BindingDB PrimarySearch

Found 22188 hits with Last Name = 'berg' and Initial = 'm'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434903 (CHEMBL2385223) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of N-arachidonoyldopamine-induced activity after 5 mins by FLIPR a...				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (RAT)	BDBM82300 (CAS_59763-91-6 \| NSC_41735 \| PP, rat) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	0.00270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (RAT)	BDBM82286 (CAS_59763-91-6 \| PP, human \| PP,SALMON) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (RAT)	BDBM82297 (CAS_59763-91-6 \| PP, BOVINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.00600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (RAT)	BDBM85378 (PP, guinea pig) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50398494 (CHEMBL2177429) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of N-acetyldopamine-induced activity after 5 mins by FLIPR assay				Bioorg Med Chem 21: 6657-64 (2013) Article DOI: 10.1016/j.bmc.2013.08.015 BindingDB Entry DOI: 10.7270/Q26Q1ZPN
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50398494 (CHEMBL2177429) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of N-acetyldopamine-induced activity after 5 mins by FLIPR assay				J Med Chem 55: 8392-408 (2012) Article DOI: 10.1021/jm300780p BindingDB Entry DOI: 10.7270/Q2TX3GH1
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic polypeptide receptor 1 (GUINEA PIG)	BDBM82297 (CAS_59763-91-6 \| PP, BOVINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM570555 (US11440884, Example 18 \| [4-(propan-2-yloxy)phenyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description R-SAT's were generally performed with 50 ng/well of receptor and 20 ng/well of β-galactosidase plasmid DNA. All receptor constructs used wer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC864D
TBA					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50049553 (CHEMBL2177428) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of N-arachidonoyl dopamine-induced activation by FLIPR assay				Bioorg Med Chem Lett 25: 2326-30 (2015) Article DOI: 10.1016/j.bmcl.2015.04.024 BindingDB Entry DOI: 10.7270/Q2Z60QSC
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50049553 (CHEMBL2177428) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of N-arachidonoyl dopamine-induced activity by FLIPR assay				Eur J Med Chem 93: 101-8 (2015) Article DOI: 10.1016/j.ejmech.2015.02.001 BindingDB Entry DOI: 10.7270/Q2N0188S
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50073160 (CHEMBL3407762) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of N-arachidonoyl dopamine-induced activity by FLIPR assay				Eur J Med Chem 93: 101-8 (2015) Article DOI: 10.1016/j.ejmech.2015.02.001 BindingDB Entry DOI: 10.7270/Q2N0188S
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl endopeptidase (Sus scrofa)	BDBM50155838 ((S)-1-((S)-1-(4-phenylbutanoyl)pyrrolidine-2-carbo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibitory activity against prolyl oligopeptidase of porcine brain homogenate				J Med Chem 47: 5605-7 (2004) Article DOI: 10.1021/jm049503w BindingDB Entry DOI: 10.7270/Q25D8R9G
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50061298 (CHEMBL3393837) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 assessed as inhibition of NADA-induced effect at 1 uM by FLIPR assay				Bioorg Med Chem Lett 25: 803-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.086 BindingDB Entry DOI: 10.7270/Q2JD4ZG3
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50366620 (RESINIFERATOXIN) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro binding affinity towards vanilloid receptor by [3H]RTX displacement.				Bioorg Med Chem Lett 9: 2909-14 (1999) BindingDB Entry DOI: 10.7270/Q2HT2PTB
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50341508 ((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50128911 (CHEMBL3627723) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of NADA-induced activation by FLIPR assay				Bioorg Med Chem 23: 6844-54 (2015) Article DOI: 10.1016/j.bmc.2015.10.001 BindingDB Entry DOI: 10.7270/Q2DZ0B4X
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50128922 (CHEMBL3627950) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of NADA-induced activation by FLIPR assay				Bioorg Med Chem 23: 6844-54 (2015) Article DOI: 10.1016/j.bmc.2015.10.001 BindingDB Entry DOI: 10.7270/Q2DZ0B4X
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl endopeptidase (Sus scrofa)	BDBM50155839 ((S)-1-[(R)-2-(4-Phenyl-butyryl)-cyclopent-2-enecar...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibitory activity against prolyl oligopeptidase of porcine brain homogenate				J Med Chem 47: 5605-7 (2004) Article DOI: 10.1021/jm049503w BindingDB Entry DOI: 10.7270/Q25D8R9G
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic polypeptide receptor 1 (GUINEA PIG)	BDBM82286 (CAS_59763-91-6 \| PP, human \| PP,SALMON) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM82297 (CAS_59763-91-6 \| PP, BOVINE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM570569 (US11440884, Example 30) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description R-SAT's were generally performed with 50 ng/well of receptor and 20 ng/well of β-galactosidase plasmid DNA. All receptor constructs used wer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC864D
TBA					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (GUINEA PIG)	BDBM84999 (PYY,[leu31,Pro34], human) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (GUINEA PIG)	BDBM82276 (L31,P34-NPY,human \| NPY Leu31, Pro34, human, rat \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM82286 (CAS_59763-91-6 \| PP, human \| PP,SALMON) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176555 (US9120756, 17) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of NADA-induced intracellular calcium level preincubated with cells ...				Bioorg Med Chem Lett 27: 4383-4388 (2017) Article DOI: 10.1016/j.bmcl.2017.08.020 BindingDB Entry DOI: 10.7270/Q2CF9SPD
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50073159 (CHEMBL3407765) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of N-arachidonoyl dopamine-induced activity by FLIPR assay				Eur J Med Chem 93: 101-8 (2015) Article DOI: 10.1016/j.ejmech.2015.02.001 BindingDB Entry DOI: 10.7270/Q2N0188S
