Found 188 hits with Last Name = 'flipo' and Initial = 'm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neprilysin
(Homo sapiens (Human)) | BDBM21641
(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description Inhibition of human NEP-mediated amyloid beta hydrolysis |
Eur J Med Chem 79: 184-93 (2014)
Article DOI: 10.1016/j.ejmech.2014.04.009 BindingDB Entry DOI: 10.7270/Q27H1M34 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206554
(CHEMBL219777 | N-(4-fluoro-benzyl)-N'-hydroxy-2-[1...)Show InChI InChI=1S/C17H15FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-10,23H,11H2,(H,19,21)(H,20,22)/b15-10- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM21642
((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)Show InChI InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description Inhibition of human ACE-mediated amyloid beta hydrolysis |
Eur J Med Chem 79: 184-93 (2014)
Article DOI: 10.1016/j.ejmech.2014.04.009 BindingDB Entry DOI: 10.7270/Q27H1M34 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602370
(CHEMBL5186518)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(OC(F)(F)F)cc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602369
(CHEMBL5201484)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(cc1)C(F)(F)F)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206558
(CHEMBL375521 | N-hydroxy-N'-(4-phenyl-butyl)-2-[1-...)Show InChI InChI=1S/C20H22N2O3/c23-19(21-14-8-7-11-16-9-3-1-4-10-16)18(20(24)22-25)15-17-12-5-2-6-13-17/h1-6,9-10,12-13,15,25H,7-8,11,14H2,(H,21,23)(H,22,24)/b18-15- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602368
(CHEMBL5171834)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(Cl)cc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50131276
(CHEMBL328470 | N-(3-{4-[3-(7-Chloro-quinolin-4-yla...)Show SMILES CC(C)CN(CCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)C(=O)CC(=O)NO Show InChI InChI=1S/C26H39ClN6O3/c1-20(2)19-33(26(35)18-25(34)30-36)12-4-11-32-15-13-31(14-16-32)10-3-8-28-23-7-9-29-24-17-21(27)5-6-22(23)24/h5-7,9,17,20,36H,3-4,8,10-16,18-19H2,1-2H3,(H,28,29)(H,30,34) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 2
Curated by ChEMBL
| Assay Description Inhibitory activity against mammalian Aminopeptidase N (APN) |
Bioorg Med Chem Lett 13: 2659-62 (2003)
BindingDB Entry DOI: 10.7270/Q20G3KPK |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description Inhibition of human erythrocyte carbonic anhydrase-2 assessed as hydrolysis of 4-nitrophenylacetate |
J Med Chem 55: 10909-17 (2012)
Article DOI: 10.1021/jm301506h BindingDB Entry DOI: 10.7270/Q2Z60Q6R |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602371
(CHEMBL5202255)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(nc1)C(F)(F)F)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602369
(CHEMBL5201484)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(cc1)C(F)(F)F)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602370
(CHEMBL5186518)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(OC(F)(F)F)cc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206550
(2-benzyl-N-hydroxy-N'-(2-methyl-benzyl)-malonamide...)Show InChI InChI=1S/C18H20N2O3/c1-13-7-5-6-10-15(13)12-19-17(21)16(18(22)20-23)11-14-8-3-2-4-9-14/h2-10,16,23H,11-12H2,1H3,(H,19,21)(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602368
(CHEMBL5171834)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(Cl)cc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50197503
(CHEMBL425291 | N-hydroxy-2-isobutyl-N'-(3-phenoxy-...)Show InChI InChI=1S/C20H24N2O4/c1-14(2)11-18(20(24)22-25)19(23)21-13-15-7-6-10-17(12-15)26-16-8-4-3-5-9-16/h3-10,12,14,18,25H,11,13H2,1-2H3,(H,21,23)(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50197497
