Found 136 hits with Last Name = 'brown' and Initial = 'sm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402675
(CHEMBL2207348)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cnccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(14-20)16-29-10-12-30(13-11-29)24(31)27-23-21-8-9-26-15-22(21)33-28-23/h1-9,14-15H,10-13,16H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402675
(CHEMBL2207348)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cnccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(14-20)16-29-10-12-30(13-11-29)24(31)27-23-21-8-9-26-15-22(21)33-28-23/h1-9,14-15H,10-13,16H2,(H,27,28,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50394620
(CHEMBL2164602)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C23H23ClN4O2/c24-19-6-8-21(9-7-19)30-22-5-1-3-18(15-22)17-27-11-13-28(14-12-27)23(29)26-20-4-2-10-25-16-20/h1-10,15-16H,11-14,17H2,(H,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402695
(CHEMBL2207356)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-4-1-3-19(17-22)18-29-13-15-30(16-14-29)25(32)28-24-6-2-5-23-27-11-12-31(23)24/h1-12,17H,13-16,18H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402692
(CHEMBL2207358)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccnc4nccn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(16-21)17-29-12-14-30(15-13-29)24(32)28-22-8-9-26-23-27-10-11-31(22)23/h1-11,16H,12-15,17H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402679
(CHEMBL2207344)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4[nH]ccc4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-6-22(7-5-20)33-23-3-1-2-18(14-23)17-30-10-12-31(13-11-30)25(32)29-21-15-19-8-9-27-24(19)28-16-21/h1-9,14-16H,10-13,17H2,(H,27,28)(H,29,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402694
(CHEMBL2203328)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4cccnn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-6-8-20(9-7-19)33-21-4-1-3-18(15-21)17-29-11-13-30(14-12-29)24(32)28-23-16-26-22-5-2-10-27-31(22)23/h1-10,15-16H,11-14,17H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402685
(CHEMBL2207365)Show SMILES Clc1conc1NC(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 Show InChI InChI=1S/C21H20Cl2N4O3/c22-16-4-6-17(7-5-16)30-18-3-1-2-15(12-18)13-26-8-10-27(11-9-26)21(28)24-20-19(23)14-29-25-20/h1-7,12,14H,8-11,13H2,(H,24,25,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447674
(CHEMBL3112940)Show SMILES Clc1ccc(Oc2cccc(CN3CC4(C3)CCN(CC4)C(=O)Nc3noc4ccccc34)c2)cc1 Show InChI InChI=1S/C28H27ClN4O3/c29-21-8-10-22(11-9-21)35-23-5-3-4-20(16-23)17-32-18-28(19-32)12-14-33(15-13-28)27(34)30-26-24-6-1-2-7-25(24)36-31-26/h1-11,16H,12-15,17-19H2,(H,30,31,34) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402695
(CHEMBL2207356)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-4-1-3-19(17-22)18-29-13-15-30(16-14-29)25(32)28-24-6-2-5-23-27-11-12-31(23)24/h1-12,17H,13-16,18H2,(H,28,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402683
(CHEMBL2207340)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nsnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O2S/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50394629
(CHEMBL2164596 | US9169224, 60)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-9-11-22(12-10-20)30-23-8-4-5-19(17-23)18-27-13-15-28(16-14-27)24(29)26-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2,(H,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402680
(CHEMBL2207343)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cncc4ccccc34)c2)cc1 Show InChI InChI=1S/C27H25ClN4O2/c28-22-8-10-23(11-9-22)34-24-6-3-4-20(16-24)19-31-12-14-32(15-13-31)27(33)30-26-18-29-17-21-5-1-2-7-25(21)26/h1-11,16-18H,12-15,19H2,(H,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402689
(CHEMBL2207361)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnn3)c2)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-18-6-8-19(9-7-18)30-20-4-1-3-17(15-20)16-27-11-13-28(14-12-27)22(29)25-21-5-2-10-24-26-21/h1-10,15H,11-14,16H2,(H,25,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402681
