BindingDB PrimarySearch

Found 12 hits with Last Name = 'baculi' and Initial = 'f'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50062351 ((R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-met...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant 92 kDa gelatinase MMP-9 at 100 uM				Bioorg Med Chem Lett 5: 1637-1642 (1995) Article DOI: 10.1016/0960-894X(95)00282-X BindingDB Entry DOI: 10.7270/Q2J38SJB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50062351 ((R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-met...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant interstitial collagenase MMP-1 at 100 uM				Bioorg Med Chem Lett 5: 1637-1642 (1995) Article DOI: 10.1016/0960-894X(95)00282-X BindingDB Entry DOI: 10.7270/Q2J38SJB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50545275 (CHEMBL4645677) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of adrenergic receptor alpha1 (unknown origin)				J Med Chem 63: 6648-6676 (2020) Article DOI: 10.1021/acs.jmedchem.9b01928 BindingDB Entry DOI: 10.7270/Q2KS6W4N
Celgene Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50062351 ((R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-met...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant matrix metalloproteinase-3 (Stromelysin) at 100 uM				Bioorg Med Chem Lett 5: 1637-1642 (1995) Article DOI: 10.1016/0960-894X(95)00282-X BindingDB Entry DOI: 10.7270/Q2J38SJB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human))	BDBM65497 (CC-220 (Compound 6) \| US9694015, 6.4S) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.0	n/a
Celgene Corporation					Assay Description The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...				J Med Chem 61: 535-542 (2017) Article DOI: 10.1021/acs.jmedchem.6b01921 BindingDB Entry DOI: 10.7270/Q2PC30HG
Celgene Corporation					More data for this Ligand-Target Pair				3D Structure (crystal)
Stromelysin-1 (Homo sapiens (Human))	BDBM50284909 ((R)-3-Benzo[1,3]dioxol-5-yl-4-((S)-6-mercapto-5-me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant matrix metalloproteinase-3 (Stromelysin) at 10 uM				Bioorg Med Chem Lett 5: 1637-1642 (1995) Article DOI: 10.1016/0960-894X(95)00282-X BindingDB Entry DOI: 10.7270/Q2J38SJB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50545276 (CHEMBL4637801) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of adrenergic receptor alpha1 (unknown origin)				J Med Chem 63: 6648-6676 (2020) Article DOI: 10.1021/acs.jmedchem.9b01928 BindingDB Entry DOI: 10.7270/Q2KS6W4N
Celgene Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50213210 (FUTOENONE) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant matrix metalloprotease-3 (Stromelysin) at 10 uM				Bioorg Med Chem Lett 5: 1637-1642 (1995) Article DOI: 10.1016/0960-894X(95)00282-X BindingDB Entry DOI: 10.7270/Q2J38SJB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human))	BDBM65456 (19171-19-8 \| 4-amino-2-(2,6-dioxopiperidin-3-yl)is...) Show SMILES Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.0	n/a
Celgene Corporation					Assay Description The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...				J Med Chem 61: 535-542 (2017) Article DOI: 10.1021/acs.jmedchem.6b01921 BindingDB Entry DOI: 10.7270/Q2PC30HG
Celgene Corporation					More data for this Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon (Homo sapiens (Human))	BDBM65454 (191732-72-6 \| CC-5013 \| Lenalidomide \| Revimid \| R...) Show SMILES Nc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.0	n/a
Celgene Corporation					Assay Description The 6XHis-tagged full length human CRBN bound to full length human DDB1 used in the assay was purified as described elsewhere with the exception that...				J Med Chem 61: 535-542 (2017) Article DOI: 10.1021/acs.jmedchem.6b01921 BindingDB Entry DOI: 10.7270/Q2PC30HG
Celgene Corporation					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50545275 (CHEMBL4645677) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Agonist activity at D2S (unknown origin)				J Med Chem 63: 6648-6676 (2020) Article DOI: 10.1021/acs.jmedchem.9b01928 BindingDB Entry DOI: 10.7270/Q2KS6W4N
Celgene Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50545276 (CHEMBL4637801) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Agonist activity at D2S (unknown origin)				J Med Chem 63: 6648-6676 (2020) Article DOI: 10.1021/acs.jmedchem.9b01928 BindingDB Entry DOI: 10.7270/Q2KS6W4N
Celgene Corporation Curated by ChEMBL					More data for this Ligand-Target Pair