Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM60996 (5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM67690 (1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM23223 (7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of human purified MPG binding to immobilized ethenoadenine containing 5'-TCGAGGATCCTGAGCTCGAGTCGACGXTCGCGAATTCTGCGGATCCAAGC-3' duplex olig... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of MPG in human A549 cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-3-methyladenine glycosylase (Homo sapiens (Human)) | BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Curated by ChEMBL | Assay Description Inhibition of MPG in human HeLa cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge... | Bioorg Med Chem 23: 1102-11 (2015) Article DOI: 10.1016/j.bmc.2014.12.067 BindingDB Entry DOI: 10.7270/Q2M32XHW | |||||||||||
More data for this Ligand-Target Pair |