BindingDB PrimarySearch

Found 10 hits with Last Name = 'flint' and Initial = 'op'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	35.6	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.60	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.20	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20879 (C-aryl glucoside, 5 \| CHEMBL429911 \| N-ethyl-2,6-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM20880 ((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.39E+3	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	211	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>8.00E+3	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM20879 (C-aryl glucoside, 5 \| CHEMBL429911 \| N-ethyl-2,6-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>8.00E+3	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20880 ((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	7.2	22
Bristol-Myers Squibb Company					Assay Description Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...				J Med Chem 51: 1145-9 (2008) Article DOI: 10.1021/jm701272q BindingDB Entry DOI: 10.7270/Q2PN93X4
Bristol-Myers Squibb Company					More data for this Ligand-Target Pair				3D Structure (crystal)