(9(14)18)8(13)15-10(7)17(12(16)20)5-2-3-5/h4-5H,2-3H2,1H3,(H2,13,15)(H2,14,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053640 (CHEMBL3327223) Show SMILES NC(=O)c1cc2c(nc1N)n(C1CC1)c(=O)[nH]c2=O Show InChI InChI=1S/C11H11N5O3/c12-7-5(8(13)17)3-6-9(14-7)16(4-1-2-4)11(19)15-10(6)18/h3-4H,1-2H2,(H2,12,14)(H2,13,17)(H,15,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053581 (CHEMBL3327227) Show SMILES NC(=O)c1cc2c(nc1N)n(C1CC1)c(=O)n(Cc1ccc(N)cc1)c2=O Show InChI InChI=1S/C18H18N6O3/c19-10-3-1-9(2-4-10)8-23-17(26)13-7-12(15(21)25)14(20)22-16(13)24(18(23)27)11-5-6-11/h1-4,7,11H,5-6,8,19H2,(H2,20,22)(H2,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053579 (CHEMBL3326368) Show SMILES CCOC(=O)c1cc2c(nc1N)n(C1CC1)c(=O)n(CC)c2=O Show InChI InChI=1S/C15H18N4O4/c1-3-18-13(20)10-7-9(14(21)23-4-2)11(16)17-12(10)19(15(18)22)8-5-6-8/h7-8H,3-6H2,1-2H3,(H2,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053582 (CHEMBL3327226) Show SMILES NC(=O)c1cc2c(nc1N)n(C1CC1)c(=O)n(Cc1ccc(cc1)[N+]([O-])=O)c2=O Show InChI InChI=1S/C18H16N6O5/c19-14-12(15(20)25)7-13-16(21-14)23(10-5-6-10)18(27)22(17(13)26)8-9-1-3-11(4-2-9)24(28)29/h1-4,7,10H,5-6,8H2,(H2,19,21)(H2,20,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053578 (CHEMBL3326369) Show SMILES CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C#N Show InChI InChI=1S/C13H13N5O2/c1-2-17-12(19)9-5-7(6-14)10(15)16-11(9)18(13(17)20)8-3-4-8/h5,8H,2-4H2,1H3,(H2,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053575 (CHEMBL3326372) Show SMILES CCn1c(=O)cc(N)n(C2CC2)c1=O Show InChI InChI=1S/C9H13N3O2/c1-2-11-8(13)5-7(10)12(9(11)14)6-3-4-6/h5-6H,2-4,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053574 (CHEMBL3326373) Show SMILES CCn1c(=O)c(C=O)c(N)n(C2CC2)c1=O Show InChI InChI=1S/C10H13N3O3/c1-2-12-9(15)7(5-14)8(11)13(10(12)16)6-3-4-6/h5-6H,2-4,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053576 (CHEMBL3326371) Show SMILES Cn1c2nc(N)c(cc2c(=O)n(C)c1=O)C(N)=O Show InChI InChI=1S/C10H11N5O3/c1-14-8-5(9(17)15(2)10(14)18)3-4(7(12)16)6(11)13-8/h3H,1-2H3,(H2,11,13)(H2,12,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053580 (CHEMBL3327228) Show SMILES CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=S Show InChI InChI=1S/C13H15N5O2S/c1-2-17-12(19)8-5-7(10(15)21)9(14)16-11(8)18(13(17)20)6-3-4-6/h5-6H,2-4H2,1H3,(H2,14,16)(H2,15,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair