Compile Data Set for Download or QSAR

Found 6 hits with Last Name = 'cryan' and Initial = 'je'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50263384 (6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazo...) Show SMILES Cc1nc2cc(NC(=O)c3ccc(nc3C)-c3ccc(F)cc3)ccc2s1 Show InChI InChI=1S/C21H16FN3OS/c1-12-17(8-9-18(23-12)14-3-5-15(22)6-4-14)21(26)25-16-7-10-20-19(11-16)24-13(2)27-20/h3-11H,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	5.3	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by whole cell patch clamp a...				Bioorg Med Chem Lett 18: 5609-13 (2008) Article DOI: 10.1016/j.bmcl.2008.08.105 BindingDB Entry DOI: 10.7270/Q2PZ58PN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50263384 (6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazo...) Show SMILES Cc1nc2cc(NC(=O)c3ccc(nc3C)-c3ccc(F)cc3)ccc2s1 Show InChI InChI=1S/C21H16FN3OS/c1-12-17(8-9-18(23-12)14-3-5-15(22)6-4-14)21(26)25-16-7-10-20-19(11-16)24-13(2)27-20/h3-11H,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	5.3	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by FLIPR assay				Bioorg Med Chem Lett 18: 5609-13 (2008) Article DOI: 10.1016/j.bmcl.2008.08.105 BindingDB Entry DOI: 10.7270/Q2PZ58PN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50263384 (6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazo...) Show SMILES Cc1nc2cc(NC(=O)c3ccc(nc3C)-c3ccc(F)cc3)ccc2s1 Show InChI InChI=1S/C21H16FN3OS/c1-12-17(8-9-18(23-12)14-3-5-15(22)6-4-14)21(26)25-16-7-10-20-19(11-16)24-13(2)27-20/h3-11H,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium influx by whole cell patch clamp ass...				Bioorg Med Chem Lett 18: 5609-13 (2008) Article DOI: 10.1016/j.bmcl.2008.08.105 BindingDB Entry DOI: 10.7270/Q2PZ58PN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Cavia porcellus)	BDBM50263384 (6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazo...) Show SMILES Cc1nc2cc(NC(=O)c3ccc(nc3C)-c3ccc(F)cc3)ccc2s1 Show InChI InChI=1S/C21H16FN3OS/c1-12-17(8-9-18(23-12)14-3-5-15(22)6-4-14)21(26)25-16-7-10-20-19(11-16)24-13(2)27-20/h3-11H,1-2H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	5.3	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at guinea pig TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by FLIPR assay				Bioorg Med Chem Lett 18: 5609-13 (2008) Article DOI: 10.1016/j.bmcl.2008.08.105 BindingDB Entry DOI: 10.7270/Q2PZ58PN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50263384 (6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazo...) Show SMILES Cc1nc2cc(NC(=O)c3ccc(nc3C)-c3ccc(F)cc3)ccc2s1 Show InChI InChI=1S/C21H16FN3OS/c1-12-17(8-9-18(23-12)14-3-5-15(22)6-4-14)21(26)25-16-7-10-20-19(11-16)24-13(2)27-20/h3-11H,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	5.3	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by FLIPR assay				Bioorg Med Chem Lett 18: 5609-13 (2008) Article DOI: 10.1016/j.bmcl.2008.08.105 BindingDB Entry DOI: 10.7270/Q2PZ58PN
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50263425 (6-(4-fluorophenyl)-2-methyl-N-(quinolin-7-yl)nicot...) Show SMILES Cc1nc(ccc1C(=O)Nc1ccc2cccnc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H16FN3O/c1-14-19(10-11-20(25-14)16-4-7-17(23)8-5-16)22(27)26-18-9-6-15-3-2-12-24-21(15)13-18/h2-13H,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 18: 5609-13 (2008) Article DOI: 10.1016/j.bmcl.2008.08.105 BindingDB Entry DOI: 10.7270/Q2PZ58PN
					More data for this Ligand-Target Pair