| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50211053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_434808 (CHEMBL917036) |
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| IC50 | 40000±n/a nM |
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| Citation |  Feng, BY; Simeonov, A; Jadhav, A; Babaoglu, K; Inglese, J; Shoichet, BK; Austin, CP A high-throughput screen for aggregation-based inhibition in a large compound library. J Med Chem50:2385-90 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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| BDBM50211053 |
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| n/a |
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| Name | BDBM50211053 |
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| Synonyms: | CHEMBL226664 | N-{4-[3,4-bis(furan-2-amido)phenoxy]phenyl}furan-2-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C27H19N3O7 |
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| Mol. Mass. | 497.4557 |
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| SMILES | O=C(Nc1ccc(Oc2ccc(NC(=O)c3ccco3)c(NC(=O)c3ccco3)c2)cc1)c1ccco1 |
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| Structure | 
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