Compile Data Set for Download or QSAR

Found 204 hits with Last Name = 'campestre' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	0.600	-52.6	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Stromelysin-1 (Homo sapiens (Human))	BDBM12075 ((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4.40	-47.7	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	5	-47.4	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	40	-42.2	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM12074 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	54.9	-41.4	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50386560 (CHEMBL2048250) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H](N)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H38N6O5/c33-23-18-28(38(19-23)32(43)25(34)15-22-11-13-24(39)14-12-22)31(42)37-27(17-21-9-5-2-6-10-21)30(41)36-26(29(35)40)16-20-7-3-1-4-8-20/h1-14,23,25-28,39H,15-19,33-34H2,(H2,35,40)(H,36,41)(H,37,42)/t23-,25-,26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Chieti-Pescara G. d'Annunzio Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in HN9.10 cells after 3 hrs by scintillation counting				J Med Chem 55: 3027-35 (2012) Article DOI: 10.1021/jm201402v BindingDB Entry DOI: 10.7270/Q2571D38
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50386559 (CHEMBL2048248) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H]2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N2 |r| Show InChI InChI=1S/C32H35N5O5/c33-25(15-22-11-13-24(38)14-12-22)32(42)37-19-23-18-28(37)31(41)36-27(17-21-9-5-2-6-10-21)30(40)35-26(29(39)34-23)16-20-7-3-1-4-8-20/h1-14,23,25-28,38H,15-19,33H2,(H,34,39)(H,35,40)(H,36,41)/t23-,25-,26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Chieti-Pescara G. d'Annunzio Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in HN9.10 cells after 3 hrs by scintillation counting				J Med Chem 55: 3027-35 (2012) Article DOI: 10.1021/jm201402v BindingDB Entry DOI: 10.7270/Q2571D38
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM12073 ((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	700	-35.1	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair				3D Structure (crystal)
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12073 ((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.20E+3	-33.8	n/a	n/a	n/a	n/a	n/a	7.5	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50386561 (CHEMBL2048249) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H](N)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C32H37N5O6/c33-23-18-28(37(19-23)31(41)25(34)15-22-11-13-24(38)14-12-22)30(40)35-26(16-20-7-3-1-4-8-20)29(39)36-27(32(42)43)17-21-9-5-2-6-10-21/h1-14,23,25-28,38H,15-19,33-34H2,(H,35,40)(H,36,39)(H,42,43)/t23-,25-,26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Chieti-Pescara G. d'Annunzio Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in HN9.10 cells after 3 hrs by scintillation counting				J Med Chem 55: 3027-35 (2012) Article DOI: 10.1021/jm201402v BindingDB Entry DOI: 10.7270/Q2571D38
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50031795 ((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C18H27N3O4/c1-12(2)9-14(11-16(22)21-25)17(23)20-15(18(24)19-3)10-13-7-5-4-6-8-13/h4-8,12,14-15,25H,9-11H2,1-3H3,(H,19,24)(H,20,23)(H,21,22)/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	0.0460	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198038 (CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...) Show SMILES CCOc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C18H24NO6PS/c1-4-25-16-9-5-14(6-10-16)15-7-11-17(12-8-15)27(23,24)19-18(13(2)3)26(20,21)22/h5-13,18-19H,4H2,1-3H3,(H2,20,21,22)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50031795 ((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C18H27N3O4/c1-12(2)9-14(11-16(22)21-25)17(23)20-15(18(24)19-3)10-13-7-5-4-6-8-13/h4-8,12,14-15,25H,9-11H2,1-3H3,(H,19,24)(H,20,23)(H,21,22)/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50198038 (CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...) Show SMILES CCOc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C18H24NO6PS/c1-4-25-16-9-5-14(6-10-16)15-7-11-17(12-8-15)27(23,24)19-18(13(2)3)26(20,21)22/h5-13,18-19H,4H2,1-3H3,(H2,20,21,22)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198035 (CHEMBL227501 | [(R)-2-methyl-1-(3'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1cccc(C)c1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-9-7-14(8-10-16)15-6-4-5-13(3)11-15/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50198038 (CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...) Show SMILES CCOc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C18H24NO6PS/c1-4-25-16-9-5-14(6-10-16)15-7-11-17(12-8-15)27(23,24)19-18(13(2)3)26(20,21)22/h5-13,18-19H,4H2,1-3H3,(H2,20,21,22)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50031795 ((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C18H27N3O4/c1-12(2)9-14(11-16(22)21-25)17(23)20-15(18(24)19-3)10-13-7-5-4-6-8-13/h4-8,12,14-15,25H,9-11H2,1-3H3,(H,19,24)(H,20,23)(H,21,22)/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198034 (CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C16H19ClNO5PS/c1-11(2)16(24(19,20)21)18-25(22,23)15-9-5-13(6-10-15)12-3-7-14(17)8-4-12/h3-11,16,18H,1-2H3,(H2,19,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM8485 ((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H20N2O5S/c1-12(2)16(17(20)18-21)19-25(22,23)15-10-8-14(9-11-15)24-13-6-4-3-5-7-13/h3-12,16,19,21H,1-2H3,(H,18,20)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	7.0	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50198038 (CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...) Show SMILES CCOc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C18H24NO6PS/c1-4-25-16-9-5-14(6-10-16)15-7-11-17(12-8-15)27(23,24)19-18(13(2)3)26(20,21)22/h5-13,18-19H,4H2,1-3H3,(H2,20,21,22)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198039 (CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)P(O)(O)=O Show InChI InChI=1S/C16H19FNO5PS/c1-11(2)16(24(19,20)21)18-25(22,23)15-9-5-13(6-10-15)12-3-7-14(17)8-4-12/h3-11,16,18H,1-2H3,(H2,19,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198030 (CHEMBL228188 | [(R)-1-(3'-chloro-biphenyl-4-sulfon...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1cccc(Cl)c1)P(O)(O)=O Show InChI InChI=1S/C16H19ClNO5PS/c1-11(2)16(24(19,20)21)18-25(22,23)15-8-6-12(7-9-15)13-4-3-5-14(17)10-13/h3-11,16,18H,1-2H3,(H2,19,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
