Compile Data Set for Download or QSAR

Found 240 hits with Last Name = 'bezencon' and Initial = 'o'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372453 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Cn1ccc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C20H17F2N5O/c1-26-7-6-15-8-13(3-5-18(15)26)10-20(28)24-19-11-23-27(25-19)12-14-2-4-16(21)17(22)9-14/h2-9,11H,10,12H2,1H3,(H,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372463 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1F Show InChI InChI=1S/C20H18F4N6O/c21-15-3-1-14(7-16(15)22)11-30-26-10-17(28-30)27-19(31)8-13-2-4-18(25-9-13)29-6-5-20(23,24)12-29/h1-4,7,9-10H,5-6,8,11-12H2,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372533 (2-(1-Methyl-1H-indol-5-yl)-N-[2-(4-trifluoromethox...) Show SMILES Cn1ccc2cc(CC(=O)Nc3cnn(Cc4ccc(OC(F)(F)F)cc4)n3)ccc12 Show InChI InChI=1S/C21H18F3N5O2/c1-28-9-8-16-10-15(4-7-18(16)28)11-20(30)26-19-12-25-29(27-19)13-14-2-5-17(6-3-14)31-21(22,23)24/h2-10,12H,11,13H2,1H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372629 (N-[2-(3-Fluoro-4-trifluoromethoxy-benzyl)-2H-[1,2,...) Show SMILES Cn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(OC(F)(F)F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C20H16F4N6O2/c1-29-16-4-2-12(6-14(16)9-25-29)8-19(31)27-18-10-26-30(28-18)11-13-3-5-17(15(21)7-13)32-20(22,23)24/h2-7,9-10H,8,11H2,1H3,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372452 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Cn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C19H16F2N6O/c1-26-17-5-3-12(6-14(17)9-22-26)8-19(28)24-18-10-23-27(25-18)11-13-2-4-15(20)16(21)7-13/h2-7,9-10H,8,11H2,1H3,(H,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372465 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES CN1C(=O)C(C)(C)c2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C22H21F2N5O2/c1-22(2)15-8-13(5-7-18(15)28(3)21(22)31)10-20(30)26-19-11-25-29(27-19)12-14-4-6-16(23)17(24)9-14/h4-9,11H,10,12H2,1-3H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372473 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES CCn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C20H18F2N6O/c1-2-27-18-6-4-13(7-15(18)10-23-27)9-20(29)25-19-11-24-28(26-19)12-14-3-5-16(21)17(22)8-14/h3-8,10-11H,2,9,12H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372534 (2-(1-Methyl-1H-indazol-5-yl)-N-[2-(4-trifluorometh...) Show SMILES Cn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(OC(F)(F)F)cc4)n3)ccc12 Show InChI InChI=1S/C20H17F3N6O2/c1-28-17-7-4-14(8-15(17)10-24-28)9-19(30)26-18-11-25-29(27-18)12-13-2-5-16(6-3-13)31-20(21,22)23/h2-8,10-11H,9,12H2,1H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372536 (2-[6-(3,3-Difluoro-pyrrolidin-1-yl)-pyridin-3-yl]-...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1 Show InChI InChI=1S/C20H19F3N6O/c21-16-4-1-14(2-5-16)12-29-25-11-17(27-29)26-19(30)9-15-3-6-18(24-10-15)28-8-7-20(22,23)13-28/h1-6,10-11H,7-9,12-13H2,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372477 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Cc1cc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc2[nH]1 Show InChI InChI=1S/C20H17F2N5O/c1-12-6-15-7-13(3-5-18(15)24-12)9-20(28)25-19-10-23-27(26-19)11-14-2-4-16(21)17(22)8-14/h2-8,10,24H,9,11H2,1H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372637 (2-(1,3-Dimethyl-1H-indazol-5-yl)-N-[2-(3-fluoro-4-...) Show SMILES Cc1nn(C)c2ccc(CC(=O)Nc3cnn(Cc4ccc(OC(F)(F)F)c(F)c4)n3)cc12 Show InChI InChI=1S/C21H18F4N6O2/c1-12-15-7-13(3-5-17(15)30(2)28-12)9-20(32)27-19-10-26-31(29-19)11-14-4-6-18(16(22)8-14)33-21(23,24)25/h3-8,10H,9,11H2,1-2H3,(H,27,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372496 (N-[2-(4-Fluoro-benzyl)-2H-[1,2,3]triazol-4-yl]-2-(...) Show SMILES Cn1ccc2cc(CC(=O)Nc3cnn(Cc4ccc(F)cc4)n3)ccc12 Show InChI InChI=1S/C20H18FN5O/c1-25-9-8-16-10-15(4-7-18(16)25)11-20(27)23-19-12-22-26(24-19)13-14-2-5-17(21)6-3-14/h2-10,12H,11,13H2,1H3,(H,23,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372521 (N-[2-(3,5-Difluoro-4-methoxy-benzyl)-2H-[1,2,3]tri...) Show SMILES COc1c(F)cc(Cn2ncc(NC(=O)Cc3ccc4n(C)ccc4c3)n2)cc1F Show InChI InChI=1S/C21H19F2N5O2/c1-27-6-5-15-7-13(3-4-18(15)27)10-20(29)25-19-11-24-28(26-19)12-14-8-16(22)21(30-2)17(23)9-14/h3-9,11H,10,12H2,1-2H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372622 (N-[2-(4-Difluoromethoxy-3-fluoro-benzyl)-2H-[1,2,3...) Show SMILES FC(F)Oc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1F Show InChI InChI=1S/C21H19F5N6O2/c22-15-7-14(1-3-16(15)34-20(23)24)11-32-28-10-17(30-32)29-19(33)8-13-2-4-18(27-9-13)31-6-5-21(25,26)12-31/h1-4,7,9-10,20H,5-6,8,11-12H2,(H,29,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372588 (N-[2-(3,5-Difluoro-4-methoxy-benzyl)-2H-[1,2,3]tri...) Show SMILES COc1c(F)cc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1F Show InChI InChI=1S/C21H20F4N6O2/c1-33-20-15(22)6-14(7-16(20)23)11-31-27-10-17(29-31)28-19(32)8-13-2-3-18(26-9-13)30-5-4-21(24,25)12-30/h2-3,6-7,9-10H,4-5,8,11-12H2,1H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372581 (N-[2-(4-Cyano-3-fluoro-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1cn(C)c2ccc(CC(=O)Nc3cnn(Cc4ccc(C#N)c(F)c4)n3)cc12 Show InChI InChI=1S/C22H19FN6O/c1-14-12-28(2)20-6-4-15(7-18(14)20)9-22(30)26-21-11-25-29(27-21)13-16-3-5-17(10-24)19(23)8-16/h3-8,11-12H,9,13H2,1-2H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372636 (2-(1-Ethyl-1H-indazol-5-yl)-N-[2-(3-fluoro-4-trifl...) Show SMILES CCn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(OC(F)(F)F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C21H18F4N6O2/c1-2-30-17-5-3-13(7-15(17)10-26-30)9-20(32)28-19-11-27-31(29-19)12-14-4-6-18(16(22)8-14)33-21(23,24)25/h3-8,10-11H,2,9,12H2,1H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372535 (2-[4-(3-Methyl-oxetan-3-yl)-phenyl]-N-[2-(4-triflu...) Show SMILES CC1(COC1)c1ccc(CC(=O)Nc2cnn(Cc3ccc(OC(F)(F)F)cc3)n2)cc1 Show InChI InChI=1S/C22H21F3N4O3/c1-21(13-31-14-21)17-6-2-15(3-7-17)10-20(30)27-19-11-26-29(28-19)12-16-4-8-18(9-5-16)32-22(23,24)25/h2-9,11H,10,12-14H2,1H3,(H,27,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372468 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES CC1(COC1)c1ccc(CC(=O)Nc2cnn(Cc3ccc(F)c(F)c3)n2)cc1 Show InChI InChI=1S/C21H20F2N4O2/c1-21(12-29-13-21)16-5-2-14(3-6-16)9-20(28)25-19-10-24-27(26-19)11-15-4-7-17(22)18(23)8-15/h2-8,10H,9,11-13H2,1H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372464 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCCC3)n2)cc1F Show InChI InChI=1S/C20H20F2N6O/c21-16-5-3-15(9-17(16)22)13-28-24-12-18(26-28)25-20(29)10-14-4-6-19(23-11-14)27-7-1-2-8-27/h3-6,9,11-12H,1-2,7-8,10,13H2,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372462 (2-(6-Diethylamino-pyridin-3-yl)-N-[2-(3,4-difluoro...) Show SMILES CCN(CC)c1ccc(CC(=O)Nc2cnn(Cc3ccc(F)c(F)c3)n2)cn1 Show InChI InChI=1S/C20H22F2N6O/c1-3-27(4-2)19-8-6-14(11-23-19)10-20(29)25-18-12-24-28(26-18)13-15-5-7-16(21)17(22)9-15/h5-9,11-12H,3-4,10,13H2,1-2H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372591 (N-[2-(3,5-Difluoro-4-methoxy-benzyl)-2H-[1,2,3]tri...) Show SMILES COc1c(F)cc(Cn2ncc(NC(=O)Cc3ccc4n(C)cc(C)c4c3)n2)cc1F Show InChI InChI=1S/C22H21F2N5O2/c1-13-11-28(2)19-5-4-14(6-16(13)19)9-21(30)26-20-10-25-29(27-20)12-15-7-17(23)22(31-3)18(24)8-15/h4-8,10-11H,9,12H2,1-3H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372628 (N-[2-(3-Fluoro-4-trifluoromethoxy-benzyl)-2H-[1,2,...) Show SMILES Cn1ncc2ccc(CC(=O)Nc3cnn(Cc4ccc(OC(F)(F)F)c(F)c4)n3)cc12 Show InChI InChI=1S/C20H16F4N6O2/c1-29-16-7-12(2-4-14(16)9-25-29)8-19(31)27-18-10-26-30(28-18)11-13-3-5-17(15(21)6-13)32-20(22,23)24/h2-7,9-10H,8,11H2,1H3,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372632 (2-[6-(3,3-Difluoro-pyrrolidin-1-yl)-pyridin-3-yl]-...) Show SMILES Fc1cc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)ccc1OC(F)(F)F Show InChI InChI=1S/C21H18F6N6O2/c22-15-7-14(1-3-16(15)35-21(25,26)27)11-33-29-10-17(31-33)30-19(34)8-13-2-4-18(28-9-13)32-6-5-20(23,24)12-32/h1-4,7,9-10H,5-6,8,11-12H2,(H,30,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372476 (2-(1-Butyl-1H-indazol-5-yl)-N-[2-(3,4-difluoro-ben...) Show SMILES CCCCn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C22H22F2N6O/c1-2-3-8-29-20-7-5-15(9-17(20)12-25-29)11-22(31)27-21-13-26-30(28-21)14-16-4-6-18(23)19(24)10-16/h4-7,9-10,12-13H,2-3,8,11,14H2,1H3,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372450 (2-(4-Dimethylamino-phenyl)-N-[2-(4-fluoro-benzyl)-...) Show SMILES CN(C)c1ccc(CC(=O)Nc2cnn(Cc3ccc(F)cc3)n2)cc1 Show InChI InChI=1S/C19H20FN5O/c1-24(2)17-9-5-14(6-10-17)11-19(26)22-18-12-21-25(23-18)13-15-3-7-16(20)8-4-15/h3-10,12H,11,13H2,1-2H3,(H,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372460 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(cc3)C3(F)COC3)n2)cc1F Show InChI InChI=1S/C20H17F3N4O2/c21-16-6-3-14(7-17(16)22)10-27-24-9-18(26-27)25-19(28)8-13-1-4-15(5-2-13)20(23)11-29-12-20/h1-7,9H,8,10-12H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372645 (N-[2-(4-Cyano-3-fluoro-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1cc(CC(=O)Nc2cnn(Cc3ccc(C#N)c(F)c3)n2)ccc1OCC(F)(F)F Show InChI InChI=1S/C21H17F4N5O2/c1-13-6-14(3-5-18(13)32-12-21(23,24)25)8-20(31)28-19-10-27-30(29-19)11-15-2-4-16(9-26)17(22)7-15/h2-7,10H,8,11-12H2,1H3,(H,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372605 (N-[2-(4-Cyano-3-methyl-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES CC(C)c1ccc(CC(=O)Nc2cnn(Cc3ccc(C#N)c(C)c3)n2)cc1 Show InChI InChI=1S/C22H23N5O/c1-15(2)19-7-4-17(5-8-19)11-22(28)25-21-13-24-27(26-21)14-18-6-9-20(12-23)16(3)10-18/h4-10,13,15H,11,14H2,1-3H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372514 (N-[2-(4-Cyano-3-fluoro-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cn1ccc2cc(CC(=O)Nc3cnn(Cc4ccc(C#N)c(F)c4)n3)ccc12 Show InChI InChI=1S/C21H17FN6O/c1-27-7-6-16-8-14(3-5-19(16)27)10-21(29)25-20-12-24-28(26-20)13-15-2-4-17(11-23)18(22)9-15/h2-9,12H,10,13H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372485 (2-[6-(3,3-Difluoro-pyrrolidin-1-yl)-pyridin-3-yl]-...) Show SMILES CCOc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1 Show InChI InChI=1S/C22H24F2N6O2/c1-2-32-18-6-3-16(4-7-18)14-30-26-13-19(28-30)27-21(31)11-17-5-8-20(25-12-17)29-10-9-22(23,24)15-29/h3-8,12-13H,2,9-11,14-15H2,1H3,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372480 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES CCCn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C21H20F2N6O/c1-2-7-28-19-6-4-14(8-16(19)11-24-28)10-21(30)26-20-12-25-29(27-20)13-15-3-5-17(22)18(23)9-15/h3-6,8-9,11-12H,2,7,10,13H2,1H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372472 (N-[2-(4-Cyano-benzyl)-2H-[1,2,3]triazol-4-yl]-2-(4...) Show SMILES CC(C)c1ccc(CC(=O)Nc2cnn(Cc3ccc(cc3)C#N)n2)cc1 Show InChI InChI=1S/C21H21N5O/c1-15(2)19-9-7-16(8-10-19)11-21(27)24-20-13-23-26(25-20)14-18-5-3-17(12-22)4-6-18/h3-10,13,15H,11,14H2,1-2H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372541 (N-[2-(4-Cyano-benzyl)-2H-[1,2,3]triazol-4-yl]-2-(1...) Show SMILES Cn1ccc2cc(CC(=O)Nc3cnn(Cc4ccc(cc4)C#N)n3)ccc12 Show InChI InChI=1S/C21H18N6O/c1-26-9-8-18-10-17(6-7-19(18)26)11-21(28)24-20-13-23-27(25-20)14-16-4-2-15(12-22)3-5-16/h2-10,13H,11,14H2,1H3,(H,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372547 (N-[2-(4-Cyano-3-fluoro-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1cn(C)c2cc(CC(=O)Nc3cnn(Cc4ccc(C#N)c(F)c4)n3)ccc12 Show InChI InChI=1S/C22H19FN6O/c1-14-12-28(2)20-8-15(4-6-18(14)20)9-22(30)26-21-11-25-29(27-21)13-16-3-5-17(10-24)19(23)7-16/h3-8,11-12H,9,13H2,1-2H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372513 (N-[2-(4-Methyl-benzyl)-2H-[1,2,3]triazol-4-yl]-2-(...) Show SMILES Cc1ccc(Cn2ncc(NC(=O)Cc3ccc4n(C)ncc4c3)n2)cc1 Show InChI InChI=1S/C20H20N6O/c1-14-3-5-15(6-4-14)13-26-22-12-19(24-26)23-20(27)10-16-7-8-18-17(9-16)11-21-25(18)2/h3-9,11-12H,10,13H2,1-2H3,(H,23,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372531 (N-[2-(4-Difluoromethoxy-benzyl)-2H-[1,2,3]triazol-...) Show SMILES Cn1ccc2cc(CC(=O)Nc3cnn(Cc4ccc(OC(F)F)cc4)n3)ccc12 Show InChI InChI=1S/C21H19F2N5O2/c1-27-9-8-16-10-15(4-7-18(16)27)11-20(29)25-19-12-24-28(26-19)13-14-2-5-17(6-3-14)30-21(22)23/h2-10,12,21H,11,13H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372434 (N-[2-(4-Fluoro-benzyl)-2H-[1,2,3]triazol4-yl]-2-(4...) Show SMILES CC(C)c1ccc(CC(=O)Nc2cnn(Cc3ccc(F)cc3)n2)cc1 Show InChI InChI=1S/C20H21FN4O/c1-14(2)17-7-3-15(4-8-17)11-20(26)23-19-12-22-25(24-19)13-16-5-9-18(21)10-6-16/h3-10,12,14H,11,13H2,1-2H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372542 (N-[2-(4-Cyano-benzyl)-2H-[1,2,3]triazol4-yl]-2-(1,...) Show SMILES Cc1cn(C)c2ccc(CC(=O)Nc3cnn(Cc4ccc(cc4)C#N)n3)cc12 Show InChI InChI=1S/C22H20N6O/c1-15-13-27(2)20-8-7-18(9-19(15)20)10-22(29)25-21-12-24-28(26-21)14-17-5-3-16(11-23)4-6-17/h3-9,12-13H,10,14H2,1-2H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372607 (N-[2-(4-Cyano-3-methyl-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1cc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)ccc1C#N Show InChI InChI=1S/C22H21F2N7O/c1-15-8-17(2-4-18(15)10-25)13-31-27-12-19(29-31)28-21(32)9-16-3-5-20(26-11-16)30-7-6-22(23,24)14-30/h2-5,8,11-12H,6-7,9,13-14H2,1H3,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372474 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Cc1nn(C)c2ccc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)cc12 Show InChI