Compile Data Set for Download or QSAR

Found 28 hits with Last Name = 'gorsuch' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247911 (2-(4-Pyridyl)-isothiazol-3(2H)-one | CHEMBL499919) Show SMILES O=c1ccsn1-c1ccncc1 Show InChI InChI=1S/C8H6N2OS/c11-8-3-6-12-10(8)7-1-4-9-5-2-7/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50247911 (2-(4-Pyridyl)-isothiazol-3(2H)-one | CHEMBL499919) Show SMILES O=c1ccsn1-c1ccncc1 Show InChI InChI=1S/C8H6N2OS/c11-8-3-6-12-10(8)7-1-4-9-5-2-7/h1-6H	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247615 (2-(3,4,5-trifluorophenyl)isothiazol-3(2H)-one | CH...) Show SMILES Fc1cc(cc(F)c1F)-n1sccc1=O Show InChI InChI=1S/C9H4F3NOS/c10-6-3-5(4-7(11)9(6)12)13-8(14)1-2-15-13/h1-4H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50292429 (2-Hydroxy-6-pentadecyl-benzoic acid | 2-Pentadecyl...) Show SMILES OC(=O)c1c(O)cccc1CCCCCCC\C=C/C\C=C/CC=C Show InChI InChI=1S/C22H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h2,4-5,7-8,15,17-18,23H,1,3,6,9-14,16H2,(H,24,25)/b5-4-,8-7-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged HAT p300 expressed in Sf21-Baculovirus system				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247616 (2-(3-chloro-2-fluorophenyl)isothiazol-3(2H)-one | ...) Show SMILES Fc1c(Cl)cccc1-n1sccc1=O Show InChI InChI=1S/C9H5ClFNOS/c10-6-2-1-3-7(9(6)11)12-8(13)4-5-14-12/h1-5H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247912 (2-(4-Dimethylaminoaniline)-isothiazol-3(2H)-one | ...) Show SMILES CN(C)c1ccc(cc1)-n1sccc1=O Show InChI InChI=1S/C11H12N2OS/c1-12(2)9-3-5-10(6-4-9)13-11(14)7-8-15-13/h3-8H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50241990 (CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@@H](-[#6][C@@]12[#6]-[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6](=O)-[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)-[#6]1=O)[#6]2=O)-[#6](-[#6])=[#6] |r,TLB:40:39:26.24.37:15.8.9| Show InChI InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,31,39-40H,7,13,15,18,20-21H2,1-6,8-10H3/t27-,28+,31?,37+,38-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of HAT PCAF				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50241990 (CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@@H](-[#6][C@@]12[#6]-[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6](=O)-[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)-[#6]1=O)[#6]2=O)-[#6](-[#6])=[#6] |r,TLB:40:39:26.24.37:15.8.9| Show InChI InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,31,39-40H,7,13,15,18,20-21H2,1-6,8-10H3/t27-,28+,31?,37+,38-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of HAT p300				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50037078 (2-(Phenyl)-isothiazolo[5,4-b]pyridin-3(2H)-one | 2...) Show SMILES O=c1n(sc2ncccc12)-c1ccccc1 Show InChI InChI=1S/C12H8N2OS/c15-12-10-7-4-8-13-11(10)16-14(12)9-5-2-1-3-6-9/h1-8H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247913 (2-(3-Pyridyl)-isothiazol-3(2H)-one | CHEMBL487498) Show SMILES O=c1ccsn1-c1cccnc1 Show InChI InChI=1S/C8H6N2OS/c11-8-3-5-12-10(8)7-2-1-4-9-6-7/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247909 (2-(4-Morpholinoaniline)-isothiazol-3(2H)-one | CHE...) Show SMILES O=c1ccsn1-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C13H14N2O2S/c16-13-5-10-18-15(13)12-3-1-11(2-4-12)14-6-8-17-9-7-14/h1-5,10H,6-9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50247909 (2-(4-Morpholinoaniline)-isothiazol-3(2H)-one | CHE...) Show SMILES O=c1ccsn1-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C13H14N2O2S/c16-13-5-10-18-15(13)12-3-1-11(2-4-12)14-6-8-17-9-7-14/h1-5,10H,6-9H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50247913 (2-(3-Pyridyl)-isothiazol-3(2H)-one | CHEMBL487498) Show SMILES O=c1ccsn1-c1cccnc1 Show InChI InChI=1S/C8H6N2OS/c11-8-3-5-12-10(8)7-2-1-4-9-6-7/h1-6H	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247584 (2-(2-Pyridyl)-isothiazol-3(2H)-one | CHEMBL489494) Show SMILES O=c1ccsn1-c1ccccn1 Show InChI InChI=1S/C8H6N2OS/c11-8-4-6-12-10(8)7-3-1-2-5-9-7/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247600 (5-chloro-4-methyl-2-phenylisothiazol-3(2H)-one | C...) Show SMILES Cc1c(Cl)sn(-c2ccccc2)c1=O Show InChI InChI=1S/C10H8ClNOS/c1-7-9(11)14-12(10(7)13)8-5-3-2-4-6-8/h2-6H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50240683 (2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...) Show SMILES O=c1ccsn1-c1ccccc1 Show InChI InChI=1S/C9H7NOS/c11-9-6-7-12-10(9)8-4-2-1-3-5-8/h1-7H	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50240683 (2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...) Show SMILES O=c1ccsn1-c1ccccc1 Show InChI InChI=1S/C9H7NOS/c11-9-6-7-12-10(9)8-4-2-1-3-5-8/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50247584 (2-(2-Pyridyl)-isothiazol-3(2H)-one | CHEMBL489494) Show SMILES O=c1ccsn1-c1ccccn1 Show InChI InChI=1S/C8H6N2OS/c11-8-4-6-12-10(8)7-3-1-2-5-9-7/h1-6H	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247588 (4-methyl-2-phenylisothiazol-3(2H)-one | CHEMBL4742...) Show SMILES Cc1csn(-c2ccccc2)c1=O Show InChI InChI=1S/C10H9NOS/c1-8-7-13-11(10(8)12)9-5-3-2-4-6-9/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247590 (4-Azidomethyl-2-phenyl-isothiazol-3(2H)-one | CHEM...) Show SMILES [N-]=[N+]=NCc1csn(-c2ccccc2)c1=O Show InChI InChI=1S/C10H8N4OS/c11-13-12-6-8-7-16-14(10(8)15)9-4-2-1-3-5-9/h1-5,7H,6H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247585 (5-Azidomethyl-2-phenylisothiazol-3(2H)-one | CHEMB...) Show SMILES [N-]=[N+]=NCc1cc(=O)n(s1)-c1ccccc1 Show InChI InChI=1S/C10H8N4OS/c11-13-12-7-9-6-10(15)14(16-9)8-4-2-1-3-5-8/h1-6H,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247589 (4-Methoxymethyl-2-phenyl-isothiazol-3(2H)-one | CH...) Show SMILES COCc1csn(-c2ccccc2)c1=O Show InChI InChI=1S/C11H11NO2S/c1-14-7-9-8-15-12(11(9)13)10-5-3-2-4-6-10/h2-6,8H,7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247910 (5-Hydroxymethyl-2-phenylisothiazol-3(2H)-one | CHE...) Show SMILES OCc1cc(=O)n(s1)-c1ccccc1 Show InChI InChI=1S/C10H9NO2S/c12-7-9-6-10(13)11(14-9)8-4-2-1-3-5-8/h1-6,12H,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247914 (5-Acetoxymethyl-2-phenylisothiazol-3(2H)-one | CHE...) Show SMILES CC(=O)OCc1cc(=O)n(s1)-c1ccccc1 Show InChI InChI=1S/C12H11NO3S/c1-9(14)16-8-11-7-12(15)13(17-11)10-5-3-2-4-6-10/h2-7H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247587 (2,5-diphenylisothiazol-3(2H)-one | CHEMBL500224 | ...) Show SMILES O=c1cc(sn1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C15H11NOS/c17-15-11-14(12-7-3-1-4-8-12)18-16(15)13-9-5-2-6-10-13/h1-11H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247586 (5-Methyl-2-N-Phenylisothiazol-3(2H)-one | CHEMBL48...) Show SMILES Cc1cc(=O)n(s1)-c1ccccc1 Show InChI InChI=1S/C10H9NOS/c1-8-7-10(12)11(13-8)9-5-3-2-4-6-9/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247583 (5-Phenylureidomethyl-2-phenylisothiazol-3(2H)-one ...) Show SMILES O=C(Nc1ccccc1)OCc1cc(=O)n(s1)-c1ccccc1 Show InChI InChI=1S/C17H14N2O3S/c20-16-11-15(23-19(16)14-9-5-2-6-10-14)12-22-17(21)18-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247614 (4-Methyl-5-methoxy-2-phenyl-isothiazol-3(2H)-one |...) Show SMILES COc1sn(-c2ccccc2)c(=O)c1C Show InChI InChI=1S/C11H11NO2S/c1-8-10(13)12(15-11(8)14-2)9-6-4-3-5-7-9/h3-7H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assay				Bioorg Med Chem 17: 467-74 (2009) Article DOI: 10.1016/j.bmc.2008.11.079 BindingDB Entry DOI: 10.7270/Q2H70GRB
					More data for this Ligand-Target Pair