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50366620 (RESINIFERATOXIN) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell system				Bioorg Med Chem 17: 690-8 (2009) Article DOI: 10.1016/j.bmc.2008.11.085 BindingDB Entry DOI: 10.7270/Q2CJ8FCW
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50366620 (RESINIFERATOXIN) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from rat TRV1 expressed in CHO cells by competitive binding assay				Bioorg Med Chem Lett 21: 299-302 (2010) Article DOI: 10.1016/j.bmcl.2010.11.012 BindingDB Entry DOI: 10.7270/Q2J967BB
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (GUINEA PIG)	BDBM50005530 (CHEMBL267633 \| D-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-G...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Pancreatic polypeptide receptor 1 (GUINEA PIG)	BDBM82300 (CAS_59763-91-6 \| NSC_41735 \| PP, rat) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Pancreatic polypeptide receptor 1 (GUINEA PIG)	BDBM85378 (PP, guinea pig) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	0.0460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (GUINEA PIG)	BDBM82421 (CAS_81858-94-8 \| PYY, porcine) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	0.0480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50442379 (CHEMBL2442912) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of N-acetyldopamine-induced activity after 5 mins by FLIPR assay				Bioorg Med Chem 21: 6657-64 (2013) Article DOI: 10.1016/j.bmc.2013.08.015 BindingDB Entry DOI: 10.7270/Q26Q1ZPN
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50266003 (CHEMBL4091152) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Competitive inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate ...				J Med Chem 60: 3383-3404 (2017) Article DOI: 10.1021/acs.jmedchem.7b00055 BindingDB Entry DOI: 10.7270/Q26112SB
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50071654 (3-{1-[4-(5-Methylsulfanyl-1,1,3-trioxo-1,3-dihydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Ability to displace beta ([125I]-iodo-4-hydroxyphenyl)-ethylaminomethyl tetralone from human cloned Alpha-1a adrenergic receptor stably expressed in ...				Bioorg Med Chem Lett 8: 2467-72 (1999) BindingDB Entry DOI: 10.7270/Q2NP23K1
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM85378 (PP, guinea pig) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (RAT)	BDBM50005530 (CHEMBL267633 \| D-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-G...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Prolyl endopeptidase (Sus scrofa)	BDBM50051495 ((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibitory activity against prolyl oligopeptidase of porcine brain homogenate				J Med Chem 47: 5605-7 (2004) Article DOI: 10.1021/jm049503w BindingDB Entry DOI: 10.7270/Q25D8R9G
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (RAT)	BDBM82276 (L31,P34-NPY,human \| NPY Leu31, Pro34, human, rat \|...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM570568 (US11440884, Example 29) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description R-SAT's were generally performed with 50 ng/well of receptor and 20 ng/well of β-galactosidase plasmid DNA. All receptor constructs used wer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC864D
TBA					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50071655 (3-{1-[4-(5-Methoxy-1,1,3-trioxo-1,3-dihydro-1lambd...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Ability to displace beta ([125I]-iodo-4-hydroxyphenyl)-ethylaminomethyl tetralone from human cloned Alpha-1a adrenergic receptor stably expressed in ...				Bioorg Med Chem Lett 8: 2467-72 (1999) BindingDB Entry DOI: 10.7270/Q2NP23K1
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (GUINEA PIG)	BDBM85534 (NPY, zebrafish) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Peptides 20: 1043-53 (1999) Article DOI: 10.1016/s0196-9781(99)00098-4 BindingDB Entry DOI: 10.7270/Q2BR8QQF
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM82300 (CAS_59763-91-6 \| NSC_41735 \| PP, rat) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	0.0710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Regul Pept 29-37 (1998) Article DOI: 10.1016/s0167-0115(98)00050-0 BindingDB Entry DOI: 10.7270/Q2DV1HDX
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50247744 (CHEMBL504725 \| [(1R,2R,6R,10S,11R,15S,17R)-13-benz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell system				Bioorg Med Chem 17: 690-8 (2009) Article DOI: 10.1016/j.bmc.2008.11.085 BindingDB Entry DOI: 10.7270/Q2CJ8FCW
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50341508 ((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50071647 (3-{1-[4-(5-Chloro-1,1,3-trioxo-1,3-dihydro-1lambda...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Compound was evaluated for its affinity for Alpha-1a adrenergic receptor in human aorta preparations				Bioorg Med Chem Lett 8: 2467-72 (1999) BindingDB Entry DOI: 10.7270/Q2NP23K1
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM570567 (US11440884, Example 28) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description R-SAT's were generally performed with 50 ng/well of receptor and 20 ng/well of β-galactosidase plasmid DNA. All receptor constructs used wer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC864D
TBA					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50071652 (6-Fluoro-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Ability to displace beta ([125I]-iodo-4-hydroxyphenyl)-ethylamino methyl tetralone from human cloned Alpha-1a adrenergic receptor stably expressed in...				Bioorg Med Chem Lett 8: 2467-72 (1999) BindingDB Entry DOI: 10.7270/Q2NP23K1
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50374443 (CHEMBL272715) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H](S)-N-(2-(1H-pyrrol-1-yl)phenyl)-1-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)acetyl)pyrrolidine-2-carboxamide from human OX2R exp...				Bioorg Med Chem Lett 18: 1425-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.001 BindingDB Entry DOI: 10.7270/Q2N87BM4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 22188 total ) | Next | Last >>