Compile Data Set for Download or QSAR

Found 19 hits with Last Name = 'eggenspiller' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280445 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=C(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 |w:12.12| Show InChI InChI=1S/C14H13FN5O4P/c15-10(25(22,23)24)5-8-3-1-2-4-9(8)6-20-7-17-11-12(20)18-14(16)19-13(11)21/h1-5,7H,6H2,(H2,22,23,24)(H3,16,18,19,21)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280447 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=CP([O-])([O-])=O)cnc2c(=O)[nH]1 |w:13.14| Show InChI InChI=1S/C14H14N5O4P/c15-14-17-12-11(13(20)18-14)16-8-19(12)7-10-4-2-1-3-9(10)5-6-24(21,22)23/h1-6,8H,7H2,(H2,21,22,23)(H3,15,17,18,20)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280445 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=C(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 |w:12.12| Show InChI InChI=1S/C14H13FN5O4P/c15-10(25(22,23)24)5-8-3-1-2-4-9(8)6-20-7-17-11-12(20)18-14(16)19-13(11)21/h1-5,7H,6H2,(H2,22,23,24)(H3,16,18,19,21)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280447 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=CP([O-])([O-])=O)cnc2c(=O)[nH]1 |w:13.14| Show InChI InChI=1S/C14H14N5O4P/c15-14-17-12-11(13(20)18-14)16-8-19(12)7-10-4-2-1-3-9(10)5-6-24(21,22)23/h1-6,8H,7H2,(H2,21,22,23)(H3,15,17,18,20)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280446 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3CC(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H14F2N5O4P/c15-14(16,26(23,24)25)5-8-3-1-2-4-9(8)6-21-7-18-10-11(21)19-13(17)20-12(10)22/h1-4,7H,5-6H2,(H2,23,24,25)(H3,17,19,20,22)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280446 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3CC(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H14F2N5O4P/c15-14(16,26(23,24)25)5-8-3-1-2-4-9(8)6-21-7-18-10-11(21)19-13(17)20-12(10)22/h1-4,7H,5-6H2,(H2,23,24,25)(H3,17,19,20,22)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50214705 (5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1,1-di...) Show SMILES Nc1nc2n(CCCCC(F)(F)P(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H14F2N5O4P/c11-10(12,22(19,20)21)3-1-2-4-17-5-14-6-7(17)15-9(13)16-8(6)18/h5H,1-4H2,(H2,19,20,21)(H3,13,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylase				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005795 (2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1cccs1 Show InChI InChI=1S/C10H10N6OS/c11-9-14-7-6(8(17)15-9)13-10(12)16(7)4-5-2-1-3-18-5/h1-3H,4H2,(H2,12,13)(H3,11,14,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylase				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005799 (2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one | CHE...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1ccccc1 Show InChI InChI=1S/C12H12N6O/c13-11-16-9-8(10(19)17-11)15-12(14)18(9)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,14,15)(H3,13,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylase				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280445 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=C(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 |w:12.12| Show InChI InChI=1S/C14H13FN5O4P/c15-10(25(22,23)24)5-8-3-1-2-4-9(8)6-20-7-17-11-12(20)18-14(16)19-13(11)21/h1-5,7H,6H2,(H2,22,23,24)(H3,16,18,19,21)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280445 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=C(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 |w:12.12| Show InChI InChI=1S/C14H13FN5O4P/c15-10(25(22,23)24)5-8-3-1-2-4-9(8)6-20-7-17-11-12(20)18-14(16)19-13(11)21/h1-5,7H,6H2,(H2,22,23,24)(H3,16,18,19,21)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280447 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=CP([O-])([O-])=O)cnc2c(=O)[nH]1 |w:13.14| Show InChI InChI=1S/C14H14N5O4P/c15-14-17-12-11(13(20)18-14)16-8-19(12)7-10-4-2-1-3-9(10)5-6-24(21,22)23/h1-6,8H,7H2,(H2,21,22,23)(H3,15,17,18,20)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280447 ((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...) Show SMILES Nc1nc2n(Cc3ccccc3C=CP([O-])([O-])=O)cnc2c(=O)[nH]1 |w:13.14| Show InChI InChI=1S/C14H14N5O4P/c15-14-17-12-11(13(20)18-14)16-8-19(12)7-10-4-2-1-3-9(10)5-6-24(21,22)23/h1-6,8H,7H2,(H2,21,22,23)(H3,15,17,18,20)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280446 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3CC(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H14F2N5O4P/c15-14(16,26(23,24)25)5-8-3-1-2-4-9(8)6-21-7-18-10-11(21)19-13(17)20-12(10)22/h1-4,7H,5-6H2,(H2,23,24,25)(H3,17,19,20,22)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280446 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3CC(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H14F2N5O4P/c15-14(16,26(23,24)25)5-8-3-1-2-4-9(8)6-21-7-18-10-11(21)19-13(17)20-12(10)22/h1-4,7H,5-6H2,(H2,23,24,25)(H3,17,19,20,22)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair