Found 30 hits with Last Name = 'bouazzaoui' and Initial = 's' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Legumain
(Homo sapiens (Human)) | BDBM50015362
(CHEMBL3264590)Show SMILES CCOc1cccc(c1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C25H28N4O5/c1-2-33-21-6-3-5-19(13-21)18-10-8-17(9-11-18)16-34-25(32)29-12-4-7-22(29)24(31)28-20(15-26)14-23(27)30/h3,5-6,8-11,13,20,22H,2,4,7,12,14,16H2,1H3,(H2,27,30)(H,28,31)/t20-,22-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015361
(CHEMBL3264589)Show SMILES COc1cccc(c1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C24H26N4O5/c1-32-20-5-2-4-18(12-20)17-9-7-16(8-10-17)15-33-24(31)28-11-3-6-21(28)23(30)27-19(14-25)13-22(26)29/h2,4-5,7-10,12,19,21H,3,6,11,13,15H2,1H3,(H2,26,29)(H,27,30)/t19-,21-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015348
(CHEMBL3264578)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccc(F)cc1)C#N |r| Show InChI InChI=1S/C23H23FN4O4/c24-18-9-7-17(8-10-18)16-5-3-15(4-6-16)14-32-23(31)28-11-1-2-20(28)22(30)27-19(13-25)12-21(26)29/h3-10,19-20H,1-2,11-12,14H2,(H2,26,29)(H,27,30)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015363
(CHEMBL3264591)Show SMILES CC(C)Oc1cccc(c1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C26H30N4O5/c1-17(2)35-22-6-3-5-20(13-22)19-10-8-18(9-11-19)16-34-26(33)30-12-4-7-23(30)25(32)29-21(15-27)14-24(28)31/h3,5-6,8-11,13,17,21,23H,4,7,12,14,16H2,1-2H3,(H2,28,31)(H,29,32)/t21-,23-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015365
(CHEMBL3264593)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccc(Cl)nc1)C#N |r| Show InChI InChI=1S/C22H22ClN5O4/c23-19-8-7-16(12-26-19)15-5-3-14(4-6-15)13-32-22(31)28-9-1-2-18(28)21(30)27-17(11-24)10-20(25)29/h3-8,12,17-18H,1-2,9-10,13H2,(H2,25,29)(H,27,30)/t17-,18-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015353
(CHEMBL3264583)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1cccc(Cl)c1)C#N |r| Show InChI InChI=1S/C23H23ClN4O4/c24-18-4-1-3-17(11-18)16-8-6-15(7-9-16)14-32-23(31)28-10-2-5-20(28)22(30)27-19(13-25)12-21(26)29/h1,3-4,6-9,11,19-20H,2,5,10,12,14H2,(H2,26,29)(H,27,30)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015351
(CHEMBL3264581)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccc(F)c(F)c1)C#N |r| Show InChI InChI=1S/C23H22F2N4O4/c24-18-8-7-16(10-19(18)25)15-5-3-14(4-6-15)13-33-23(32)29-9-1-2-20(29)22(31)28-17(12-26)11-21(27)30/h3-8,10,17,20H,1-2,9,11,13H2,(H2,27,30)(H,28,31)/t17-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015359
(CHEMBL3264587)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccc(cc1)C(F)(F)F)C#N |r| Show InChI InChI=1S/C24H23F3N4O4/c25-24(26,27)18-9-7-17(8-10-18)16-5-3-15(4-6-16)14-35-23(34)31-11-1-2-20(31)22(33)30-19(13-28)12-21(29)32/h3-10,19-20H,1-2,11-12,14H2,(H2,29,32)(H,30,33)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015339
(CHEMBL3264272)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccccc1)C#N |r| Show InChI InChI=1S/C23H24N4O4/c24-14-19(13-21(25)28)26-22(29)20-7-4-12-27(20)23(30)31-15-16-8-10-18(11-9-16)17-5-2-1-3-6-17/h1-3,5-6,8-11,19-20H,4,7,12-13,15H2,(H2,25,28)(H,26,29)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015341
(CHEMBL3264274)Show SMILES Cc1ccc(cc1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C24H26N4O4/c1-16-4-8-18(9-5-16)19-10-6-17(7-11-19)15-32-24(31)28-12-2-3-21(28)23(30)27-20(14-25)13-22(26)29/h4-11,20-21H,2-3,12-13,15H2,1H3,(H2,26,29)(H,27,30)/t20-,21-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015350
(CHEMBL3264580)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1cccc(F)c1F)C#N |r| Show InChI InChI=1S/C23H22F2N4O4/c24-18-4-1-3-17(21(18)25)15-8-6-14(7-9-15)13-33-23(32)29-10-2-5-19(29)22(31)28-16(12-26)11-20(27)30/h1,3-4,6-9,16,19H,2,5,10-11,13H2,(H2,27,30)(H,28,31)/t16-,19-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015360
(CHEMBL3264588)Show SMILES COc1ccc(cc1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C24H26N4O5/c1-32-20-10-8-18(9-11-20)17-6-4-16(5-7-17)15-33-24(31)28-12-2-3-21(28)23(30)27-19(14-25)13-22(26)29/h4-11,19,21H,2-3,12-13,15H2,1H3,(H2,26,29)(H,27,30)/t19-,21-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015352
(CHEMBL3264582)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccc(F)cc1F)C#N |r| Show InChI InChI=1S/C23H22F2N4O4/c24-16-7-8-18(19(25)10-16)15-5-3-14(4-6-15)13-33-23(32)29-9-1-2-20(29)22(31)28-17(12-26)11-21(27)30/h3-8,10,17,20H,1-2,9,11,13H2,(H2,27,30)(H,28,31)/t17-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015340
(CHEMBL3264273)Show SMILES Cc1cccc(c1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C24H26N4O4/c1-16-4-2-5-19(12-16)18-9-7-17(8-10-18)15-32-24(31)28-11-3-6-21(28)23(30)27-20(14-25)13-22(26)29/h2,4-5,7-10,12,20-21H,3,6,11,13,15H2,1H3,(H2,26,29)(H,27,30)/t20-,21-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015343
(CHEMBL3264276)Show SMILES CC(C)c1cccc(c1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C26H30N4O4/c1-17(2)20-5-3-6-21(13-20)19-10-8-18(9-11-19)16-34-26(33)30-12-4-7-23(30)25(32)29-22(15-27)14-24(28)31/h3,5-6,8-11,13,17,22-23H,4,7,12,14,16H2,1-2H3,(H2,28,31)(H,29,32)/t22-,23-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015347
(CHEMBL3264577)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1cccc(F)c1)C#N |r| Show InChI InChI=1S/C23H23FN4O4/c24-18-4-1-3-17(11-18)16-8-6-15(7-9-16)14-32-23(31)28-10-2-5-20(28)22(30)27-19(13-25)12-21(26)29/h1,3-4,6-9,11,19-20H,2,5,10,12,14H2,(H2,26,29)(H,27,30)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015356
(CHEMBL3264586)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C#N |r| Show InChI InChI=1S/C24H23F3N4O4/c25-24(26,27)18-4-1-3-17(11-18)16-8-6-15(7-9-16)14-35-23(34)31-10-2-5-20(31)22(33)30-19(13-28)12-21(29)32/h1,3-4,6-9,11,19-20H,2,5,10,12,14H2,(H2,29,32)(H,30,33)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015349
(CHEMBL3264579)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1cc(F)cc(F)c1)C#N |r| Show InChI InChI=1S/C23H22F2N4O4/c24-17-8-16(9-18(25)10-17)15-5-3-14(4-6-15)13-33-23(32)29-7-1-2-20(29)22(31)28-19(12-26)11-21(27)30/h3-6,8-10,19-20H,1-2,7,11,13H2,(H2,27,30)(H,28,31)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015345
(CHEMBL3264278)Show SMILES CC(C)(C)c1cccc(c1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C27H32N4O4/c1-27(2,3)21-7-4-6-20(14-21)19-11-9-18(10-12-19)17-35-26(34)31-13-5-8-23(31)25(33)30-22(16-28)15-24(29)32/h4,6-7,9-12,14,22-23H,5,8,13,15,17H2,1-3H3,(H2,29,32)(H,30,33)/t22-,23-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015344
(CHEMBL3264277)Show SMILES CC(C)c1ccc(cc1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C26H30N4O4/c1-17(2)19-9-11-21(12-10-19)20-7-5-18(6-8-20)16-34-26(33)30-13-3-4-23(30)25(32)29-22(15-27)14-24(28)31/h5-12,17,22-23H,3-4,13-14,16H2,1-2H3,(H2,28,31)(H,29,32)/t22-,23-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015336
(CHEMBL3264268)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1cccc(Br)c1)C#N |r| Show InChI InChI=1S/C17H19BrN4O4/c18-12-4-1-3-11(7-12)10-26-17(25)22-6-2-5-14(22)16(24)21-13(9-19)8-15(20)23/h1,3-4,7,13-14H,2,5-6,8,10H2,(H2,20,23)(H,21,24)/t13-,14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015354
(CHEMBL3264584)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccc(Cl)cc1)C#N |r| Show InChI InChI=1S/C23H23ClN4O4/c24-18-9-7-17(8-10-18)16-5-3-15(4-6-16)14-32-23(31)28-11-1-2-20(28)22(30)27-19(13-25)12-21(26)29/h3-10,19-20H,1-2,11-12,14H2,(H2,26,29)(H,27,30)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015338
(CHEMBL3264271)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1cccc(c1)-c1ccccc1)C#N |r| Show InChI InChI=1S/C23H24N4O4/c24-14-19(13-21(25)28)26-22(29)20-10-5-11-27(20)23(30)31-15-16-6-4-9-18(12-16)17-7-2-1-3-8-17/h1-4,6-9,12,19-20H,5,10-11,13,15H2,(H2,25,28)(H,26,29)/t19-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015334
(CHEMBL3264594)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)C#N |r| Show InChI InChI=1S/C17H20N4O4/c18-10-13(9-15(19)22)20-16(23)14-7-4-8-21(14)17(24)25-11-12-5-2-1-3-6-12/h1-3,5-6,13-14H,4,7-9,11H2,(H2,19,22)(H,20,23)/t13-,14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015342
(CHEMBL3264275)Show SMILES CCc1ccc(cc1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C25H28N4O4/c1-2-17-5-9-19(10-6-17)20-11-7-18(8-12-20)16-33-25(32)29-13-3-4-22(29)24(31)28-21(15-26)14-23(27)30/h5-12,21-22H,2-4,13-14,16H2,1H3,(H2,27,30)(H,28,31)/t21-,22-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 169 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015335
(CHEMBL3264267)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1Br)C#N |r| Show InChI InChI=1S/C17H19BrN4O4/c18-13-5-2-1-4-11(13)10-26-17(25)22-7-3-6-14(22)16(24)21-12(9-19)8-15(20)23/h1-2,4-5,12,14H,3,6-8,10H2,(H2,20,23)(H,21,24)/t12-,14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015337
(CHEMBL3264269)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(Br)cc1)C#N |r| Show InChI InChI=1S/C17H19BrN4O4/c18-12-5-3-11(4-6-12)10-26-17(25)22-7-1-2-14(22)16(24)21-13(9-19)8-15(20)23/h3-6,13-14H,1-2,7-8,10H2,(H2,20,23)(H,21,24)/t13-,14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 282 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015364
(CHEMBL3264592)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1cncc(Cl)c1)C#N |r| Show InChI InChI=1S/C22H22ClN5O4/c23-17-8-16(11-26-12-17)15-5-3-14(4-6-15)13-32-22(31)28-7-1-2-19(28)21(30)27-18(10-24)9-20(25)29/h3-6,8,11-12,18-19H,1-2,7,9,13H2,(H2,25,29)(H,27,30)/t18-,19-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 343 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015346
(CHEMBL3264576)Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(COC(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C#N)cc1 |r| Show InChI InChI=1S/C27H32N4O4/c1-27(2,3)21-12-10-20(11-13-21)19-8-6-18(7-9-19)17-35-26(34)31-14-4-5-23(31)25(33)30-22(16-28)15-24(29)32/h6-13,22-23H,4-5,14-15,17H2,1-3H3,(H2,29,32)(H,30,33)/t22-,23-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 348 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |
Legumain
(Homo sapiens (Human)) | BDBM50015355
(CHEMBL3264585)Show SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccc(cc1)-c1ccccc1C(F)(F)F)C#N |r| Show InChI InChI=1S/C24H23F3N4O4/c25-24(26,27)19-5-2-1-4-18(19)16-9-7-15(8-10-16)14-35-23(34)31-11-3-6-20(31)22(33)30-17(13-28)12-21(29)32/h1-2,4-5,7-10,17,20H,3,6,11-12,14H2,(H2,29,32)(H,30,33)/t17-,20-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast
Curated by ChEMBL
| Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrate |
Bioorg Med Chem Lett 24: 2521-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.002 BindingDB Entry DOI: 10.7270/Q2QC052W |
More data for this Ligand-Target Pair | |