(CHEMBL2207342)Show SMILES Cc1nc2cc(NC(=O)N3CCN(Cc4cccc(Oc5ccc(Cl)cc5)c4)CC3)ccc2o1 Show InChI InChI=1S/C26H25ClN4O3/c1-18-28-24-16-21(7-10-25(24)33-18)29-26(32)31-13-11-30(12-14-31)17-19-3-2-4-23(15-19)34-22-8-5-20(27)6-9-22/h2-10,15-16H,11-14,17H2,1H3,(H,29,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50447654
(CHEMBL3112760)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnccc4Cl)CC3)c2)cc1 Show InChI InChI=1S/C26H26Cl2N4O2/c27-20-4-6-21(7-5-20)34-22-3-1-2-19(14-22)16-31-12-9-26(10-13-31)17-32(18-26)25(33)30-24-15-29-11-8-23(24)28/h1-8,11,14-15H,9-10,12-13,16-18H2,(H,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402677
(CHEMBL2207346)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ccccc34)c2)cc1 Show InChI InChI=1S/C25H23ClN4O3/c26-19-8-10-20(11-9-19)32-21-5-3-4-18(16-21)17-29-12-14-30(15-13-29)25(31)27-24-22-6-1-2-7-23(22)33-28-24/h1-11,16H,12-15,17H2,(H,27,28,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402680
(CHEMBL2207343)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cncc4ccccc34)c2)cc1 Show InChI InChI=1S/C27H25ClN4O2/c28-22-8-10-23(11-9-22)34-24-6-3-4-20(16-24)19-31-12-14-32(15-13-31)27(33)30-26-18-29-17-21-5-1-2-7-25(21)26/h1-11,16-18H,12-15,19H2,(H,30,33) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402690
(CHEMBL2207360)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnccn3)c2)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-18-4-6-19(7-5-18)30-20-3-1-2-17(14-20)16-27-10-12-28(13-11-27)22(29)26-21-15-24-8-9-25-21/h1-9,14-15H,10-13,16H2,(H,25,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447654
(CHEMBL3112760)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnccc4Cl)CC3)c2)cc1 Show InChI InChI=1S/C26H26Cl2N4O2/c27-20-4-6-21(7-5-20)34-22-3-1-2-19(14-22)16-31-12-9-26(10-13-31)17-32(18-26)25(33)30-24-15-29-11-8-23(24)28/h1-8,11,14-15H,9-10,12-13,16-18H2,(H,30,33) | PDB
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UniProtKB/SwissProt
B.MOAD
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UniChem
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| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402677
(CHEMBL2207346)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ccccc34)c2)cc1 Show InChI InChI=1S/C25H23ClN4O3/c26-19-8-10-20(11-9-19)32-21-5-3-4-18(16-21)17-29-12-14-30(15-13-29)25(31)27-24-22-6-1-2-7-23(22)33-28-24/h1-11,16H,12-15,17H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447667
(CHEMBL3112593)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnc5cccnn45)CC3)c2)cc1 Show InChI InChI=1S/C27H27ClN6O2/c28-21-6-8-22(9-7-21)36-23-4-1-3-20(15-23)17-32-13-10-27(11-14-32)18-33(19-27)26(35)31-25-16-29-24-5-2-12-30-34(24)25/h1-9,12,15-16H,10-11,13-14,17-19H2,(H,31,35) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402673
(CHEMBL2207350)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cccnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-23-22-21(33-28-23)5-2-10-26-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402676
(CHEMBL2207347)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ncccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-22-21-5-2-10-26-23(21)33-28-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447655
(CHEMBL3112759)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnccc4C#N)CC3)c2)cc1 Show InChI InChI=1S/C27H26ClN5O2/c28-22-4-6-23(7-5-22)35-24-3-1-2-20(14-24)17-32-12-9-27(10-13-32)18-33(19-27)26(34)31-25-16-30-11-8-21(25)15-29/h1-8,11,14,16H,9-10,12-13,17-19H2,(H,31,34) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402693
(CHEMBL2207357)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cc4nccn4cn3)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(14-21)16-29-10-12-30(13-11-29)24(32)28-22-15-23-26-8-9-31(23)17-27-22/h1-9,14-15,17H,10-13,16H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50447653
