Compile Data Set for Download or QSAR

Found 117 hits with Last Name = 'fedorov' and Initial = 'ev'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318959 (CHEMBL1084337 | rac-9-isobutyl-5-methyl-12-(tetrah...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)14-33-23-10-7-17(24-6-4-5-11-35-24)12-19(23)26-20-13-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)15-32(3)31-22/h7,10,12,15-16,24H,4-6,8-9,11,13-14H2,1-3H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318963 (CHEMBL1084061 | rac-5-methyl-9-propyl-12-(tetrahyd...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-3-11-32-22-10-7-16(23-6-4-5-12-34-23)13-18(22)25-19-14-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)15-31(2)30-21/h7,10,13,15,23H,3-6,8-9,11-12,14H2,1-2H3,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318946 (CHEMBL1085293 | rac-9-(2-hydroxyethyl)-5-methyl-12...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c3n(CCO)c3ccc(cc23)C2CCCCO2)n1 Show InChI InChI=1S/C27H28N4O3/c1-30-14-19-20(29-30)7-6-16-23(19)25-18(13-28-27(25)33)24-17-12-15(22-4-2-3-11-34-22)5-8-21(17)31(9-10-32)26(16)24/h5,8,12,14,22,32H,2-4,6-7,9-11,13H2,1H3,(H,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318960 (CHEMBL1082503 | rac-5-methyl-12-(tetrahydro-2H-pyr...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4[nH]c32)C2CCCCO2)n1 Show InChI InChI=1S/C25H24N4O2/c1-29-12-17-19(28-29)8-6-14-21(17)23-16(11-26-25(23)30)22-15-10-13(20-4-2-3-9-31-20)5-7-18(15)27-24(14)22/h5,7,10,12,20,27H,2-4,6,8-9,11H2,1H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50318958 (CHEMBL1082829 | rac-9-butyl-5-methyl-12-(tetrahydr...) Show SMILES CCCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-3-4-12-33-23-11-8-17(24-7-5-6-13-35-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)9-10-22-21(25)16-32(2)31-22/h8,11,14,16,24H,3-7,9-10,12-13,15H2,1-2H3,(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR3 at 3 uM				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318962 (CHEMBL1083757 | rac-9-ethyl-5-methyl-12-(tetrahydr...) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C27H28N4O2/c1-3-31-21-10-7-15(22-6-4-5-11-33-22)12-17(21)24-18-13-28-27(32)25(18)23-16(26(24)31)8-9-20-19(23)14-30(2)29-20/h7,10,12,14,22H,3-6,8-9,11,13H2,1-2H3,(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318957 (9-(2-hydroxyethyl)-6-methyl-12-(tetrahydro-2H-pyra...) Show SMILES Cn1ncc-2c1CCc1c-2c2C(=O)NCc2c2c1n(CCO)c1ccc(cc21)C1CCCCO1 Show InChI InChI=1S/C27H28N4O3/c1-30-20-8-6-16-23(18(20)14-29-30)25-19(13-28-27(25)33)24-17-12-15(22-4-2-3-11-34-22)5-7-21(17)31(9-10-32)26(16)24/h5,7,12,14,22,32H,2-4,6,8-11,13H2,1H3,(H,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318963 (CHEMBL1084061 | rac-5-methyl-9-propyl-12-(tetrahyd...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-3-11-32-22-10-7-16(23-6-4-5-12-34-23)13-18(22)25-19-14-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)15-31(2)30-21/h7,10,13,15,23H,3-6,8-9,11-12,14H2,1-2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318949 (6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tet...) Show SMILES Cn1ncc-2c1CCc1c-2c2C(=O)NCc2c2c3cc(ccc3[nH]c12)C1CCCCO1 Show InChI InChI=1S/C25H24N4O2/c1-29-19-8-6-14-21(16(19)12-27-29)23-17(11-26-25(23)30)22-15-10-13(20-4-2-3-9-31-20)5-7-18(15)28-24(14)22/h5,7,10,12,20,28H,2-4,6,8-9,11H2,1H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50318959 (CHEMBL1084337 | rac-9-isobutyl-5-methyl-12-(tetrah...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)14-33-23-10-7-17(24-6-4-5-11-35-24)12-19(23)26-20-13-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)15-32(3)31-22/h7,10,12,15-16,24H,4-6,8-9,11,13-14H2,1-3H3,(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR3 at 3 uM				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318970 (CHEMBL1082755 | rac-9-allyl-5-methyl-12-(tetrahydr...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(CC=C)c32)C2CCCCO2)n1 Show InChI InChI=1S/C28H28N4O2/c1-3-11-32-22-10-7-16(23-6-4-5-12-34-23)13-18(22)25-19-14-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)15-31(2)30-21/h3,7,10,13,15,23H,1,4-6,8-9,11-12,14H2,2H3,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318951 (9-ethyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7...) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C27H28N4O2/c1-3-31-21-9-7-15(22-6-4-5-11-33-22)12-17(21)24-19-13-28-27(32)25(19)23-16(26(24)31)8-10-20-18(23)14-29-30(20)2/h7,9,12,14,22H,3-6,8,10-11,13H2,1-2H3,(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318961 (CHEMBL1082826 | rac-5,9-dimethyl-12-(tetrahydro-2H...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(C)c32)C2CCCCO2)n1 Show InChI InChI=1S/C26H26N4O2/c1-29-13-18-19(28-29)8-7-15-22(18)24-17(12-27-26(24)31)23-16-11-14(21-5-3-4-10-32-21)6-9-20(16)30(2)25(15)23/h6,9,11,13,21H,3-5,7-8,10,12H2,1-2H3,(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318958 (CHEMBL1082829 | rac-9-butyl-5-methyl-12-(tetrahydr...) Show SMILES CCCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-3-4-12-33-23-11-8-17(24-7-5-6-13-35-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)9-10-22-21(25)16-32(2)31-22/h8,11,14,16,24H,3-7,9-10,12-13,15H2,1-2H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318959 (CHEMBL1084337 | rac-9-isobutyl-5-methyl-12-(tetrah...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)14-33-23-10-7-17(24-6-4-5-11-35-24)12-19(23)26-20-13-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)15-32(3)31-22/h7,10,12,15-16,24H,4-6,8-9,11,13-14H2,1-3H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318962 (CHEMBL1083757 | rac-9-ethyl-5-methyl-12-(tetrahydr...) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C27H28N4O2/c1-3-31-21-10-7-15(22-6-4-5-11-33-22)12-17(21)24-18-13-28-27(32)25(18)23-16(26(24)31)8-9-20-19(23)14-30(2)29-20/h7,10,12,14,22H,3-6,8-9,11,13H2,1-2H3,(H,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318963 (CHEMBL1084061 | rac-5-methyl-9-propyl-12-(tetrahyd...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-3-11-32-22-10-7-16(23-6-4-5-12-34-23)13-18(22)25-19-14-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)15-31(2)30-21/h7,10,13,15,23H,3-6,8-9,11-12,14H2,1-2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318964 (CHEMBL1084062 | rac-9-isopropyl-5-methyl-12-(tetra...) Show SMILES CC(C)n1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-15(2)32-22-10-7-16(23-6-4-5-11-34-23)12-18(22)25-19-13-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)14-31(3)30-21/h7,10,12,14-15,23H,4-6,8-9,11,13H2,1-3H3,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318960 (CHEMBL1082503 | rac-5-methyl-12-(tetrahydro-2H-pyr...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4[nH]c32)C2CCCCO2)n1 Show InChI InChI=1S/C25H24N4O2/c1-29-12-17-19(28-29)8-6-14-21(17)23-16(11-26-25(23)30)22-15-10-13(20-4-2-3-9-31-20)5-7-18(15)27-24(14)22/h5,7,10,12,20,27H,2-4,6,8-9,11H2,1H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318964 (CHEMBL1084062 | rac-9-isopropyl-5-methyl-12-(tetra...) Show SMILES CC(C)n1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-15(2)32-22-10-7-16(23-6-4-5-11-34-23)12-18(22)25-19-13-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)14-31(3)30-21/h7,10,12,14-15,23H,4-6,8-9,11,13H2,1-3H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318958 (CHEMBL1082829 | rac-9-butyl-5-methyl-12-(tetrahydr...) Show SMILES CCCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-3-4-12-33-23-11-8-17(24-7-5-6-13-35-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)9-10-22-21(25)16-32(2)31-22/h8,11,14,16,24H,3-7,9-10,12-13,15H2,1-2H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318959 (CHEMBL1084337 | rac-9-isobutyl-5-methyl-12-(tetrah...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)14-33-23-10-7-17(24-6-4-5-11-35-24)12-19(23)26-20-13-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)15-32(3)31-22/h7,10,12,15-16,24H,4-6,8-9,11,13-14H2,1-3H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318962 (CHEMBL1083757 | rac-9-ethyl-5-methyl-12-(tetrahydr...) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C27H28N4O2/c1-3-31-21-10-7-15(22-6-4-5-11-33-22)12-17(21)24-18-13-28-27(32)25(18)23-16(26(24)31)8-9-20-19(23)14-30(2)29-20/h7,10,12,14,22H,3-6,8-9,11,13H2,1-2H3,(H,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318961 (CHEMBL1082826 | rac-5,9-dimethyl-12-(tetrahydro-2H...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(C)c32)C2CCCCO2)n1 Show InChI InChI=1S/C26H26N4O2/c1-29-13-18-19(28-29)8-7-15-22(18)24-17(12-27-26(24)31)23-16-11-14(21-5-3-4-10-32-21)6-9-20(16)30(2)25(15)23/h6,9,11,13,21H,3-5,7-8,10,12H2,1-2H3,(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50318959 (CHEMBL1084337 | rac-9-isobutyl-5-methyl-12-(tetrah...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)14-33-23-10-7-17(24-6-4-5-11-35-24)12-19(23)26-20-13-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)15-32(3)31-22/h7,10,12,15-16,24H,4-6,8-9,11,13-14H2,1-3H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 at 3 uM				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318948 (CHEMBL1085541 | rac-9-(2-(diethylamino)ethyl)-5-me...) Show SMILES CCN(CC)CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C31H37N5O2/c1-4-35(5-2)13-14-36-25-12-9-19(26-8-6-7-15-38-26)16-21(25)28-22-17-32-31(37)29(22)27-20(30(28)36)10-11-24-23(27)18-34(3)33-24/h9,12,16,18,26H,4-8,10-11,13-15,17H2,1-3H3,(H,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318947 (CHEMBL1085540 | rac-9-(3-hydroxypropyl)-5-methyl-1...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c3n(CCCO)c3ccc(cc23)C2CCCCO2)n1 Show InChI InChI=1S/C28H30N4O3/c1-31-15-20-21(30-31)8-7-17-24(20)26-19(14-29-28(26)34)25-18-13-16(23-5-2-3-12-35-23)6-9-22(18)32(27(17)25)10-4-11-33/h6,9,13,15,23,33H,2-5,7-8,10-12,14H2,1H3,(H,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318947 (CHEMBL1085540 | rac-9-(3-hydroxypropyl)-5-methyl-1...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c3n(CCCO)c3ccc(cc23)C2CCCCO2)n1 Show InChI InChI=1S/C28H30N4O3/c1-31-15-20-21(30-31)8-7-17-24(20)26-19(14-29-28(26)34)25-18-13-16(23-5-2-3-12-35-23)6-9-22(18)32(27(17)25)10-4-11-33/h6,9,13,15,23,33H,2-5,7-8,10-12,14H2,1H3,(H,29,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318945 (CHEMBL1082756 | rac-9-(2-ethoxyethyl)-5-methyl-12-...) Show SMILES CCOCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O3/c1-3-35-13-11-33-23-10-7-17(24-6-4-5-12-36-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)16-32(2)31-22/h7,10,14,16,24H,3-6,8-9,11-13,15H2,1-2H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318955 (9-isobutyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)15-33-23-9-7-17(24-6-4-5-11-35-24)12-19(23)26-21-13-30-29(34)27(21)25-18(28(26)33)8-10-22-20(25)14-31-32(22)3/h7,9,12,14,16,24H,4-6,8,10-11,13,15H2,1-3H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318970 (CHEMBL1082755 | rac-9-allyl-5-methyl-12-(tetrahydr...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(CC=C)c32)C2CCCCO2)n1 Show InChI InChI=1S/C28H28N4O2/c1-3-11-32-22-10-7-16(23-6-4-5-12-34-23)13-18(22)25-19-14-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)15-31(2)30-21/h3,7,10,13,15,23H,1,4-6,8-9,11-12,14H2,2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318952 (6-methyl-9-propyl-12-(tetrahydro-2H-pyran-2-yl)-6,...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-3-11-32-22-9-7-16(23-6-4-5-12-34-23)13-18(22)25-20-14-29-28(33)26(20)24-17(27(25)32)8-10-21-19(24)15-30-31(21)2/h7,9,13,15,23H,3-6,8,10-12,14H2,1-2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318964 (CHEMBL1084062 | rac-9-isopropyl-5-methyl-12-(tetra...) Show SMILES CC(C)n1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-15(2)32-22-10-7-16(23-6-4-5-11-34-23)12-18(22)25-19-13-29-28(33)26(19)24-17(27(25)32)8-9-21-20(24)14-31(3)30-21/h7,10,12,14-15,23H,4-6,8-9,11,13H2,1-3H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318965 (CHEMBL1084338 | rac-9-isopentyl-5-methyl-12-(tetra...) Show SMILES CC(C)CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C30H34N4O2/c1-17(2)11-12-34-24-10-7-18(25-6-4-5-13-36-25)14-20(24)27-21-15-31-30(35)28(21)26-19(29(27)34)8-9-23-22(26)16-33(3)32-23/h7,10,14,16-17,25H,4-6,8-9,11-13,15H2,1-3H3,(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318950 (6,9-dimethyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9...) Show SMILES Cn1ncc-2c1CCc1c-2c2C(=O)NCc2c2c3cc(ccc3n(C)c12)C1CCCCO1 Show InChI InChI=1S/C26H26N4O2/c1-29-19-8-6-14(21-5-3-4-10-32-21)11-16(19)23-18-12-27-26(31)24(18)22-15(25(23)29)7-9-20-17(22)13-28-30(20)2/h6,8,11,13,21H,3-5,7,9-10,12H2,1-2H3,(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318945 (CHEMBL1082756 | rac-9-(2-ethoxyethyl)-5-methyl-12-...) Show SMILES CCOCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O3/c1-3-35-13-11-33-23-10-7-17(24-6-4-5-12-36-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)16-32(2)31-22/h7,10,14,16,24H,3-6,8-9,11-13,15H2,1-2H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318958 (CHEMBL1082829 | rac-9-butyl-5-methyl-12-(tetrahydr...) Show SMILES CCCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-3-4-12-33-23-11-8-17(24-7-5-6-13-35-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)9-10-22-21(25)16-32(2)31-22/h8,11,14,16,24H,3-7,9-10,12-13,15H2,1-2H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318952 (6-methyl-9-propyl-12-(tetrahydro-2H-pyran-2-yl)-6,...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-3-11-32-22-9-7-16(23-6-4-5-12-34-23)13-18(22)25-20-14-29-28(33)26(20)24-17(27(25)32)8-10-21-19(24)15-30-31(21)2/h7,9,13,15,23H,3-6,8,10-12,14H2,1-2H3,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM24949 (3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...) Show SMILES CC(C)Oc1ccc-2c(CCc3c-2c2C(=O)NCc2c2c4ccccc4n(CCO)c32)c1 Show InChI InChI=1S/C27H26N2O3/c1-15(2)32-17-8-10-18-16(13-17)7-9-20-23(18)25-21(14-28-27(25)31)24-19-5-3-4-6-22(19)29(11-12-30)26(20)24/h3-6,8,10,13,15,30H,7,9,11-12,14H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	7.2	37
Cephalon					Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...				J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318946 (CHEMBL1085293 | rac-9-(2-hydroxyethyl)-5-methyl-12...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c3n(CCO)c3ccc(cc23)C2CCCCO2)n1 Show InChI InChI=1S/C27H28N4O3/c1-30-14-19-20(29-30)7-6-16-23(19)25-18(13-28-27(25)33)24-17-12-15(22-4-2-3-11-34-22)5-8-21(17)31(9-10-32)26(16)24/h5,8,12,14,22,32H,2-4,6-7,9-11,13H2,1H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50318958 (CHEMBL1082829 | rac-9-butyl-5-methyl-12-(tetrahydr...) Show SMILES CCCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-3-4-12-33-23-11-8-17(24-7-5-6-13-35-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)9-10-22-21(25)16-32(2)31-22/h8,11,14,16,24H,3-7,9-10,12-13,15H2,1-2H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 at 3 uM				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318955 (9-isobutyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-16(2)15-33-23-9-7-17(24-6-4-5-11-35-24)12-19(23)26-21-13-30-29(34)27(21)25-18(28(26)33)8-10-22-20(25)14-31-32(22)3/h7,9,12,14,16,24H,4-6,8,10-11,13,15H2,1-3H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318954 (9-butyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7...) Show SMILES CCCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C29H32N4O2/c1-3-4-12-33-23-10-8-17(24-7-5-6-13-35-24)14-19(23)26-21-15-30-29(34)27(21)25-18(28(26)33)9-11-22-20(25)16-31-32(22)2/h8,10,14,16,24H,3-7,9,11-13,15H2,1-2H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM24942 (CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...) Show SMILES CCSCc1ccc2n3[C@H]4C[C@](O)(C(=O)OC)[C@](C)(O4)n4c5ccc(CSCC)cc5c5c6CNC(=O)c6c(c2c1)c3c45 |r| Show InChI InChI=1S/C33H33N3O5S2/c1-5-42-15-17-7-9-22-19(11-17)26-27-21(14-34-30(27)37)25-20-12-18(16-43-6-2)8-10-23(20)36-29(25)28(26)35(22)24-13-33(39,31(38)40-4)32(36,3)41-24/h7-12,24,39H,5-6,13-16H2,1-4H3,(H,34,37)/t24-,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	7.2	37
Cephalon					Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...				J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318961 (CHEMBL1082826 | rac-5,9-dimethyl-12-(tetrahydro-2H...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(C)c32)C2CCCCO2)n1 Show InChI InChI=1S/C26H26N4O2/c1-29-13-18-19(28-29)8-7-15-22(18)24-17(12-27-26(24)31)23-16-11-14(21-5-3-4-10-32-21)6-9-20(16)30(2)25(15)23/h6,9,11,13,21H,3-5,7-8,10,12H2,1-2H3,(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318967 (CHEMBL1083454 | rac-9-cyclopentyl-5-methyl-12-(tet...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(C4CCCC4)c32)C2CCCCO2)n1 Show InChI InChI=1S/C30H32N4O2/c1-33-16-22-23(32-33)11-10-19-26(22)28-21(15-31-30(28)35)27-20-14-17(25-8-4-5-13-36-25)9-12-24(20)34(29(19)27)18-6-2-3-7-18/h9,12,14,16,18,25H,2-8,10-11,13,15H2,1H3,(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50318960 (CHEMBL1082503 | rac-5-methyl-12-(tetrahydro-2H-pyr...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4[nH]c32)C2CCCCO2)n1 Show InChI InChI=1S/C25H24N4O2/c1-29-12-17-19(28-29)8-6-14-21(17)23-16(11-26-25(23)30)22-15-10-13(20-4-2-3-9-31-20)5-7-18(15)27-24(14)22/h5,7,10,12,20,27H,2-4,6,8-9,11H2,1H3,(H,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE-2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318953 (9-isopropyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)...) Show SMILES CC(C)n1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1 Show InChI InChI=1S/C28H30N4O2/c1-15(2)32-22-9-7-16(23-6-4-5-11-34-23)12-18(22)25-20-13-29-28(33)26(20)24-17(27(25)32)8-10-21-19(24)14-30-31(21)3/h7,9,12,14-15,23H,4-6,8,10-11,13H2,1-3H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50318968 (CHEMBL1085291 | rac-9-cyclohexyl-5-methyl-12-(tetr...) Show SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(C4CCCCC4)c32)C2CCCCO2)n1 Show InChI InChI=1S/C31H34N4O2/c1-34-17-23-24(33-34)12-11-20-27(23)29-22(16-32-31(29)36)28-21-15-18(26-9-5-6-14-37-26)10-13-25(21)35(30(20)28)19-7-3-2-4-8-19/h10,13,15,17,19,26H,2-9,11-12,14,16H2,1H3,(H,32,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurements				Bioorg Med Chem Lett 20: 3356-60 (2010) Article DOI: 10.1016/j.bmcl.2010.04.021 BindingDB Entry DOI: 10.7270/Q2HT2PH9
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM24952 (20-(cyclopentyloxy)-3-(2-hydroxyethyl)-3,13-diazah...) Show SMILES OCCn1c2ccccc2c2c3CNC(=O)c3c-3c(CCc4cc(OC5CCCC5)ccc-34)c12 Show InChI InChI=1S/C29H28N2O3/c32-14-13-31-24-8-4-3-7-21(24)26-23-16-30-29(33)27(23)25-20-12-10-19(34-18-5-1-2-6-18)15-17(20)9-11-22(25)28(26)31/h3-4,7-8,10,12,15,18,32H,1-2,5-6,9,11,13-14,16H2,(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	7.2	37
Cephalon					Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...				J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09
					More data for this Ligand-Target Pair

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