(2-benzyl-N-hydroxy-N'-(4-phenyl-butyl)-malonamide ...)Show InChI InChI=1S/C20H24N2O3/c23-19(21-14-8-7-11-16-9-3-1-4-10-16)18(20(24)22-25)15-17-12-5-2-6-13-17/h1-6,9-10,12-13,18,25H,7-8,11,14-15H2,(H,21,23)(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206556
(2-Benzyl-N-(4-fluoro-benzyl)-N'-hydroxy-malonamide...)Show InChI InChI=1S/C17H17FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase NdhA
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602370
(CHEMBL5186518)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(OC(F)(F)F)cc1)C2)C(C)C |r| | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase NdhA
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602369
(CHEMBL5201484)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(cc1)C(F)(F)F)C2)C(C)C |r| | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50197498
(CHEMBL220311 | N-hydroxy-2-isobutyl-N'-(4-phenyl-b...)Show InChI InChI=1S/C17H26N2O3/c1-13(2)12-15(17(21)19-22)16(20)18-11-7-6-10-14-8-4-3-5-9-14/h3-5,8-9,13,15,22H,6-7,10-12H2,1-2H3,(H,18,20)(H,19,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lille 2
Curated by ChEMBL
| Assay Description Inhibition of microsomal neural aminopeptidase in pig kidney |
Bioorg Med Chem 15: 63-76 (2006)
Article DOI: 10.1016/j.bmc.2006.10.010 BindingDB Entry DOI: 10.7270/Q23F4P9V |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602371
(CHEMBL5202255)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(nc1)C(F)(F)F)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206547
(CHEMBL374479 | N-hydroxy-2-isobutyl-N'-naphthalen-...)Show InChI InChI=1S/C18H22N2O3/c1-12(2)10-16(18(22)20-23)17(21)19-11-14-8-5-7-13-6-3-4-9-15(13)14/h3-9,12,16,23H,10-11H2,1-2H3,(H,19,21)(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase NdhA
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602368
(CHEMBL5171834)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(Cl)cc1)C2)C(C)C |r| | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
Insulin-degrading enzyme
(Homo sapiens (Human)) | BDBM50005641
(CHEMBL3235416)Show SMILES CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN(CCCc1ccccc1)CC(O)=O |r| Show InChI InChI=1S/C20H27N5O4/c1-21-20(29)17(10-16-11-22-14-23-16)24-18(26)12-25(13-19(27)28)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,11,14,17H,5,8-10,12-13H2,1H3,(H,21,29)(H,22,23)(H,24,26)(H,27,28)/t17-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p... |
Eur J Med Chem 79: 184-93 (2014)
Article DOI: 10.1016/j.ejmech.2014.04.009 BindingDB Entry DOI: 10.7270/Q27H1M34 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206543
(2-benzyl-N-hydroxy-N'-naphthalen-1-ylmethyl-malona...)Show InChI InChI=1S/C21H20N2O3/c24-20(19(21(25)23-26)13-15-7-2-1-3-8-15)22-14-17-11-6-10-16-9-4-5-12-18(16)17/h1-12,19,26H,13-14H2,(H,22,24)(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206551
(CHEMBL376198 | N-hydroxy-2-isobutyl-N'-(1,2,3,4-te...)Show InChI InChI=1S/C16H22N2O3/c1-11(2)10-13(15(19)17-21)16(20)18-9-5-7-12-6-3-4-8-14(12)18/h3-4,6,8,11,13,21H,5,7,9-10H2,1-2H3,(H,17,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50062474
(2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...)Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50062453
(2-Benzyl-N-hydroxy-N'-(3-phenyl-propyl)-malonamide...)Show InChI InChI=1S/C19H22N2O3/c22-18(20-13-7-12-15-8-3-1-4-9-15)17(19(23)21-24)14-16-10-5-2-6-11-16/h1-6,8-11,17,24H,7,12-14H2,(H,20,22)(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206552
(2-(3-phenoxybenzyl)-N1-(4-chlorobenzyl)-N3-hydroxy...)Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN2O4/c24-18-11-9-16(10-12-18)15-25-22(27)21(23(28)26-29)14-17-5-4-8-20(13-17)30-19-6-2-1-3-7-19/h1-13,21,29H,14-15H2,(H,25,27)(H,26,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50197501
(2-(3-phenoxybenzyl)-N1-benzyl-N3-hydroxymalonamide...)Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H22N2O4/c26-22(24-16-17-8-3-1-4-9-17)21(23(27)25-28)15-18-10-7-13-20(14-18)29-19-11-5-2-6-12-19/h1-14,21,28H,15-16H2,(H,24,26)(H,25,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 164 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206546
(2-benzyl-N-(4-chloro-benzyl)-N'-hydroxy-malonamide...)Show InChI InChI=1S/C17H17ClN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602367
(CHEMBL5206556)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(OC)cc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206557
(2-benzyl-3-(4-benzyl-piperidin-1-yl)-N-hydroxy-3-o...)Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H26N2O3/c25-21(23-27)20(16-18-9-5-2-6-10-18)22(26)24-13-11-19(12-14-24)15-17-7-3-1-4-8-17/h1-10,19-20,27H,11-16H2,(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50197505
(2-(3-phenoxybenzyl)-N1-hydroxy-N3-(4-phenylbutyl)m...)Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCCCCc1ccccc1 Show InChI InChI=1S/C26H28N2O4/c29-25(27-17-8-7-12-20-10-3-1-4-11-20)24(26(30)28-31)19-21-13-9-16-23(18-21)32-22-14-5-2-6-15-22/h1-6,9-11,13-16,18,24,31H,7-8,12,17,19H2,(H,27,29)(H,28,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206566
(2-(3-phenoxybenzyl)-N1-(4-(trifluoromethyl)benzyl)...)Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H21F3N2O4/c25-24(26,27)18-11-9-16(10-12-18)15-28-22(30)21(23(31)29-32)14-17-5-4-8-20(13-17)33-19-6-2-1-3-7-19/h1-13,21,32H,14-15H2,(H,28,30)(H,29,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 231 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206564
(2-(3-phenoxybenzyl)-3-(4-benzylpiperidin-1-yl)-N-h...)Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C28H30N2O4/c31-27(29-33)26(20-23-10-7-13-25(19-23)34-24-11-5-2-6-12-24)28(32)30-16-14-22(15-17-30)18-21-8-3-1-4-9-21/h1-13,19,22,26,33H,14-18,20H2,(H,29,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 248 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206545
(2-benzyl-3-(3,4-dihydro-1H-isoquinolin-2-yl)-N-hyd...)Show InChI InChI=1S/C19H20N2O3/c22-18(20-24)17(12-14-6-2-1-3-7-14)19(23)21-11-10-15-8-4-5-9-16(15)13-21/h1-9,17,24H,10-13H2,(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM23971
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 284 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 2
Curated by ChEMBL
| Assay Description Inhibitory activity for Plasmodium falciparum Zinc aminopeptidase |
Bioorg Med Chem Lett 13: 2659-62 (2003)
BindingDB Entry DOI: 10.7270/Q20G3KPK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Type II NADH:quinone oxidoreductase NdhA
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602371
(CHEMBL5202255)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccc(nc1)C(F)(F)F)C2)C(C)C |r| | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206555
(2-[1-Phenyl-meth-(Z)-ylidene]-malonic Acid Monoeth...)Show InChI InChI=1S/C17H15FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-10,23H,11H2,(H,19,21)(H,20,22)/b15-10+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602366
(CHEMBL5182198)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccccc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
HTH-type transcriptional regulator EthR
(Mycobacterium tuberculosis) | BDBM50363052
(CHEMBL1946956)Show SMILES FC(F)(F)CCCC(=O)N1CCC(CC1)c1nc(no1)-c1nccs1 Show InChI InChI=1S/C15H17F3N4O2S/c16-15(17,18)5-1-2-11(23)22-7-3-10(4-8-22)13-20-12(21-24-13)14-19-6-9-25-14/h6,9-10H,1-5,7-8H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assay |
J Med Chem 55: 68-83 (2012)
Article DOI: 10.1021/jm200825u BindingDB Entry DOI: 10.7270/Q2RX9CJW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50197495
(2-(4-benzyl-piperidine-1-carbonyl)-4-methyl-pentan...)Show InChI InChI=1S/C19H28N2O3/c1-14(2)12-17(18(22)20-24)19(23)21-10-8-16(9-11-21)13-15-6-4-3-5-7-15/h3-7,14,16-17,24H,8-13H2,1-2H3,(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 406 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50197503
(CHEMBL425291 | N-hydroxy-2-isobutyl-N'-(3-phenoxy-...)Show InChI InChI=1S/C20H24N2O4/c1-14(2)11-18(20(24)22-25)19(23)21-13-15-7-6-10-17(12-15)26-16-8-4-3-5-9-16/h3-10,12,14,18,25H,11,13H2,1-2H3,(H,21,23)(H,22,24) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 443 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of pig kidney microsomal APN |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50197503
(CHEMBL425291 | N-hydroxy-2-isobutyl-N'-(3-phenoxy-...)Show InChI InChI=1S/C20H24N2O4/c1-14(2)11-18(20(24)22-25)19(23)21-13-15-7-6-10-17(12-15)26-16-8-4-3-5-9-16/h3-10,12,14,18,25H,11,13H2,1-2H3,(H,21,23)(H,22,24) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 443 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lille 2
Curated by ChEMBL
| Assay Description Inhibition of microsomal neural aminopeptidase in pig kidney |
Bioorg Med Chem 15: 63-76 (2006)
Article DOI: 10.1016/j.bmc.2006.10.010 BindingDB Entry DOI: 10.7270/Q23F4P9V |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50197495
(2-(4-benzyl-piperidine-1-carbonyl)-4-methyl-pentan...)Show InChI InChI=1S/C19H28N2O3/c1-14(2)12-17(18(22)20-24)19(23)21-10-8-16(9-11-21)13-15-6-4-3-5-7-15/h3-7,14,16-17,24H,8-13H2,1-2H3,(H,20,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 452 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lille 2
Curated by ChEMBL
| Assay Description Inhibition of microsomal neural aminopeptidase in pig kidney |
Bioorg Med Chem 15: 63-76 (2006)
Article DOI: 10.1016/j.bmc.2006.10.010 BindingDB Entry DOI: 10.7270/Q23F4P9V |
More data for this Ligand-Target Pair | |
Type II NADH:quinone oxidoreductase Ndh
(Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50602366
(CHEMBL5182198)Show SMILES [H][C@]12CCC(=O)N3[C@H](CO[C@]13CCN(Cc1ccccc1)C2)C(C)C |r| | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01493 BindingDB Entry DOI: 10.7270/Q24F1VTT |
More data for this Ligand-Target Pair | |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50197494
(CHEMBL220253 | N-benzyl-N'-hydroxy-2-isobutyl-malo...)Show InChI InChI=1S/C14H20N2O3/c1-10(2)8-12(14(18)16-19)13(17)15-9-11-6-4-3-5-7-11/h3-7,10,12,19H,8-9H2,1-2H3,(H,15,17)(H,16,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 495 | n/a | n/a | n/a | n/a | n/a | n/a |
Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |
HTH-type transcriptional regulator EthR
(Mycobacterium tuberculosis) | BDBM50343344
(1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-o...)Show InChI InChI=1S/C17H17N3O2S2/c21-15(11-13-3-1-9-23-13)20-7-5-12(6-8-20)17-18-16(19-22-17)14-4-2-10-24-14/h1-4,9-10,12H,5-8,11H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay |
J Med Chem 54: 2994-3010 (2011)
Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
M1 family aminopeptidase
(Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM50206565
(2-(3-phenoxybenzyl)-N1-hydroxy-N3-(3-phenylpropyl)...)Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C25H26N2O4/c28-24(26-16-8-12-19-9-3-1-4-10-19)23(25(29)27-30)18-20-11-7-15-22(17-20)31-21-13-5-2-6-14-21/h1-7,9-11,13-15,17,23,30H,8,12,16,18H2,(H,26,28)(H,27,29) | PDB MMDB
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UniProtKB/SwissProt
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Inserm
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase |
J Med Chem 50: 1322-34 (2007)
Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3 |
More data for this Ligand-Target Pair | |