Compile Data Set for Download or QSAR

Found 67 hits with Last Name = 'deschaux' and Initial = 'o'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086344 (4-Naphthalen-2-yl-piperidine-3-carboxylic acid met...) Show SMILES COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c1-20-17(19)16-11-18-9-8-15(16)14-7-6-12-4-2-3-5-13(12)10-14/h2-7,10,15-16,18H,8-9,11H2,1H3/t15-,16?/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM30130 (CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...) Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50084718 ((3,4-Dichloro-phenyl)-[4-(3,4-dichloro-phenyl)-4-h...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H17Cl4NO2/c1-24-7-6-19(26,12-3-5-15(21)17(23)9-12)13(10-24)18(25)11-2-4-14(20)16(22)8-11/h2-5,8-9,13,26H,6-7,10H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086344 (4-Naphthalen-2-yl-piperidine-3-carboxylic acid met...) Show SMILES COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c1-20-17(19)16-11-18-9-8-15(16)14-7-6-12-4-2-3-5-13(12)10-14/h2-7,10,15-16,18H,8-9,11H2,1H3/t15-,16?/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084718 ((3,4-Dichloro-phenyl)-[4-(3,4-dichloro-phenyl)-4-h...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H17Cl4NO2/c1-24-7-6-19(26,12-3-5-15(21)17(23)9-12)13(10-24)18(25)11-2-4-14(20)16(22)8-11/h2-5,8-9,13,26H,6-7,10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometry				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086340 (4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic a...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H23NO2/c1-21-13-12-18(19(14-21)20(22)23-2)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,18-19H,12-14H2,1-2H3/t18-,19?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86208 (cis-CPCA, -) Show SMILES CN1CCC([C@H](C1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H16ClNO2/c1-15-7-6-11(12(8-15)13(16)17)9-2-4-10(14)5-3-9/h2-5,11-12H,6-8H2,1H3,(H,16,17)/t11?,12-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50064497 ((S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carb...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H18ClNO2/c1-16-8-7-12(13(9-16)14(17)18-2)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50064497 ((S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carb...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H18ClNO2/c1-16-8-7-12(13(9-16)14(17)18-2)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086344 (4-Naphthalen-2-yl-piperidine-3-carboxylic acid met...) Show SMILES COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c1-20-17(19)16-11-18-9-8-15(16)14-7-6-12-4-2-3-5-13(12)10-14/h2-7,10,15-16,18H,8-9,11H2,1H3/t15-,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM86206 (CAS_8268 | CPCA, + | NSC_8268) Show SMILES CN1CCC([C@@H](C1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H16ClNO2/c1-15-7-6-11(12(8-15)13(16)17)9-2-4-10(14)5-3-9/h2-5,11-12H,6-8H2,1H3,(H,16,17)/t11?,12-/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM86208 (cis-CPCA, -) Show SMILES CN1CCC([C@H](C1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H16ClNO2/c1-15-7-6-11(12(8-15)13(16)17)9-2-4-10(14)5-3-9/h2-5,11-12H,6-8H2,1H3,(H,16,17)/t11?,12-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086345 (1-Methyl-4-naphthalen-1-yl-piperidine-3-carboxylic...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1cccc2ccccc12 Show InChI InChI=1S/C18H21NO2/c1-19-11-10-16(17(12-19)18(20)21-2)15-9-5-7-13-6-3-4-8-14(13)15/h3-9,16-17H,10-12H2,1-2H3/t16-,17?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-NE Uptake in rat parietal/occipital cortex				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM86207 (CAS_50-36-2 | COCAINE | NSC_446220) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2C |TLB:2:4:20:7.6,11:10:20:7.6| Show InChI InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086341 (1-Methyl-4-(4-vinyl-phenyl)-piperidine-3-carboxyli...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(C=C)cc1 Show InChI InChI=1S/C16H21NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h4-8,14-15H,1,9-11H2,2-3H3/t14-,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086341 (1-Methyl-4-(4-vinyl-phenyl)-piperidine-3-carboxyli...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(C=C)cc1 Show InChI InChI=1S/C16H21NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h4-8,14-15H,1,9-11H2,2-3H3/t14-,15?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT Uptake in rat mid brain.				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086340 (4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic a...