Compile Data Set for Download or QSAR

Found 168 hits with Last Name = 'feese' and Initial = 'md'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50073854 (2,10-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...) Show SMILES OCC1OC(C(O)C(O)C1O)n1c2cc(O)ccc2c2c3C(=O)NC(=O)c3c3c4ccc(O)cc4[nH]c3c12 Show InChI InChI=1S/C26H21N3O9/c30-7-14-21(33)22(34)23(35)26(38-14)29-13-6-9(32)2-4-11(13)16-18-17(24(36)28-25(18)37)15-10-3-1-8(31)5-12(10)27-19(15)20(16)29/h1-6,14,21-23,26-27,30-35H,7H2,(H,28,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE BioStructures Curated by ChEMBL					Assay Description Inhibition of topoisomerase I-DNA complex in trapping assay				J Med Chem 48: 2336-45 (2005) Article DOI: 10.1021/jm049146p BindingDB Entry DOI: 10.7270/Q2CF9QVT
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50008935 ((20S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy...) Show SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)c(CN(C)C)c4cc3Cn1c2=O |r| Show InChI InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
deCODE BioStructures Curated by ChEMBL					Assay Description Inhibition of topoisomerase I-DNA complex in trapping assay				J Med Chem 48: 2336-45 (2005) Article DOI: 10.1021/jm049146p BindingDB Entry DOI: 10.7270/Q2CF9QVT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486277 (US10947210, Compound 14-7A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O9S/c1-35-32(37)30-26-19-25(21-7-8-21)27(20-29(26)45-31(30)22-9-11-23(34)12-10-22)36(46(2,40)41)13-14-42-15-16-43-17-18-44-28-6-4-3-5-24(28)33(38)39/h3-6,9-12,19-21H,7-8,13-18H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486076 (US10947210, Compound 06-7F) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOCc3cccc(c3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O9S/c1-36-33(38)31-28-19-27(23-6-7-23)29(20-30(28)46-32(31)24-8-10-26(35)11-9-24)37(47(2,41)42)12-13-43-14-15-44-16-17-45-21-22-4-3-5-25(18-22)34(39)40/h3-5,8-11,18-20,23H,6-7,12-17,21H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486194 (US10947210, Compound 11-6A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O8S/c1-35-32(37)30-27-19-26(22-7-8-22)28(20-29(27)44-31(30)23-9-11-24(34)12-10-23)36(45(2,40)41)14-16-43-18-17-42-15-13-21-5-3-4-6-25(21)33(38)39/h3-6,9-12,19-20,22H,7-8,13-18H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486200 (US10947210, Compound 11-6B) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCc3cccc(c3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O8S/c1-35-32(37)30-27-19-26(22-6-7-22)28(20-29(27)44-31(30)23-8-10-25(34)11-9-23)36(45(2,40)41)13-15-43-17-16-42-14-12-21-4-3-5-24(18-21)33(38)39/h3-5,8-11,18-20,22H,6-7,12-17H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486221 (US10947210, Compound 12-7A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCCc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O8S/c1-36-33(38)31-28-20-27(23-9-10-23)29(21-30(28)45-32(31)24-11-13-25(35)14-12-24)37(46(2,41)42)15-17-44-19-18-43-16-5-7-22-6-3-4-8-26(22)34(39)40/h3-4,6,8,11-14,20-21,23H,5,7,9-10,15-19H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486222 (US10947210, Compound 12-7B) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCCc3cccc(c3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O8S/c1-36-33(38)31-28-20-27(23-8-9-23)29(21-30(28)45-32(31)24-10-12-26(35)13-11-24)37(46(2,41)42)14-16-44-18-17-43-15-4-6-22-5-3-7-25(19-22)34(39)40/h3,5,7,10-13,19-21,23H,4,6,8-9,14-18H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486330 (US10947210, Compound 28-8B) Show SMILES CNC(=O)c1c(oc2cc(N(CCCCCOCCCC(C)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C31H39FN2O7S/c1-20(31(36)37)8-7-17-40-16-6-4-5-15-34(42(3,38)39)26-19-27-25(18-24(26)21-9-10-21)28(30(35)33-2)29(41-27)22-11-13-23(32)14-12-22/h11-14,18-21H,4-10,15-17H2,1-3H3,(H,33,35)(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486303 (US10947210, Compound 18-10B) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(cc3C)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O8S/c1-20-16-23(33(38)39)6-7-24(20)19-43-15-14-42-13-12-36(45(3,40)41)28-18-29-27(17-26(28)21-4-5-21)30(32(37)35-2)31(44-29)22-8-10-25(34)11-9-22/h6-11,16-18,21H,4-5,12-15,19H2,1-3H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486304 (US10947210, Compound 19-8A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccnc(Cl)c3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C30H31ClFN3O6S/c1-33-30(36)28-24-16-23(20-3-4-20)25(17-26(24)41-29(28)21-5-7-22(32)8-6-21)35(42(2,37)38)11-12-39-13-14-40-18-19-9-10-34-27(31)15-19/h5-10,15-17,20H,3-4,11-14,18H2,1-2H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486305 (US10947210, Compound 19-8B) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(Cl)nc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C30H31ClFN3O6S/c1-33-30(36)28-24-15-23(20-4-5-20)25(16-26(24)41-29(28)21-6-8-22(32)9-7-21)35(42(2,37)38)11-12-39-13-14-40-18-19-3-10-27(31)34-17-19/h3,6-10,15-17,20H,4-5,11-14,18H2,1-2H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486307 (US10947210, Compound 20-8) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(C(O)=O)c4ccccc34)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C36H35FN2O8S/c1-38-35(40)33-30-19-29(22-7-8-22)31(20-32(30)47-34(33)23-9-12-25(37)13-10-23)39(48(2,43)44)15-16-45-17-18-46-21-24-11-14-28(36(41)42)27-6-4-3-5-26(24)27/h3-6,9-14,19-20,22H,7-8,15-18,21H2,1-2H3,(H,38,40)(H,41,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486308 (US10947210, Compound 21-5) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCSC(C)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H29FN2O6S2/c1-16(30)36-13-12-34-11-10-29(37(3,32)33)22-15-23-21(14-20(22)17-4-5-17)24(26(31)28-2)25(35-23)18-6-8-19(27)9-7-18/h6-9,14-15,17H,4-5,10-13H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486321 (US10947210, Compound 26-7A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOC3(CCCC3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H39FN2O9S/c1-34-30(36)28-25-19-24(21-5-6-21)26(20-27(25)44-29(28)22-7-9-23(33)10-8-22)35(45(2,39)40)13-14-41-15-16-42-17-18-43-32(31(37)38)11-3-4-12-32/h7-10,19-21H,3-6,11-18H2,1-2H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486329 (US10947210, Compound 28-8A) Show SMILES CNC(=O)c1c(oc2cc(N(CCCCCOCCCCC(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C30H37FN2O7S/c1-32-30(36)28-24-18-23(20-9-10-20)25(19-26(24)40-29(28)21-11-13-22(31)14-12-21)33(41(2,37)38)15-5-3-6-16-39-17-7-4-8-27(34)35/h11-14,18-20H,3-10,15-17H2,1-2H3,(H,32,36)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50008923 ((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...) Show SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O |r| Show InChI InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE BioStructures Curated by ChEMBL					Assay Description Inhibition of topoisomerase I-DNA complex in trapping assay				J Med Chem 48: 2336-45 (2005) Article DOI: 10.1021/jm049146p BindingDB Entry DOI: 10.7270/Q2CF9QVT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM485959 (US10947210, Compound 02-10A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3cccc(c3)C(=O)\C=C(/O)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H35FN2O10S/c1-37-34(41)32-27-17-26(22-6-7-22)28(18-31(27)48-33(32)23-8-10-25(36)11-9-23)38(49(2,44)45)12-13-46-14-15-47-20-21-4-3-5-24(16-21)29(39)19-30(40)35(42)43/h3-5,8-11,16-19,22,40H,6-7,12-15,20H2,1-2H3,(H,37,41)(H,42,43)/b30-19-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM485967 (US10947210, Compound 02-10C) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOCCOCc3cccc(c3)C(=O)\C=C(/O)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C39H43FN2O12S/c1-41-38(45)36-31-21-30(26-6-7-26)32(22-35(31)54-37(36)27-8-10-29(40)11-9-27)42(55(2,48)49)12-13-50-14-15-51-16-17-52-18-19-53-24-25-4-3-5-28(20-25)33(43)23-34(44)39(46)47/h3-5,8-11,20-23,26,44H,6-7,12-19,24H2,1-2H3,(H,41,45)(H,46,47)/b34-23-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486035 (US10947210, Compound 03-8A) Show SMILES CCOC(=O)C(\O)=C\C(=O)c1cccc(COCCOCCCN(c2cc3oc(c(C(=O)NC)c3cc2C2CC2)-c2ccc(F)cc2)S(C)(=O)=O)c1 Show InChI InChI=1S/C38H41FN2O10S/c1-4-50-38(45)33(43)22-32(42)27-8-5-7-24(19-27)23-49-18-17-48-16-6-15-41(52(3,46)47)31-21-34-30(20-29(31)25-9-10-25)35(37(44)40-2)36(51-34)26-11-13-28(39)14-12-26/h5,7-8,11-14,19-22,25,43H,4,6,9-10,15-18,23H2,1-3H3,(H,40,44)/b33-22-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486054 (US10947210, Compound 06-6A | US10947210, Compound ...) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H33FN2O8S/c1-34-31(36)29-26-17-25(20-7-8-20)27(18-28(26)43-30(29)21-9-11-23(33)12-10-21)35(44(2,39)40)13-14-41-15-16-42-19-22-5-3-4-6-24(22)32(37)38/h3-6,9-12,17-18,20H,7-8,13-16,19H2,1-2H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486060 (US10947210, Compound 06-6D) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOCc3ccccc3C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H39FN2O9S/c1-37-34(39)32-29-20-28(23-8-9-23)30(21-31(29)47-33(32)24-10-12-26(36)13-11-24)38(48(3,41)42)14-15-44-16-17-45-18-19-46-22-25-6-4-5-7-27(25)35(40)43-2/h4-7,10-13,20-21,23H,8-9,14-19,22H2,1-3H3,(H,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486062 (US10947210, Compound 06-6E) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOCc3ccc(cc3)C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H39FN2O9S/c1-37-34(39)32-29-20-28(24-8-9-24)30(21-31(29)47-33(32)25-10-12-27(36)13-11-25)38(48(3,41)42)14-15-44-16-17-45-18-19-46-22-23-4-6-26(7-5-23)35(40)43-2/h4-7,10-13,20-21,24H,8-9,14-19,22H2,1-3H3,(H,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486054 (US10947210, Compound 06-6A | US10947210, Compound ...) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H33FN2O8S/c1-34-31(36)29-26-17-25(20-7-8-20)27(18-28(26)43-30(29)21-9-11-23(33)12-10-21)35(44(2,39)40)13-14-41-15-16-42-19-22-5-3-4-6-24(22)32(37)38/h3-6,9-12,17-18,20H,7-8,13-16,19H2,1-2H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486067 (US10947210, Compound 06-7B) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H33FN2O8S/c1-34-31(36)29-26-17-25(21-7-8-21)27(18-28(26)43-30(29)22-9-11-24(33)12-10-22)35(44(2,39)40)13-14-41-15-16-42-19-20-3-5-23(6-4-20)32(37)38/h3-6,9-12,17-18,21H,7-8,13-16,19H2,1-2H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486068 (US10947210, Compound 06-7C) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3cccc(c3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H33FN2O8S/c1-34-31(36)29-26-17-25(21-6-7-21)27(18-28(26)43-30(29)22-8-10-24(33)11-9-22)35(44(2,39)40)12-13-41-14-15-42-19-20-4-3-5-23(16-20)32(37)38/h3-5,8-11,16-18,21H,6-7,12-15,19H2,1-2H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486072 (US10947210, Compound 06-7D) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOCc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O9S/c1-36-33(38)31-28-19-27(22-7-8-22)29(20-30(28)46-32(31)23-9-11-25(35)12-10-23)37(47(2,41)42)13-14-43-15-16-44-17-18-45-21-24-5-3-4-6-26(24)34(39)40/h3-6,9-12,19-20,22H,7-8,13-18,21H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486075 (US10947210, Compound 06-7E | US10947210, Compound ...) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O9S/c1-36-33(38)31-28-19-27(23-7-8-23)29(20-30(28)46-32(31)24-9-11-26(35)12-10-24)37(47(2,41)42)13-14-43-15-16-44-17-18-45-21-22-3-5-25(6-4-22)34(39)40/h3-6,9-12,19-20,23H,7-8,13-18,21H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486088 (US10947210, Compound 06-8B3) Show SMILES CCCCOC(=O)c1ccc(COCCOCCN(c2cc3oc(c(C(=O)NC)c3cc2C2CC2)-c2ccc(F)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C36H41FN2O8S/c1-4-5-17-46-36(41)27-8-6-24(7-9-27)23-45-20-19-44-18-16-39(48(3,42)43)31-22-32-30(21-29(31)25-10-11-25)33(35(40)38-2)34(47-32)26-12-14-28(37)15-13-26/h6-9,12-15,21-22,25H,4-5,10-11,16-20,23H2,1-3H3,(H,38,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486089 (US10947210, Compound 06-8B4) Show SMILES CCCCCOC(=O)c1ccc(COCCOCCN(c2cc3oc(c(C(=O)NC)c3cc2C2CC2)-c2ccc(F)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C37H43FN2O8S/c1-4-5-6-18-47-37(42)28-9-7-25(8-10-28)24-46-21-20-45-19-17-40(49(3,43)44)32-23-33-31(22-30(32)26-11-12-26)34(36(41)39-2)35(48-33)27-13-15-29(38)16-14-27/h7-10,13-16,22-23,26H,4-6,11-12,17-21,24H2,1-3H3,(H,39,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486090 (US10947210, Compound 06-8B5) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(cc3)C(=O)OCC(N)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H36FN3O9S/c1-37-33(40)31-27-17-26(22-7-8-22)28(18-29(27)47-32(31)23-9-11-25(35)12-10-23)38(48(2,42)43)13-14-44-15-16-45-19-21-3-5-24(6-4-21)34(41)46-20-30(36)39/h3-6,9-12,17-18,22H,7-8,13-16,19-20H2,1-2H3,(H2,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486091 (US10947210, Compound 06-8B6) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(cc3)C(=O)OCSC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O8S2/c1-36-33(38)31-28-18-27(23-8-9-23)29(19-30(28)45-32(31)24-10-12-26(35)13-11-24)37(47(3,40)41)14-15-42-16-17-43-20-22-4-6-25(7-5-22)34(39)44-21-46-2/h4-7,10-13,18-19,23H,8-9,14-17,20-21H2,1-3H3,(H,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486096 (US10947210, Compound 06-8B7) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(cc3)C(=O)OCc3ccccc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C39H39FN2O8S/c1-41-38(43)36-33-22-32(28-12-13-28)34(23-35(33)50-37(36)29-14-16-31(40)17-15-29)42(51(2,45)46)18-19-47-20-21-48-24-27-8-10-30(11-9-27)39(44)49-25-26-6-4-3-5-7-26/h3-11,14-17,22-23,28H,12-13,18-21,24-25H2,1-2H3,(H,41,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486098 (US10947210, Compound 06-8B8) Show SMILES CCOC(=O)COC(=O)c1ccc(COCCOCCN(c2cc3oc(c(C(=O)NC)c3cc2C2CC2)-c2ccc(F)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C36H39FN2O10S/c1-4-47-32(40)22-48-36(42)26-7-5-23(6-8-26)21-46-18-17-45-16-15-39(50(3,43)44)30-20-31-29(19-28(30)24-9-10-24)33(35(41)38-2)34(49-31)25-11-13-27(37)14-12-25/h5-8,11-14,19-20,24H,4,9-10,15-18,21-22H2,1-3H3,(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486102 (US10947210, Compound 08-6) Show SMILES CNC(=O)c1c(oc2cc(N(CCOC(=O)CNC(=O)CCCC(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C29H32FN3O9S/c1-31-29(38)27-21-14-20(17-6-7-17)22(15-23(21)42-28(27)18-8-10-19(30)11-9-18)33(43(2,39)40)12-13-41-26(37)16-32-24(34)4-3-5-25(35)36/h8-11,14-15,17H,3-7,12-13,16H2,1-2H3,(H,31,38)(H,32,34)(H,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486103 (US10947210, Compound 09-14A) Show SMILES CNC(=O)c1c(oc2cc(N(CC(=O)NCC(=O)NCc3cccc(c3)C(=O)\C=C(/O)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H33FN4O10S/c1-37-34(45)32-25-13-24(20-6-7-20)26(14-29(25)50-33(32)21-8-10-23(36)11-9-21)40(51(2,48)49)18-31(44)39-17-30(43)38-16-19-4-3-5-22(12-19)27(41)15-28(42)35(46)47/h3-5,8-15,20,42H,6-7,16-18H2,1-2H3,(H,37,45)(H,38,43)(H,39,44)(H,46,47)/b28-15-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486191 (US10947210, Compound 11-5A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCc3ccccc3C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O8S/c1-36-33(38)31-28-20-27(23-8-9-23)29(21-30(28)45-32(31)24-10-12-25(35)13-11-24)37(46(3,40)41)15-17-44-19-18-43-16-14-22-6-4-5-7-26(22)34(39)42-2/h4-7,10-13,20-21,23H,8-9,14-19H2,1-3H3,(H,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486214 (US10947210, Compound 11-6C) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O8S/c1-35-32(37)30-27-19-26(22-7-8-22)28(20-29(27)44-31(30)23-9-11-25(34)12-10-23)36(45(2,40)41)14-16-43-18-17-42-15-13-21-3-5-24(6-4-21)33(38)39/h3-6,9-12,19-20,22H,7-8,13-18H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486220 (US10947210, Compound 12-6A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCCc3ccccc3C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H39FN2O8S/c1-37-34(39)32-29-21-28(24-10-11-24)30(22-31(29)46-33(32)25-12-14-26(36)15-13-25)38(47(3,41)42)16-18-45-20-19-44-17-6-8-23-7-4-5-9-27(23)35(40)43-2/h4-5,7,9,12-15,21-22,24H,6,8,10-11,16-20H2,1-3H3,(H,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486223 (US10947210, Compound 12-7C) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O8S/c1-36-33(38)31-28-20-27(23-9-10-23)29(21-30(28)45-32(31)24-11-13-26(35)14-12-24)37(46(2,41)42)15-17-44-19-18-43-16-3-4-22-5-7-25(8-6-22)34(39)40/h5-8,11-14,20-21,23H,3-4,9-10,15-19H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486224 (US10947210, Compound 13-7A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCCCc3ccc(cc3)C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O7S/c1-36-33(38)31-28-20-27(23-11-12-23)29(21-30(28)44-32(31)24-13-15-26(35)16-14-24)37(45(3,40)41)17-19-43-18-5-4-6-22-7-9-25(10-8-22)34(39)42-2/h7-10,13-16,20-21,23H,4-6,11-12,17-19H2,1-3H3,(H,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486225 (US10947210, Compound 13-7B) Show SMILES CNC(=O)c1c(oc2cc(N(CCCOCCCc3ccc(cc3)C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O7S/c1-36-33(38)31-28-20-27(23-11-12-23)29(21-30(28)44-32(31)24-13-15-26(35)16-14-24)37(45(3,40)41)17-5-19-43-18-4-6-22-7-9-25(10-8-22)34(39)42-2/h7-10,13-16,20-21,23H,4-6,11-12,17-19H2,1-3H3,(H,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486231 (US10947210, Compound 13-7C) Show SMILES CNC(=O)c1c(oc2cc(N(CCCCOCCc3ccc(cc3)C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O7S/c1-36-33(38)31-28-20-27(23-10-11-23)29(21-30(28)44-32(31)24-12-14-26(35)15-13-24)37(45(3,40)41)17-4-5-18-43-19-16-22-6-8-25(9-7-22)34(39)42-2/h6-9,12-15,20-21,23H,4-5,10-11,16-19H2,1-3H3,(H,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486233 (US10947210, Compound 13-7D) Show SMILES CNC(=O)c1c(oc2cc(N(CCCCCCCc3ccc(cc3)C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C35H39FN2O6S/c1-37-34(39)32-29-21-28(24-14-15-24)30(22-31(29)44-33(32)25-16-18-27(36)19-17-25)38(45(3,41)42)20-8-6-4-5-7-9-23-10-12-26(13-11-23)35(40)43-2/h10-13,16-19,21-22,24H,4-9,14-15,20H2,1-3H3,(H,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486235 (US10947210, Compound 13-8A) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCCCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O7S/c1-35-32(37)30-27-19-26(22-10-11-22)28(20-29(27)43-31(30)23-12-14-25(34)15-13-23)36(44(2,40)41)16-18-42-17-4-3-5-21-6-8-24(9-7-21)33(38)39/h6-9,12-15,19-20,22H,3-5,10-11,16-18H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486238 (US10947210, Compound 13-8B) Show SMILES CNC(=O)c1c(oc2cc(N(CCCOCCCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O7S/c1-35-32(37)30-27-19-26(22-10-11-22)28(20-29(27)43-31(30)23-12-14-25(34)15-13-23)36(44(2,40)41)16-4-18-42-17-3-5-21-6-8-24(9-7-21)33(38)39/h6-9,12-15,19-20,22H,3-5,10-11,16-18H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486239 (US10947210, Compound 13-8C) Show SMILES CNC(=O)c1c(oc2cc(N(CCCCOCCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O7S/c1-35-32(37)30-27-19-26(22-9-10-22)28(20-29(27)43-31(30)23-11-13-25(34)14-12-23)36(44(2,40)41)16-3-4-17-42-18-15-21-5-7-24(8-6-21)33(38)39/h5-8,11-14,19-20,22H,3-4,9-10,15-18H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486241 (US10947210, Compound 13-8D) Show SMILES CNC(=O)c1c(oc2cc(N(CCCCCCCc3ccc(cc3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H37FN2O6S/c1-36-33(38)31-28-20-27(23-13-14-23)29(21-30(28)43-32(31)24-15-17-26(35)18-16-24)37(44(2,41)42)19-7-5-3-4-6-8-22-9-11-25(12-10-22)34(39)40/h9-12,15-18,20-21,23H,3-8,13-14,19H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486246 (US10947210, Compound 14-6A) Show SMILES CCOC(=O)c1ccccc1OCCOCCOCCN(c1cc2oc(c(C(=O)NC)c2cc1C1CC1)-c1ccc(F)cc1)S(C)(=O)=O Show InChI InChI=1S/C35H39FN2O9S/c1-4-45-35(40)26-7-5-6-8-30(26)46-20-19-44-18-17-43-16-15-38(48(3,41)42)29-22-31-28(21-27(29)23-9-10-23)32(34(39)37-2)33(47-31)24-11-13-25(36)14-12-24/h5-8,11-14,21-23H,4,9-10,15-20H2,1-3H3,(H,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate k3a) (HCV))	BDBM486282 (US10947210, Compound 14-7B) Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOc3cccc(c3)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN2O9S/c1-35-32(37)30-27-19-26(21-6-7-21)28(20-29(27)45-31(30)22-8-10-24(34)11-9-22)36(46(2,40)41)12-13-42-14-15-43-16-17-44-25-5-3-4-23(18-25)33(38)39/h3-5,8-11,18-21H,6-7,12-17H2,1-2H3,(H,35,37)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
COCRYSTAL PHARMA, INC. US Patent					Assay Description The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...				US Patent US10947210 (2021) BindingDB Entry DOI: 10.7270/Q2CZ3B8J
					More data for this Ligand-Target Pair

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