Compile Data Set for Download or QSAR

Found 61 hits with Last Name = 'gu' and Initial = 'jd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058204 ((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](NC(=O)c1cccc2cc(NC[C@@H](N)CS)ccc12)C(O)=O Show InChI InChI=1S/C19H25N3O3S2/c1-27-8-7-17(19(24)25)22-18(23)16-4-2-3-12-9-14(5-6-15(12)16)21-10-13(20)11-26/h2-6,9,13,17,21,26H,7-8,10-11,20H2,1H3,(H,22,23)(H,24,25)/t13-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058199 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](NC(=S)c1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C19H25N3O2S3/c1-27-9-8-17(19(23)24)22-18(26)15-6-2-5-14-13(15)4-3-7-16(14)21-10-12(20)11-25/h2-7,12,17,21,25H,8-11,20H2,1H3,(H,22,26)(H,23,24)/t12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50058202 ((S)-2-[(2-{(S)-2-[((R)-2-Amino-3-mercapto-propiony...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](N)CS)C(O)=O Show InChI InChI=1S/C24H36N4O5S2/c1-14(2)20(27(3)22(30)17(25)13-34)23(31)28-12-16-8-6-5-7-15(16)11-19(28)21(29)26-18(24(32)33)9-10-35-4/h5-8,14,17-20,34H,9-13,25H2,1-4H3,(H,26,29)(H,32,33)/t17-,18-,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Human farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284949 ((S)-2-{[(S)-2-((S)-2-{[(S)-2-((R)-2,6-Diamino-hexa...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)C(O)=O Show InChI InChI=1S/C29H46N6O6S2/c1-17(2)23(34(3)28(39)26(42)33-24(36)20(31)11-7-8-13-30)27(38)35-16-19-10-6-5-9-18(19)15-22(35)25(37)32-21(29(40)41)12-14-43-4/h5-6,9-10,17,20-23,26,42H,7-8,11-16,30-31H2,1-4H3,(H,32,37)(H,33,36)(H,40,41)/t20-,21+,22+,23+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058202 ((S)-2-[(2-{(S)-2-[((R)-2-Amino-3-mercapto-propiony...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](N)CS)C(O)=O Show InChI InChI=1S/C24H36N4O5S2/c1-14(2)20(27(3)22(30)17(25)13-34)23(31)28-12-16-8-6-5-7-15(16)11-19(28)21(29)26-18(24(32)33)9-10-35-4/h5-8,14,17-20,34H,9-13,25H2,1-4H3,(H,26,29)(H,32,33)/t17-,18-,19-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058208 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](NC(=O)c1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C19H25N3O3S2/c1-27-9-8-17(19(24)25)22-18(23)15-6-2-5-14-13(15)4-3-7-16(14)21-10-12(20)11-26/h2-7,12,17,21,26H,8-11,20H2,1H3,(H,22,23)(H,24,25)/t12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058200 ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) Show SMILES CSCC[C@H](NC(=S)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C22H34N4O4S3/c1-13(2)18(26-19(27)15(23)12-31)20(28)24-17(11-14-7-5-4-6-8-14)21(32)25-16(22(29)30)9-10-33-3/h4-8,13,15-18,31H,9-12,23H2,1-3H3,(H,24,28)(H,25,32)(H,26,27)(H,29,30)/t15-,16-,17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058204 ((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](NC(=O)c1cccc2cc(NC[C@@H](N)CS)ccc12)C(O)=O Show InChI InChI=1S/C19H25N3O3S2/c1-27-8-7-17(19(24)25)22-18(23)16-4-2-3-12-9-14(5-6-15(12)16)21-10-13(20)11-26/h2-6,9,13,17,21,26H,7-8,10-11,20H2,1H3,(H,22,23)(H,24,25)/t13-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ki-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50403479 (CHEMBL2115457) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)[C@H](S)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C28H44N6O6S2/c1-16(2)22(32-25(37)26(41)33-23(35)19(30)10-6-7-12-29)27(38)34-15-18-9-5-4-8-17(18)14-21(34)24(36)31-20(28(39)40)11-13-42-3/h4-5,8-9,16,19-22,26,41H,6-7,10-15,29-30H2,1-3H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20-,21-,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50059852 ((S)-2-((S)-2-((S)-2-((R)-2-amino-3-mercaptopropyla...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C22H38N4O3S2/c1-15(2)20(24-12-17(23)14-30)13-25-19(11-16-7-5-4-6-8-16)21(27)26-18(22(28)29)9-10-31-3/h4-8,15,17-20,24-25,30H,9-14,23H2,1-3H3,(H,26,27)(H,28,29)/t17-,18+,19+,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibiion of bovine farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50284165 ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propyl...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C22H36N4O4S2/c1-14(2)19(24-12-16(23)13-31)21(28)26-18(11-15-7-5-4-6-8-15)20(27)25-17(22(29)30)9-10-32-3/h4-8,14,16-19,24,31H,9-13,23H2,1-3H3,(H,25,27)(H,26,28)(H,29,30)/t16-,17+,18+,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase in NIH3T3 cell based assay under reducing (+DTT) conditions				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50421411 (CHEMBL2304168) Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](OCc3ccc(Cl)cc3)C34[C@H]5C[C@@H](C(C)(C)C)[C@@]33[C@@H](O)C(=O)O[C@H]3O[C@@]4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C27H29ClO10/c1-11-19(30)36-18-17(34-10-12-5-7-13(28)8-6-12)25-15-9-14(23(2,3)4)24(25)16(29)20(31)37-22(24)38-27(25,21(32)35-15)26(11,18)33/h5-8,11,14-18,22,29,33H,9-10H2,1-4H3/t11-,14+,15-,16+,17+,18+,22+,24+,25?,26-,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Compound was evaluated for anti-platelet activating factor potency				Bioorg Med Chem Lett 8: 1291-6 (1999) BindingDB Entry DOI: 10.7270/Q2VH5PB6
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM13373 ((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C22H34N4O5S2/c1-13(2)18(26-19(27)15(23)12-32)21(29)25-17(11-14-7-5-4-6-8-14)20(28)24-16(22(30)31)9-10-33-3/h4-8,13,15-18,32H,9-12,23H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)(H,30,31)/t15-,16-,17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50421412 (CHEMBL2304167) Show SMILES CC1C(=O)O[C@H]2[C@H](O)C34[C@H]5C[C@@H](C(C)(C)C)[C@]33[C@@H](OC(=O)[C@@H]3OCOCc3ccccc3)O[C@@]4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C28H32O11/c1-13-20(30)37-18-17(29)26-16-10-15(24(2,3)4)25(26)19(35-12-34-11-14-8-6-5-7-9-14)21(31)38-23(25)39-28(26,22(32)36-16)27(13,18)33/h5-9,13,15-19,23,29,33H,10-12H2,1-4H3/t13?,15-,16+,17-,18-,19-,23-,25-,26?,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Compound was evaluated for anti-platelet activating factor potency				Bioorg Med Chem Lett 8: 1291-6 (1999) BindingDB Entry DOI: 10.7270/Q2VH5PB6
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284951 ((S)-2-[((S)-2-{(S)-2-[(S)-2-((R)-2,6-Diamino-hexan...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)C(C)(C)C)C(O)=O Show InChI InChI=1S/C29H46N6O6S2/c1-29(2,3)22(33-25(38)26(42)34-23(36)19(31)11-7-8-13-30)27(39)35-16-18-10-6-5-9-17(18)15-21(35)24(37)32-20(28(40)41)12-14-43-4/h5-6,9-10,19-22,26,42H,7-8,11-16,30-31H2,1-4H3,(H,32,37)(H,33,38)(H,34,36)(H,40,41)/t19-,20+,21+,22-,26+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058195 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CCCC[C@H](NC(=O)c1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C20H27N3O3S/c1-2-3-9-18(20(25)26)23-19(24)16-8-4-7-15-14(16)6-5-10-17(15)22-11-13(21)12-27/h4-8,10,13,18,22,27H,2-3,9,11-12,21H2,1H3,(H,23,24)(H,25,26)/t13-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058198 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propionylamino)-...) Show SMILES