Compile Data Set for Download or QSAR

Found 13 hits with Last Name = 'höltje' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50120404 (Acetic acid 2-(8-hydroxy-6,11-dimethyl-1,2,5,6-tet...) Show SMILES C[C@H]1C2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1C[C@@]1(COC(C)=O)c1ccccc1 |TLB:9:10:1:15.13.14,THB:16:15:1:10.4.3| Show InChI InChI=1S/C27H33NO3/c1-18-25-13-20-9-10-23(30)14-24(20)26(18,3)11-12-28(25)16-22-15-27(22,17-31-19(2)29)21-7-5-4-6-8-21/h4-10,14,18,22,25,30H,11-13,15-17H2,1-3H3/t18-,22?,25?,26-,27+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	228	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of [3H]-U-69,593 binding towards Opioid receptor kappa 1 in guinea pig brain homogenates.				J Med Chem 45: 4838-46 (2002) BindingDB Entry DOI: 10.7270/Q2765DPP
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50120406 (2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...) Show SMILES C[C@H]1C2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1C[C@@]1(C(=O)Nc1ccccc1)c1ccccc1 |TLB:9:10:1:15.13.14,THB:16:15:1:10.4.3| Show InChI InChI=1S/C31H34N2O2/c1-21-28-17-22-13-14-26(34)18-27(22)30(21,2)15-16-33(28)20-24-19-31(24,23-9-5-3-6-10-23)29(35)32-25-11-7-4-8-12-25/h3-14,18,21,24,28,34H,15-17,19-20H2,1-2H3,(H,32,35)/t21-,24?,28?,30-,31+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of [3H]-U-69,593 binding towards Opioid receptor kappa 1 in guinea pig brain homogenates.				J Med Chem 45: 4838-46 (2002) BindingDB Entry DOI: 10.7270/Q2765DPP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50101397 (2-(2,6-Dichloro-phenyl)-3-(6-methyl-pyridin-2-yl)-...) Show SMILES Cc1cccc(n1)N1C(SCC1=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H12Cl2N2OS/c1-9-4-2-7-12(18-9)19-13(20)8-21-15(19)14-10(16)5-3-6-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50101407 (2-(2,6-Difluoro-phenyl)-3-(4-methyl-pyridin-2-yl)-...) Show SMILES Cc1ccnc(c1)N1C(SCC1=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N2OS/c1-9-5-6-18-12(7-9)19-13(20)8-21-15(19)14-10(16)3-2-4-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121354 (2-(2-Fluoro-6-methyl-phenyl)-3-(6-methyl-pyridin-2...) Show SMILES Cc1cccc(n1)N1C(SCC1=O)c1c(C)cccc1F Show InChI InChI=1S/C16H15FN2OS/c1-10-5-3-7-12(17)15(10)16-19(14(20)9-21-16)13-8-4-6-11(2)18-13/h3-8,16H,9H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50101404 (2-(2,6-Difluoro-phenyl)-3-(6-methyl-pyridin-2-yl)-...) Show SMILES Cc1cccc(n1)N1C(SCC1=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N2OS/c1-9-4-2-7-12(18-9)19-13(20)8-21-15(19)14-10(16)5-3-6-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121357 (2-(2,6-Difluoro-phenyl)-3-(4,6-dimethyl-pyridin-2-...) Show SMILES Cc1cc(C)nc(c1)N1C(SCC1=O)c1c(F)cccc1F Show InChI InChI=1S/C16H14F2N2OS/c1-9-6-10(2)19-13(7-9)20-14(21)8-22-16(20)15-11(17)4-3-5-12(15)18/h3-7,16H,8H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121350 (2-(2-Chloro-6-fluoro-phenyl)-3-(4-methyl-pyridin-2...) Show SMILES Cc1ccnc(c1)N1C(SCC1=O)c1c(F)cccc1Cl Show InChI InChI=1S/C15H12ClFN2OS/c1-9-5-6-18-12(7-9)19-13(20)8-21-15(19)14-10(16)3-2-4-11(14)17/h2-7,15H,8H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121347 (CHEMBL625 | THIABENDAZOLE) Show SMILES c1nc(cs1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121352 (2-(2-Chloro-6-methyl-phenyl)-3-(5-methyl-pyridin-2...) Show SMILES Cc1ccc(nc1)N1C(SCC1=O)c1c(C)cccc1Cl Show InChI InChI=1S/C16H15ClN2OS/c1-10-6-7-13(18-8-10)19-14(20)9-21-16(19)15-11(2)4-3-5-12(15)17/h3-8,16H,9H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121351 (3-(5-Bromo-pyridin-2-yl)-2-(2,6-dichloro-phenyl)-t...) Show SMILES Clc1cccc(Cl)c1C1SCC(=O)N1c1ccc(Br)cn1 Show InChI InChI=1S/C14H9BrCl2N2OS/c15-8-4-5-11(18-6-8)19-12(20)7-21-14(19)13-9(16)2-1-3-10(13)17/h1-6,14H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121356 (3-(5-Bromo-pyridin-2-yl)-2-(2,6-difluoro-phenyl)-t...) Show SMILES Fc1cccc(F)c1C1SCC(=O)N1c1ccc(Br)cn1 Show InChI InChI=1S/C14H9BrF2N2OS/c15-8-4-5-11(18-6-8)19-12(20)7-21-14(19)13-9(16)2-1-3-10(13)17/h1-6,14H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50121353 (3-(5-Chloro-pyridin-2-yl)-2-(2,6-difluoro-phenyl)-...) Show SMILES Fc1cccc(F)c1C1SCC(=O)N1c1ccc(Cl)cn1 Show InChI InChI=1S/C14H9ClF2N2OS/c15-8-4-5-11(18-6-8)19-12(20)7-21-14(19)13-9(16)2-1-3-10(13)17/h1-6,14H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description HIV-1 reverse transcriptase (RT) activity using Poly (rC)/oligo (dG) as template/primer and [3H]dGTP				J Med Chem 45: 5410-3 (2002) BindingDB Entry DOI: 10.7270/Q2TT4Q9K
					More data for this Ligand-Target Pair