Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
M1 family aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-... | J Med Chem 54: 1655-66 (2011) Article DOI: 10.1021/jm101227t BindingDB Entry DOI: 10.7270/Q23X86ZX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
M1 family aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia)) | BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 284 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 2 Curated by ChEMBL | Assay Description Inhibitory activity for Plasmodium falciparum Zinc aminopeptidase | Bioorg Med Chem Lett 13: 2659-62 (2003) BindingDB Entry DOI: 10.7270/Q20G3KPK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |