BindingDB PrimarySearch

Found 23 hits with Last Name = 'feng' and Initial = 'by'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Eukaryotic peptide chain release factor GTP-binding subunit (Saccharomyces cerevisiae (strain ATCC 204508 / S28...)	BDBM50482421 (TERAIODOPHENOLPHATHALIN) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerizatio...				Nat Chem Biol 4: 197-9 (2008) Article DOI: 10.1038/nchembio.65 BindingDB Entry DOI: 10.7270/Q2028VD2
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Bifunctional coenzyme A synthase (Homo sapiens)	BDBM50263238 (CHEMBL4102651) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research , 5300 Chiron Way , Emeryville , California 94608 , United States. Curated by ChEMBL					Assay Description Inhibition of human PPAT				J Med Chem 61: 3309-3324 (2018) Article DOI: 10.1021/acs.jmedchem.7b01691 BindingDB Entry DOI: 10.7270/Q2S46VFK
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM34417 (2-(2,3-dimethylphenoxy)-N-[3-(5-phenyl-1,3,4-oxadi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211049 (CHEMBL227512 \| N-(4-(2,3,5,6-tetrafluoro-4-methoxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211053 (CHEMBL226664 \| N-{4-[3,4-bis(furan-2-amido)phenoxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM31770 (Exelderm \| Sulconazole Nitrate \| cid_65495 \| sulco...) Show SMILES Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM31774 (CHEMBL104 \| Canesten \| Clotrimazole \| Lotrimin \| M...) Show SMILES Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211053 (CHEMBL226664 \| N-{4-[3,4-bis(furan-2-amido)phenoxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM23223 (7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM34417 (2-(2,3-dimethylphenoxy)-N-[3-(5-phenyl-1,3,4-oxadi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211049 (CHEMBL227512 \| N-(4-(2,3,5,6-tetrafluoro-4-methoxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM23223 (7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM37510 (6-methyl-2-phenyl-1H-quinolin-4-one \| 6-methyl-2-p...) Show SMILES Cc1ccc2nc(cc(O)c2c1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM31770 (Exelderm \| Sulconazole Nitrate \| cid_65495 \| sulco...) Show SMILES Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM37510 (6-methyl-2-phenyl-1H-quinolin-4-one \| 6-methyl-2-p...) Show SMILES Cc1ccc2nc(cc(O)c2c1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211054 (5-bromo-N-(naphthalen-1-yl)furan-2-carboxamide \| C...) Show SMILES Brc1ccc(o1)C(=O)Nc1cccc2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211051 (2-(perfluorobenzylthio)-3aH-benzo[d]imidazole \| CH...) Show SMILES Fc1c(F)c(F)c(CSc2nc3ccccc3[nH]2)c(F)c1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM31774 (CHEMBL104 \| Canesten \| Clotrimazole \| Lotrimin \| M...) Show SMILES Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211054 (5-bromo-N-(naphthalen-1-yl)furan-2-carboxamide \| C...) Show SMILES Brc1ccc(o1)C(=O)Nc1cccc2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50211051 (2-(perfluorobenzylthio)-3aH-benzo[d]imidazole \| CH...) Show SMILES Fc1c(F)c(F)c(CSc2nc3ccccc3[nH]2)c(F)c1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergent				J Med Chem 50: 2385-90 (2007) Article DOI: 10.1021/jm061317y BindingDB Entry DOI: 10.7270/Q2QC035D
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit (Saccharomyces cerevisiae (strain ATCC 204508 / S28...)	BDBM50482421 (TERAIODOPHENOLPHATHALIN) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells				Nat Chem Biol 4: 197-9 (2008) Article DOI: 10.1038/nchembio.65 BindingDB Entry DOI: 10.7270/Q2028VD2
University of California San Francisco Curated by ChEMBL					More data for this Ligand-Target Pair