CSCC[C@H](NC(=O)c1cccc2c(NC(=O)[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C19H23N3O4S2/c1-28-9-8-16(19(25)26)22-17(23)13-6-2-5-12-11(13)4-3-7-15(12)21-18(24)14(20)10-27/h2-7,14,16,27H,8-10,20H2,1H3,(H,21,24)(H,22,23)(H,25,26)/t14-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285838 (CHEMBL89836 | Pseudopeptide derivative) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CNCCSSCCNCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCSC)C(O)=O)C(O)=O Show InChI InChI=1S/C38H52N6O8S4/c1-53-15-11-29(37(49)50)41-35(47)31-19-25-7-3-5-9-27(25)23-43(31)33(45)21-39-13-17-55-56-18-14-40-22-34(46)44-24-28-10-6-4-8-26(28)20-32(44)36(48)42-30(38(51)52)12-16-54-2/h3-10,29-32,39-40H,11-24H2,1-2H3,(H,41,47)(H,42,48)(H,49,50)(H,51,52)/t29-,30-,31-,32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM13373 ((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C22H34N4O5S2/c1-13(2)18(26-19(27)15(23)12-32)21(29)25-17(11-14-7-5-4-6-8-14)20(28)24-16(22(30)31)9-10-33-3/h4-8,13,15-18,32H,9-12,23H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)(H,30,31)/t15-,16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibiion of bovine farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50421410 (CHEMBL2304166) Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](OCOCc3ccccc3)C34[C@H]5C[C@@H](C(C)(C)C)[C@@]33[C@@H](O)C(=O)O[C@H]3O[C@@]4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C28H32O11/c1-13-20(30)37-19-18(35-12-34-11-14-8-6-5-7-9-14)26-16-10-15(24(2,3)4)25(26)17(29)21(31)38-23(25)39-28(26,22(32)36-16)27(13,19)33/h5-9,13,15-19,23,29,33H,10-12H2,1-4H3/t13-,15+,16-,17+,18+,19+,23+,25+,26?,27-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Compound was evaluated for anti-platelet activating factor potency				Bioorg Med Chem Lett 8: 1291-6 (1999) BindingDB Entry DOI: 10.7270/Q2VH5PB6
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058197 ((S)-2-{[6-((R)-2-Amino-3-mercapto-propionylamino)-...) Show SMILES CSCC[C@H](NC(=O)c1cccc2cc(NC(=O)[C@@H](N)CS)ccc12)C(O)=O Show InChI InChI=1S/C19H23N3O4S2/c1-28-8-7-16(19(25)26)22-17(23)14-4-2-3-11-9-12(5-6-13(11)14)21-18(24)15(20)10-27/h2-6,9,15-16,27H,7-8,10,20H2,1H3,(H,21,24)(H,22,23)(H,25,26)/t15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM13373 ((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C22H34N4O5S2/c1-13(2)18(26-19(27)15(23)12-32)21(29)25-17(11-14-7-5-4-6-8-14)20(28)24-16(22(30)31)9-10-33-3/h4-8,13,15-18,32H,9-12,23H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)(H,30,31)/t15-,16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase in NIH3T3 cell based assay in non-reducing (-DTT) conditions				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058193 ((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES COC(=O)[C@H](CCSC)NC(=O)c1cccc2cc(NC[C@@H](N)CS)ccc12 Show InChI InChI=1S/C20H27N3O3S2/c1-26-20(25)18(8-9-28-2)23-19(24)17-5-3-4-13-10-15(6-7-16(13)17)22-11-14(21)12-27/h3-7,10,14,18,22,27H,8-9,11-12,21H2,1-2H3,(H,23,24)/t14-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285846 ((S)-2-({(S)-2-[2-(2-Mercapto-ethylamino)-acetyl]-1...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CNCCS)C(O)=O Show InChI InChI=1S/C19H27N3O4S2/c1-28-9-6-15(19(25)26)21-18(24)16-10-13-4-2-3-5-14(13)12-22(16)17(23)11-20-7-8-27/h2-5,15-16,20,27H,6-12H2,1H3,(H,21,24)(H,25,26)/t15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50251276 (BN 52021 | CHEMBL514432 | GINKOLIDE B | Gingkolide...) Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@@]33[C@@H](O)C(=O)O[C@H]3O[C@@]4(C(=O)O5)[C@@]12O |r| Show InChI InChI=1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10+,11+,15+,17+,18+,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Compound was evaluated for anti-platelet activating factor potency				Bioorg Med Chem Lett 8: 1291-6 (1999) BindingDB Entry DOI: 10.7270/Q2VH5PB6
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285842 (CHEMBL420801 | Pseudopeptide derivative) Show SMILES COC(=O)[C@H](CCSC)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CNCCSSCCNCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCSC)C(=O)OC Show InChI InChI=1S/C40H56N6O8S4/c1-53-39(51)31(13-17-55-3)43-37(49)33-21-27-9-5-7-11-29(27)25-45(33)35(47)23-41-15-19-57-58-20-16-42-24-36(48)46-26-30-12-8-6-10-28(30)22-34(46)38(50)44-32(14-18-56-4)40(52)54-2/h5-12,31-34,41-42H,13-26H2,1-4H3,(H,43,49)(H,44,50)/t31-,32-,33-,34-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058207 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](N(C)C(=O)c1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C20H27N3O3S2/c1-23(18(20(25)26)9-10-28-2)19(24)16-7-3-6-15-14(16)5-4-8-17(15)22-11-13(21)12-27/h3-8,13,18,22,27H,9-12,21H2,1-2H3,(H,25,26)/t13-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285837 ((S)-2-({(S)-2-[2-(2-Mercapto-ethylamino)-acetyl]-1...) Show SMILES COC(=O)[C@H](CCSC)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CNCCS Show InChI InChI=1S/C20H29N3O4S2/c1-27-20(26)16(7-10-29-2)22-19(25)17-11-14-5-3-4-6-15(14)13-23(17)18(24)12-21-8-9-28/h3-6,16-17,21,28H,7-13H2,1-2H3,(H,22,25)/t16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058196 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES COC(=O)[C@H](CCSC)NC(=O)c1cccc2c(NC[C@@H](N)CS)cccc12 Show InChI InChI=1S/C20H27N3O3S2/c1-26-20(25)18(9-10-28-2)23-19(24)16-7-3-6-15-14(16)5-4-8-17(15)22-11-13(21)12-27/h3-8,13,18,22,27H,9-12,21H2,1-2H3,(H,23,24)/t13-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058193 ((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES COC(=O)[C@H](CCSC)NC(=O)c1cccc2cc(NC[C@@H](N)CS)ccc12 Show InChI InChI=1S/C20H27N3O3S2/c1-26-20(25)18(8-9-28-2)23-19(24)17-5-3-4-13-10-15(6-7-16(13)17)22-11-14(21)12-27/h3-7,10,14,18,22,27H,8-9,11-12,21H2,1-2H3,(H,23,24)/t14-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ki-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058205 ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) Show SMILES CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C23H36N4O5S/c1-4-5-11-17(23(31)32)25-21(29)18(12-15-9-7-6-8-10-15)26-22(30)19(14(2)3)27-20(28)16(24)13-33/h6-10,14,16-19,33H,4-5,11-13,24H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)(H,31,32)/t16-,17-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM13373 ((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C22H34N4O5S2/c1-13(2)18(26-19(27)15(23)12-32)21(29)25-17(11-14-7-5-4-6-8-14)20(28)24-16(22(30)31)9-10-33-3/h4-8,13,15-18,32H,9-12,23H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)(H,30,31)/t15-,16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Human farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284950 ((S)-2-((S)-2-{(S)-2-[(S)-2-((R)-2,6-Diamino-hexano...) Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)C(C)(C)C)c1ccccc1)C(O)=O Show InChI InChI=1S/C27H44N6O6S2/c1-27(2,3)20(32-24(37)25(40)33-21(34)17(29)12-8-9-14-28)23(36)31-19(16-10-6-5-7-11-16)22(35)30-18(26(38)39)13-15-41-4/h5-7,10-11,17-20,25,40H,8-9,12-15,28-29H2,1-4H3,(H,30,35)(H,31,36)(H,32,37)(H,33,34)(H,38,39)/t17-,18+,19+,20-,25+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284953 ((S)-2-[(S)-2-((S)-2-{[(S)-2-((R)-2,6-Diamino-hexan...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)C(O)=O Show InChI InChI=1S/C28H46N6O6S2/c1-17(2)22(34(3)27(38)26(41)33-23(35)19(30)12-8-9-14-29)25(37)32-21(16-18-10-6-5-7-11-18)24(36)31-20(28(39)40)13-15-42-4/h5-7,10-11,17,19-22,26,41H,8-9,12-16,29-30H2,1-4H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20+,21+,22+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284948 ((S)-2-[(S)-2-((S)-2-{[(S)-2-((R)-2,6-Diamino-hexan...) Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)c1ccccc1)C(O)=O Show InChI InChI=1S/C27H44N6O6S2/c1-16(2)21(33(3)26(37)25(40)32-22(34)18(29)12-8-9-14-28)24(36)31-20(17-10-6-5-7-11-17)23(35)30-19(27(38)39)13-15-41-4/h5-7,10-11,16,18-21,25,40H,8-9,12-15,28-29H2,1-4H3,(H,30,35)(H,31,36)(H,32,34)(H,38,39)/t18-,19+,20+,21+,25+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284952 ((S)-2-((S)-2-{(S)-2-[(S)-2-((R)-2,6-Diamino-hexano...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C27H44N6O6S2/c1-16(2)21(32-25(37)26(40)33-22(34)18(29)11-7-8-13-28)24(36)31-20(15-17-9-5-4-6-10-17)23(35)30-19(27(38)39)12-14-41-3/h4-6,9-10,16,18-21,26,40H,7-8,11-15,28-29H2,1-3H3,(H,30,35)(H,31,36)(H,32,37)(H,33,34)(H,38,39)/t18-,19+,20+,21+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058197 ((S)-2-{[6-((R)-2-Amino-3-mercapto-propionylamino)-...) Show SMILES CSCC[C@H](NC(=O)c1cccc2cc(NC(=O)[C@@H](N)CS)ccc12)C(O)=O Show InChI InChI=1S/C19H23N3O4S2/c1-28-8-7-16(19(25)26)22-17(23)14-4-2-3-11-9-12(5-6-13(11)14)21-18(24)15(20)10-27/h2-6,9,15-16,27H,7-8,10,20H2,1H3,(H,21,24)(H,22,23)(H,25,26)/t15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ki-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058206 ((S)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propi...) Show SMILES CSCC[C@H](N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C23H36N4O5S2/c1-14(2)19(26-20(28)16(24)13-33)21(29)25-17(12-15-8-6-5-7-9-15)22(30)27(3)18(23(31)32)10-11-34-4/h5-9,14,16-19,33H,10-13,24H2,1-4H3,(H,25,29)(H,26,28)(H,31,32)/t16-,17-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285845 (2-({2-[(2-Mercapto-ethylcarbamoyl)-methyl]-1,2,3,4...) Show SMILES CSCCC(NC(=O)C1Cc2ccccc2CN1CC(=O)NCCS)C(O)=O Show InChI InChI=1S/C19H27N3O4S2/c1-28-9-6-15(19(25)26)21-18(24)16-10-13-4-2-3-5-14(13)11-22(16)12-17(23)20-7-8-27/h2-5,15-16,27H,6-12H2,1H3,(H,20,23)(H,21,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50403478 (CHEMBL2115458) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H]1CCCN1C(=O)[C@H](S)NC(=O)[C@@H](N)CCCCN)C(O)=O Show InChI InChI=1S/C28H42N6O6S2/c1-42-14-11-20(28(39)40)31-24(36)22-15-17-7-2-3-8-18(17)16-34(22)26(37)21-10-6-13-33(21)27(38)25(41)32-23(35)19(30)9-4-5-12-29/h2-3,7-8,19-22,25,41H,4-6,9-16,29-30H2,1H3,(H,31,36)(H,32,35)(H,39,40)/t19-,20-,21-,22-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058203 ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) Show SMILES CSCC[C@H](NC[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C22H36N4O4S2/c1-14(2)19(26-20(27)17(23)13-31)21(28)25-16(11-15-7-5-4-6-8-15)12-24-18(22(29)30)9-10-32-3/h4-8,14,16-19,24,31H,9-13,23H2,1-3H3,(H,25,28)(H,26,27)(H,29,30)/t16-,17-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058194 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...) Show SMILES CSCC[C@H](NCc1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O Show InChI InChI=1S/C19H27N3O2S2/c1-26-9-8-18(19(23)24)21-10-13-4-2-6-16-15(13)5-3-7-17(16)22-11-14(20)12-25/h2-7,14,18,21-22,25H,8-12,20H2,1H3,(H,23,24)/t14-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50058201 ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...) Show SMILES COC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C Show InChI InChI=1S/C23H36N4O5S2/c1-14(2)19(27-20(28)16(24)13-33)22(30)26-18(12-15-8-6-5-7-9-15)21(29)25-17(10-11-34-4)23(31)32-3/h5-9,14,16-19,33H,10-13,24H2,1-4H3,(H,25,29)(H,26,30)(H,27,28)/t16-,17-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferase				J Med Chem 40: 1763-7 (1997) Article DOI: 10.1021/jm9701177 BindingDB Entry DOI: 10.7270/Q2J1029S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50403477 (CHEMBL2115025) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](NC(=O)[C@H](S)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C28H44N6O6S2/c1-16(2)22(32-25(37)26(41)33-23(35)19(30)10-6-7-12-29)27(38)34-15-18-9-5-4-8-17(18)14-21(34)24(36)31-20(28(39)40)11-13-42-3/h4-5,8-9,16,19-22,26,41H,6-7,10-15,29-30H2,1-3H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20-,21-,22+,26-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50403477 (CHEMBL2115025) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](NC(=O)[C@H](S)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C28H44N6O6S2/c1-16(2)22(32-25(37)26(41)33-23(35)19(30)10-6-7-12-29)27(38)34-15-18-9-5-4-8-17(18)14-21(34)24(36)31-20(28(39)40)11-13-42-3/h4-5,8-9,16,19-22,26,41H,6-7,10-15,29-30H2,1-3H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20-,21-,22+,26-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM13373 ((2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C22H34N4O5S2/c1-13(2)18(26-19(27)15(23)12-32)21(29)25-17(11-14-7-5-4-6-8-14)20(28)24-16(22(30)31)9-10-33-3/h4-8,13,15-18,32H,9-12,23H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)(H,30,31)/t15-,16-,17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50213273 (CHEMBL3350692) Show SMILES CSCC[C@H](NC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(O)=O Show InChI InChI=1S/C29H44N6O6S2/c1-43-14-11-21(29(40)41)32-26(37)24-15-18-7-2-3-8-19(18)16-35(24)28(39)23-10-6-13-34(23)27(38)22(17-42)33-25(36)20(31)9-4-5-12-30/h2-3,7-8,20-24,42H,4-6,9-17,30-31H2,1H3,(H,32,37)(H,33,36)(H,40,41)/t20-,21-,22-,23+,24+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50213274 (CHEMBL3350314) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C29H46N6O6S2/c1-17(2)24(34-26(37)22(16-42)33-25(36)20(31)10-6-7-12-30)28(39)35-15-19-9-5-4-8-18(19)14-23(35)27(38)32-21(29(40)41)11-13-43-3/h4-5,8-9,17,20-24,42H,6-7,10-16,30-31H2,1-3H3,(H,32,38)(H,33,36)(H,34,37)(H,40,41)/t20-,21-,22-,23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50213274 (CHEMBL3350314) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C29H46N6O6S2/c1-17(2)24(34-26(37)22(16-42)33-25(36)20(31)10-6-7-12-30)28(39)35-15-19-9-5-4-8-18(19)14-23(35)27(38)32-21(29(40)41)11-13-43-3/h4-5,8-9,17,20-24,42H,6-7,10-16,30-31H2,1-3H3,(H,32,38)(H,33,36)(H,34,37)(H,40,41)/t20-,21-,22-,23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50285843 ((S)-2-[((S)-2-{2-[tert-Butoxycarbonyl-(2-mercapto-...) Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CN(CCS)C(=O)OC(C)(C)C)C(O)=O Show InChI InChI=1S/C24H35N3O6S2/c1-24(2,3)33-23(32)26(10-11-34)15-20(28)27-14-17-8-6-5-7-16(17)13-19(27)21(29)25-18(22(30)31)9-12-35-4/h5-8,18-19,34H,9-15H2,1-4H3,(H,25,29)(H,30,31)/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl transferase				Bioorg Med Chem Lett 5: 2677-2682 (1995) Article DOI: 10.1016/0960-894X(95)00482-9 BindingDB Entry DOI: 10.7270/Q2QC03GF
					More data for this Ligand-Target Pair

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