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H23NO2/c1-21-13-12-18(19(14-21)20(22)23-2)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,18-19H,12-14H2,1-2H3/t18-,19?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	173	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086341 (1-Methyl-4-(4-vinyl-phenyl)-piperidine-3-carboxyli...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(C=C)cc1 Show InChI InChI=1S/C16H21NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h4-8,14-15H,1,9-11H2,2-3H3/t14-,15?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086339 (4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxy...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)C#C Show InChI InChI=1S/C16H19NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h1,5-8,14-15H,9-11H2,2-3H3/t14-,15?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM30130 (CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...) Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM86207 (CAS_50-36-2 | COCAINE | NSC_446220) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2C |TLB:2:4:20:7.6,11:10:20:7.6| Show InChI InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transporter (Rattus norvegicus)	BDBM50084718 ((3,4-Dichloro-phenyl)-[4-(3,4-dichloro-phenyl)-4-h...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H17Cl4NO2/c1-24-7-6-19(26,12-3-5-15(21)17(23)9-12)13(10-24)18(25)11-2-4-14(20)16(22)8-11/h2-5,8-9,13,26H,6-7,10H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for Inhibition of [3H]-NE Uptake in rat parietal/occipital cortex				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086339 (4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxy...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)C#C Show InChI InChI=1S/C16H19NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h1,5-8,14-15H,9-11H2,2-3H3/t14-,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086340 (4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic a...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H23NO2/c1-21-13-12-18(19(14-21)20(22)23-2)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,18-19H,12-14H2,1-2H3/t18-,19?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	231	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Binding Affinity to Dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086342 (4-(4-Ethyl-phenyl)-1-methyl-piperidine-3-carboxyli...) Show SMILES CCc1ccc(cc1)[C@H]1CCN(C)CC1C(=O)OC Show InChI InChI=1S/C16H23NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h5-8,14-15H,4,9-11H2,1-3H3/t14-,15?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	255	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	274	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-DA Uptake was measured by liquid scintillation spectrometry				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86207 (CAS_50-36-2 | COCAINE | NSC_446220) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2C |TLB:2:4:20:7.6,11:10:20:7.6| Show InChI InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	275	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86206 (CAS_8268 | CPCA, + | NSC_8268) Show SMILES CN1CCC([C@@H](C1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H16ClNO2/c1-15-7-6-11(12(8-15)13(16)17)9-2-4-10(14)5-3-9/h2-5,11-12H,6-8H2,1H3,(H,16,17)/t11?,12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 143-50 (2003) Article DOI: 10.1124/jpet.102.046318 BindingDB Entry DOI: 10.7270/Q2R20ZZ8
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086345 (1-Methyl-4-naphthalen-1-yl-piperidine-3-carboxylic...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1cccc2ccccc12 Show InChI InChI=1S/C18H21NO2/c1-19-11-10-16(17(12-19)18(20)21-2)15-9-5-7-13-6-3-4-8-14(13)15/h3-9,16-17H,10-12H2,1-2H3/t16-,17?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	281	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086345 (1-Methyl-4-naphthalen-1-yl-piperidine-3-carboxylic...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1cccc2ccccc12 Show InChI InChI=1S/C18H21NO2/c1-19-11-10-16(17(12-19)18(20)21-2)15-9-5-7-13-6-3-4-8-14(13)15/h3-9,16-17H,10-12H2,1-2H3/t16-,17?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	304	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086338 (4-(4-Allyl-phenyl)-1-methyl-piperidine-3-carboxyli...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(CC=C)cc1 Show InChI InChI=1S/C17H23NO2/c1-4-5-13-6-8-14(9-7-13)15-10-11-18(2)12-16(15)17(19)20-3/h4,6-9,15-16H,1,5,10-12H2,2-3H3/t15-,16?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084716 ((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(C)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C21H25NO2/c1-15-4-8-17(9-5-15)20(23)19-14-22(3)13-12-21(19,24)18-10-6-16(2)7-11-18/h4-11,19,24H,12-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-DA Uptake at Dopamine transporter in rat cortex was measured by liquid scintillation spectrometry				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086339 (4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxy...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)C#C Show InChI InChI=1S/C16H19NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h1,5-8,14-15H,9-11H2,2-3H3/t14-,15?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	364	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50064497 ((S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carb...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI InChI=1S/C14H18ClNO2/c1-16-8-7-12(13(9-16)14(17)18-2)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3/t12-,13?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	391	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	423	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084716 ((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(C)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C21H25NO2/c1-15-4-8-17(9-5-15)20(23)19-14-22(3)13-12-21(19,24)18-10-6-16(2)7-11-18/h4-11,19,24H,12-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	492	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Binding Affinity to cocaine site of Dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086338 (4-(4-Allyl-phenyl)-1-methyl-piperidine-3-carboxyli...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(CC=C)cc1 Show InChI InChI=1S/C17H23NO2/c1-4-5-13-6-8-14(9-7-13)15-10-11-18(2)12-16(15)17(19)20-3/h4,6-9,15-16H,1,5,10-12H2,2-3H3/t15-,16?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	964	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086338 (4-(4-Allyl-phenyl)-1-methyl-piperidine-3-carboxyli...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(CC=C)cc1 Show InChI InChI=1S/C17H23NO2/c1-4-5-13-6-8-14(9-7-13)15-10-11-18(2)12-16(15)17(19)20-3/h4,6-9,15-16H,1,5,10-12H2,2-3H3/t15-,16?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50086342 (4-(4-Ethyl-phenyl)-1-methyl-piperidine-3-carboxyli...) Show SMILES CCc1ccc(cc1)[C@H]1CCN(C)CC1C(=O)OC Show InChI InChI=1S/C16H23NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h5-8,14-15H,4,9-11H2,1-3H3/t14-,15?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50084716 ((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(C)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C21H25NO2/c1-15-4-8-17(9-5-15)20(23)19-14-22(3)13-12-21(19,24)18-10-6-16(2)7-11-18/h4-11,19,24H,12-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for Inhibition of [3H]-5-HT Uptake in rat mid brain.				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086342 (4-(4-Ethyl-phenyl)-1-methyl-piperidine-3-carboxyli...) Show SMILES CCc1ccc(cc1)[C@H]1CCN(C)CC1C(=O)OC Show InChI InChI=1S/C16H23NO2/c1-4-12-5-7-13(8-6-12)14-9-10-17(2)11-15(14)16(18)19-3/h5-8,14-15H,4,9-11H2,1-3H3/t14-,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50084718 ((3,4-Dichloro-phenyl)-[4-(3,4-dichloro-phenyl)-4-h...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H17Cl4NO2/c1-24-7-6-19(26,12-3-5-15(21)17(23)9-12)13(10-24)18(25)11-2-4-14(20)16(22)8-11/h2-5,8-9,13,26H,6-7,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for Inhibition of [3H]-5-HT Uptake in rat mid brain.				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM30130 (CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...) Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084722 ((4-Hydroxy-1-methyl-4-phenyl-piperidin-3-yl)-pheny...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H21NO2/c1-20-13-12-19(22,16-10-6-3-7-11-16)17(14-20)18(21)15-8-4-2-5-9-15/h2-11,17,22H,12-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-DA Uptake at Dopamine transporter in rat cortex was measured by liquid scintillation spectrometry				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50084720 ((2,4-Dichloro-phenyl)-[4-(2,4-dichloro-phenyl)-4-h...) Show SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(Cl)cc1Cl)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H17Cl4NO2/c1-24-7-6-19(26,14-5-3-12(21)9-17(14)23)15(10-24)18(25)13-4-2-11(20)8-16(13)22/h2-5,8-9,15,26H,6-7,10H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .				J Med Chem 43: 351-60 (2000) BindingDB Entry DOI: 10.7270/Q2ST7P39
					More data for this Ligand-Target Pair

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