Compile Data Set for Download or QSAR

Found 48 hits with Last Name = 'foucaud' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082020 (2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-17-6-1-2-7-19(17)31-15-5-3-4-13(10-15)21-22(29)16-9-8-14(25)11-18(16)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50007674 ((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...) Show SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082027 (2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...) Show SMILES Oc1c(-c2cccc(Oc3cccc(NC(=O)CCl)c3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-15-4-2-6-17(11-15)31-16-5-1-3-13(9-16)21-22(29)18-8-7-14(25)10-19(18)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C21H14ClNO3/c22-14-9-10-17-18(12-14)23-21(25)19(20(17)24)13-5-4-8-16(11-13)26-15-6-2-1-3-7-15/h1-12H,(H2,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082022 (2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinoli...) Show SMILES Oc1c(-c2cccc(NCCS(F)(=O)=O)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C17H14ClFN2O4S/c18-11-4-5-13-14(9-11)21-17(23)15(16(13)22)10-2-1-3-12(8-10)20-6-7-26(19,24)25/h1-5,8-9,20H,6-7H2,(H2,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082021 (4-Fluorosulfonyl-benzoic acid 7-chloro-2-oxo-3-(3-...) Show SMILES FS(=O)(=O)c1ccc(cc1)C(=O)Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C28H17ClFNO6S/c29-19-11-14-23-24(16-19)31-27(32)25(18-5-4-8-21(15-18)36-20-6-2-1-3-7-20)26(23)37-28(33)17-9-12-22(13-10-17)38(30,34)35/h1-16H,(H,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	24.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082024 (2-{2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quin...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3NCCS(F)(=O)=O)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H18ClFN2O5S/c24-15-8-9-17-19(13-15)27-23(29)21(22(17)28)14-4-3-5-16(12-14)32-20-7-2-1-6-18(20)26-10-11-33(25,30)31/h1-9,12-13,26H,10-11H2,(H2,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082016 (2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydr...) Show SMILES Oc1c(-c2cccc(NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C17H12Cl2N2O3/c18-8-14(22)20-11-3-1-2-9(6-11)15-16(23)12-5-4-10(19)7-13(12)21-17(15)24/h1-7H,8H2,(H,20,22)(H2,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082023 (7-Chloro-4-hydroxy-3-(3-isothiocyanato-phenyl)-1H-...) Show SMILES Oc1c(-c2cccc(c2)N=C=S)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C16H9ClN2O2S/c17-10-4-5-12-13(7-10)19-16(21)14(15(12)20)9-2-1-3-11(6-9)18-8-22/h1-7H,(H2,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377833 (CHEMBL413998) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(N)cc1 Show InChI InChI=1S/C21H26N2O/c1-16(21(24)19-7-9-20(22)10-8-19)23-13-11-18(12-14-23)15-17-5-3-2-4-6-17/h2-10,16,18H,11-15,22H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377825 (CHEMBL258032) Show SMILES OC(CN1CCC(Cc2ccccc2)CC1)c1ccc(O)cc1 |w:1.0| Show InChI InChI=1S/C20H25NO2/c22-19-8-6-18(7-9-19)20(23)15-21-12-10-17(11-13-21)14-16-4-2-1-3-5-16/h1-9,17,20,22-23H,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082025 (4-Hydroxy-7-isothiocyanato-3-(3-phenoxy-phenyl)-1H...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(ccc12)N=C=S Show InChI InChI=1S/C22H14N2O3S/c25-21-18-10-9-15(23-13-28)12-19(18)24-22(26)20(21)14-5-4-8-17(11-14)27-16-6-2-1-3-7-16/h1-12H,(H2,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	64.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377831 (CHEMBL255697) Show SMILES CC(C(O)c1ccc(N)cc1)N1CCC(Cc2ccccc2)CC1 |w:2.2,1.0| Show InChI InChI=1S/C21H28N2O/c1-16(21(24)19-7-9-20(22)10-8-19)23-13-11-18(12-14-23)15-17-5-3-2-4-6-17/h2-10,16,18,21,24H,11-15,22H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377831 (CHEMBL255697) Show SMILES CC(C(O)c1ccc(N)cc1)N1CCC(Cc2ccccc2)CC1 |w:2.2,1.0| Show InChI InChI=1S/C21H28N2O/c1-16(21(24)19-7-9-20(22)10-8-19)23-13-11-18(12-14-23)15-17-5-3-2-4-6-17/h2-10,16,18,21,24H,11-15,22H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377834 (CHEMBL401882) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C23H28N2O2/c1-17(23(27)21-8-10-22(11-9-21)24-18(2)26)25-14-12-20(13-15-25)16-19-6-4-3-5-7-19/h3-11,17,20H,12-16H2,1-2H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377828 (CHEMBL257783) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23NO2/c22-19-8-6-18(7-9-19)20(23)15-21-12-10-17(11-13-21)14-16-4-2-1-3-5-16/h1-9,17,22H,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377827 (CHEMBL257989) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)[N+]([O-])=O)CC1 Show InChI InChI=1S/C20H22N2O4/c23-19-7-3-17(4-8-19)20(24)14-21-11-9-16(10-12-21)13-15-1-5-18(6-2-15)22(25)26/h1-8,16,23H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082017 (2-Chloro-N-[7-chloro-2-oxo-3-(3-phenoxy-phenyl)-1,...) Show SMILES ClCC(=O)Nc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O3/c24-13-20(28)27-22-18-10-9-15(25)12-19(18)26-23(29)21(22)14-5-4-8-17(11-14)30-16-6-2-1-3-7-16/h1-12H,13H2,(H2,26,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377826 (CHEMBL402979) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377829 (CHEMBL255895) Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)C(=C)CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H24N2O3/c1-17(22(25)20-7-9-21(10-8-20)24(26)27)16-23-13-11-19(12-14-23)15-18-5-3-2-4-6-18/h2-10,19H,1,11-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082019 (2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(NC(=O)CCl)ccc12 Show InChI InChI=1S/C23H17ClN2O4/c24-13-20(27)25-15-9-10-18-19(12-15)26-23(29)21(22(18)28)14-5-4-8-17(11-14)30-16-6-2-1-3-7-16/h1-12H,13H2,(H,25,27)(H2,26,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	278	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082018 (CHEMBL276907 | Chloro-acetic acid 7-(2-chloro-acet...) Show SMILES ClCC(=O)Nc1ccc2c(OC(=O)CCl)c(-c3cccc(Oc4ccccc4)c3)c(=O)[nH]c2c1 Show InChI InChI=1S/C25H18Cl2N2O5/c26-13-21(30)28-16-9-10-19-20(12-16)29-25(32)23(24(19)34-22(31)14-27)15-5-4-8-18(11-15)33-17-6-2-1-3-7-17/h1-12H,13-14H2,(H,28,30)(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377832 (CHEMBL401688) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	493	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377830 (CHEMBL401806) Show SMILES COc1ccc(cc1)C(=O)C(=C)CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H27NO2/c1-18(23(25)21-8-10-22(26-2)11-9-21)17-24-14-12-20(13-15-24)16-19-6-4-3-5-7-19/h3-11,20H,1,12-17H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	527	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50377835 (CHEMBL256083) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(cc1)N=C=S Show InChI InChI=1S/C22H24N2OS/c1-17(22(25)20-7-9-21(10-8-20)23-16-26)24-13-11-19(12-14-24)15-18-5-3-2-4-6-18/h2-10,17,19H,11-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	679	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082026 (4-Hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1,2-dihydro-q...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(ccc12)[N+]#N Show InChI InChI=1S/C21H13N3O3/c22-24-14-9-10-17-18(12-14)23-21(26)19(20(17)25)13-5-4-8-16(11-13)27-15-6-2-1-3-7-15/h1-12H,(H-,23,25,26)/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C21H14ClNO3/c22-14-9-10-17-18(12-14)23-21(25)19(20(17)24)13-5-4-8-16(11-13)26-15-6-2-1-3-7-15/h1-12H,(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082020 (2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-17-6-1-2-7-19(17)31-15-5-3-4-13(10-15)21-22(29)16-9-8-14(25)11-18(16)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082024 (2-{2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quin...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3NCCS(F)(=O)=O)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H18ClFN2O5S/c24-15-8-9-17-19(13-15)27-23(29)21(22(17)28)14-4-3-5-16(12-14)32-20-7-2-1-6-18(20)26-10-11-33(25,30)31/h1-9,12-13,26H,10-11H2,(H2,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082027 (2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...) Show SMILES Oc1c(-c2cccc(Oc3cccc(NC(=O)CCl)c3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-15-4-2-6-17(11-15)31-16-5-1-3-13(9-16)21-22(29)18-8-7-14(25)10-19(18)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50007674 ((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...) Show SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082016 (2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydr...) Show SMILES Oc1c(-c2cccc(NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C17H12Cl2N2O3/c18-8-14(22)20-11-3-1-2-9(6-11)15-16(23)12-5-4-10(19)7-13(12)21-17(15)24/h1-7H,8H2,(H,20,22)(H2,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082023 (7-Chloro-4-hydroxy-3-(3-isothiocyanato-phenyl)-1H-...) Show SMILES Oc1c(-c2cccc(c2)N=C=S)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C16H9ClN2O2S/c17-10-4-5-12-13(7-10)19-16(21)14(15(12)20)9-2-1-3-11(6-9)18-8-22/h1-7H,(H2,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082022 (2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinoli...) Show SMILES Oc1c(-c2cccc(NCCS(F)(=O)=O)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C17H14ClFN2O4S/c18-11-4-5-13-14(9-11)21-17(23)15(16(13)22)10-2-1-3-12(8-10)20-6-7-26(19,24)25/h1-5,8-9,20H,6-7H2,(H2,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082021 (4-Fluorosulfonyl-benzoic acid 7-chloro-2-oxo-3-(3-...) Show SMILES FS(=O)(=O)c1ccc(cc1)C(=O)Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C28H17ClFNO6S/c29-19-11-14-23-24(16-19)31-27(32)25(18-5-4-8-21(15-18)36-20-6-2-1-3-7-20)26(23)37-28(33)17-9-12-22(13-10-17)38(30,34)35/h1-16H,(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50377832 (CHEMBL401688) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50377826 (CHEMBL402979) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Homo sapiens (Human))	BDBM50377826 (CHEMBL402979) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082025 (4-Hydroxy-7-isothiocyanato-3-(3-phenoxy-phenyl)-1H...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(ccc12)N=C=S Show InChI InChI=1S/C22H14N2O3S/c25-21-18-10-9-15(23-13-28)12-19(18)24-22(26)20(21)14-5-4-8-17(11-14)27-16-6-2-1-3-7-16/h1-12H,(H2,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082019 (2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(NC(=O)CCl)ccc12 Show InChI InChI=1S/C23H17ClN2O4/c24-13-20(27)25-15-9-10-18-19(12-15)26-23(29)21(22(18)28)14-5-4-8-17(11-14)30-16-6-2-1-3-7-16/h1-12H,13H2,(H,25,27)(H2,26,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082018 (CHEMBL276907 | Chloro-acetic acid 7-(2-chloro-acet...) Show SMILES ClCC(=O)Nc1ccc2c(OC(=O)CCl)c(-c3cccc(Oc4ccccc4)c3)c(=O)[nH]c2c1 Show InChI InChI=1S/C25H18Cl2N2O5/c26-13-21(30)28-16-9-10-19-20(12-16)29-25(32)23(24(19)34-22(31)14-27)15-5-4-8-18(11-15)33-17-6-2-1-3-7-17/h1-12H,13-14H2,(H,28,30)(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50377830 (CHEMBL401806) Show SMILES COc1ccc(cc1)C(=O)C(=C)CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H27NO2/c1-18(23(25)21-8-10-22(26-2)11-9-21)17-24-14-12-20(13-15-24)16-19-6-4-3-5-7-19/h3-11,20H,1,12-17H2,2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50082017 (2-Chloro-N-[7-chloro-2-oxo-3-(3-phenoxy-phenyl)-1,...) Show SMILES ClCC(=O)Nc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O3/c24-13-20(28)27-22-18-10-9-15(25)12-19(18)26-23(29)21(22)14-5-4-8-17(11-14)30-16-6-2-1-3-7-16/h1-12H,13H2,(H2,26,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50377832 (CHEMBL401688) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren...				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50377826 (CHEMBL402979) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren...				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Homo sapiens (Human))	BDBM50377832 (CHEMBL401688) Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Homo sapiens (Human))	BDBM50377830 (CHEMBL401806) Show SMILES COc1ccc(cc1)C(=O)C(=C)CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H27NO2/c1-18(23(25)21-8-10-22(26-2)11-9-21)17-24-14-12-20(13-15-24)16-19-6-4-3-5-7-19/h3-11,20H,1,12-17H2,2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Homo sapiens (Human))	BDBM50377826 (CHEMBL402979) Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur de Strasbourg Curated by ChEMBL					Assay Description Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response				Bioorg Med Chem Lett 18: 2765-70 (2008) Article DOI: 10.1016/j.bmcl.2008.04.019 BindingDB Entry DOI: 10.7270/Q21C1XR4
					More data for this Ligand-Target Pair