Found 65 hits with Last Name = 'greaney' and Initial = 'mf' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319324
(1-(3,4-dimethoxyphenyl)-2-(1-m-tolyl-1H-tetrazol-5...)Show InChI InChI=1S/C19H19N3O3S/c1-13-5-4-6-15(9-13)22-19(11-20-21-22)26-12-16(23)14-7-8-17(24-2)18(10-14)25-3/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319333
(3-(1-(3-chlorophenyl)-1H-tetrazol-5-yl)-1-phenylpr...)Show InChI InChI=1S/C17H14ClN3O/c18-14-7-4-8-15(11-14)21-16(12-19-20-21)9-10-17(22)13-5-2-1-3-6-13/h1-8,11-12H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319316
(1-(3,4-dimethoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-...)Show InChI InChI=1S/C18H17N3O3S/c1-23-16-9-8-13(10-17(16)24-2)15(22)12-25-18-11-19-20-21(18)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319331
(2-(1-cyclohexyl-1H-tetrazol-5-ylthio)-1-(3,4-dimet...)Show InChI InChI=1S/C18H23N3O3S/c1-23-16-9-8-13(10-17(16)24-2)15(22)12-25-18-11-19-20-21(18)14-6-4-3-5-7-14/h8-11,14H,3-7,12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319360
(1-(3-methoxyphenyl)-3-(1-phenyl-1H-tetrazol-5-yl)p...)Show InChI InChI=1S/C18H17N3O2/c1-23-17-9-5-6-14(12-17)18(22)11-10-16-13-19-20-21(16)15-7-3-2-4-8-15/h2-9,12-13H,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319310
(3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylthio)buta...)Show InChI InChI=1S/C14H17N3OS/c1-14(2,3)12(18)10-19-13-9-15-16-17(13)11-7-5-4-6-8-11/h4-9H,10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 252 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319311
(1-phenyl-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone...)Show InChI InChI=1S/C16H13N3OS/c20-15(13-7-3-1-4-8-13)12-21-16-11-17-18-19(16)14-9-5-2-6-10-14/h1-11H,12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319317
(1-phenyl-3-(1-phenyl-1H-tetrazol-5-ylthio)propan-2...)Show InChI InChI=1S/C17H15N3OS/c21-16(11-14-7-3-1-4-8-14)13-22-17-12-18-19-20(17)15-9-5-2-6-10-15/h1-10,12H,11,13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319343
(3-(1-(3-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylp...)Show InChI InChI=1S/C18H17N3O2/c1-23-17-9-5-8-15(12-17)21-16(13-19-20-21)10-11-18(22)14-6-3-2-4-7-14/h2-9,12-13H,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 304 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319358
(1-(3-chlorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)pr...)Show InChI InChI=1S/C17H14ClN3O/c18-14-6-4-5-13(11-14)17(22)10-9-16-12-19-20-21(16)15-7-2-1-3-8-15/h1-8,11-12H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319341
(1-phenyl-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one...)Show InChI InChI=1S/C17H15N3O/c21-17(14-7-3-1-4-8-14)12-11-16-13-18-19-20(16)15-9-5-2-6-10-15/h1-10,13H,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319344
(3-(1-(4-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylp...)Show InChI InChI=1S/C18H17N3O2/c1-23-17-10-7-15(8-11-17)21-16(13-19-20-21)9-12-18(22)14-5-3-2-4-6-14/h2-8,10-11,13H,9,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 426 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319318
(1-(furan-2-yl)-2-(1-phenyl-1H-tetrazol-5-ylthio)et...)Show InChI InChI=1S/C14H11N3O2S/c18-12(13-7-4-8-19-13)10-20-14-9-15-16-17(14)11-5-2-1-3-6-11/h1-9H,10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 485 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319365
(3-(5-(4-methoxyphenyl)-1H-tetrazol-1-yl)-1-phenylp...)Show InChI InChI=1S/C17H16N4O2/c1-23-15-9-7-14(8-10-15)17-18-19-20-21(17)12-11-16(22)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 493 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319362
(1-cyclohexyl-3-(1-phenyl-1H-tetrazol-5-yl)propan-1...)Show InChI InChI=1S/C16H20N4O/c21-15(13-7-3-1-4-8-13)11-12-16-17-18-19-20(16)14-9-5-2-6-10-14/h2,5-6,9-10,13H,1,3-4,7-8,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 506 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319359
(1-(4-dichlorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)...)Show InChI InChI=1S/C17H14ClN3O/c18-14-8-6-13(7-9-14)17(22)11-10-16-12-19-20-21(16)15-4-2-1-3-5-15/h1-9,12H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 539 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319332
(3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)-1-phenylpr...)Show InChI InChI=1S/C17H14ClN3O/c18-14-6-8-15(9-7-14)21-16(12-19-20-21)10-11-17(22)13-4-2-1-3-5-13/h1-9,12H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 575 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319334
(1-phenyl-3-(1-p-tolyl-1H-tetrazol-5-yl)propan-1-on...)Show InChI InChI=1S/C18H17N3O/c1-14-7-9-16(10-8-14)21-17(13-19-20-21)11-12-18(22)15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 588 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319356
(1-(3-fluorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)pr...)Show InChI InChI=1S/C17H14FN3O/c18-14-6-4-5-13(11-14)17(22)10-9-16-12-19-20-21(16)15-7-2-1-3-8-15/h1-8,11-12H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 597 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319336
(1-phenyl-3-(1-o-tolyl-1H-tetrazol-5-yl)propan-1-on...)Show InChI InChI=1S/C17H16N4O/c1-13-7-5-6-10-15(13)21-17(18-19-20-21)12-11-16(22)14-8-3-2-4-9-14/h2-10H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 683 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319345
(4-(5-(3-oxo-3-phenylpropyl)-1H-tetrazol-1-yl)benzo...)Show InChI InChI=1S/C18H14N4O/c19-12-14-6-8-16(9-7-14)22-17(13-20-21-22)10-11-18(23)15-4-2-1-3-5-15/h1-9,13H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 686 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319366
(3-(5-(benzo[d][1,3]dioxol-5-yl)-1H-tetrazol-1-yl)-...)Show InChI InChI=1S/C17H14N4O3/c22-14(12-4-2-1-3-5-12)8-9-21-17(18-19-20-21)13-6-7-15-16(10-13)24-11-23-15/h1-7,10H,8-9,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 722 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319364
(3-(5-(2-methoxyphenyl)-1H-tetrazol-1-yl)-1-phenylp...)Show InChI InChI=1S/C17H16N4O2/c1-23-16-10-6-5-9-14(16)17-18-19-20-21(17)12-11-15(22)13-7-3-2-4-8-13/h2-10H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 751 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319354
(1-phenyl-4-(1-phenyl-1H-tetrazol-5-yl)butan-2-one ...)Show InChI InChI=1S/C17H16N4O/c22-16(13-14-7-3-1-4-8-14)11-12-17-18-19-20-21(17)15-9-5-2-6-10-15/h1-10H,11-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319363
(1-phenyl-3-(5-phenyl-1H-tetrazol-1-yl)propan-1-one...)Show InChI InChI=1S/C16H14N4O/c21-15(13-7-3-1-4-8-13)11-12-20-16(17-18-19-20)14-9-5-2-6-10-14/h1-10H,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 843 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319329
(2-(1-benzyl-1H-tetrazol-5-ylthio)-1-(3,4-dimethoxy...)Show InChI InChI=1S/C19H19N3O3S/c1-24-17-9-8-15(10-18(17)25-2)16(23)13-26-19-11-20-21-22(19)12-14-6-4-3-5-7-14/h3-11H,12-13H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319351
(3-(1-cyclohexyl-1H-tetrazol-5-yl)-1-phenylpropan-1...)Show InChI InChI=1S/C17H21N3O/c21-17(14-7-3-1-4-8-14)12-11-16-13-18-19-20(16)15-9-5-2-6-10-15/h1,3-4,7-8,13,15H,2,5-6,9-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 915 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319339
(3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylsulfonyl)...)Show InChI InChI=1S/C14H17N3O3S/c1-14(2,3)12(18)10-21(19,20)13-9-15-16-17(13)11-7-5-4-6-8-11/h4-9H,10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 943 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319335
(1-phenyl-3-(1-m-tolyl-1H-tetrazol-5-yl)propan-1-on...)Show InChI InChI=1S/C18H17N3O/c1-14-6-5-9-16(12-14)21-17(13-19-20-21)10-11-18(22)15-7-3-2-4-8-15/h2-9,12-13H,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 948 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319321
(1-(3,4-dimethoxyphenyl)-2-(1-isopropyl-1H-tetrazol...)Show InChI InChI=1S/C15H19N3O3S/c1-10(2)18-15(8-16-17-18)22-9-12(19)11-5-6-13(20-3)14(7-11)21-4/h5-8,10H,9H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 954 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319340
(1-phenyl-2-(1-phenyl-1H-tetrazol-5-yloxy)ethanone ...)Show InChI InChI=1S/C16H13N3O2/c20-15(13-7-3-1-4-8-13)12-21-16-11-17-18-19(16)14-9-5-2-6-10-14/h1-11H,12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 971 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319350
(3-(1-cyclopentyl-1H-tetrazol-5-yl)-1-phenylpropan-...)Show InChI InChI=1S/C16H19N3O/c20-16(13-6-2-1-3-7-13)11-10-15-12-17-18-19(15)14-8-4-5-9-14/h1-3,6-7,12,14H,4-5,8-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 987 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319355
(1-phenyl-5-(1-phenyl-1H-tetrazol-5-yl)pentan-3-one...)Show InChI InChI=1S/C18H18N4O/c23-17(12-11-15-7-3-1-4-8-15)13-14-18-19-20-21-22(18)16-9-5-2-6-10-16/h1-10H,11-14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 987 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319326
(1-(3,4-dimethoxyphenyl)-2-(1-(2,4-dimethylphenyl)-...)Show InChI InChI=1S/C20H21N3O3S/c1-13-5-7-16(14(2)9-13)23-20(11-21-22-23)27-12-17(24)15-6-8-18(25-3)19(10-15)26-4/h5-11H,12H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319328
(2-(1-(4-chlorophenyl)-1H-tetrazol-5-ylthio)-1-(3,4...)Show InChI InChI=1S/C18H16ClN3O3S/c1-24-16-8-3-12(9-17(16)25-2)15(23)11-26-18-10-20-21-22(18)14-6-4-13(19)5-7-14/h3-10H,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319314
(1-(4-methoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylth...)Show InChI InChI=1S/C17H15N3O2S/c1-22-15-9-7-13(8-10-15)16(21)12-23-17-11-18-19-20(17)14-5-3-2-4-6-14/h2-11H,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319348
(1-phenyl-3-(1-(1,2,3,4-tetrahydronaphthalen-1-yl)-...)Show InChI InChI=1S/C21H21N3O/c25-21(17-8-2-1-3-9-17)14-13-18-15-22-23-24(18)20-12-6-10-16-7-4-5-11-19(16)20/h1-5,7-9,11,15,20H,6,10,12-14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319368
(3-(5-(3-chlorophenyl)-1H-tetrazol-1-yl)-1-phenylpr...)Show InChI InChI=1S/C16H13ClN4O/c17-14-8-4-7-13(11-14)16-18-19-20-21(16)10-9-15(22)12-5-2-1-3-6-12/h1-8,11H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319373
(1-phenyl-3-(5-(thiophen-3-yl)-1H-tetrazol-1-yl)pro...)Show InChI InChI=1S/C15H13N3OS/c19-15(12-4-2-1-3-5-12)7-6-13-10-16-17-18(13)14-8-9-20-11-14/h1-5,8-11H,6-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319338
(3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylsulfinyl)...)Show InChI InChI=1S/C14H17N3O2S/c1-14(2,3)12(18)10-20(19)13-9-15-16-17(13)11-7-5-4-6-8-11/h4-9H,10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319312
(1-(4-fluorophenyl)-2-(1-phenyl-1H-tetrazol-5-ylthi...)Show InChI InChI=1S/C16H12FN3OS/c17-13-8-6-12(7-9-13)15(21)11-22-16-10-18-19-20(16)14-4-2-1-3-5-14/h1-10H,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319313
(1-(3-fluorophenyl)-2-(1-phenyl-1H-tetrazol-5-ylthi...)Show InChI InChI=1S/C16H12FN3OS/c17-13-6-4-5-12(9-13)15(21)11-22-16-10-18-19-20(16)14-7-2-1-3-8-14/h1-10H,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319323
(1-(3,4-dimethoxyphenyl)-2-(1-o-tolyl-1H-tetrazol-5...)Show InChI InChI=1S/C19H19N3O3S/c1-13-6-4-5-7-15(13)22-19(11-20-21-22)26-12-16(23)14-8-9-17(24-2)18(10-14)25-3/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319352
(3-[1-(1-adamantyl)-1H-tetrazol-5-yl]-1-phenylpropa...)Show SMILES O=C(CCc1cnnn1[C@@]12CC3CC(CC(C3)C1)C2)c1ccccc1 |r,TLB:8:9:12:16.14.15,THB:14:13:10:16.15.17,14:15:12.13.18:10,17:9:12:16.14.15,17:15:12:9.18.10| Show InChI InChI=1S/C21H25N3O/c25-20(18-4-2-1-3-5-18)7-6-19-14-22-23-24(19)21-11-15-8-16(12-21)10-17(9-15)13-21/h1-5,14-17H,6-13H2/t15?,16?,17?,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319347
(3-(1-(2,3-dihydro-1H-inden-1-yl)-1H-tetrazol-5-yl)...)Show InChI InChI=1S/C19H18N4O/c24-18(15-7-2-1-3-8-15)12-13-19-20-21-22-23(19)17-11-10-14-6-4-5-9-16(14)17/h1-9,17H,10-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319315
(1-(3-methoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylth...)Show InChI InChI=1S/C17H15N3O2S/c1-22-15-9-5-6-13(10-15)16(21)12-23-17-11-18-19-20(17)14-7-3-2-4-8-14/h2-11H,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319327
(1-(3,4-dimethoxyphenyl)-2-(1-(2-methoxyphenyl)-1H-...)Show InChI InChI=1S/C19H19N3O4S/c1-24-16-7-5-4-6-14(16)22-19(11-20-21-22)27-12-15(23)13-8-9-17(25-2)18(10-13)26-3/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319322
(2-(1-tert-butyl-1H-tetrazol-5-ylthio)-1-(3,4-dimet...)Show InChI InChI=1S/C16H21N3O3S/c1-16(2,3)19-15(9-17-18-19)23-10-12(20)11-6-7-13(21-4)14(8-11)22-5/h6-9H,10H2,1-5H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319319
(2-(1-phenyl-1H-tetrazol-5-ylthio)-1-(thiophen-2-yl...)Show InChI InChI=1S/C14H11N3OS2/c18-12(13-7-4-8-19-13)10-20-14-9-15-16-17(14)11-5-2-1-3-6-11/h1-9H,10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319330
(1-(3,4-dimethoxyphenyl)-2-(1-(thiophen-2-ylmethyl)...)Show InChI InChI=1S/C17H17N3O3S2/c1-22-15-6-5-12(8-16(15)23-2)14(21)11-25-17-9-18-19-20(17)10-13-4-3-7-24-13/h3-9H,10-11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |