Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180790 (US8865745, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM60633 (US8865745, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.95 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180793 (US8865745, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180779 (US8865745, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.13 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM60635 (US8865745, 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.37 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180795 (US8865745, 20) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.75 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM60634 (US8865745, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.89 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180780 (US8865745, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.13 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180787 (US8865745, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.32 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180791 (US8865745, 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180789 (US8865745, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 16.2 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180781 (US8865745, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 17.8 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180782 (US8865745, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 18.2 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180785 (US8865745, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 22.4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180792 (US8865745, 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 33.1 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180794 (US8865745, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 33.1 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180788 (US8865745, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 34.7 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180783 (US8865745, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 70.8 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM180784 (US8865745, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 145 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda GmbH US Patent | Assay Description PDE4B1 activity was inhibited by the compounds according to the invention in a modified SPA (scintillation proximity assay) test, supplied by Amersha... | US Patent US8865745 (2014) BindingDB Entry DOI: 10.7270/Q2XK8DBB | |||||||||||
More data for this Ligand-Target Pair |