(CHEMBL3112761)Show SMILES Clc1ccc(Oc2cccc(CN3CC4(C3)CN(C4)C(=O)Nc3cnccc3Cl)c2)cc1 Show InChI InChI=1S/C24H22Cl2N4O2/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(10-20)12-29-13-24(14-29)15-30(16-24)23(31)28-22-11-27-9-8-21(22)26/h1-11H,12-16H2,(H,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
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UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447669
(CHEMBL3112945)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4noc5cccnc45)CC3)c2)cc1 Show InChI InChI=1S/C27H26ClN5O3/c28-20-6-8-21(9-7-20)35-22-4-1-3-19(15-22)16-32-13-10-27(11-14-32)17-33(18-27)26(34)30-25-24-23(36-31-25)5-2-12-29-24/h1-9,12,15H,10-11,13-14,16-18H2,(H,30,31,34) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402685
(CHEMBL2207365)Show SMILES Clc1conc1NC(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 Show InChI InChI=1S/C21H20Cl2N4O3/c22-16-4-6-17(7-5-16)30-18-3-1-2-15(12-18)13-26-8-10-27(11-9-26)21(28)24-20-19(23)14-29-25-20/h1-7,12,14H,8-11,13H2,(H,24,25,28) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402679
(CHEMBL2207344)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4[nH]ccc4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-6-22(7-5-20)33-23-3-1-2-18(14-23)17-30-10-12-31(13-11-30)25(32)29-21-15-19-8-9-27-24(19)28-16-21/h1-9,14-16H,10-13,17H2,(H,27,28)(H,29,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402673
(CHEMBL2207350)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cccnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-23-22-21(33-28-23)5-2-10-26-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447670
(CHEMBL3112944)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4noc5ccccc45)CC3)c2)cc1 Show InChI InChI=1S/C28H27ClN4O3/c29-21-8-10-22(11-9-21)35-23-5-3-4-20(16-23)17-32-14-12-28(13-15-32)18-33(19-28)27(34)30-26-24-6-1-2-7-25(24)36-31-26/h1-11,16H,12-15,17-19H2,(H,30,31,34) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402676
(CHEMBL2207347)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ncccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-22-21-5-2-10-26-23(21)33-28-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50447661
(CHEMBL3112952)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnc(nc4)-c4ccccc4)CC3)c2)cc1 Show InChI InChI=1S/C31H30ClN5O2/c32-25-9-11-27(12-10-25)39-28-8-4-5-23(17-28)20-36-15-13-31(14-16-36)21-37(22-31)30(38)35-26-18-33-29(34-19-26)24-6-2-1-3-7-24/h1-12,17-19H,13-16,20-22H2,(H,35,38) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402692
(CHEMBL2207358)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccnc4nccn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(16-21)17-29-12-14-30(15-13-29)24(32)28-22-8-9-26-23-27-10-11-31(22)23/h1-11,16H,12-15,17H2,(H,28,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402683
(CHEMBL2207340)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nsnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O2S/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50447677
(CHEMBL3112775)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)Nc3ccc(nc3)-n3nccn3)c2)cc1 Show InChI InChI=1S/C30H32ClN7O2/c31-24-4-7-26(8-5-24)40-27-3-1-2-23(20-27)22-36-16-10-30(11-17-36)12-18-37(19-13-30)29(39)35-25-6-9-28(32-21-25)38-33-14-15-34-38/h1-9,14-15,20-21H,10-13,16-19,22H2,(H,35,39) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50447686
(CHEMBL3112766)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C28H31ClN4O2/c29-23-6-8-25(9-7-23)35-26-5-1-3-22(19-26)21-32-15-10-28(11-16-32)12-17-33(18-13-28)27(34)31-24-4-2-14-30-20-24/h1-9,14,19-20H,10-13,15-18,21H2,(H,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447668
