Compile Data Set for Download or QSAR

Found 106 hits with Last Name = 'fraga-spano' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150572 (1-(2-Bromo-phenyl)-3-(2,4-dihydroxy-phenyl)-urea |...) Show SMILES Oc1ccc(NC(=O)Nc2ccccc2Br)c(O)c1 Show InChI InChI=1S/C13H11BrN2O3/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17)7-12(11)18/h1-7,17-18H,(H2,15,16,19)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150573 (1-{4-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenoxyme...) Show SMILES CN1CCN(COc2ccc(cc2)-c2cc(on2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C21H22ClN3O2/c1-24-10-12-25(13-11-24)15-26-19-8-4-16(5-9-19)20-14-21(27-23-20)17-2-6-18(22)7-3-17/h2-9,14H,10-13,15H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150561 (1-(3-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-phenox...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H26FN3O2/c1-26-12-14-27(15-13-26)11-2-16-28-21-9-5-19(6-10-21)23-17-22(25-29-23)18-3-7-20(24)8-4-18/h3-10,17H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150558 (1-(3-{4-[3-(4-Chloro-phenyl)-isoxazol-5-yl]-phenox...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C23H26ClN3O2/c1-26-12-14-27(15-13-26)11-2-16-28-21-9-5-19(6-10-21)23-17-22(25-29-23)18-3-7-20(24)8-4-18/h3-10,17H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150555 (1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2nc(no2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C22H25ClN4O2/c1-26-12-14-27(15-13-26)11-2-16-28-20-9-5-18(6-10-20)22-24-21(25-29-22)17-3-7-19(23)8-4-17/h3-10H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150563 (CHEMBL183061 | {4-[5-(4-Chloro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2O2/c1-21(2)12-22-16-9-5-13(6-10-16)17-11-18(23-20-17)14-3-7-15(19)8-4-14/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50471725 (CHEMBL327734) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cccc(O)c1O Show InChI InChI=1S/C22H16Cl2N2O3/c1-12-9-16(17(11-25)13-5-7-14(23)8-6-13)18(24)10-19(12)26-22(29)15-3-2-4-20(27)21(15)28/h2-10,17,27-28H,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150553 (1-Methyl-4-{3-[4-(3-phenyl-isoxazol-5-yl)-phenoxy]...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2ccccc2)CC1 Show InChI InChI=1S/C23H27N3O2/c1-25-13-15-26(16-14-25)12-5-17-27-21-10-8-20(9-11-21)23-18-22(24-28-23)19-6-3-2-4-7-19/h2-4,6-11,18H,5,12-17H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150559 (CHEMBL182361 | {4-[5-(4-Fluoro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN2O2/c1-21(2)12-22-16-9-5-13(6-10-16)17-11-18(23-20-17)14-3-7-15(19)8-4-14/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150558 (1-(3-{4-[3-(4-Chloro-phenyl)-isoxazol-5-yl]-phenox...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C23H26ClN3O2/c1-26-12-14-27(15-13-26)11-2-16-28-21-9-5-19(6-10-21)23-17-22(25-29-23)18-3-7-20(24)8-4-18/h3-10,17H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of interleukin-8 induced elastase release from human neutrophils				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150561 (1-(3-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-phenox...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H26FN3O2/c1-26-12-14-27(15-13-26)11-2-16-28-21-9-5-19(6-10-21)23-17-22(25-29-23)18-3-7-20(24)8-4-18/h3-10,17H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of interleukin-8 induced elastase release from human neutrophils				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50063753 (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50215968 (CHEMBL57324) Show SMILES Cc1cc(NC(=O)c2cc(I)cc(I)c2O)c(Cl)cc1C(C#N)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-20(28-22(30)16-7-14(25)8-19(26)21(16)29)18(24)9-15(11)17(10-27)12-2-4-13(23)5-3-12/h2-9,17,29H,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)				Bioorg Med Chem Lett 8: 1923-8 (1998) BindingDB Entry DOI: 10.7270/Q27S7QZM
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150569 ((3-{4-[3-(4-Chloro-phenyl)-isoxazol-5-yl]-phenoxy}...) Show SMILES CN(C)CCCOc1ccc(cc1)-c1cc(no1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN2O2/c1-23(2)12-3-13-24-18-10-6-16(7-11-18)20-14-19(22-25-20)15-4-8-17(21)9-5-15/h4-11,14H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150559 (CHEMBL182361 | {4-[5-(4-Fluoro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN2O2/c1-21(2)12-22-16-9-5-13(6-10-16)17-11-18(23-20-17)14-3-7-15(19)8-4-14/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of interleukin-8 induced elastase release from human neutrophils				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150574 (CHEMBL413959 | {2-[5-(4-Chloro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1ccccc1-c1cc(on1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2O2/c1-21(2)12-22-17-6-4-3-5-15(17)16-11-18(23-20-16)13-7-9-14(19)10-8-13/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150555 (1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2nc(no2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C22H25ClN4O2/c1-26-12-14-27(15-13-26)11-2-16-28-20-9-5-18(6-10-20)22-24-21(25-29-22)17-3-7-19(23)8-4-17/h3-10H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of interleukin-8 induced elastase release from human neutrophils				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50471718 (CHEMBL98026) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C22H14Cl4N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(25)9-20(11)28-22(30)16-7-14(24)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50215967 (CHEMBL56579) Show SMILES Cc1cc(NC(=O)c2cc(Cl)cc(Cl)c2O)c(Cl)cc1C(C#N)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H14Cl4N2O2/c1-11-6-20(28-22(30)16-7-14(24)8-19(26)21(16)29)18(25)9-15(11)17(10-27)12-2-4-13(23)5-3-12/h2-9,17,29H,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)				Bioorg Med Chem Lett 8: 1923-8 (1998) BindingDB Entry DOI: 10.7270/Q27S7QZM
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50045004 (9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...) Show SMILES CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O Show InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of DNA gyrase supercoiling in Escherichia coli.				Bioorg Med Chem Lett 8: 97-100 (1998) BindingDB Entry DOI: 10.7270/Q25141DT
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150567 (1-[4-(5-Phenyl-isoxazol-3-yl)-phenoxymethyl]-piper...) Show SMILES C(Oc1ccc(cc1)-c1cc(on1)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O2/c1-3-7-18(8-4-1)21-15-20(22-25-21)17-9-11-19(12-10-17)24-16-23-13-5-2-6-14-23/h1,3-4,7-12,15H,2,5-6,13-14,16H2	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150556 (1-Methyl-4-(3-{4-[3-(3-trifluoromethyl-phenyl)-iso...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C24H26F3N3O2/c1-29-11-13-30(14-12-29)10-3-15-31-21-8-6-18(7-9-21)23-17-22(28-32-23)19-4-2-5-20(16-19)24(25,26)27/h2,4-9,16-17H,3,10-15H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218645 (CHEMBL288462) Show SMILES CC(C)(C)c1cccc(-c2nc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H20N4O/c1-18(2,3)12-6-4-5-11(15(12)23)17-21-13-8-7-10(16(19)20)9-14(13)22-17/h4-9,23H,1-3H3,(H3,19,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150566 (1-Methyl-4-[4-(5-phenyl-isoxazol-3-yl)-phenoxymeth...) Show SMILES CN1CCN(COc2ccc(cc2)-c2cc(on2)-c2ccccc2)CC1 Show InChI InChI=1S/C21H23N3O2/c1-23-11-13-24(14-12-23)16-25-19-9-7-17(8-10-19)20-15-21(26-22-20)18-5-3-2-4-6-18/h2-10,15H,11-14,16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150568 (CHEMBL183819 | Dimethyl-{3-[4-(3-phenyl-isoxazol-5...) Show SMILES CN(C)CCCOc1ccc(cc1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C20H22N2O2/c1-22(2)13-6-14-23-18-11-9-17(10-12-18)20-15-19(21-24-20)16-7-4-3-5-8-16/h3-5,7-12,15H,6,13-14H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150570 (1-Methyl-4-[4-(5-phenyl-isoxazol-3-yl)-phenoxymeth...) Show SMILES CN1CCC(COc2ccc(cc2)-c2cc(on2)-c2ccccc2)CC1 Show InChI InChI=1S/C22H24N2O2/c1-24-13-11-17(12-14-24)16-25-20-9-7-18(8-10-20)21-15-22(26-23-21)19-5-3-2-4-6-19/h2-10,15,17H,11-14,16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50215357 (CHEMBL6353) Show SMILES ONC1c2cc(O)c(O)cc2-c2cc(O)c(O)cc12 Show InChI InChI=1S/C13H11NO5/c15-9-1-5-6-2-10(16)12(18)4-8(6)13(14-19)7(5)3-11(9)17/h1-4,13-19H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of DNA gyrase supercoiling in Escherichia coli.				Bioorg Med Chem Lett 8: 97-100 (1998) BindingDB Entry DOI: 10.7270/Q25141DT
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218644 (CHEMBL416972) Show SMILES NC(=N)c1ccc2cc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C21H17N3O/c22-21(23)16-7-6-15-12-19(24-20(15)13-16)14-8-10-18(11-9-14)25-17-4-2-1-3-5-17/h1-13,24H,(H3,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150560 (CHEMBL184583 | {3-[5-(4-Chloro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1cccc(c1)-c1cc(on1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2O2/c1-21(2)12-22-16-5-3-4-14(10-16)17-11-18(23-20-17)13-6-8-15(19)9-7-13/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150565 (1-(2-{4-[5-(4-Chloro-phenyl)-isoxazol-3-yl]-phenox...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cc(on2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C22H24ClN3O2/c1-25-10-12-26(13-11-25)14-15-27-20-8-4-17(5-9-20)21-16-22(28-24-21)18-2-6-19(23)7-3-18/h2-9,16H,10-15H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50471730 (CHEMBL101786) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(cc(c1O)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C24H14Cl2F6N2O2/c1-11-6-15(17(10-33)12-2-4-14(25)5-3-12)19(26)9-20(11)34-22(36)16-7-13(23(27,28)29)8-18(21(16)35)24(30,31)32/h2-9,17,35H,1H3,(H,34,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
Sporulation initiation phosphotransferase F/kinase A (Bacillus subtilis (strain 168))	BDBM50215963 (CHEMBL57687) Show SMILES Cc1cc(NC(=O)c2cc(I)c(O)c(I)c2)c(Cl)cc1C(C#N)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-20(28-22(30)13-7-18(25)21(29)19(26)8-13)17(24)9-15(11)16(10-27)12-2-4-14(23)5-3-12/h2-9,16,29H,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)				Bioorg Med Chem Lett 8: 1923-8 (1998) BindingDB Entry DOI: 10.7270/Q27S7QZM
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50471728 (CHEMBL100719) Show SMILES Oc1cccc(C(=O)Nc2ccc(Cl)c(Cl)c2)c1O Show InChI InChI=1S/C13H9Cl2NO3/c14-9-5-4-7(6-10(9)15)16-13(19)8-2-1-3-11(17)12(8)18/h1-6,17-18H,(H,16,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150571 (1-(3-{4-[3-(3-Chloro-phenyl)-isoxazol-5-yl]-phenox...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C23H26ClN3O2/c1-26-11-13-27(14-12-26)10-3-15-28-21-8-6-18(7-9-21)23-17-22(25-29-23)19-4-2-5-20(24)16-19/h2,4-9,16-17H,3,10-15H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218640 (CHEMBL38683) Show SMILES CC(C)(C)c1cc(-c2nc3cc(ccc3[nH]2)C2=NCCN2)c(O)c(c1)C(C)(C)C |t:18| Show InChI InChI=1S/C24H30N4O/c1-23(2,3)15-12-16(20(29)17(13-15)24(4,5)6)22-27-18-8-7-14(11-19(18)28-22)21-25-9-10-26-21/h7-8,11-13,29H,9-10H2,1-6H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218648 (CHEMBL290098) Show SMILES CC(C)(N)CNC(=O)c1ccc2[nH]c(nc2c1)-c1cc(cc(c1O)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C26H36N4O2/c1-24(2,3)16-12-17(21(31)18(13-16)25(4,5)6)22-29-19-10-9-15(11-20(19)30-22)23(32)28-14-26(7,8)27/h9-13,31H,14,27H2,1-8H3,(H,28,32)(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150557 (1-(3-{4-[3-(4-Fluoro-phenyl)-[1,2,4]oxadiazol-5-yl...