Found 122 hits with Last Name = 'backos' and Initial = 'ds' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50105838
(FENOBAM)Show InChI InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50105838
(FENOBAM)Show InChI InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450061
(CHEMBL4166199)Show InChI InChI=1S/C13H11N3O2/c1-8-3-5-10(6-4-8)16-13(17)12-11(7-18-15-12)9(2)14-16/h3-7H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450078
(CHEMBL4167825)Show InChI InChI=1S/C12H7Cl2N3O2/c1-6-10-5-19-16-11(10)12(18)17(15-6)9-3-7(13)2-8(14)4-9/h2-5H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450077
(CHEMBL4164391)Show SMILES Cc1nn(-c2ccc(cc2)[N+]([O-])=O)c(=O)c2nocc12 Show InChI InChI=1S/C12H8N4O4/c1-7-10-6-20-14-11(10)12(17)15(13-7)8-2-4-9(5-3-8)16(18)19/h2-6H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450076
(CHEMBL4163974)Show InChI InChI=1S/C12H7F2N3O2/c1-6-8-5-19-16-11(8)12(18)17(15-6)10-3-2-7(13)4-9(10)14/h2-5H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450074
(CHEMBL4171187)Show InChI InChI=1S/C13H11N3O3/c1-8-11-7-19-15-12(11)13(17)16(14-8)9-3-5-10(18-2)6-4-9/h3-7H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450060
(CHEMBL4172276)Show SMILES Cc1nn(-c2cccc(c2)[N+]([O-])=O)c(=O)c2nocc12 Show InChI InChI=1S/C12H8N4O4/c1-7-10-6-20-14-11(10)12(17)15(13-7)8-3-2-4-9(5-8)16(18)19/h2-6H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450059
(CHEMBL4160584)Show InChI InChI=1S/C12H8FN3O2/c1-7-10-6-18-15-11(10)12(17)16(14-7)9-4-2-8(13)3-5-9/h2-6H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50450075
(CHEMBL4174628)Show InChI InChI=1S/C12H9N3O2/c1-8-10-7-17-14-11(10)12(16)15(13-8)9-5-3-2-4-6-9/h2-7H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Montana
Curated by ChEMBL
| Assay Description Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting method |
Bioorg Med Chem 26: 4797-4803 (2018)
Article DOI: 10.1016/j.bmc.2018.08.012 BindingDB Entry DOI: 10.7270/Q2Q242TX |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK1 (unknown origin) |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK2 (unknown origin) |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human)) | BDBM50111384
(CHEMBL3604794)Show SMILES Oc1c(F)cc(cc1F)-c1cnccc1-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C21H18F2N2O2/c22-19-11-15(12-20(23)21(19)26)18-13-24-6-5-17(18)14-1-3-16(4-2-14)25-7-9-27-10-8-25/h1-6,11-13,26H,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK3 (unknown origin) |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50111384
(CHEMBL3604794)Show SMILES Oc1c(F)cc(cc1F)-c1cnccc1-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C21H18F2N2O2/c22-19-11-15(12-20(23)21(19)26)18-13-24-6-5-17(18)14-1-3-16(4-2-14)25-7-9-27-10-8-25/h1-6,11-13,26H,7-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK2 (unknown origin) |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human)) | BDBM50111384
(CHEMBL3604794)Show SMILES Oc1c(F)cc(cc1F)-c1cnccc1-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C21H18F2N2O2/c22-19-11-15(12-20(23)21(19)26)18-13-24-6-5-17(18)14-1-3-16(4-2-14)25-7-9-27-10-8-25/h1-6,11-13,26H,7-10H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK1 (unknown origin) |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK3 (unknown origin) |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK4 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assay |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568111
(CHEMBL4878141 | US11851436, Compound A1-12)Show SMILES COC(=O)CCc1ccc(cc1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564453
(CHEMBL4794096)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C#N)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568112
(CHEMBL4851452)Show SMILES COC(=O)CCCc1ccc(cc1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568106
(CHEMBL4849660 | US11851436, Compound A1-4)Show SMILES Oc1c(F)cc(Nc2ncc3ncn(-c4ccc(CCN5CCOCC5)cc4)c3n2)cc1F | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK3 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assay |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564457
(CHEMBL4800500)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCO)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assay |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568105
(CHEMBL4858455 | US11851436, Compound A1-3)Show SMILES Oc1c(F)cc(Nc2ncc3ncn(-c4ccc(cc4)N4CCOCC4)c3n2)cc1F | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568114
(CHEMBL4857399)Show SMILES Oc1c(F)cc(Nc2ncc3ccn(-c4ccc(cc4)N4CCOCC4)c3n2)cc1F | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human)) | BDBM25017
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
| Assay Description Inhibition of RSK1 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assay |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115303 BindingDB Entry DOI: 10.7270/Q2XW4PCP |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564458
(CHEMBL4788376)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCC#N)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568115
(CHEMBL4864190)Show SMILES CN1CCN(CC1)c1ccc(cc1)-n1ccc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564448
(CHEMBL4788980)Show SMILES CCN(CC)CCCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564449
(CHEMBL4779166)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cc(F)ccc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM4817
(N-[2-(dimethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo...)Show SMILES CN(C)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C20H23FN4O2/c1-11-17(23-12(2)18(11)20(27)22-7-8-25(3)4)10-15-14-9-13(21)5-6-16(14)24-19(15)26/h5-6,9-10,23H,7-8H2,1-4H3,(H,22,27)(H,24,26)/b15-10- | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568104
(CHEMBL4858257 | US11851436, Compound A1-2) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564459
(CHEMBL4781578)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCC(N)=O)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564446
(CHEMBL3542344)Show SMILES CCNCCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM4814
(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12- | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564450
(CHEMBL4786972)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cc(Cl)ccc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564447
(CHEMBL4799580)Show SMILES CN(C)CCCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568109
(CHEMBL4861235 | US11851436, Compound A1-10)Show SMILES Oc1cccc(c1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568110
(CHEMBL4865383 | US11851436, Compound A1-11)Show SMILES Oc1ccc(cc1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564451
(CHEMBL4782796)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cc(Br)ccc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564454
(CHEMBL4792246)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CNC(N)=O)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM4813
(N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccccc23)c1C Show InChI InChI=1S/C22H28N4O2/c1-5-26(6-2)12-11-23-22(28)20-14(3)19(24-15(20)4)13-17-16-9-7-8-10-18(16)25-21(17)27/h7-10,13,24H,5-6,11-12H2,1-4H3,(H,23,28)(H,25,27)/b17-13- | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human)) | BDBM50564453
(CHEMBL4794096)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(cc23)C#N)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human)) | BDBM50568113
(CHEMBL4873445) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564455
(CHEMBL4781062)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCOC)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564462
(CHEMBL4796639)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCN=[N+]=[N-])cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human)) | BDBM50564459
(CHEMBL4781578)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCC(N)=O)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human)) | BDBM50564461
(CHEMBL4795330)Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCNC(C)=O)cc23)c1C | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112316 BindingDB Entry DOI: 10.7270/Q2348Q5W |
More data for this Ligand-Target Pair | |