(CHEMBL3112946)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnc5ccccn45)CC3)c2)cc1 Show InChI InChI=1S/C28H28ClN5O2/c29-22-7-9-23(10-8-22)36-24-5-3-4-21(16-24)18-32-14-11-28(12-15-32)19-33(20-28)27(35)31-26-17-30-25-6-1-2-13-34(25)26/h1-10,13,16-17H,11-12,14-15,18-20H2,(H,31,35) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402684
(CHEMBL2207366)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nonc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402686
(CHEMBL2207364)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccon3)c2)cc1 Show InChI InChI=1S/C21H21ClN4O3/c22-17-4-6-18(7-5-17)29-19-3-1-2-16(14-19)15-25-9-11-26(12-10-25)21(27)23-20-8-13-28-24-20/h1-8,13-14H,9-12,15H2,(H,23,24,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447673
(CHEMBL3112941)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4ccc(nc4)-n4nccn4)CC3)c2)cc1 Show InChI InChI=1S/C28H28ClN7O2/c29-22-4-7-24(8-5-22)38-25-3-1-2-21(16-25)18-34-14-10-28(11-15-34)19-35(20-28)27(37)33-23-6-9-26(30-17-23)36-31-12-13-32-36/h1-9,12-13,16-17H,10-11,14-15,18-20H2,(H,33,37) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447675
(CHEMBL3112939)Show SMILES Clc1ccc(Oc2cccc(CN3CC4(C3)CCN(CC4)C(=O)Nc3ccc(nc3)-n3nccn3)c2)cc1 Show InChI InChI=1S/C28H28ClN7O2/c29-22-4-7-24(8-5-22)38-25-3-1-2-21(16-25)18-34-19-28(20-34)10-14-35(15-11-28)27(37)33-23-6-9-26(30-17-23)36-31-12-13-32-36/h1-9,12-13,16-17H,10-11,14-15,18-20H2,(H,33,37) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50447673
(CHEMBL3112941)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4ccc(nc4)-n4nccn4)CC3)c2)cc1 Show InChI InChI=1S/C28H28ClN7O2/c29-22-4-7-24(8-5-22)38-25-3-1-2-21(16-25)18-34-14-10-28(11-15-34)19-35(20-28)27(37)33-23-6-9-26(30-17-23)36-31-12-13-32-36/h1-9,12-13,16-17H,10-11,14-15,18-20H2,(H,33,37) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402688
(CHEMBL2207362)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccn[nH]3)c2)cc1 Show InChI InChI=1S/C21H22ClN5O2/c22-17-4-6-18(7-5-17)29-19-3-1-2-16(14-19)15-26-10-12-27(13-11-26)21(28)24-20-8-9-23-25-20/h1-9,14H,10-13,15H2,(H2,23,24,25,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402697
(CHEMBL2207354)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccn4ccnc4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-6-22(7-5-20)33-23-3-1-2-19(16-23)18-29-12-14-31(15-13-29)25(32)28-21-8-10-30-11-9-27-24(30)17-21/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50394620
(CHEMBL2164602)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C23H23ClN4O2/c24-19-6-8-21(9-7-19)30-22-5-1-3-18(15-22)17-27-11-13-28(14-12-27)23(29)26-20-4-2-10-25-16-20/h1-10,15-16H,11-14,17H2,(H,26,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447677
(CHEMBL3112775)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)Nc3ccc(nc3)-n3nccn3)c2)cc1 Show InChI InChI=1S/C30H32ClN7O2/c31-24-4-7-26(8-5-24)40-27-3-1-2-23(20-27)22-36-16-10-30(11-17-36)12-18-37(19-13-30)29(39)35-25-6-9-28(32-21-25)38-33-14-15-34-38/h1-9,14-15,20-21H,10-13,16-19,22H2,(H,35,39) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447671
(CHEMBL3112943)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnc5[nH]ccc5c4)CC3)c2)cc1 Show InChI InChI=1S/C28H28ClN5O2/c29-22-4-6-24(7-5-22)36-25-3-1-2-20(14-25)17-33-12-9-28(10-13-33)18-34(19-28)27(35)32-23-15-21-8-11-30-26(21)31-16-23/h1-8,11,14-16H,9-10,12-13,17-19H2,(H,30,31)(H,32,35) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50447661
(CHEMBL3112952)Show SMILES Clc1ccc(Oc2cccc(CN3CCC4(CN(C4)C(=O)Nc4cnc(nc4)-c4ccccc4)CC3)c2)cc1 Show InChI InChI=1S/C31H30ClN5O2/c32-25-9-11-27(12-10-25)39-28-8-4-5-23(17-28)20-36-15-13-31(14-16-36)21-37(22-31)30(38)35-26-18-33-29(34-19-26)24-6-2-1-3-7-24/h1-12,17-19H,13-16,20-22H2,(H,35,38) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C.
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH after 60 mins |
Bioorg Med Chem Lett 24: 737-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.113
BindingDB Entry DOI: 10.7270/Q2CN75DP |
More data for this
Ligand-Target Pair | |
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