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2nc(no2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H25FN4O2/c1-26-12-14-27(15-13-26)11-2-16-28-20-9-5-18(6-10-20)22-24-21(25-29-22)17-3-7-19(23)8-4-17/h3-10H,2,11-16H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150564 (CHEMBL425882 | Dimethyl-[4-(5-phenyl-isoxazol-3-yl...) Show SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccccc1 Show InChI InChI=1S/C18H18N2O2/c1-20(2)13-21-16-10-8-14(9-11-16)17-12-18(22-19-17)15-6-4-3-5-7-15/h3-12H,13H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150575 (1-Methyl-4-[4-(5-pyridin-2-yl-isoxazol-3-yl)-pheno...) Show SMILES CN1CCN(COc2ccc(cc2)-c2cc(on2)-c2ccccn2)CC1 Show InChI InChI=1S/C20H22N4O2/c1-23-10-12-24(13-11-23)15-25-17-7-5-16(6-8-17)19-14-20(26-22-19)18-4-2-3-9-21-18/h2-9,14H,10-13,15H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218643 (CHEMBL39634) Show SMILES CC(C)(C)c1cc(-c2nc3cc(ccc3[nH]2)C(N)=N)c(O)c(c1)C(C)(C)C Show InChI InChI=1S/C22H28N4O/c1-21(2,3)13-10-14(18(27)15(11-13)22(4,5)6)20-25-16-8-7-12(19(23)24)9-17(16)26-20/h7-11,27H,1-6H3,(H3,23,24)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150562 (CHEMBL184401 | Dimethyl-{4-[5-(4-nitro-phenyl)-iso...) Show SMILES CN(C)COc1ccc(cc1)-c1cc([o+][n-]1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H17N3O4/c1-20(2)12-24-16-9-5-13(6-10-16)17-11-18(25-19-17)14-3-7-15(8-4-14)21(22)23/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218655 (CHEMBL38914) Show SMILES CC(C)(C)c1cc(-c2nc3cc(ccc3o2)C(N)=N)c(O)c(c1)C(C)(C)C Show InChI InChI=1S/C22H27N3O2/c1-21(2,3)13-10-14(18(26)15(11-13)22(4,5)6)20-25-16-9-12(19(23)24)7-8-17(16)27-20/h7-11,26H,1-6H3,(H3,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218647 (CHEMBL38867) Show SMILES CC(C)(C)c1cc(-c2nc3ccc(cc3o2)C(N)=N)c(O)c(c1)C(C)(C)C Show InChI InChI=1S/C22H27N3O2/c1-21(2,3)13-10-14(18(26)15(11-13)22(4,5)6)20-25-16-8-7-12(19(23)24)9-17(16)27-20/h7-11,26H,1-6H3,(H3,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218659 (CHEMBL43691) Show SMILES NC(=N)c1ccc2[nH]c(nc2c1)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H21N5/c27-25(28)19-13-16-23-24(17-19)30-26(29-23)18-11-14-22(15-12-18)31(20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-17H,(H3,27,28)(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50471723 (CHEMBL98273) Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(ccc1O)C(F)(F)F Show InChI InChI=1S/C23H15Cl2F3N2O2/c1-12-8-16(18(11-29)13-2-5-15(24)6-3-13)19(25)10-20(12)30-22(32)17-9-14(23(26,27)28)4-7-21(17)31/h2-10,18,31H,1H3,(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50065970 (CHEMBL57656 | N-(3,4-Dichloro-phenyl)-2-hydroxy-3,...) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H7Cl2I2NO2/c14-9-2-1-7(5-10(9)15)18-13(20)8-3-6(16)4-11(17)12(8)19/h1-5,19H,(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...				J Med Chem 41: 2939-45 (1998) Article DOI: 10.1021/jm9803572 BindingDB Entry DOI: 10.7270/Q2VM4G0W
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50065970 (CHEMBL57656 | N-(3,4-Dichloro-phenyl)-2-hydroxy-3,...) Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H7Cl2I2NO2/c14-9-2-1-7(5-10(9)15)18-13(20)8-3-6(16)4-11(17)12(8)19/h1-5,19H,(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)				Bioorg Med Chem Lett 8: 1923-8 (1998) BindingDB Entry DOI: 10.7270/Q27S7QZM
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150576 (1-Methyl-4-(3-{4-[3-(4-phenoxy-phenyl)-isoxazol-5-...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2ccc(Oc3ccccc3)cc2)CC1 Show InChI InChI=1S/C29H31N3O3/c1-31-17-19-32(20-18-31)16-5-21-33-25-12-10-24(11-13-25)29-22-28(30-35-29)23-8-14-27(15-9-23)34-26-6-3-2-4-7-26/h2-4,6-15,22H,5,16-21H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150554 (4-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...) Show SMILES Clc1ccc(cc1)-c1noc(n1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C21H22ClN3O3/c22-18-6-2-16(3-7-18)20-23-21(28-24-20)17-4-8-19(9-5-17)27-13-1-10-25-11-14-26-15-12-25/h2-9H,1,10-15H2	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Sporulation kinase A (Bacillus subtilis (strain 168))	BDBM50218653 (CHEMBL39178) Show SMILES CC(C)(C)c1cc(cc(c1)C(C)(C)C)-c1nc2cc(ccc2[nH]1)C(N)=N Show InChI InChI=1S/C22H28N4/c1-21(2,3)15-9-14(10-16(12-15)22(4,5)6)20-25-17-8-7-13(19(23)24)11-18(17)26-20/h7-12H,1-6H3,(H3,23,24)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.				Bioorg Med Chem Lett 11: 1545-8 (2001) BindingDB Entry DOI: 10.7270/Q2V69MSM
					More data for this Ligand-Target Pair

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