Neutrophil collagenase (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (crystal)
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198031 (CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...) Show SMILES CC(C)Oc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C19H26NO6PS/c1-13(2)19(27(21,22)23)20-28(24,25)18-11-7-16(8-12-18)15-5-9-17(10-6-15)26-14(3)4/h5-14,19-20H,1-4H3,(H2,21,22,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50198031 (CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...) Show SMILES CC(C)Oc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C19H26NO6PS/c1-13(2)19(27(21,22)23)20-28(24,25)18-11-7-16(8-12-18)15-5-9-17(10-6-15)26-14(3)4/h5-14,19-20H,1-4H3,(H2,21,22,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198040 (CHEMBL389898 | [(R)-2-methyl-1-(4'-pyrrolidin-1-yl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)N1CCCC1)P(O)(O)=O Show InChI InChI=1S/C20H27N2O5PS/c1-15(2)20(28(23,24)25)21-29(26,27)19-11-7-17(8-12-19)16-5-9-18(10-6-16)22-13-3-4-14-22/h5-12,15,20-21H,3-4,13-14H2,1-2H3,(H2,23,24,25)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50198037 (CHEMBL228187 | [(R)-1-(3'-fluoro-biphenyl-4-sulfon...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1cccc(F)c1)P(O)(O)=O Show InChI InChI=1S/C16H19FNO5PS/c1-11(2)16(24(19,20)21)18-25(22,23)15-8-6-12(7-9-15)13-4-3-5-14(17)10-13/h3-11,16,18H,1-2H3,(H2,19,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair				3D Structure (docked)
Collagenase 3 (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12076 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H19BrN2O4S/c1-11(2)16(17(21)19-22)20-25(23,24)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,20,22H,1-2H3,(H,19,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.0	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM8485 ((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H20N2O5S/c1-12(2)16(17(20)18-21)19-25(22,23)15-10-8-14(9-11-15)24-13-6-4-3-5-7-13/h3-12,16,19,21H,1-2H3,(H,18,20)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	6.0	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12075 ((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	7.0	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50198033 (CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O Show InChI InChI=1S/C17H22NO5PS/c1-12(2)17(24(19,20)21)18-25(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50198031 (CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...) Show SMILES CC(C)Oc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O Show InChI InChI=1S/C19H26NO6PS/c1-13(2)19(27(21,22)23)20-28(24,25)18-11-7-16(8-12-18)15-5-9-17(10-6-15)26-14(3)4/h5-14,19-20H,1-4H3,(H2,21,22,23)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12074 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50198040 (CHEMBL389898 | [(R)-2-methyl-1-(4'-pyrrolidin-1-yl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)N1CCCC1)P(O)(O)=O Show InChI InChI=1S/C20H27N2O5PS/c1-15(2)20(28(23,24)25)21-29(26,27)19-11-7-17(8-12-19)16-5-9-18(10-6-16)22-13-3-4-14-22/h5-12,15,20-21H,3-4,13-14H2,1-2H3,(H2,23,24,25)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50198034 (CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C16H19ClNO5PS/c1-11(2)16(24(19,20)21)18-25(22,23)15-9-5-13(6-10-15)12-3-7-14(17)8-4-12/h3-11,16,18H,1-2H3,(H2,19,20,21)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM12076 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H19BrN2O4S/c1-11(2)16(17(21)19-22)20-25(23,24)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,20,22H,1-2H3,(H,19,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	6.0	25
Istituto di Cristallografia					Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...				J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O |r| Show InChI InChI=1S/C17H22NO6PS/c1-12(2)17(25(19,20)21)18-26(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17-18H,1-3H3,(H2,19,20,21)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50031795 ((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C18H27N3O4/c1-12(2)9-14(11-16(22)21-25)17(23)20-15(18(24)19-3)10-13-7-5-4-6-8-13/h4-8,12,14-15,25H,9-11H2,1-3H3,(H,19,24)(H,20,23)(H,21,22)/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP7				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50198034 (CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C16H19ClNO5PS/c1-11(2)16(24(19,20)21)18-25(22,23)15-9-5-13(6-10-15)12-3-7-14(17)8-4-12/h3-11,16,18H,1-2H3,(H2,19,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084293 ((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C17H18ClNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084301 ((S)-2-(4'-fluoro-biphenyl-4-sulfonylamino)-3-methy...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C17H18FNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084293 ((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C17H18ClNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Università "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells				Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T
					More data for this Ligand-Target Pair

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