InChI=1S/C20H18F2N6O/c1-12-15-7-13(4-6-18(15)27(2)25-12)9-20(29)24-19-10-23-28(26-19)11-14-3-5-16(21)17(22)8-14/h3-8,10H,9,11H2,1-2H3,(H,24,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372619 (N-[2-(4-Difluoromethoxy-3-fluoro-benzyl)-2H-[1,2,3...) Show SMILES Cn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(OC(F)F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C20H17F3N6O2/c1-28-16-4-2-12(6-14(16)9-24-28)8-19(30)26-18-10-25-29(27-18)11-13-3-5-17(15(21)7-13)31-20(22)23/h2-7,9-10,20H,8,11H2,1H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372455 (2-(4-Cyclobutoxy-phenyl)-N-[2-(3,4-difluoro-benzyl...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(OC4CCC4)cc3)n2)cc1F Show InChI InChI=1S/C21H20F2N4O2/c22-18-9-6-15(10-19(18)23)13-27-24-12-20(26-27)25-21(28)11-14-4-7-17(8-5-14)29-16-2-1-3-16/h4-10,12,16H,1-3,11,13H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372611 (N-[2-(4-Cyano-3-methyl-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cc1cn(C)c2ccc(CC(=O)Nc3cnn(Cc4ccc(C#N)c(C)c4)n3)cc12 Show InChI InChI=1S/C23H22N6O/c1-15-8-18(4-6-19(15)11-24)14-29-25-12-22(27-29)26-23(30)10-17-5-7-21-20(9-17)16(2)13-28(21)3/h4-9,12-13H,10,14H2,1-3H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372527 (N-[2-(3,5-Difluoro-4-methoxy-benzyl)-2H-[1,2,3]tri...) Show SMILES COc1c(F)cc(Cn2ncc(NC(=O)Cc3ccc4n(C)ncc4c3)n2)cc1F Show InChI InChI=1S/C20H18F2N6O2/c1-27-17-4-3-12(5-14(17)9-23-27)8-19(29)25-18-10-24-28(26-18)11-13-6-15(21)20(30-2)16(22)7-13/h3-7,9-10H,8,11H2,1-2H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372509 (2-[6-(3,3-Difluoro-pyrrolidin-1-yl)-pyridin-3-yl]-...) Show SMILES Cc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1 Show InChI InChI=1S/C21H22F2N6O/c1-15-2-4-16(5-3-15)13-29-25-12-18(27-29)26-20(30)10-17-6-7-19(24-11-17)28-9-8-21(22,23)14-28/h2-7,11-12H,8-10,13-14H2,1H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372456 (2-(4-Cyclopropoxy-phenyl)-N-[2-(3,4-difluoro-benzy...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(OC4CC4)cc3)n2)cc1F Show InChI InChI=1S/C20H18F2N4O2/c21-17-8-3-14(9-18(17)22)12-26-23-11-19(25-26)24-20(27)10-13-1-4-15(5-2-13)28-16-6-7-16/h1-5,8-9,11,16H,6-7,10,12H2,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372638 (N-[2-(3-Fluoro-4-trifluoromethoxy-benzyl)-2H-[1,2,...) Show SMILES Fc1cc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCCC3)n2)ccc1OC(F)(F)F Show InChI InChI=1S/C21H20F4N6O2/c22-16-9-15(3-5-17(16)33-21(23,24)25)13-31-27-12-18(29-31)28-20(32)10-14-4-6-19(26-11-14)30-7-1-2-8-30/h3-6,9,11-12H,1-2,7-8,10,13H2,(H,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372479 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES CC(C)n1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc12 Show InChI InChI=1S/C21H20F2N6O/c1-13(2)29-19-6-4-14(7-16(19)10-25-29)9-21(30)26-20-11-24-28(27-20)12-15-3-5-17(22)18(23)8-15/h3-8,10-11,13H,9,12H2,1-2H3,(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372684 (N-[2-(4-Cyano-benzyl)-2H-[1,2,3]triazol-4-yl]-2-[4...) Show SMILES FC1(F)CC(COc2ccc(CC(=O)Nc3cnn(Cc4ccc(cc4)C#N)n3)cc2)C1 Show InChI InChI=1S/C23H21F2N5O2/c24-23(25)10-19(11-23)15-32-20-7-5-16(6-8-20)9-22(31)28-21-13-27-30(29-21)14-18-3-1-17(12-26)2-4-18/h1-8,13,19H,9-11,14-15H2,(H,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair

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