Compile Data Set for Download or QSAR

Found 73 hits with Last Name = 'de-peretti' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50517832 (CHEMBL4564985) Show SMILES CC(C)(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H19ClN2O/c1-22(2,26)18-5-3-4-16(12-18)17-8-11-21-24-20(14-25(21)13-17)15-6-9-19(23)10-7-15/h3-14,26H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50517811 (CHEMBL4576867) Show SMILES OCc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClN2O/c21-18-7-4-15(5-8-18)19-12-23-11-17(6-9-20(23)22-19)16-3-1-2-14(10-16)13-24/h1-12,24H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of CYP2C9 (unknown origin)				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50517833 (CHEMBL4472621) Show SMILES O=C(Nc1ccccc1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C19H14N4O/c24-19(21-15-6-2-1-3-7-15)17-13-23-12-14(9-10-18(23)22-17)16-8-4-5-11-20-16/h1-13H,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of CYP2C9 (unknown origin)				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50517833 (CHEMBL4472621) Show SMILES O=C(Nc1ccccc1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C19H14N4O/c24-19(21-15-6-2-1-3-7-15)17-13-23-12-14(9-10-18(23)22-17)16-8-4-5-11-20-16/h1-13H,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50517833 (CHEMBL4472621) Show SMILES O=C(Nc1ccccc1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C19H14N4O/c24-19(21-15-6-2-1-3-7-15)17-13-23-12-14(9-10-18(23)22-17)16-8-4-5-11-20-16/h1-13H,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50517811 (CHEMBL4576867) Show SMILES OCc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClN2O/c21-18-7-4-15(5-8-18)19-12-23-11-17(6-9-20(23)22-19)16-3-1-2-14(10-16)13-24/h1-12,24H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50517811 (CHEMBL4576867) Show SMILES OCc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClN2O/c21-18-7-4-15(5-8-18)19-12-23-11-17(6-9-20(23)22-19)16-3-1-2-14(10-16)13-24/h1-12,24H,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517808 (CHEMBL4465741) Show SMILES COCc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H17ClN2O/c1-25-14-15-3-2-4-17(11-15)18-7-10-21-23-20(13-24(21)12-18)16-5-8-19(22)9-6-16/h2-13H,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517809 (CHEMBL4587411) Show SMILES CCC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H19ClN2O/c1-2-21(26)17-5-3-4-16(12-17)18-8-11-22-24-20(14-25(22)13-18)15-6-9-19(23)10-7-15/h3-14,21,26H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517810 (CHEMBL4579076) Show SMILES Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)n1 Show InChI InChI=1S/C18H12FN5O/c19-15-5-3-6-16(22-15)23-18(25)14-11-24-10-12(7-8-17(24)21-14)13-4-1-2-9-20-13/h1-11H,(H,22,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517811 (CHEMBL4576867) Show SMILES OCc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClN2O/c21-18-7-4-15(5-8-18)19-12-23-11-17(6-9-20(23)22-19)16-3-1-2-14(10-16)13-24/h1-12,24H,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517812 (CHEMBL4454933) Show SMILES O=C(Nc1nncs1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C15H10N6OS/c22-14(19-15-20-17-9-23-15)12-8-21-7-10(4-5-13(21)18-12)11-3-1-2-6-16-11/h1-9H,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517813 (CHEMBL4464547) Show SMILES Fc1cc(F)cc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1 Show InChI InChI=1S/C19H12F2N4O/c20-13-7-14(21)9-15(8-13)23-19(26)17-11-25-10-12(4-5-18(25)24-17)16-3-1-2-6-22-16/h1-11H,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517814 (CHEMBL4461137) Show SMILES CC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H17ClN2O/c1-14(25)16-3-2-4-17(11-16)18-7-10-21-23-20(13-24(21)12-18)15-5-8-19(22)9-6-15/h2-14,25H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	219	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517815 (CHEMBL4559712) Show SMILES CC(O)(CO)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H19ClN2O2/c1-22(27,14-26)18-4-2-3-16(11-18)17-7-10-21-24-20(13-25(21)12-17)15-5-8-19(23)9-6-15/h2-13,26-27H,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517816 (CHEMBL4440984) Show SMILES OC1(CCOCC1)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN2O2/c25-21-7-4-17(5-8-21)22-16-27-15-19(6-9-23(27)26-22)18-2-1-3-20(14-18)24(28)10-12-29-13-11-24/h1-9,14-16,28H,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517817 (CHEMBL4446736) Show SMILES OC1(COC1)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O2/c23-19-7-4-15(5-8-19)20-12-25-11-17(6-9-21(25)24-20)16-2-1-3-18(10-16)22(26)13-27-14-22/h1-12,26H,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	323	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517814 (CHEMBL4461137) Show SMILES CC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H17ClN2O/c1-14(25)16-3-2-4-17(11-16)18-7-10-21-23-20(13-24(21)12-18)15-5-8-19(22)9-6-15/h2-14,25H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517818 (CHEMBL4453694) Show SMILES Cc1ccc(cc1CO)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H17ClN2O/c1-14-2-3-16(10-18(14)13-25)17-6-9-21-23-20(12-24(21)11-17)15-4-7-19(22)8-5-15/h2-12,25H,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517819 (CHEMBL4475176) Show SMILES OCc1c(F)ccc(c1F)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H13ClF2N2O/c21-14-4-1-12(2-5-14)18-10-25-9-13(3-8-19(25)24-18)15-6-7-17(22)16(11-26)20(15)23/h1-10,26H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517820 (CHEMBL4473232) Show SMILES OCc1cccc(c1F)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H14ClFN2O/c21-16-7-4-13(5-8-16)18-11-24-10-14(6-9-19(24)23-18)17-3-1-2-15(12-25)20(17)22/h1-11,25H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517821 (CHEMBL4521080) Show SMILES O=C(Nc1cnoc1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5O2/c22-16(19-12-7-18-23-10-12)14-9-21-8-11(4-5-15(21)20-14)13-3-1-2-6-17-13/h1-10H,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517822 (CHEMBL4450849) Show SMILES O=C(Nc1ccon1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5O2/c22-16(19-14-6-8-23-20-14)13-10-21-9-11(4-5-15(21)18-13)12-3-1-2-7-17-12/h1-10H,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517823 (CHEMBL4435806) Show SMILES O=C(Nc1nccs1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5OS/c22-15(20-16-18-7-8-23-16)13-10-21-9-11(4-5-14(21)19-13)12-3-1-2-6-17-12/h1-10H,(H,18,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517824 (CHEMBL4455780) Show SMILES O=C(Nc1ccccn1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C18H13N5O/c24-18(22-16-6-2-4-10-20-16)15-12-23-11-13(7-8-17(23)21-15)14-5-1-3-9-19-14/h1-12H,(H,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517825 (CHEMBL4473547) Show SMILES O=C(Nc1ccccc1C#N)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C20H13N5O/c21-11-14-5-1-2-7-17(14)24-20(26)18-13-25-12-15(8-9-19(25)23-18)16-6-3-4-10-22-16/h1-10,12-13H,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517826 (CHEMBL4453191) Show SMILES Fc1ccc(F)c(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1 Show InChI InChI=1S/C19H12F2N4O/c20-13-5-6-14(21)16(9-13)24-19(26)17-11-25-10-12(4-7-18(25)23-17)15-3-1-2-8-22-15/h1-11H,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517827 (CHEMBL4528015) Show SMILES Clc1ccccc1NC(=O)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C19H13ClN4O/c20-14-5-1-2-7-16(14)23-19(25)17-12-24-11-13(8-9-18(24)22-17)15-6-3-4-10-21-15/h1-12H,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517811 (CHEMBL4576867) Show SMILES OCc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClN2O/c21-18-7-4-15(5-8-18)19-12-23-11-17(6-9-20(23)22-19)16-3-1-2-14(10-16)13-24/h1-12,24H,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517821 (CHEMBL4521080) Show SMILES O=C(Nc1cnoc1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5O2/c22-16(19-12-7-18-23-10-12)14-9-21-8-11(4-5-15(21)20-14)13-3-1-2-6-17-13/h1-10H,(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517828 (CHEMBL4465777) Show SMILES O=C(Nc1cc[nH]n1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H12N6O/c23-16(20-14-6-8-18-21-14)13-10-22-9-11(4-5-15(22)19-13)12-3-1-2-7-17-12/h1-10H,(H2,18,20,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517822 (CHEMBL4450849) Show SMILES O=C(Nc1ccon1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5O2/c22-16(19-14-6-8-23-20-14)13-10-21-9-11(4-5-15(21)18-13)12-3-1-2-7-17-12/h1-10H,(H,19,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517829 (CHEMBL4542579) Show SMILES O=C(Nc1cccs1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C17H12N4OS/c22-17(20-16-5-3-9-23-16)14-11-21-10-12(6-7-15(21)19-14)13-4-1-2-8-18-13/h1-11H,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517830 (CHEMBL4475835) Show SMILES Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1F Show InChI InChI=1S/C19H12F2N4O/c20-13-4-3-6-15(18(13)21)24-19(26)16-11-25-10-12(7-8-17(25)23-16)14-5-1-2-9-22-14/h1-11H,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517826 (CHEMBL4453191) Show SMILES Fc1ccc(F)c(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1 Show InChI InChI=1S/C19H12F2N4O/c20-13-5-6-14(21)16(9-13)24-19(26)17-11-25-10-12(4-7-18(25)23-17)15-3-1-2-8-22-15/h1-11H,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517831 (CHEMBL4516628) Show SMILES Fc1ccccc1NC(=O)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C19H13FN4O/c20-14-5-1-2-7-16(14)23-19(25)17-12-24-11-13(8-9-18(24)22-17)15-6-3-4-10-21-15/h1-12H,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517827 (CHEMBL4528015) Show SMILES Clc1ccccc1NC(=O)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C19H13ClN4O/c20-14-5-1-2-7-16(14)23-19(25)17-12-24-11-13(8-9-18(24)22-17)15-6-3-4-10-21-15/h1-12H,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517834 (CHEMBL4555274) Show SMILES Cc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H15ClN2/c1-14-3-2-4-16(11-14)17-7-10-20-22-19(13-23(20)12-17)15-5-8-18(21)9-6-15/h2-13H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517835 (CHEMBL4460521) Show SMILES CN(C)Cc1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H20ClN3/c1-25(2)13-16-4-3-5-18(12-16)19-8-11-22-24-21(15-26(22)14-19)17-6-9-20(23)10-7-17/h3-12,14-15H,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517836 (CHEMBL4542143) Show SMILES Clc1ccc(cc1)-c1cn2cc(ccc2n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C24H22ClN3O/c25-22-7-4-19(5-8-22)23-17-28-16-21(6-9-24(28)26-23)20-3-1-2-18(14-20)15-27-10-12-29-13-11-27/h1-9,14,16-17H,10-13,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517837 (CHEMBL4455501) Show SMILES CNC(=O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H16ClN3O/c1-23-21(26)16-4-2-3-15(11-16)17-7-10-20-24-19(13-25(20)12-17)14-5-8-18(22)9-6-14/h2-13H,1H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517838 (CHEMBL4467468) Show SMILES CCN(CC)C(=O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H22ClN3O/c1-3-27(4-2)24(29)19-7-5-6-18(14-19)20-10-13-23-26-22(16-28(23)15-20)17-8-11-21(25)12-9-17/h5-16H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517839 (CHEMBL4443069) Show SMILES CCCCC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN2O/c1-2-3-7-23(28)19-6-4-5-18(14-19)20-10-13-24-26-22(16-27(24)15-20)17-8-11-21(25)12-9-17/h4-6,8-16,23,28H,2-3,7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517840 (CHEMBL4545262) Show SMILES CCCCCC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H25ClN2O/c1-2-3-4-8-24(29)20-7-5-6-19(15-20)21-11-14-25-27-23(17-28(25)16-21)18-9-12-22(26)13-10-18/h5-7,9-17,24,29H,2-4,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517841 (CHEMBL4468421) Show SMILES OC(C1CCCC1)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN2O/c26-22-11-8-17(9-12-22)23-16-28-15-21(10-13-24(28)27-23)19-6-3-7-20(14-19)25(29)18-4-1-2-5-18/h3,6-16,18,25,29H,1-2,4-5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517842 (CHEMBL4547651) Show SMILES OC(c1ccccc1)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H19ClN2O/c27-23-12-9-18(10-13-23)24-17-29-16-22(11-14-25(29)28-24)20-7-4-8-21(15-20)26(30)19-5-2-1-3-6-19/h1-17,26,30H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517814 (CHEMBL4461137) Show SMILES CC(O)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H17ClN2O/c1-14(25)16-3-2-4-17(11-16)18-7-10-21-23-20(13-24(21)12-18)15-5-8-19(22)9-6-15/h2-14,25H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	219	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517810 (CHEMBL4579076) Show SMILES Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)n1 Show InChI InChI=1S/C18H12FN5O/c19-15-5-3-6-16(22-15)23-18(25)14-11-24-10-12(7-8-17(24)21-14)13-4-1-2-9-20-13/h1-11H,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517830 (CHEMBL4475835) Show SMILES Fc1cccc(NC(=O)c2cn3cc(ccc3n2)-c2ccccn2)c1F Show InChI InChI=1S/C19H12F2N4O/c20-13-4-3-6-15(18(13)21)24-19(26)16-11-25-10-12(7-8-17(25)23-16)14-5-1-2-9-22-14/h1-11H,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 4 group A member 2 (Mus musculus)	BDBM50517812 (CHEMBL4454933) Show SMILES O=C(Nc1nncs1)c1cn2cc(ccc2n1)-c1ccccn1 Show InChI InChI=1S/C15H10N6OS/c22-14(19-15-20-17-9-23-15)12-8-21-7-10(4-5-13(21)18-12)11-3-1-2-6-16-11/h1-9H,(H,19,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024 BindingDB Entry DOI: 10.7270/Q2BG2SB9
					More data for this Ligand-Target Pair

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