Compile Data Set for Download or QSAR

Found 61 hits with Last Name = 'fuwa' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189039 (4-(4-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulf...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(cc1OCCCN1CCCC1)C(=O)c1ccc(COC(=O)NCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1 Show InChI InChI=1S/C51H61ClF2N6O8S2/c1-34(60(44-31-39(53)19-23-42(44)54)70(65,66)40-20-17-38(52)18-21-40)41-22-16-37(30-45(41)67-29-9-28-59-26-7-8-27-59)49(62)36-14-12-35(13-15-36)32-68-51(64)56-25-6-2-5-24-55-47(61)11-4-3-10-46-48-43(33-69-46)57-50(63)58-48/h12-23,30-31,34,43,46,48H,2-11,24-29,32-33H2,1H3,(H,55,61)(H,56,64)(H2,57,58,63)/t34?,43-,46-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189028 (4-(4-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulf...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(cc1OCCCN1CCCC1)C(=O)c1ccc(COC(=O)NCCCCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1 Show InChI InChI=1S/C54H67ClF2N6O8S2/c1-37(63(47-34-42(56)22-26-45(47)57)73(68,69)43-23-20-41(55)21-24-43)44-25-19-40(33-48(44)70-32-12-31-62-29-10-11-30-62)52(65)39-17-15-38(16-18-39)35-71-54(67)59-28-9-5-3-2-4-8-27-58-50(64)14-7-6-13-49-51-46(36-72-49)60-53(66)61-51/h15-26,33-34,37,46,49,51H,2-14,27-32,35-36H2,1H3,(H,58,64)(H,59,67)(H2,60,61,66)/t37?,46-,49-,51-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189041 (CHEMBL269580 | N-(5-(2-(4-(N-(1-(4-benzoyl-2-(3-(p...) Show SMILES CC(N(c1cc(F)c(OCC(=O)NCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(cc1OCCCN1CCCC1)C(=O)c1ccccc1 Show InChI InChI=1S/C51H61ClF2N6O8S2/c1-34(39-22-17-36(50(63)35-13-4-2-5-14-35)29-44(39)67-28-12-27-59-25-10-11-26-59)60(70(65,66)38-20-18-37(52)19-21-38)43-30-41(54)45(31-40(43)53)68-32-48(62)56-24-9-3-8-23-55-47(61)16-7-6-15-46-49-42(33-69-46)57-51(64)58-49/h2,4-5,13-14,17-22,29-31,34,42,46,49H,3,6-12,15-16,23-28,32-33H2,1H3,(H,55,61)(H,56,62)(H2,57,58,64)/t34?,42-,46-,49-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189036 (4-chloro-N-phenyl-N-(1-(2-(3-(pyrrolidin-1-yl)prop...) Show SMILES CC(N(c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H31ClN2O3S/c1-22(26-12-5-6-13-27(26)33-21-9-20-29-18-7-8-19-29)30(24-10-3-2-4-11-24)34(31,32)25-16-14-23(28)15-17-25/h2-6,10-17,22H,7-9,18-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189031 (CHEMBL266043 | N-(8-(2-(4-(N-(1-(4-benzoyl-2-(3-(p...) Show SMILES CC(N(c1cc(F)c(OCC(=O)NCCCCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(cc1OCCCN1CCCC1)C(=O)c1ccccc1 Show InChI InChI=1S/C54H67ClF2N6O8S2/c1-37(42-25-20-39(53(66)38-16-7-6-8-17-38)32-47(42)70-31-15-30-62-28-13-14-29-62)63(73(68,69)41-23-21-40(55)22-24-41)46-33-44(57)48(34-43(46)56)71-35-51(65)59-27-12-5-3-2-4-11-26-58-50(64)19-10-9-18-49-52-45(36-72-49)60-54(67)61-52/h6-8,16-17,20-25,32-34,37,45,49,52H,2-5,9-15,18-19,26-31,35-36H2,1H3,(H,58,64)(H,59,65)(H2,60,61,67)/t37?,45-,49-,52-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189045 (CHEMBL373983 | N-(1-(4-benzoyl-2-(3-(pyrrolidin-1-...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(cc1OCCCN1CCCC1)C(=O)c1ccccc1 Show InChI InChI=1S/C34H33ClF2N2O4S/c1-24(39(32-23-28(36)13-17-31(32)37)44(41,42)29-14-11-27(35)12-15-29)30-16-10-26(34(40)25-8-3-2-4-9-25)22-33(30)43-21-7-20-38-18-5-6-19-38/h2-4,8-17,22-24H,5-7,18-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189043 (4-fluoro-N-phenyl-N-(1-(2-(3-(pyrrolidin-1-yl)prop...) Show SMILES CC(N(c1ccccc1)S(=O)(=O)c1ccc(F)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H31FN2O3S/c1-22(26-12-5-6-13-27(26)33-21-9-20-29-18-7-8-19-29)30(24-10-3-2-4-11-24)34(31,32)25-16-14-23(28)15-17-25/h2-6,10-17,22H,7-9,18-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189048 (CHEMBL385166 | N-phenyl-N-(1-(2-(3-(pyrrolidin-1-y...) Show SMILES CC(N(c1ccccc1)S(=O)(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C28H31F3N2O3S/c1-22(26-12-5-6-13-27(26)36-21-9-20-32-18-7-8-19-32)33(24-10-3-2-4-11-24)37(34,35)25-16-14-23(15-17-25)28(29,30)31/h2-6,10-17,22H,7-9,18-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189029 (4-chloro-N-(2-methoxyphenyl)-N-(1-(2-(3-(pyrrolidi...) Show SMILES COc1ccccc1N(C(C)c1ccccc1OCCCN1CCCC1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H33ClN2O4S/c1-22(25-10-3-5-12-27(25)35-21-9-20-30-18-7-8-19-30)31(26-11-4-6-13-28(26)34-2)36(32,33)24-16-14-23(29)15-17-24/h3-6,10-17,22H,7-9,18-21H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189044 (4-chloro-N-(2-chlorophenyl)-N-(1-(2-(3-(pyrrolidin...) Show SMILES CC(N(c1ccccc1Cl)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H30Cl2N2O3S/c1-21(24-9-2-5-12-27(24)34-20-8-19-30-17-6-7-18-30)31(26-11-4-3-10-25(26)29)35(32,33)23-15-13-22(28)14-16-23/h2-5,9-16,21H,6-8,17-20H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186512 (CHEMBL377810 | benzyl 6-benzyl-2-hydroxy-5-oxo-5,6...) Show SMILES OC1C=CC(=O)C(Cc2ccccc2)N1C(=O)OCc1ccccc1 |c:2| Show InChI InChI=1S/C20H19NO4/c22-18-11-12-19(23)21(17(18)13-15-7-3-1-4-8-15)20(24)25-14-16-9-5-2-6-10-16/h1-12,17,19,23H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189046 (4-chloro-N-(3-methoxyphenyl)-N-(1-(2-(3-(pyrrolidi...) Show SMILES COc1cccc(c1)N(C(C)c1ccccc1OCCCN1CCCC1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H33ClN2O4S/c1-22(27-11-3-4-12-28(27)35-20-8-19-30-17-5-6-18-30)31(24-9-7-10-25(21-24)34-2)36(32,33)26-15-13-23(29)14-16-26/h3-4,7,9-16,21-22H,5-6,8,17-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189037 (4-chloro-N-(3-chlorophenyl)-N-(1-(2-(3-(pyrrolidin...) Show SMILES CC(N(c1cccc(Cl)c1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H30Cl2N2O3S/c1-21(26-10-2-3-11-27(26)34-19-7-18-30-16-4-5-17-30)31(24-9-6-8-23(29)20-24)35(32,33)25-14-12-22(28)13-15-25/h2-3,6,8-15,20-21H,4-5,7,16-19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189026 (CHEMBL211428 | N-phenyl-N-(1-(2-(3-(pyrrolidin-1-y...) Show SMILES CC(N(c1ccccc1)S(=O)(=O)c1ccccc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H32N2O3S/c1-23(26-17-8-9-18-27(26)32-22-12-21-28-19-10-11-20-28)29(24-13-4-2-5-14-24)33(30,31)25-15-6-3-7-16-25/h2-9,13-18,23H,10-12,19-22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186512 (CHEMBL377810 | benzyl 6-benzyl-2-hydroxy-5-oxo-5,6...) Show SMILES OC1C=CC(=O)C(Cc2ccccc2)N1C(=O)OCc1ccccc1 |c:2| Show InChI InChI=1S/C20H19NO4/c22-18-11-12-19(23)21(17(18)13-15-7-3-1-4-8-15)20(24)25-14-16-9-5-2-6-10-16/h1-12,17,19,23H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186500 (1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one | ...) Show SMILES O=C(N1CC=CC(=O)C1Cc1ccccc1)c1ccccc1 |c:4| Show InChI InChI=1S/C19H17NO2/c21-18-12-7-13-20(19(22)16-10-5-2-6-11-16)17(18)14-15-8-3-1-4-9-15/h1-12,17H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189032 (4-chloro-N-(1-(2-(3-(diethylamino)propoxy)phenyl)e...) Show SMILES CCN(CC)CCCOc1ccccc1C(C)N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H31ClF2N2O3S/c1-4-31(5-2)17-8-18-35-27-10-7-6-9-24(27)20(3)32(26-19-22(29)13-16-25(26)30)36(33,34)23-14-11-21(28)12-15-23/h6-7,9-16,19-20H,4-5,8,17-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189047 (4-chloro-N-(4-methoxyphenyl)-N-(1-(2-(3-(pyrrolidi...) Show SMILES COc1ccc(cc1)N(C(C)c1ccccc1OCCCN1CCCC1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H33ClN2O4S/c1-22(27-8-3-4-9-28(27)35-21-7-20-30-18-5-6-19-30)31(24-12-14-25(34-2)15-13-24)36(32,33)26-16-10-23(29)11-17-26/h3-4,8-17,22H,5-7,18-21H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186507 ((5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone | CHEMB...) Show SMILES O=C1C=CC[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 |c:2| Show InChI InChI=1S/C20H20O3/c21-18-12-7-13-19(22-14-16-8-3-1-4-9-16)20(18)23-15-17-10-5-2-6-11-17/h1-12,19-20H,13-15H2/t19-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189034 (CHEMBL211955 | N-(2-benzoylphenyl)-4-chloro-N-(1-(...) Show SMILES CC(N(c1ccccc1C(=O)c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C34H35ClN2O4S/c1-26(30-14-6-8-17-33(30)41-25-11-24-36-22-9-10-23-36)37(42(39,40)29-20-18-28(35)19-21-29)32-16-7-5-15-31(32)34(38)27-12-3-2-4-13-27/h2-8,12-21,26H,9-11,22-25H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189040 (4-chloro-N-(4-chlorophenyl)-N-(1-(2-(3-(pyrrolidin...) Show SMILES CC(N(c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H30Cl2N2O3S/c1-21(26-7-2-3-8-27(26)34-20-6-19-30-17-4-5-18-30)31(24-13-9-22(28)10-14-24)35(32,33)25-15-11-23(29)12-16-25/h2-3,7-16,21H,4-6,17-20H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186507 ((5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone | CHEMB...) Show SMILES O=C1C=CC[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 |c:2| Show InChI InChI=1S/C20H20O3/c21-18-12-7-13-19(22-14-16-8-3-1-4-9-16)20(18)23-15-17-10-5-2-6-11-17/h1-12,19-20H,13-15H2/t19-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189027 (4-bromo-N-phenyl-N-(1-(2-(3-(pyrrolidin-1-yl)propo...) Show SMILES CC(N(c1ccccc1)S(=O)(=O)c1ccc(Br)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H31BrN2O3S/c1-22(26-12-5-6-13-27(26)33-21-9-20-29-18-7-8-19-29)30(24-10-3-2-4-11-24)34(31,32)25-16-14-23(28)15-17-25/h2-6,10-17,22H,7-9,18-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189035 (4-chloro-N-(2,5-difluorophenyl)-N-(1-(2-(3-(pyrrol...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H29ClF2N2O3S/c1-20(24-7-2-3-8-27(24)35-18-6-17-31-15-4-5-16-31)32(26-19-22(29)11-14-25(26)30)36(33,34)23-12-9-21(28)10-13-23/h2-3,7-14,19-20H,4-6,15-18H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189030 (4-chloro-N-(2,5-difluorophenyl)-N-(1-(2-(3-(piperi...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCCC1 Show InChI InChI=1S/C28H31ClF2N2O3S/c1-21(25-8-3-4-9-28(25)36-19-7-18-32-16-5-2-6-17-32)33(27-20-23(30)12-15-26(27)31)37(34,35)24-13-10-22(29)11-14-24/h3-4,8-15,20-21H,2,5-7,16-19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186500 (1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one | ...) Show SMILES O=C(N1CC=CC(=O)C1Cc1ccccc1)c1ccccc1 |c:4| Show InChI InChI=1S/C19H17NO2/c21-18-12-7-13-20(19(22)16-10-5-2-6-11-16)17(18)14-15-8-3-1-4-9-15/h1-12,17H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189038 (CHEMBL378664 | N-(3-benzoylphenyl)-4-chloro-N-(1-(...) Show SMILES CC(N(c1cccc(c1)C(=O)c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C34H35ClN2O4S/c1-26(32-15-5-6-16-33(32)41-24-10-23-36-21-7-8-22-36)37(42(39,40)31-19-17-29(35)18-20-31)30-14-9-13-28(25-30)34(38)27-11-3-2-4-12-27/h2-6,9,11-20,25-26H,7-8,10,21-24H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189049 (CHEMBL212926 | N-(4-benzoylphenyl)-4-chloro-N-(1-(...) Show SMILES CC(N(c1ccc(cc1)C(=O)c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C34H35ClN2O4S/c1-26(32-12-5-6-13-33(32)41-25-9-24-36-22-7-8-23-36)37(42(39,40)31-20-16-29(35)17-21-31)30-18-14-28(15-19-30)34(38)27-10-3-2-4-11-27/h2-6,10-21,26H,7-9,22-25H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189033 (4-chloro-N-(2,5-difluorophenyl)-N-(1-(2-(3-morphol...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCOCC1 Show InChI InChI=1S/C27H29ClF2N2O4S/c1-20(24-5-2-3-6-27(24)36-16-4-13-31-14-17-35-18-15-31)32(26-19-22(29)9-12-25(26)30)37(33,34)23-10-7-21(28)8-11-23/h2-3,5-12,19-20H,4,13-18H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186513 (CHEMBL212569 | benzyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES O=C(OCc1ccccc1)N1CC=CC(=O)C1Cc1ccccc1 |c:13| Show InChI InChI=1S/C20H19NO3/c22-19-12-7-13-21(18(19)14-16-8-3-1-4-9-16)20(23)24-15-17-10-5-2-6-11-17/h1-12,18H,13-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186510 ((2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone | CHE...) Show SMILES CO[C@@H]1CCCC(=O)[C@H]1OCc1ccccc1 Show InChI InChI=1S/C14H18O3/c1-16-13-9-5-8-12(15)14(13)17-10-11-6-3-2-4-7-11/h2-4,6-7,13-14H,5,8-10H2,1H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186504 (2-benzyl-1-(phenylsulfonyl)-1,2-dihydropyridin-3(6...) Show SMILES O=C1C=CCN(C1Cc1ccccc1)S(=O)(=O)c1ccccc1 |c:2| Show InChI InChI=1S/C18H17NO3S/c20-18-12-7-13-19(17(18)14-15-8-3-1-4-9-15)23(21,22)16-10-5-2-6-11-16/h1-12,17H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186506 ((5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone | ...) Show SMILES CO[C@@H]1CC=CC(=O)[C@H]1OCc1ccccc1 |c:4| Show InChI InChI=1S/C14H16O3/c1-16-13-9-5-8-12(15)14(13)17-10-11-6-3-2-4-7-11/h2-8,13-14H,9-10H2,1H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186502 (CHEMBL210178 | methyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES COC(=O)N1CC=CC(=O)C1Cc1ccccc1 |c:6| Show InChI InChI=1S/C14H15NO3/c1-18-14(17)15-9-5-8-13(16)12(15)10-11-6-3-2-4-7-11/h2-8,12H,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186513 (CHEMBL212569 | benzyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES O=C(OCc1ccccc1)N1CC=CC(=O)C1Cc1ccccc1 |c:13| Show InChI InChI=1S/C20H19NO3/c22-19-12-7-13-21(18(19)14-16-8-3-1-4-9-16)20(23)24-15-17-10-5-2-6-11-17/h1-12,18H,13-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186502 (CHEMBL210178 | methyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES COC(=O)N1CC=CC(=O)C1Cc1ccccc1 |c:6| Show InChI InChI=1S/C14H15NO3/c1-18-14(17)15-9-5-8-13(16)12(15)10-11-6-3-2-4-7-11/h2-8,12H,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186506 ((5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone | ...) Show SMILES CO[C@@H]1CC=CC(=O)[C@H]1OCc1ccccc1 |c:4| Show InChI InChI=1S/C14H16O3/c1-16-13-9-5-8-12(15)14(13)17-10-11-6-3-2-4-7-11/h2-8,13-14H,9-10H2,1H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186504 (2-benzyl-1-(phenylsulfonyl)-1,2-dihydropyridin-3(6...) Show SMILES O=C1C=CCN(C1Cc1ccccc1)S(=O)(=O)c1ccccc1 |c:2| Show InChI InChI=1S/C18H17NO3S/c20-18-12-7-13-19(17(18)14-15-8-3-1-4-9-15)23(21,22)16-10-5-2-6-11-16/h1-12,17H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186510 ((2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone | CHE...) Show SMILES CO[C@@H]1CCCC(=O)[C@H]1OCc1ccccc1 Show InChI InChI=1S/C14H18O3/c1-16-13-9-5-8-12(15)14(13)17-10-11-6-3-2-4-7-11/h2-4,6-7,13-14H,5,8-10H2,1H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50189042 (CHEMBL214301 | N-(1-(4-benzoyl-2-(3-(pyrrolidin-1-...) Show SMILES CC(N(c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(cc1OCCCN1CCCC1)C(=O)c1ccccc1 Show InChI InChI=1S/C34H35ClN2O4S/c1-26(37(30-13-6-3-7-14-30)42(39,40)31-18-16-29(35)17-19-31)32-20-15-28(34(38)27-11-4-2-5-12-27)25-33(32)41-24-10-23-36-21-8-9-22-36/h2-7,11-20,25-26H,8-10,21-24H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186508 ((5R,6S)-5-(benzyloxy)-6-methoxycyclohex-2-enone | ...) Show SMILES CO[C@H]1[C@@H](CC=CC1=O)OCc1ccccc1 |c:5| Show InChI InChI=1S/C14H16O3/c1-16-14-12(15)8-5-9-13(14)17-10-11-6-3-2-4-7-11/h2-8,13-14H,9-10H2,1H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186508 ((5R,6S)-5-(benzyloxy)-6-methoxycyclohex-2-enone | ...) Show SMILES CO[C@H]1[C@@H](CC=CC1=O)OCc1ccccc1 |c:5| Show InChI InChI=1S/C14H16O3/c1-16-14-12(15)8-5-9-13(14)17-10-11-6-3-2-4-7-11/h2-8,13-14H,9-10H2,1H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186505 (CHEMBL211287 | methyl 2-benzyl-3-oxopiperidine-1-c...) Show SMILES COC(=O)N1CCCC(=O)C1Cc1ccccc1 Show InChI InChI=1S/C14H17NO3/c1-18-14(17)15-9-5-8-13(16)12(15)10-11-6-3-2-4-7-11/h2-4,6-7,12H,5,8-10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186501 ((2S,3R)-2-(benzyloxy)-5-hydroxy-3-methoxycyclohexa...) Show SMILES CO[C@@H]1CC(O)CC(=O)[C@H]1OCc1ccccc1 Show InChI InChI=1S/C14H18O4/c1-17-13-8-11(15)7-12(16)14(13)18-9-10-5-3-2-4-6-10/h2-6,11,13-15H,7-9H2,1H3/t11?,13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186501 ((2S,3R)-2-(benzyloxy)-5-hydroxy-3-methoxycyclohexa...) Show SMILES CO[C@@H]1CC(O)CC(=O)[C@H]1OCc1ccccc1 Show InChI InChI=1S/C14H18O4/c1-17-13-8-11(15)7-12(16)14(13)18-9-10-5-3-2-4-6-10/h2-6,11,13-15H,7-9H2,1H3/t11?,13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186499 (CHEMBL377425 | benzyl 2-benzyl-3-hydroxypiperidine...) Show SMILES OC1CCCN(C1Cc1ccccc1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C20H23NO3/c22-19-12-7-13-21(18(19)14-16-8-3-1-4-9-16)20(23)24-15-17-10-5-2-6-11-17/h1-6,8-11,18-19,22H,7,12-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186503 ((2S,3R)-2,3-bis(benzyloxy)cyclohexanone | CHEMBL20...) Show SMILES O=C1CCC[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 Show InChI InChI=1S/C20H22O3/c21-18-12-7-13-19(22-14-16-8-3-1-4-9-16)20(18)23-15-17-10-5-2-6-11-17/h1-6,8-11,19-20H,7,12-15H2/t19-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186503 ((2S,3R)-2,3-bis(benzyloxy)cyclohexanone | CHEMBL20...) Show SMILES O=C1CCC[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 Show InChI InChI=1S/C20H22O3/c21-18-12-7-13-19(22-14-16-8-3-1-4-9-16)20(18)23-15-17-10-5-2-6-11-17/h1-6,8-11,19-20H,7,12-15H2/t19-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186499 (CHEMBL377425 | benzyl 2-benzyl-3-hydroxypiperidine...) Show SMILES OC1CCCN(C1Cc1ccccc1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C20H23NO3/c22-19-12-7-13-21(18(19)14-16-8-3-1-4-9-16)20(23)24-15-17-10-5-2-6-11-17/h1-6,8-11,18-19,22H,7,12-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186509 ((2S,3R)-3-(benzyloxy)-5-hydroxy-2-methoxycyclohexa...) Show SMILES CO[C@H]1[C@@H](CC(O)CC1=O)OCc1ccccc1 Show InChI InChI=1S/C14H18O4/c1-17-14-12(16)7-11(15)8-13(14)18-9-10-5-3-2-4-6-10/h2-6,11,13-15H,7-9H2,1H3/t11?,13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 61 total )  |  Next  |  Last  >>

Jump to: