Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50162995 (3-[1-(1,2-Dihydro-pyridin-2-yl)-1H-indazol-3-yl]-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525881 (CHEMBL4513792) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522731 (CHEMBL4441980) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522737 (CHEMBL4469925) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525891 (CHEMBL4463908) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525882 (CHEMBL4472098) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525890 (CHEMBL4582082) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525884 (CHEMBL4589676) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50162996 (3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522734 (CHEMBL4444819) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525893 (CHEMBL4567272) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522721 (CHEMBL4558340) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525883 (CHEMBL4468579) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50162990 (3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525887 (CHEMBL4444605) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525888 (CHEMBL4460982) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522707 (CHEMBL4436021) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525889 (CHEMBL4536588) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522722 (CHEMBL4540172) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522720 (CHEMBL4456601) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525886 (CHEMBL4476825) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522728 (CHEMBL4449022) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522713 (CHEMBL4473209) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522725 (CHEMBL4445178) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525892 (CHEMBL4540602) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522739 (CHEMBL4557989) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522730 (CHEMBL4437105) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522708 (CHEMBL4559572) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522718 (CHEMBL4513964) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522719 (CHEMBL4465107) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522738 (CHEMBL4576987) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522705 (CHEMBL4471941) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522735 (CHEMBL4452109) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522729 (CHEMBL4567337) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522714 (CHEMBL4434750) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522715 (CHEMBL4558907) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522706 (CHEMBL4464664) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522717 (CHEMBL4444404) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 255 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522705 (CHEMBL4471941) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522733 (CHEMBL4517914) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 285 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50163000 (3-(1-Piperazin-1-yl-1H-indazol-3-yl)-4-[1-(1,4,4a,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50017376 ((+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylm...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50525885 (CHEMBL4473724) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of human full length GCGR transfected in HEK293 cells assessed as reduction in glucagon-induced cAMP response by LANCE TR-FRET assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126668 BindingDB Entry DOI: 10.7270/Q2902776 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50162992 (3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50162993 (3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522736 (CHEMBL4439846) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522723 (CHEMBL4584712) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522711 (CHEMBL4554170) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50163002 (3-(1-Morpholin-2-yl-1H-indazol-3-yl)-4-[1-(1,4,4a,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Potassium channel HERG | J Med Chem 48: 1725-8 (2005) Article DOI: 10.1021/jm049478u BindingDB Entry DOI: 10.7270/Q2765DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50522709 (CHEMBL4524978) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research & Development, L.L.C. Curated by ChEMBL | Assay Description Antagonist activity at full length human recombinant GCGR transfected in HEK293 cells assessed as inhibition of glucagon-stimulated cAMP by by LANCE ... | Bioorg Med Chem Lett 29: 1974-1980 (2019) Article DOI: 10.1016/j.bmcl.2019.05.036 BindingDB Entry DOI: 10.7270/Q2KH0RR1 | |||||||||||
More data for this Ligand-Target Pair |
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