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Compile Data Set for Download or QSAR

Found 151 hits with Last Name = 'espitia' and Initial = 'sa'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056605
PNG
(7-Chloro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Show SMILES Cc1c(Cl)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C9H6ClN3O4/c1-3-4(10)2-5-6(7(3)13(16)17)12-9(15)8(14)11-5/h2H,1H3,(H2,11,12,14,15)
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n/an/a 4.70n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091637
PNG
(5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo...)
Show SMILES O=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H23N3O/c26-22-23-20-9-8-18(16-21(20)24-22)7-4-12-25-13-10-19(11-14-25)15-17-5-2-1-3-6-17/h1-3,5-6,8-9,16,19H,10-15H2,(H2,23,24,26)
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n/an/a 5.30n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038161
PNG
(6,7-Dichloro-3-hydroxy-5-nitro-3,4-dihydro-1H-quin...)
Show SMILES [O-][N+](=O)c1c(Cl)c(Cl)cc2[n-]c(=[OH+])c(=O)[nH]c12
Show InChI InChI=1S/C8H3Cl2N3O4/c9-2-1-3-5(6(4(2)10)13(16)17)12-8(15)7(14)11-3/h1H,(H2,11,12,14,15)
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n/an/a 5.90n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091635
PNG
(5-{3-[4-(3-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Show SMILES Fc1cccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1
Show InChI InChI=1S/C22H22FN3O/c23-19-5-1-3-18(14-19)13-17-8-11-26(12-9-17)10-2-4-16-6-7-20-21(15-16)25-22(27)24-20/h1,3,5-7,14-15,17H,8-13H2,(H2,24,25,27)
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n/an/a 6.10n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091636
PNG
(5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Show SMILES Fc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1
Show InChI InChI=1S/C22H22FN3O/c23-19-6-3-17(4-7-19)14-18-9-12-26(13-10-18)11-1-2-16-5-8-20-21(15-16)25-22(27)24-20/h3-8,15,18H,9-14H2,(H2,24,25,27)
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n/an/a 8.20n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056596
PNG
(7-Bromo-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Show SMILES Cc1c(Br)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C9H6BrN3O4/c1-3-4(10)2-5-6(7(3)13(16)17)12-9(15)8(14)11-5/h2H,1H3,(H2,11,12,14,15)
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n/an/a 8.70n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091647
PNG
(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-di...)
Show SMILES S=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H23N3S/c26-22-23-20-9-8-18(16-21(20)24-22)7-4-12-25-13-10-19(11-14-25)15-17-5-2-1-3-6-17/h1-3,5-6,8-9,16,19H,10-15H2,(H2,23,24,26)
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n/an/a 16n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091632
PNG
(5-{3-[4-(4-Methyl-benzyl)-piperidin-1-yl]-prop-1-y...)
Show SMILES Cc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1
Show InChI InChI=1S/C23H25N3O/c1-17-4-6-19(7-5-17)15-20-10-13-26(14-11-20)12-2-3-18-8-9-21-22(16-18)25-23(27)24-21/h4-9,16,20H,10-15H2,1H3,(H2,24,25,27)
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n/an/a 17n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091643
PNG
(5-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-prop-1-y...)
Show SMILES Clc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1
Show InChI InChI=1S/C22H22ClN3O/c23-19-6-3-17(4-7-19)14-18-9-12-26(13-10-18)11-1-2-16-5-8-20-21(15-16)25-22(27)24-20/h3-8,15,18H,9-14H2,(H2,24,25,27)
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n/an/a 19n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091626
PNG
(5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-yn...)
Show SMILES OC1(Cc2ccccc2)CCN(CC#Cc2ccc3[nH]c(=O)[nH]c3c2)CC1
Show InChI InChI=1S/C22H23N3O2/c26-21-23-19-9-8-17(15-20(19)24-21)7-4-12-25-13-10-22(27,11-14-25)16-18-5-2-1-3-6-18/h1-3,5-6,8-9,15,27H,10-14,16H2,(H2,23,24,26)
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n/an/a 19n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056618
PNG
(6,7-Dibromo-5-nitro-1,4-dihydro-quinoxaline-2,3-di...)
Show SMILES [O-][N+](=O)c1c(Br)c(Br)cc2[n-]c(=[OH+])c(=O)[nH]c12
Show InChI InChI=1S/C8H3Br2N3O4/c9-2-1-3-5(6(4(2)10)13(16)17)12-8(15)7(14)11-3/h1H,(H2,11,12,14,15)
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n/an/a 20n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C


(Rattus norvegicus (Rat))		BDBM50091629
PNG
(5-{3-[4-(4-Fluoro-benzyl)-4-hydroxy-piperidin-1-yl...)
Show SMILES OC1(Cc2ccc(F)cc2)CCN(CC#Cc2ccc3[nH]c(=O)[nH]c3c2)CC1
Show InChI InChI=1S/C22H22FN3O2/c23-18-6-3-17(4-7-18)15-22(28)9-12-26(13-10-22)11-1-2-16-5-8-19-20(14-16)25-21(27)24-19/h3-8,14,28H,9-13,15H2,(H2,24,25,27)
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n/an/a 24n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50079386
PNG
(4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...)
Show SMILES Oc1ccc(OCCN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H25NO2/c22-19-6-8-20(9-7-19)23-15-14-21-12-10-18(11-13-21)16-17-4-2-1-3-5-17/h1-9,18,22H,10-16H2
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n/an/a 25n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes

J Med Chem 42: 2993-3000 (1999)


Article DOI: 10.1021/jm990246i
BindingDB Entry DOI: 10.7270/Q2RX9B8W
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091628
PNG
(5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-...)
Show SMILES COc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1
Show InChI InChI=1S/C23H25N3O2/c1-28-20-7-4-18(5-8-20)15-19-10-13-26(14-11-19)12-2-3-17-6-9-21-22(16-17)25-23(27)24-21/h4-9,16,19H,10-15H2,1H3,(H2,24,25,27)
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n/an/a 26n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50079389
PNG
(4-{2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-ethoxy}-...)
Show SMILES Cc1ccc(CC2CCN(CCOc3ccc(O)cc3)CC2)cc1
Show InChI InChI=1S/C21H27NO2/c1-17-2-4-18(5-3-17)16-19-10-12-22(13-11-19)14-15-24-21-8-6-20(23)7-9-21/h2-9,19,23H,10-16H2,1H3
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n/an/a 28n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes

J Med Chem 42: 2993-3000 (1999)


Article DOI: 10.1021/jm990246i
BindingDB Entry DOI: 10.7270/Q2RX9B8W
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056620
PNG
(6-Chloro-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Show SMILES CCc1cc2[n-]c(=[OH+])c(=O)[nH]c2c(c1Cl)[N+]([O-])=O
Show InChI InChI=1S/C10H8ClN3O4/c1-2-4-3-5-7(8(6(4)11)14(17)18)13-10(16)9(15)12-5/h3H,2H2,1H3,(H2,12,13,15,16)
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n/an/a 29n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056595
PNG
(6,7-Dimethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-d...)
Show SMILES Cc1cc2[n-]c(=[OH+])c(=O)[nH]c2c(c1C)[N+]([O-])=O
Show InChI InChI=1S/C10H9N3O4/c1-4-3-6-7(8(5(4)2)13(16)17)12-10(15)9(14)11-6/h3H,1-2H3,(H2,11,12,14,15)
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n/an/a 29n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50079385
PNG
(1-[2-(4-Hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl...)
Show SMILES Cc1ccc(CC2(O)CCN(CCOc3ccc(O)cc3)CC2)cc1
Show InChI InChI=1S/C21H27NO3/c1-17-2-4-18(5-3-17)16-21(24)10-12-22(13-11-21)14-15-25-20-8-6-19(23)7-9-20/h2-9,23-24H,10-16H2,1H3
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n/an/a 43n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes

J Med Chem 42: 2993-3000 (1999)


Article DOI: 10.1021/jm990246i
BindingDB Entry DOI: 10.7270/Q2RX9B8W
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056600
PNG
(6-Chloro-7-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Show SMILES Cc1cc2[n-]c(=[OH+])c(=O)[nH]c2c(c1Cl)[N+]([O-])=O
Show InChI InChI=1S/C9H6ClN3O4/c1-3-2-4-6(7(5(3)10)13(16)17)12-9(15)8(14)11-4/h2H,1H3,(H2,11,12,14,15)
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n/an/a 45n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091645
PNG
(6-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-3H-ben...)
Show SMILES O=c1[nH]c2ccc(cc2o1)C#CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H22N2O2/c25-22-23-20-9-8-18(16-21(20)26-22)7-4-12-24-13-10-19(11-14-24)15-17-5-2-1-3-6-17/h1-3,5-6,8-9,16,19H,10-15H2,(H,23,25)
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n/an/a 49n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50079388
PNG
(4-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethoxy}-...)
Show SMILES Oc1ccc(OCCN2CCC(Cc3ccc(F)cc3)CC2)cc1
Show InChI InChI=1S/C20H24FNO2/c21-18-3-1-16(2-4-18)15-17-9-11-22(12-10-17)13-14-24-20-7-5-19(23)6-8-20/h1-8,17,23H,9-15H2
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes

J Med Chem 42: 2993-3000 (1999)


Article DOI: 10.1021/jm990246i
BindingDB Entry DOI: 10.7270/Q2RX9B8W
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056591
PNG
(7-Bromo-6-methoxy-5-nitro-1,4-dihydro-quinoxaline-...)
Show SMILES COc1c(Br)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C9H6BrN3O5/c1-18-7-3(10)2-4-5(6(7)13(16)17)12-9(15)8(14)11-4/h2H,1H3,(H2,11,12,14,15)
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n/an/a 64n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056598
PNG
(7-Methyl-8-nitro-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Show SMILES Cc1c(cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O)C#N
Show InChI InChI=1S/C10H6N4O4/c1-4-5(3-11)2-6-7(8(4)14(17)18)13-10(16)9(15)12-6/h2H,1H3,(H2,12,13,15,16)
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n/an/a 73n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056611
PNG
(6-Bromo-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2,...)
Show SMILES CCc1cc2[n-]c(=[OH+])c(=O)[nH]c2c(c1Br)[N+]([O-])=O
Show InChI InChI=1S/C10H8BrN3O4/c1-2-4-3-5-7(8(6(4)11)14(17)18)13-10(16)9(15)12-5/h3H,2H2,1H3,(H2,12,13,15,16)
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n/an/a 82n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091627
PNG
(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1,3-dih...)
Show SMILES O=c1[nH]c2ccc(cc2[nH]1)C#CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H25N3O/c27-23-24-21-10-9-19(17-22(21)25-23)8-4-5-13-26-14-11-20(12-15-26)16-18-6-2-1-3-7-18/h1-3,6-7,9-10,17,20H,5,11-16H2,(H2,24,25,27)
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n/an/a 89n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056597
PNG
(7-Fluoro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Show SMILES Cc1c(F)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C9H6FN3O4/c1-3-4(10)2-5-6(7(3)13(16)17)12-9(15)8(14)11-5/h2H,1H3,(H2,11,12,14,15)
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n/an/a 95n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C


(Rattus norvegicus (Rat))		BDBM50091649
PNG
(6-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1-meth...)
Show SMILES Cn1c2cc(ccc2[nH]c1=O)C#CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H25N3O/c1-25-22-17-19(9-10-21(22)24-23(25)27)8-5-13-26-14-11-20(12-15-26)16-18-6-3-2-4-7-18/h2-4,6-7,9-10,17,20H,11-16H2,1H3,(H,24,27)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2B NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C


(Rattus norvegicus (Rat))		BDBM50078498
PNG
(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Show SMILES Oc1ccc(cc1)C#CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H23NO/c23-21-10-8-18(9-11-21)7-4-14-22-15-12-20(13-16-22)17-19-5-2-1-3-6-19/h1-3,5-6,8-11,20,23H,12-17H2
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50007674
PNG
((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Show SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes

J Med Chem 42: 2993-3000 (1999)


Article DOI: 10.1021/jm990246i
BindingDB Entry DOI: 10.7270/Q2RX9B8W
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091634
PNG
(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-di...)
Show SMILES O=C1Cc2cc(ccc2N1)C#CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H24N2O/c26-23-17-21-16-19(8-9-22(21)24-23)7-4-12-25-13-10-20(11-14-25)15-18-5-2-1-3-6-18/h1-3,5-6,8-9,16,20H,10-15,17H2,(H,24,26)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091642
PNG
(6-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-3H-benz...)
Show SMILES O=c1[nH]c2ccc(cc2o1)C#CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H24N2O2/c26-23-24-21-10-9-19(17-22(21)27-23)8-4-5-13-25-14-11-20(12-15-25)16-18-6-2-1-3-7-18/h1-3,6-7,9-10,17,20H,5,11-16H2,(H,24,26)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM22778
PNG
(6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...)
Show SMILES Clc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl
Show InChI InChI=1S/C8H4Cl2N2O2/c9-3-1-5-6(2-4(3)10)12-8(14)7(13)11-5/h1-2H,(H,11,13)(H,12,14)
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n/an/a 130n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056592
PNG
(7-Chloro-6-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Show SMILES CCc1c(Cl)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C10H8ClN3O4/c1-2-4-5(11)3-6-7(8(4)14(17)18)13-10(16)9(15)12-6/h3H,2H2,1H3,(H2,12,13,15,16)
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n/an/a 130n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056615
PNG
(5-Amino-7-chloro-6-methyl-1,4-dihydro-quinoxaline-...)
Show SMILES Cc1c(Cl)cc2[nH]c(=O)c(=O)[nH]c2c1N
Show InChI InChI=1S/C9H8ClN3O2/c1-3-4(10)2-5-7(6(3)11)13-9(15)8(14)12-5/h2H,11H2,1H3,(H,12,14)(H,13,15)
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CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056621
PNG
(7-Chloro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline...)
Show SMILES COc1c(Cl)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C9H6ClN3O5/c1-18-7-3(10)2-4-5(6(7)13(16)17)12-9(15)8(14)11-4/h2H,1H3,(H2,11,12,14,15)
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CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056606
PNG
(6,7-Diethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-di...)
Show SMILES CCc1cc2[n-]c(=[OH+])c(=O)[nH]c2c(c1CC)[N+]([O-])=O
Show InChI InChI=1S/C12H13N3O4/c1-3-6-5-8-9(14-12(17)11(16)13-8)10(15(18)19)7(6)4-2/h5H,3-4H2,1-2H3,(H2,13,14,16,17)
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n/an/a 160n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C


(Rattus norvegicus (Rat))		BDBM50078480
PNG
(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Show SMILES Oc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H25NO/c24-22-11-9-19(10-12-22)6-4-5-15-23-16-13-21(14-17-23)18-20-7-2-1-3-8-20/h1-3,7-12,21,24H,5,13-18H2
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091633
PNG
(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1,3-dih...)
Show SMILES S=c1[nH]c2ccc(cc2[nH]1)C#CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H25N3S/c27-23-24-21-10-9-19(17-22(21)25-23)8-4-5-13-26-14-11-20(12-15-26)16-18-6-2-1-3-7-18/h1-3,6-7,9-10,17,20H,5,11-16H2,(H2,24,25,27)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091640
PNG
(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-benz...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1ccc2nn[nH]c2c1
Show InChI InChI=1S/C22H24N4/c1-2-6-18(7-3-1)16-20-11-14-26(15-12-20)13-5-4-8-19-9-10-21-22(17-19)24-25-23-21/h1-3,6-7,9-10,17,20H,5,11-16H2,(H,23,24,25)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091648
PNG
(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-inda...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1ccc2[nH]ncc2c1
Show InChI InChI=1S/C23H25N3/c1-2-6-19(7-3-1)16-21-11-14-26(15-12-21)13-5-4-8-20-9-10-23-22(17-20)18-24-25-23/h1-3,6-7,9-10,17-18,21H,5,11-16H2,(H,24,25)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091644
PNG
(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1,3-dih...)
Show SMILES O=C1Cc2cc(ccc2N1)C#CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C24H26N2O/c27-24-18-22-17-20(9-10-23(22)25-24)8-4-5-13-26-14-11-21(12-15-26)16-19-6-2-1-3-7-19/h1-3,6-7,9-10,17,21H,5,11-16,18H2,(H,25,27)
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n/an/a 320n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091641
PNG
(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-ind...)
Show SMILES C(C#Cc1ccc2[nH]ncc2c1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H23N3/c1-2-5-18(6-3-1)15-20-10-13-25(14-11-20)12-4-7-19-8-9-22-21(16-19)17-23-24-22/h1-3,5-6,8-9,16-17,20H,10-15H2,(H,23,24)
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n/an/a 380n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50091639
PNG
(5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-ben...)
Show SMILES C(C#Cc1ccc2nn[nH]c2c1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H22N4/c1-2-5-17(6-3-1)15-19-10-13-25(14-11-19)12-4-7-18-8-9-20-21(16-18)23-24-22-20/h1-3,5-6,8-9,16,19H,10-15H2,(H,22,23,24)
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n/an/a 420n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50048173
PNG
(C,C,C-Trifluoro-N-(7-nitro-2-oxo-1,2-dihydro-quino...)
Show SMILES [O-][N+](=O)c1ccc2cc(NS(=O)(=O)C(F)(F)F)c(=[OH+])[n-]c2c1
Show InChI InChI=1S/C10H6F3N3O5S/c11-10(12,13)22(20,21)15-8-3-5-1-2-6(16(18)19)4-7(5)14-9(8)17/h1-4,15H,(H,14,17)
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n/an/a 620n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]-DCKA to N-methyl-D-aspartate glutamate receptor 1 in rat brain membrane

J Med Chem 40: 3679-86 (1997)


Article DOI: 10.1021/jm970396y
BindingDB Entry DOI: 10.7270/Q2S75FF8
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C


(Rattus norvegicus (Rat))		BDBM50091625
PNG
(5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indo...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1ccc2[nH]ccc2c1
Show InChI InChI=1S/C24H26N2/c1-2-6-20(7-3-1)18-22-12-16-26(17-13-22)15-5-4-8-21-9-10-24-23(19-21)11-14-25-24/h1-3,6-7,9-11,14,19,22,25H,5,12-13,15-18H2
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n/an/a 630n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytes

J Med Chem 43: 3408-19 (2000)


BindingDB Entry DOI: 10.7270/Q2VH5N26
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50079390
PNG
(4-Benzyl-1-(2-phenoxy-ethyl)-piperidine | CHEMBL10...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)Oc1ccccc1
Show InChI InChI=1S/C20H25NO/c1-3-7-18(8-4-1)17-19-11-13-21(14-12-19)15-16-22-20-9-5-2-6-10-20/h1-10,19H,11-17H2
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n/an/a 630n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes

J Med Chem 42: 2993-3000 (1999)


Article DOI: 10.1021/jm990246i
BindingDB Entry DOI: 10.7270/Q2RX9B8W
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056593
PNG
(7-Chloro-6-ethylsulfanyl-5-nitro-1,4-dihydro-quino...)
Show SMILES CCSc1c(Cl)cc2[n-]c(=[OH+])c(=O)[nH]c2c1[N+]([O-])=O
Show InChI InChI=1S/C10H8ClN3O4S/c1-2-19-8-4(11)3-5-6(7(8)14(17)18)13-10(16)9(15)12-5/h3H,2H2,1H3,(H2,12,13,15,16)
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n/an/a 640n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50060699
PNG
(7-Nitro-5-oxy-1,4-dihydro-pyrido[2,3-b]pyrazine-2,...)
Show SMILES [O-][N+](=O)c1c[n+]([O-])c2[n-]c(=[OH+])c(=[OH+])[n-]c2c1
Show InChI InChI=1S/C7H4N4O5/c12-6-7(13)9-5-4(8-6)1-3(11(15)16)2-10(5)14/h1-2H,(H2,8,9,12,13)
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n/an/a 690n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Binding affinity in rat brain cortical membranes by the displacement of [3H]- DCKA at N-methyl-D-aspartate glutamate receptor 1

J Med Chem 40: 3679-86 (1997)


Article DOI: 10.1021/jm970396y
BindingDB Entry DOI: 10.7270/Q2S75FF8
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056622
PNG
(6-Chloro-7-methyl-1,4-dihydro-quinoxaline-2,3-dion...)
Show SMILES Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl
Show InChI InChI=1S/C9H7ClN2O2/c1-4-2-6-7(3-5(4)10)12-9(14)8(13)11-6/h2-3H,1H3,(H,11,13)(H,12,14)
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n/an/a 780n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...

J Med Chem 40: 730-8 (1997)


Article DOI: 10.1021/jm960654b
BindingDB Entry DOI: 10.7270/Q2NZ86RJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50060694
PNG
(7-Bromo-5-oxy-1,4-dihydro-pyrido[2,3-b]pyrazine-2,...)
Show SMILES [O-][n+]1cc(Br)cc2[n-]c(=[OH+])c(=[OH+])[n-]c12
Show InChI InChI=1S/C7H4BrN3O3/c8-3-1-4-5(11(14)2-3)10-7(13)6(12)9-4/h1-2H,(H2,9,10,12,13)
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n/an/a 1.00E+3n/an/an/an/an/an/a



CoCensys Inc.

Curated by ChEMBL


Assay Description
Binding affinity in rat brain cortical membranes by the displacement of [3H]- DCKA at N-methyl-D-aspartate glutamate receptor 1

J Med Chem 40: 3679-86 (1997)


Article DOI: 10.1021/jm970396y
BindingDB Entry DOI: 10.7270/Q2S75FF8
More data for this
Ligand-Target Pair
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