Compile Data Set for Download or QSAR

Found 46 hits with Last Name = 'fitzsimmons' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000534 (2-Phenethyl-6-[3-(pyridin-4-ylsulfanyl)-propyl]-2,...) Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1CCCSc1ccncc1 Show InChI InChI=1S/C24H25NO2S/c26-23-16-20-15-21(9-8-18-5-2-1-3-6-18)27-24(20)17-19(23)7-4-14-28-22-10-12-25-13-11-22/h1-3,5-6,10-13,16-17,21,26H,4,7-9,14-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000536 (6-Allyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol | ...) Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1CC=C Show InChI InChI=1S/C19H20O2/c1-2-6-15-13-19-16(12-18(15)20)11-17(21-19)10-9-14-7-4-3-5-8-14/h2-5,7-8,12-13,17,20H,1,6,9-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280965 (4-Phenyl-7-(5-phenyl-pyridin-2-ylmethoxy)-3H-napht...) Show SMILES O=C1OCc2c1cc1cc(OCc3ccc(cn3)-c3ccccc3)ccc1c2-c1ccccc1 Show InChI InChI=1S/C30H21NO3/c32-30-27-16-23-15-25(33-18-24-12-11-22(17-31-24)20-7-3-1-4-8-20)13-14-26(23)29(28(27)19-34-30)21-9-5-2-6-10-21/h1-17H,18-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000526 (2-Phenethyl-6-(3-phenoxy-propyl)-2,3-dihydro-benzo...) Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1CCCOc1ccccc1 Show InChI InChI=1S/C25H26O3/c26-24-17-21-16-23(14-13-19-8-3-1-4-9-19)28-25(21)18-20(24)10-7-15-27-22-11-5-2-6-12-22/h1-6,8-9,11-12,17-18,23,26H,7,10,13-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000551 (4-Allyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol | ...) Show SMILES Oc1ccc2OC(CCc3ccccc3)Cc2c1CC=C Show InChI InChI=1S/C19H20O2/c1-2-6-16-17-13-15(21-19(17)12-11-18(16)20)10-9-14-7-4-3-5-8-14/h2-5,7-8,11-12,15,20H,1,6,9-10,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000531 (2-(4-Methoxy-benzyl)-3-methyl-6-propyl-2,3-dihydro...) Show SMILES CCCc1cc2OC(Cc3ccc(OC)cc3)C(C)c2cc1O Show InChI InChI=1S/C20H24O3/c1-4-5-15-11-20-17(12-18(15)21)13(2)19(23-20)10-14-6-8-16(22-3)9-7-14/h6-9,11-13,19,21H,4-5,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000535 (3,3-Dimethyl-2-phenethyl-6-(3-phenoxy-propyl)-2,3-...) Show SMILES CC1(C)C(CCc2ccccc2)Oc2cc(CCCOc3ccccc3)c(O)cc12 Show InChI InChI=1S/C27H30O3/c1-27(2)23-19-24(28)21(12-9-17-29-22-13-7-4-8-14-22)18-25(23)30-26(27)16-15-20-10-5-3-6-11-20/h3-8,10-11,13-14,18-19,26,28H,9,12,15-17H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280968 (4-(3-Methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one ...) Show SMILES COc1cccc(c1)-c1c2COC(=O)c2cc2ccccc12 Show InChI InChI=1S/C19H14O3/c1-21-14-7-4-6-13(9-14)18-15-8-3-2-5-12(15)10-16-17(18)11-22-19(16)20/h2-10H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000542 (4-[3-(5-Hydroxy-2-phenethyl-2,3-dihydro-benzofuran...) Show SMILES OC(=O)c1ccc(OCCCc2cc3OC(CCc4ccccc4)Cc3cc2O)cc1 Show InChI InChI=1S/C26H26O5/c27-24-16-21-15-23(11-8-18-5-2-1-3-6-18)31-25(21)17-20(24)7-4-14-30-22-12-9-19(10-13-22)26(28)29/h1-3,5-6,9-10,12-13,16-17,23,27H,4,7-8,11,14-15H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000538 (3,3-Dimethyl-6-propyl-2-[2-(pyridin-2-ylsulfanyl)-...) Show SMILES CCCc1cc2OC(CCSc3ccccn3)C(C)(C)c2cc1O Show InChI InChI=1S/C20H25NO2S/c1-4-7-14-12-17-15(13-16(14)22)20(2,3)18(23-17)9-11-24-19-8-5-6-10-21-19/h5-6,8,10,12-13,18,22H,4,7,9,11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000527 (6-[3-(Benzothiazol-2-ylsulfanyl)-propyl]-2-pheneth...) Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1CCCSc1nc2ccccc2s1 Show InChI InChI=1S/C26H25NO2S2/c28-23-16-20-15-21(13-12-18-7-2-1-3-8-18)29-24(20)17-19(23)9-6-14-30-26-27-22-10-4-5-11-25(22)31-26/h1-5,7-8,10-11,16-17,21,28H,6,9,12-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000537 (2-Phenethyl-4-propyl-6-{3-[4-(5H-tetrazol-5-yl)-ph...) Show SMILES CCCc1c2CC(CCc3ccccc3)Oc2cc(CCCOc2ccc(cc2)-c2nnn[nH]2)c1O Show InChI InChI=1S/C29H32N4O3/c1-2-7-25-26-19-24(14-11-20-8-4-3-5-9-20)36-27(26)18-22(28(25)34)10-6-17-35-23-15-12-21(13-16-23)29-30-32-33-31-29/h3-5,8-9,12-13,15-16,18,24,34H,2,6-7,10-11,14,17,19H2,1H3,(H,30,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000533 (6-Benzyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol |...) Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1Cc1ccccc1 Show InChI InChI=1S/C23H22O2/c24-22-15-20-14-21(12-11-17-7-3-1-4-8-17)25-23(20)16-19(22)13-18-9-5-2-6-10-18/h1-10,15-16,21,24H,11-14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000545 (8-[3-(5-Hydroxy-2-phenethyl-2,3-dihydro-benzofuran...) Show SMILES COc1nc2c(SCCCc3cc4OC(CCc5ccccc5)Cc4cc3O)cccc2cc1C(O)=O Show InChI InChI=1S/C30H29NO5S/c1-35-29-24(30(33)34)16-21-9-5-11-27(28(21)31-29)37-14-6-10-20-18-26-22(17-25(20)32)15-23(36-26)13-12-19-7-3-2-4-8-19/h2-5,7-9,11,16-18,23,32H,6,10,12-15H2,1H3,(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000552 (2-[2-(4-Chloro-phenyl)-ethyl]-6-(3-phenoxy-propyl)...) Show SMILES Oc1cc2CC(CCc3ccc(Cl)cc3)Oc2cc1CCCOc1ccccc1 Show InChI InChI=1S/C25H25ClO3/c26-21-11-8-18(9-12-21)10-13-23-15-20-16-24(27)19(17-25(20)29-23)5-4-14-28-22-6-2-1-3-7-22/h1-3,6-9,11-12,16-17,23,27H,4-5,10,13-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000524 (6-Allyl-2-[2-(4-methoxy-phenyl)-ethyl]-3,3-dimethy...) Show SMILES COc1ccc(CCC2Oc3cc(CC=C)c(O)cc3C2(C)C)cc1 Show InChI InChI=1S/C22H26O3/c1-5-6-16-13-20-18(14-19(16)23)22(2,3)21(25-20)12-9-15-7-10-17(24-4)11-8-15/h5,7-8,10-11,13-14,21,23H,1,6,9,12H2,2-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000528 (1-{2-Hydroxy-4-[3-(5-hydroxy-2-phenethyl-2,3-dihyd...) Show SMILES CCCc1c(OCCCc2cc3OC(CCc4ccccc4)Cc3cc2O)ccc(C(C)=O)c1O Show InChI InChI=1S/C30H34O5/c1-3-8-26-28(15-14-25(20(2)31)30(26)33)34-16-7-11-22-19-29-23(18-27(22)32)17-24(35-29)13-12-21-9-5-4-6-10-21/h4-6,9-10,14-15,18-19,24,32-33H,3,7-8,11-13,16-17H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280961 (9-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...) Show SMILES O=C1OCc2c1cc1cc3OCOc3cc1c2-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H12O6/c21-20-13-3-11-5-17-18(26-9-25-17)6-12(11)19(14(13)7-22-20)10-1-2-15-16(4-10)24-8-23-15/h1-6H,7-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against LTB4 in human PMN				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280963 (4-Phenyl-7-(quinolin-2-ylmethoxy)-3H-naphtho[2,3-c...) Show SMILES O=C1OCc2c1cc1cc(OCc3ccc4ccccc4n3)ccc1c2-c1ccccc1 Show InChI InChI=1S/C28H19NO3/c30-28-24-15-20-14-22(31-16-21-11-10-18-6-4-5-9-26(18)29-21)12-13-23(20)27(25(24)17-32-28)19-7-2-1-3-8-19/h1-15H,16-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000544 (3,3-Dimethyl-2-[2-(4-methylsulfanyl-phenyl)-ethyl]...) Show SMILES CCCc1cc2OC(CCc3ccc(SC)cc3)C(C)(C)c2cc1O Show InChI InChI=1S/C22H28O2S/c1-5-6-16-13-20-18(14-19(16)23)22(2,3)21(24-20)12-9-15-7-10-17(25-4)11-8-15/h7-8,10-11,13-14,21,23H,5-6,9,12H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280959 (7-Benzyloxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one ...) Show SMILES O=C1OCc2c1cc1cc(OCc3ccccc3)ccc1c2-c1ccccc1 Show InChI InChI=1S/C25H18O3/c26-25-22-14-19-13-20(27-15-17-7-3-1-4-8-17)11-12-21(19)24(23(22)16-28-25)18-9-5-2-6-10-18/h1-14H,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000525 (2-Phenethyl-6-(3-phenoxy-propyl)-4-propyl-2,3-dihy...) Show SMILES CCCc1c2CC(CCc3ccccc3)Oc2cc(CCCOc2ccccc2)c1O Show InChI InChI=1S/C28H32O3/c1-2-10-25-26-20-24(17-16-21-11-5-3-6-12-21)31-27(26)19-22(28(25)29)13-9-18-30-23-14-7-4-8-15-23/h3-8,11-12,14-15,19,24,29H,2,9-10,13,16-18,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280979 (9-Phenyl-8H-furo[3',4':6,7]naphtho[2,3-d][1,3]diox...) Show SMILES O=C1OCc2c1cc1cc3OCOc3cc1c2-c1ccccc1 Show InChI InChI=1S/C19H12O4/c20-19-14-6-12-7-16-17(23-10-22-16)8-13(12)18(15(14)9-21-19)11-4-2-1-3-5-11/h1-8H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000532 (6-Allyl-2-(4-methoxy-benzyl)-3,3-dimethyl-2,3-dihy...) Show SMILES COc1ccc(CC2Oc3cc(CC=C)c(O)cc3C2(C)C)cc1 Show InChI InChI=1S/C21H24O3/c1-5-6-15-12-19-17(13-18(15)22)21(2,3)20(24-19)11-14-7-9-16(23-4)10-8-14/h5,7-10,12-13,20,22H,1,6,11H2,2-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280962 (7-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...) Show SMILES COc1ccc2c(c3COC(=O)c3cc2c1)-c1ccccc1 Show InChI InChI=1S/C19H14O3/c1-21-14-7-8-15-13(9-14)10-16-17(11-22-19(16)20)18(15)12-5-3-2-4-6-12/h2-10H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280974 (5-Benzo[1,3]dioxol-5-yl-6,8-dihydro-furo[3',4':6,7...) Show SMILES C1Oc2ccc(cc2O1)-c1c2COCc2cc2cc3OCOc3cc12 Show InChI InChI=1S/C20H14O5/c1-2-16-17(23-9-22-16)4-11(1)20-14-6-19-18(24-10-25-19)5-12(14)3-13-7-21-8-15(13)20/h1-6H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280966 (4-Phenyl-3H-naphtho[2,3-c]furan-1-one | CHEMBL6189...) Show SMILES O=C1OCc2c1cc1ccccc1c2-c1ccccc1 Show InChI InChI=1S/C18H12O2/c19-18-15-10-13-8-4-5-9-14(13)17(16(15)11-20-18)12-6-2-1-3-7-12/h1-10H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280976 (5-Benzo[1,3]dioxol-5-yl-6,7-dimethyl-naphtho[2,3-d...) Show SMILES Cc1cc2cc3OCOc3cc2c(c1C)-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H16O4/c1-11-5-14-7-18-19(24-10-23-18)8-15(14)20(12(11)2)13-3-4-16-17(6-13)22-9-21-16/h3-8H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280971 (5-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...) Show SMILES O=C1OCc2cc3cc4OCOc4cc3c(c12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H12O6/c21-20-19-12(7-22-20)3-11-5-16-17(26-9-25-16)6-13(11)18(19)10-1-2-14-15(4-10)24-8-23-14/h1-6H,7-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280970 (4-Benzo[1,3]dioxol-5-yl-3H-naphtho[2,3-c]furan-1-o...) Show SMILES O=C1OCc2c1cc1ccccc1c2-c1ccc2OCOc2c1 Show InChI InChI=1S/C19H12O4/c20-19-14-7-11-3-1-2-4-13(11)18(15(14)9-21-19)12-5-6-16-17(8-12)23-10-22-16/h1-8H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280967 (5-Benzo[1,3]dioxol-5-yl-5,9-dihydro-furo[3',4':6,7...) Show SMILES C1Oc2ccc(cc2O1)C1c2cocc2Cc2cc3OCOc3cc12 Show InChI InChI=1S/C20H14O5/c1-2-16-17(23-9-22-16)4-11(1)20-14-6-19-18(24-10-25-19)5-12(14)3-13-7-21-8-15(13)20/h1-2,4-8,20H,3,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280977 (4-Phenyl-5H-6-oxa-1-thia-s-indacen-7-one | CHEMBL6...) Show SMILES O=C1OCc2c1cc1sccc1c2-c1ccccc1 Show InChI InChI=1S/C16H10O2S/c17-16-12-8-14-11(6-7-19-14)15(13(12)9-18-16)10-4-2-1-3-5-10/h1-8H,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280961 (9-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...) Show SMILES O=C1OCc2c1cc1cc3OCOc3cc1c2-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H12O6/c21-20-13-3-11-5-17-18(26-9-25-17)6-12(11)19(14(13)7-22-20)10-1-2-15-16(4-10)24-8-23-15/h1-6H,7-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of human recombinant 5-lipoxygenase enzyme				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280964 (5-Benzo[1,3]dioxol-5-yl-furo[3',4':6,7]naphtho[2,3...) Show SMILES O=C1OC(=O)c2c1cc1cc3OCOc3cc1c2-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H10O7/c21-19-12-3-10-5-15-16(26-8-25-15)6-11(10)17(18(12)20(22)27-19)9-1-2-13-14(4-9)24-7-23-13/h1-6H,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280978 (6-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...) Show SMILES COc1ccc2cc3C(=O)OCc3c(-c3ccccc3)c2c1 Show InChI InChI=1S/C19H14O3/c1-21-14-8-7-13-9-16-17(11-22-19(16)20)18(15(13)10-14)12-5-3-2-4-6-12/h2-10H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50240576 (4-Benzo[1,3]dioxol-5-yl-6,7-dimethoxy-3H-naphtho[2...) Show SMILES COc1cc2cc3C(=O)OCc3c(-c3ccc4OCOc4c3)c2cc1OC Show InChI InChI=1S/C21H16O6/c1-23-17-7-12-5-14-15(9-25-21(14)22)20(13(12)8-18(17)24-2)11-3-4-16-19(6-11)27-10-26-16/h3-8H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280973 (4-(4-Methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one ...) Show SMILES COc1ccc(cc1)-c1c2COC(=O)c2cc2ccccc12 Show InChI InChI=1S/C19H14O3/c1-21-14-8-6-12(7-9-14)18-15-5-3-2-4-13(15)10-16-17(18)11-22-19(16)20/h2-10H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50000546 (3,4,5,6-Tetrahydroxy-tetrahydro-pyran-2-carboxylic...) Show SMILES CCc1ccccc1C1Cc2cc(OC(=O)C3O[C@@H](O)[C@H](O)[C@@H](O)[C@H]3O)c(CCCOc3ccccc3)cc2O1 Show InChI InChI=1S/C31H34O9/c1-2-18-9-6-7-13-22(18)25-17-20-16-23(39-31(36)29-27(33)26(32)28(34)30(35)40-29)19(15-24(20)38-25)10-8-14-37-21-11-4-3-5-12-21/h3-7,9,11-13,15-16,25-30,32-35H,2,8,10,14,17H2,1H3/t25?,26-,27+,28+,29?,30+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against LTB4 in human PMN				J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280975 ((5-Benzo[1,3]dioxol-5-yl-7-hydroxymethyl-naphtho[2...) Show SMILES OCc1cc2cc3OCOc3cc2c(c1CO)-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H16O6/c21-7-13-3-12-5-18-19(26-10-25-18)6-14(12)20(15(13)8-22)11-1-2-16-17(4-11)24-9-23-16/h1-6,21-22H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280959 (7-Benzyloxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one ...) Show SMILES O=C1OCc2c1cc1cc(OCc3ccccc3)ccc1c2-c1ccccc1 Show InChI InChI=1S/C25H18O3/c26-25-22-14-19-13-20(27-15-17-7-3-1-4-8-17)11-12-21(19)24(23(22)16-28-25)18-9-5-2-6-10-18/h1-14H,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of human recombinant lipoxygenase enzyme				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280969 (4-Phenyl-3H-furo[3,4-g]isoquinolin-1-one | CHEMBL3...) Show SMILES O=C1OCc2c1cc1ccncc1c2-c1ccccc1 Show InChI InChI=1S/C17H11NO2/c19-17-13-8-12-6-7-18-9-14(12)16(15(13)10-20-17)11-4-2-1-3-5-11/h1-9H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280972 (4-Pyridin-4-yl-3H-naphtho[2,3-c]furan-1-one | CHEM...) Show SMILES O=C1OCc2c1cc1ccccc1c2-c1ccncc1 Show InChI InChI=1S/C17H11NO2/c19-17-14-9-12-3-1-2-4-13(12)16(15(14)10-20-17)11-5-7-18-8-6-11/h1-9H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280980 (9-Benzo[1,3]dioxol-5-yl-7,8-dihydro-1,3-dioxa-7-az...) Show SMILES O=C1NCc2c1cc1cc3OCOc3cc1c2-c1ccc2OCOc2c1 Show InChI InChI=1S/C20H13NO5/c22-20-13-3-11-5-17-18(26-9-25-17)6-12(11)19(14(13)7-21-20)10-1-2-15-16(4-10)24-8-23-15/h1-6H,7-9H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280960 (9-(3,4-Dimethoxy-phenyl)-8H-furo[3',4':6,7]naphtho...) Show SMILES COc1ccc(cc1OC)-c1c2COC(=O)c2cc2cc3OCOc3cc12 Show InChI InChI=1S/C21H16O6/c1-23-16-4-3-11(6-17(16)24-2)20-13-8-19-18(26-10-27-19)7-12(13)5-14-15(20)9-25-21(14)22/h3-8H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair