Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 8 (Homo sapiens (Human)) | BDBM50004051 (2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8 | Bioorg Med Chem Lett 15: 349-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.093 BindingDB Entry DOI: 10.7270/Q2G161M2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 8 (Homo sapiens (Human)) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8 | Bioorg Med Chem Lett 15: 349-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.093 BindingDB Entry DOI: 10.7270/Q2G161M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Homo sapiens (Human)) | BDBM50157910 ((2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxymeth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Dissociation constant of radiolabeled compound against recombinant human Metabotropic glutamate receptor 8 | Bioorg Med Chem Lett 15: 349-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.093 BindingDB Entry DOI: 10.7270/Q2G161M2 | |||||||||||
More data for this Ligand-Target Pair |