Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50073274 (3-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the inhibition of [3H]-8-OH-DPAT binding to rat hippocampus membrane (5-HT1A receptor) | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50073273 (3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propox...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the inhibition of [3H]-8-OH-DPAT binding to rat hippocampus membrane (5-HT1A receptor) | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50073272 (4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the inhibition of [3H]-8-OH-DPAT binding to rat hippocampus membrane (5-HT1A receptor) | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50073271 (7-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-chromen-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the inhibition of [3H]-8-OH-DPAT binding to rat hippocampus membrane (5-HT1A receptor) | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50073273 (3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in homogenated mouse fibroblast (LTK) cells transfected with human Dopamine receptor D2A using [3H]-ra... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50073274 (3-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in homogenated mouse fibroblast (LTK) cells transfected with human Dopamine receptor D2A using [3H]-ra... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50073272 (4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in homogenated mouse fibroblast (LTK) cells transfected with human Dopamine receptor D2A using [3H]-ra... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50073271 (7-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-chromen-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in homogenated mouse fibroblast (LTK) cells transfected with human Dopamine receptor D2A using [3H]-ra... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50073274 (3-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in chinese hamster ovary (CHO) cells transfected with human Dopamine receptor D3 using [3H]-raclopride... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50073273 (3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in chinese hamster ovary (CHO) cells transfected with human Dopamine receptor D3 using [3H]-raclopride... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50073271 (7-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-chromen-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in chinese hamster ovary (CHO) cells transfected with human Dopamine receptor D3 using [3H]-raclopride... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50073272 (4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vigo Curated by ChEMBL | Assay Description Compound was measured for the binding affinity in chinese hamster ovary (CHO) cells transfected with human Dopamine receptor D3 using [3H]-raclopride... | Bioorg Med Chem Lett 8: 3567-70 (1999) BindingDB Entry DOI: 10.7270/Q2CV4GWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor A (Danio rerio) | BDBM50241977 (CHEMBL4066758) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a |
IGBMC (Institute of Genetics and of Molecular and Cellular Biology) Curated by ChEMBL | Assay Description Agonist activity at zebrafish VDR LBD (156 to 453 residues) expressed in HEK293 EBNA cells harboring human CYP24-Tk-Luc plasmid assessed as induction... | Eur J Med Chem 134: 86-96 (2017) Article DOI: 10.1016/j.ejmech.2017.03.081 BindingDB Entry DOI: 10.7270/Q2N018QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor A (Danio rerio) | BDBM50241974 (CHEMBL4099875) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a |
IGBMC (Institute of Genetics and of Molecular and Cellular Biology) Curated by ChEMBL | Assay Description Agonist activity at zebrafish VDR LBD (156 to 453 residues) expressed in HEK293 EBNA cells harboring human CYP24-Tk-Luc plasmid assessed as induction... | Eur J Med Chem 134: 86-96 (2017) Article DOI: 10.1016/j.ejmech.2017.03.081 BindingDB Entry DOI: 10.7270/Q2N018QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor A (Danio rerio) | BDBM50241975 (CHEMBL4060864) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a |
IGBMC (Institute of Genetics and of Molecular and Cellular Biology) Curated by ChEMBL | Assay Description Agonist activity at zebrafish VDR LBD (156 to 453 residues) expressed in HEK293 EBNA cells harboring human CYP24-Tk-Luc plasmid assessed as induction... | Eur J Med Chem 134: 86-96 (2017) Article DOI: 10.1016/j.ejmech.2017.03.081 BindingDB Entry DOI: 10.7270/Q2N018QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor A (Danio rerio) | BDBM50241976 (CHEMBL4088053) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a |
IGBMC (Institute of Genetics and of Molecular and Cellular Biology) Curated by ChEMBL | Assay Description Agonist activity at zebrafish VDR LBD (156 to 453 residues) expressed in HEK293 EBNA cells harboring human CYP24-Tk-Luc plasmid assessed as induction... | Eur J Med Chem 134: 86-96 (2017) Article DOI: 10.1016/j.ejmech.2017.03.081 BindingDB Entry DOI: 10.7270/Q2N018QM | |||||||||||
More data for this Ligand-Target Pair |