BindingDB PrimarySearch

Found 10 hits with Last Name = 'fechner' and Initial = 'g'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18207 ((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...				J Nat Prod 71: 1063-5 (2008) Article DOI: 10.1021/np070655e BindingDB Entry DOI: 10.7270/Q23J3DVC
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carboxypeptidase B (Homo sapiens (Human))	BDBM50233004 (2-(3-carbamimidamidopropylidene)butanedioic acid \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of carboxypeptidase B				Bioorg Med Chem Lett 18: 1495-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.060 BindingDB Entry DOI: 10.7270/Q2GB23T5
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50225276 (6-(3,3'-dihydroxy-4'-sulfooxy-biphenyl-4-yloxy)-2,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of PTP1B				J Nat Prod 70: 1790-2 (2007) Article DOI: 10.1021/np070225o BindingDB Entry DOI: 10.7270/Q2DZ081R
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50225828 ((2Z,2'Z)-N,N'-{butane-1,4-diylbis[(methylimino)pro...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Displacement of [3H]SAM from Icmt relative to SAH				Bioorg Med Chem Lett 17: 6860-3 (2007) Article DOI: 10.1016/j.bmcl.2007.10.021 BindingDB Entry DOI: 10.7270/Q2MG7P73
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50225277 (2,8-dihydroxy-6-(3,3',4'-trihydroxy-biphenyl-4-ylo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of PTP1B				J Nat Prod 70: 1790-2 (2007) Article DOI: 10.1021/np070225o BindingDB Entry DOI: 10.7270/Q2DZ081R
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50479260 (APLYSAMINE 6) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of Icmt using [3H]SAM as substrate				J Nat Prod 71: 1066-7 (2008) Article DOI: 10.1021/np0706623 BindingDB Entry DOI: 10.7270/Q2M0488M
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole \| CHEMBL12...) Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...				J Nat Prod 71: 1063-5 (2008) Article DOI: 10.1021/np070655e BindingDB Entry DOI: 10.7270/Q23J3DVC
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50174412 (9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...) Show SMILES COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...				J Nat Prod 71: 1063-5 (2008) Article DOI: 10.1021/np070655e BindingDB Entry DOI: 10.7270/Q23J3DVC
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50250521 ((-)-dibromophakellin \| CHEMBL447696 \| dibromophake...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assay				Bioorg Med Chem 17: 2497-500 (2009) Article DOI: 10.1016/j.bmc.2009.01.065 BindingDB Entry DOI: 10.7270/Q2FJ2GPP
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50090256 ((R)-2-((S)-1,2-dihydroxyethyl)-4,5-dihydroxyfuran-...) Show SMILES OC[C@H](O)c1oc(O)c(O)c1O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assay				Bioorg Med Chem 17: 2497-500 (2009) Article DOI: 10.1016/j.bmc.2009.01.065 BindingDB Entry DOI: 10.7270/Q2FJ2GPP
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair