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Compile Data Set for Download or QSAR

Found 104 hits with Last Name = 'grzywa' and Initial = 'r'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Myeloblastin


(Homo sapiens (Human))
BDBM50263166
PNG
(CHEMBL4071346)
Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](CC(O)=O)C(=O)NC(CCC)P(=O)(Oc3ccc(Cl)cc3)Oc3ccc(Cl)cc3)[C@@]1([H])NC(=O)N2 |r|
Show InChI InChI=1S/C44H55Cl2N6O11PS/c1-4-7-37(64(61,62-30-18-12-27(45)13-19-30)63-31-20-14-28(46)15-21-31)51-42(58)33(23-38(55)56)47-41(57)32(22-26-10-16-29(53)17-11-26)48-43(59)39(25(2)3)50-36(54)9-6-5-8-35-40-34(24-65-35)49-44(60)52-40/h10-21,25,32-35,37,39-40,53H,4-9,22-24H2,1-3H3,(H,47,57)(H,48,59)(H,50,54)(H,51,58)(H,55,56)(H2,49,52,60)/t32-,33-,34-,35-,37?,39-,40-/m0/s1
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5.40n/an/an/an/an/an/an/an/a



INSERM UMR1100,"Centre d'Etude des Pathologies Respiratoires" , Université de Tours , 37032 Tours , France.

Curated by ChEMBL


Assay Description
Inhibition of human PR3 using ABZ-VADnVADYQ-EDDnp as substrate by FRET assay


J Med Chem 61: 1858-1870 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01416
BindingDB Entry DOI: 10.7270/Q25B04ZT
More data for this
Ligand-Target Pair
Myeloblastin


(Homo sapiens (Human))
BDBM50263172
PNG
(CHEMBL4085013)
Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](CC(O)=O)C(=O)NC(C)P(=O)(Oc3ccc(Cl)cc3)Oc3ccc(Cl)cc3)[C@@]1([H])NC(=O)N2 |r|
Show InChI InChI=1S/C42H49Cl2N6O11PS/c1-24(62(59,60-29-16-10-26(43)11-17-29)61-30-18-12-27(44)13-19-30)45-39(55)32(22-37(53)54)46-40(56)31(21-25-8-14-28(51)15-9-25)47-41(57)34-5-4-20-50(34)36(52)7-3-2-6-35-38-33(23-63-35)48-42(58)49-38/h8-19,24,31-35,38,51H,2-7,20-23H2,1H3,(H,45,55)(H,46,56)(H,47,57)(H,53,54)(H2,48,49,58)/t24?,31-,32-,33-,34-,35-,38-/m0/s1
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21n/an/an/an/an/an/an/an/a



INSERM UMR1100,"Centre d'Etude des Pathologies Respiratoires" , Université de Tours , 37032 Tours , France.

Curated by ChEMBL


Assay Description
Inhibition of human PR3 using ABZ-VADnVADYQ-EDDnp as substrate by FRET assay


J Med Chem 61: 1858-1870 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01416
BindingDB Entry DOI: 10.7270/Q25B04ZT
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244147
PNG
((4-methoxybenzyl)carbamothioyl(1-aminopentyl)phosp...)
Show SMILES CCCCC(N)=P(O)(O)C(=S)NCc1ccc(OC)cc1
Show InChI InChI=1S/C14H23N2O3PS/c1-3-4-5-13(15)20(17,18)14(21)16-10-11-6-8-12(19-2)9-7-11/h6-9,17-18H,3-5,10,15H2,1-2H3,(H,16,21)
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143n/an/an/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Cytosol aminopeptidase


(Homo sapiens (Human))
BDBM50129679
PNG
((1-Amino-3-methyl-butyl)-phosphonic acid | 1-amino...)
Show SMILES CC(C)CC(N)P(O)(O)=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)
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230n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of leucine aminopeptidase


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Cytosol aminopeptidase


(Homo sapiens (Human))
BDBM50316047
PNG
(1-amino-2-methylbutylphosphonic acid monophenylest...)
Show SMILES CC(C)CC(N)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C11H18NO3P/c1-9(2)8-11(12)16(13,14)15-10-6-4-3-5-7-10/h3-7,9,11H,8,12H2,1-2H3,(H,13,14)
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230n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of leucine aminopeptidase


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Cytosol aminopeptidase


(Homo sapiens (Human))
BDBM50024592
PNG
((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Show SMILES [NH3+][C@H](Cc1ccccc1)P(O)([O-])=O
Show InChI InChI=1S/C8H12NO3P/c9-8(13(10,11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,9H2,(H2,10,11,12)/t8-/m0/s1
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420n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of leucine aminopeptidase


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Cytosol aminopeptidase


(Homo sapiens (Human))
BDBM50316048
PNG
(1-amino-2-phenylethylphosphonic acid monophenyl es...)
Show SMILES NC(Cc1ccccc1)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C14H16NO3P/c15-14(11-12-7-3-1-4-8-12)19(16,17)18-13-9-5-2-6-10-13/h1-10,14H,11,15H2,(H,16,17)
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420n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of leucine aminopeptidase


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Myeloblastin


(Homo sapiens (Human))
BDBM50263165
PNG
(CHEMBL4102959)
Show SMILES CC(NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(C)=O)P(=O)(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C34H37Cl2N4O10P/c1-20(51(48,49-26-13-7-23(35)8-14-26)50-27-15-9-24(36)10-16-27)37-32(45)29(19-31(43)44)38-33(46)28(18-22-5-11-25(42)12-6-22)39-34(47)30-4-3-17-40(30)21(2)41/h5-16,20,28-30,42H,3-4,17-19H2,1-2H3,(H,37,45)(H,38,46)(H,39,47)(H,43,44)/t20?,28-,29-,30-/m0/s1
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3.60E+3n/an/an/an/an/an/an/an/a



INSERM UMR1100,"Centre d'Etude des Pathologies Respiratoires" , Université de Tours , 37032 Tours , France.

Curated by ChEMBL


Assay Description
Inhibition of human PR3 using ABZ-VADnVADYQ-EDDnp as substrate by FRET assay


J Med Chem 61: 1858-1870 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01416
BindingDB Entry DOI: 10.7270/Q25B04ZT
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50024592
PNG
((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Show SMILES [NH3+][C@H](Cc1ccccc1)P(O)([O-])=O
Show InChI InChI=1S/C8H12NO3P/c9-8(13(10,11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,9H2,(H2,10,11,12)/t8-/m0/s1
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2.75E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase N


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50316048
PNG
(1-amino-2-phenylethylphosphonic acid monophenyl es...)
Show SMILES NC(Cc1ccccc1)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C14H16NO3P/c15-14(11-12-7-3-1-4-8-12)19(16,17)18-13-9-5-2-6-10-13/h1-10,14H,11,15H2,(H,16,17)
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2.75E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase N


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50316047
PNG
(1-amino-2-methylbutylphosphonic acid monophenylest...)
Show SMILES CC(C)CC(N)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C11H18NO3P/c1-9(2)8-11(12)16(13,14)15-10-6-4-3-5-7-10/h3-7,9,11H,8,12H2,1-2H3,(H,13,14)
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5.30E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase N


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50129679
PNG
((1-Amino-3-methyl-butyl)-phosphonic acid | 1-amino...)
Show SMILES CC(C)CC(N)P(O)(O)=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)
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5.30E+4n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase N


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204146
PNG
(1-amino-2-phenylethyl(1-hydroxy-3-phenylpropyl)pho...)
Show SMILES NC(Cc1ccccc1)P(O)(O)C(=O)CCc1ccccc1
Show InChI InChI=1S/C17H22NO3P/c18-16(13-15-9-5-2-6-10-15)22(20,21)17(19)12-11-14-7-3-1-4-8-14/h1-10,16,20-22H,11-13,18H2
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n/an/a 240n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244150
PNG
((4-methoxybenzyl)carbamothioyl(1-amino-3-phenylpro...)
Show SMILES COc1ccc(CNC(=S)P(O)(O)=C(N)CCc2ccccc2)cc1
Show InChI InChI=1S/C18H23N2O3PS/c1-23-16-10-7-15(8-11-16)13-20-18(25)24(21,22)17(19)12-9-14-5-3-2-4-6-14/h2-8,10-11,21-22H,9,12-13,19H2,1H3,(H,20,25)
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n/an/a 380n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244148
PNG
(1-amino-3-methylbutyl(hexylcarbamothioyl)phosphini...)
Show SMILES CCCCCCNC(=S)P(O)(O)=C(N)CC(C)C
Show InChI InChI=1S/C12H27N2O2PS/c1-4-5-6-7-8-14-12(18)17(15,16)11(13)9-10(2)3/h10,15-16H,4-9,13H2,1-3H3,(H,14,18)
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n/an/a 500n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316042
PNG
(1-amino-3-phenylpropylphosphonic acid mono-(4-isop...)
Show SMILES CC(C)c1ccc(OP(O)(=O)C(N)CCc2ccccc2)cc1
Show InChI InChI=1S/C18H24NO3P/c1-14(2)16-9-11-17(12-10-16)22-23(20,21)18(19)13-8-15-6-4-3-5-7-15/h3-7,9-12,14,18H,8,13,19H2,1-2H3,(H,20,21)
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n/an/a 500n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204160
PNG
(1-amino-2-methylpropyl(1-hydroxy-3-phenylpropyl)ph...)
Show SMILES CC(C)C(N)P(O)(O)C(=O)CCc1ccccc1
Show InChI InChI=1S/C13H22NO3P/c1-10(2)13(14)18(16,17)12(15)9-8-11-6-4-3-5-7-11/h3-7,10,13,16-18H,8-9,14H2,1-2H3
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n/an/a 500n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204163
PNG
(CHEMBL227345 | alpha1-(1-amino-3-methylbutane)-alp...)
Show SMILES CC(C)CC(N)=P(O)(O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C13H21N2O3P/c1-10(2)8-12(14)19(17,18)13(16)15-9-11-6-4-3-5-7-11/h3-7,10,17-18H,8-9,14H2,1-2H3,(H,15,16)
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n/an/a 530n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204159
PNG
(CHEMBL226863 | alpha1-(1-amino-1-phenylmethane)-al...)
Show SMILES NC(Cc1ccccc1)P(O)(O)C(=O)Cc1ccccc1
Show InChI InChI=1S/C16H20NO3P/c17-15(11-13-7-3-1-4-8-13)21(19,20)16(18)12-14-9-5-2-6-10-14/h1-10,15,19-21H,11-12,17H2
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n/an/a 550n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204161
PNG
(CHEMBL227290 | bis-alpha-(1-amino-1-phenylmethane)...)
Show SMILES NC(Cc1ccccc1)P(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C16H21N2O2P/c17-15(11-13-7-3-1-4-8-13)21(19,20)16(18)12-14-9-5-2-6-10-14/h1-10,15,18-21H,11-12,17H2
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n/an/a 600n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244108
PNG
((4-methoxybenzyl)carbamothioyl(1-aminobutyl)phosph...)
Show SMILES CCCC(N)=P(O)(O)C(=S)NCc1ccc(OC)cc1
Show InChI InChI=1S/C13H21N2O3PS/c1-3-4-12(14)19(16,17)13(20)15-9-10-5-7-11(18-2)8-6-10/h5-8,16-17H,3-4,9,14H2,1-2H3,(H,15,20)
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n/an/a 680n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204157
PNG
(CHEMBL227340 | alpha1-(1-amino-1-phenylmethane)-al...)
Show SMILES NC(Cc1ccccc1)P(O)(O)C(=N)CCc1ccccc1
Show InChI InChI=1S/C17H23N2O2P/c18-16(12-11-14-7-3-1-4-8-14)22(20,21)17(19)13-15-9-5-2-6-10-15/h1-10,17-18,20-22H,11-13,19H2
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n/an/a 710n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244146
PNG
(1-aminopentyl(phenethylcarbamothioyl)phosphinic ac...)
Show SMILES CCCCC(N)=P(O)(O)C(=S)NCCc1ccccc1
Show InChI InChI=1S/C14H23N2O2PS/c1-2-3-9-13(15)19(17,18)14(20)16-11-10-12-7-5-4-6-8-12/h4-8,17-18H,2-3,9-11,15H2,1H3,(H,16,20)
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n/an/a 730n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204149
PNG
(CHEMBL390323 | bis-alpha-(1-amino-3-phenylpropane)...)
Show SMILES NC(CCc1ccccc1)P(O)(O)C(=N)CCc1ccccc1
Show InChI InChI=1S/C18H25N2O2P/c19-17(13-11-15-7-3-1-4-8-15)23(21,22)18(20)14-12-16-9-5-2-6-10-16/h1-10,17,20-23H,11-14,19H2
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n/an/a 830n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204148
PNG
(CHEMBL227347 | alpha1-(1-amino-2-methylpropane)-al...)
Show SMILES CC(C)C(N)=P(O)(O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C12H19N2O3P/c1-9(2)11(13)18(16,17)12(15)14-8-10-6-4-3-5-7-10/h3-7,9,16-17H,8,13H2,1-2H3,(H,14,15)
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n/an/a 930n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316033
PNG
(1-aminopentylphosphonic acid mono-(4-methylphenyl)...)
Show SMILES CCCCC(N)P(O)(=O)Oc1ccc(C)cc1
Show InChI InChI=1S/C12H20NO3P/c1-3-4-5-12(13)17(14,15)16-11-8-6-10(2)7-9-11/h6-9,12H,3-5,13H2,1-2H3,(H,14,15)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204150
PNG
(1-amino-3-methylbutyl(1-hydroxy-3-phenylpropyl)pho...)
Show SMILES CC(C)CC(N)P(O)(O)C(=O)CCc1ccccc1
Show InChI InChI=1S/C14H24NO3P/c1-11(2)10-13(15)19(17,18)14(16)9-8-12-6-4-3-5-7-12/h3-7,11,13,17-19H,8-10,15H2,1-2H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316028
PNG
(1-aminopropylphosphonic acid mono-(4-tbutylphenyl)...)
Show SMILES CCC(N)P(O)(=O)Oc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C13H22NO3P/c1-5-12(14)18(15,16)17-11-8-6-10(7-9-11)13(2,3)4/h6-9,12H,5,14H2,1-4H3,(H,15,16)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244106
PNG
((4-methoxybenzyl)carbamothioyl(1-aminoethyl)phosph...)
Show SMILES COc1ccc(CNC(=S)P(O)(O)=C(C)N)cc1
Show InChI InChI=1S/C11H17N2O3PS/c1-8(12)17(14,15)11(18)13-7-9-3-5-10(16-2)6-4-9/h3-6,14-15H,7,12H2,1-2H3,(H,13,18)
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n/an/a 1.12E+3n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244110
PNG
(1-amino-2-methylpropyl(hexylcarbamothioyl)phosphin...)
Show SMILES CCCCCCNC(=S)P(O)(O)=C(N)C(C)C
Show InChI InChI=1S/C11H25N2O2PS/c1-4-5-6-7-8-13-11(17)16(14,15)10(12)9(2)3/h9,14-15H,4-8,12H2,1-3H3,(H,13,17)
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n/an/a 1.18E+3n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316034
PNG
(1-aminopentylphosphonic acid mono-(3,4-dimethylphe...)
Show SMILES CCCCC(N)P(O)(=O)Oc1ccc(C)c(C)c1
Show InChI InChI=1S/C13H22NO3P/c1-4-5-6-13(14)18(15,16)17-12-8-7-10(2)11(3)9-12/h7-9,13H,4-6,14H2,1-3H3,(H,15,16)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244109
PNG
(1-amino-2-methylpropyl(isobutylcarbamothioyl)phosp...)
Show SMILES CC(C)CNC(=S)P(O)(O)=C(N)C(C)C
Show InChI InChI=1S/C9H21N2O2PS/c1-6(2)5-11-9(15)14(12,13)8(10)7(3)4/h6-7,12-13H,5,10H2,1-4H3,(H,11,15)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316043
PNG
(1-amino-3-phenylpropylphosphonic acid mono-(4-t-bu...)
Show SMILES CC(C)(C)c1ccc(OP(O)(=O)C(N)CCc2ccccc2)cc1
Show InChI InChI=1S/C19H26NO3P/c1-19(2,3)16-10-12-17(13-11-16)23-24(21,22)18(20)14-9-15-7-5-4-6-8-15/h4-8,10-13,18H,9,14,20H2,1-3H3,(H,21,22)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316039
PNG
(1-amino-3-phenylpropylphosphonic acid mono-(3,4-di...)
Show SMILES Cc1ccc(OP(O)(=O)C(N)CCc2ccccc2)cc1C
Show InChI InChI=1S/C17H22NO3P/c1-13-8-10-16(12-14(13)2)21-22(19,20)17(18)11-9-15-6-4-3-5-7-15/h3-8,10,12,17H,9,11,18H2,1-2H3,(H,19,20)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244107
PNG
(1-aminobutyl(phenethylcarbamothioyl)phosphinic aci...)
Show SMILES CCCC(N)=P(O)(O)C(=S)NCCc1ccccc1
Show InChI InChI=1S/C13H21N2O2PS/c1-2-6-12(14)18(16,17)13(19)15-10-9-11-7-4-3-5-8-11/h3-5,7-8,16-17H,2,6,9-10,14H2,1H3,(H,15,19)
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n/an/a 2.28E+3n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316044
PNG
(1-amino-3-phenylpropylphosphonic acid mono-(4-meth...)
Show SMILES COc1ccc(OP(O)(=O)C(N)CCc2ccccc2)cc1
Show InChI InChI=1S/C16H20NO4P/c1-20-14-8-10-15(11-9-14)21-22(18,19)16(17)12-7-13-5-3-2-4-6-13/h2-6,8-11,16H,7,12,17H2,1H3,(H,18,19)
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n/an/a 2.90E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316060
PNG
(1-aminopropylphosphonic acid mono-(3,4-dimethylphe...)
Show SMILES CCC(N)P(O)(=O)Oc1ccc(C)c(C)c1
Show InChI InChI=1S/C11H18NO3P/c1-4-11(12)16(13,14)15-10-6-5-8(2)9(3)7-10/h5-7,11H,4,12H2,1-3H3,(H,13,14)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204168
PNG
(1-amino-3-methylbutyl(1-hydroxypentyl)phosphinic a...)
Show SMILES CCCCC(=O)P(O)(O)C(N)CC(C)C
Show InChI InChI=1S/C10H24NO3P/c1-4-5-6-10(12)15(13,14)9(11)7-8(2)3/h8-9,13-15H,4-7,11H2,1-3H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50204147
PNG
(1-amino-2-phenylethyl(1-amino-3-methylbutyl)phosph...)
Show SMILES CC(C)CC(N)P(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C13H23N2O2P/c1-10(2)8-12(14)18(16,17)13(15)9-11-6-4-3-5-7-11/h3-7,10,12,15-18H,8-9,14H2,1-2H3
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n/an/a 4.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of APN


Bioorg Med Chem Lett 17: 1516-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.028
BindingDB Entry DOI: 10.7270/Q2C24W3B
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50244105
PNG
(1-aminoethyl(phenethylcarbamothioyl)phosphinic aci...)
Show SMILES CC(N)=P(O)(O)C(=S)NCCc1ccccc1
Show InChI InChI=1S/C11H17N2O2PS/c1-9(12)16(14,15)11(17)13-8-7-10-5-3-2-4-6-10/h2-6,14-15H,7-8,12H2,1H3,(H,13,17)
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n/an/a 4.20E+3n/an/an/an/an/an/a



Wroc£?aw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N


Bioorg Med Chem Lett 18: 3734-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.050
BindingDB Entry DOI: 10.7270/Q2H41R6T
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316053
PNG
(1-aminohexylphosphonic acid monophenyl ester | CHE...)
Show SMILES CCCCCC(N)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C12H20NO3P/c1-2-3-5-10-12(13)17(14,15)16-11-8-6-4-7-9-11/h4,6-9,12H,2-3,5,10,13H2,1H3,(H,14,15)
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n/an/a 4.80E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316040
PNG
(1-amino-3-phenylpropylphosphonic acid mono-(2,3,5-...)
Show SMILES Cc1cc(C)c(C)c(OP(O)(=O)C(N)CCc2ccccc2)c1
Show InChI InChI=1S/C18H24NO3P/c1-13-11-14(2)15(3)17(12-13)22-23(20,21)18(19)10-9-16-7-5-4-6-8-16/h4-8,11-12,18H,9-10,19H2,1-3H3,(H,20,21)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316052
PNG
(1-aminopentylphosphonic acid monophenyl ester | CH...)
Show SMILES CCCCC(N)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C11H18NO3P/c1-2-3-9-11(12)16(13,14)15-10-7-5-4-6-8-10/h4-8,11H,2-3,9,12H2,1H3,(H,13,14)
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n/an/a 5.60E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316055
PNG
(1-amino-3-phenylpropylphosphonic acid monophenyles...)
Show SMILES NC(CCc1ccccc1)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C15H18NO3P/c16-15(12-11-13-7-3-1-4-8-13)20(17,18)19-14-9-5-2-6-10-14/h1-10,15H,11-12,16H2,(H,17,18)
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n/an/a 6.20E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316046
PNG
(1-amino-3-phenylpropylphosphonic acid mono-(4-(1,1...)
Show SMILES CC(C)(C)CC(C)(C)c1ccc(OP(O)(=O)C(N)CCc2ccccc2)cc1
Show InChI InChI=1S/C23H34NO3P/c1-22(2,3)17-23(4,5)19-12-14-20(15-13-19)27-28(25,26)21(24)16-11-18-9-7-6-8-10-18/h6-10,12-15,21H,11,16-17,24H2,1-5H3,(H,25,26)
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n/an/a 6.30E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316059
PNG
(1-aminopropylphosphonic acid mono-(4-methylphenyl)...)
Show SMILES CCC(N)P(O)(=O)Oc1ccc(C)cc1
Show InChI InChI=1S/C10H16NO3P/c1-3-10(11)15(12,13)14-9-6-4-8(2)5-7-9/h4-7,10H,3,11H2,1-2H3,(H,12,13)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316057
PNG
(1-aminoethylphosphonic acid mono-(4-t-butylphenyl)...)
Show SMILES CC(N)P(O)(=O)Oc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C12H20NO3P/c1-9(13)17(14,15)16-11-7-5-10(6-8-11)12(2,3)4/h5-9H,13H2,1-4H3,(H,14,15)
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n/an/a 8.20E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50316048
PNG
(1-amino-2-phenylethylphosphonic acid monophenyl es...)
Show SMILES NC(Cc1ccccc1)P(O)(=O)Oc1ccccc1
Show InChI InChI=1S/C14H16NO3P/c15-14(11-12-7-3-1-4-8-12)19(16,17)18-13-9-5-2-6-10-13/h1-10,14H,11,15H2,(H,16,17)
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n/an/a 8.20E+3n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
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