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Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'hahn' and Initial = 'ra'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50222264
PNG
(CHEMBL552736)
Show SMILES Br.CN1CCc2cc(O)c(O)c(Sc3ccccc3)c2CC1
Show InChI InChI=1S/C17H19NO2S/c1-18-9-7-12-11-15(19)16(20)17(14(12)8-10-18)21-13-5-3-2-4-6-13/h2-6,11,19-20H,7-10H2,1H3
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 22n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50222266
PNG
(CHEMBL369006)
Show SMILES CN1CCc2c(Cl)c(O)c(O)c(Sc3ccccc3)c2CC1
Show InChI InChI=1S/C17H18ClNO2S/c1-19-9-7-12-13(8-10-19)17(16(21)15(20)14(12)18)22-11-5-3-2-4-6-11/h2-6,20-21H,7-10H2,1H3
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 33n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50001888
PNG
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
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 118n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50222265
PNG
(CHEMBL541633)
Show SMILES Br.Oc1cc2CCNCCc2c(Sc2ccccc2)c1O
Show InChI InChI=1S/C16H17NO2S/c18-14-10-11-6-8-17-9-7-13(11)16(15(14)19)20-12-4-2-1-3-5-12/h1-5,10,17-19H,6-9H2
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 250n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50017543
PNG
((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Show SMILES CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 |r|
Show InChI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
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n/an/a 1.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50017543
PNG
((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Show SMILES CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 |r|
Show InChI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
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n/an/a 4.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]dopamine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50017543
PNG
((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Show SMILES CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 |r|
Show InChI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
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n/an/a 48n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 240n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50222264
PNG
(CHEMBL552736)
Show SMILES Br.CN1CCc2cc(O)c(O)c(Sc3ccccc3)c2CC1
Show InChI InChI=1S/C17H19NO2S/c1-18-9-7-12-11-15(19)16(20)17(14(12)8-10-18)21-13-5-3-2-4-6-13/h2-6,11,19-20H,7-10H2,1H3
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n/an/a 240n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50222266
PNG
(CHEMBL369006)
Show SMILES CN1CCc2c(Cl)c(O)c(O)c(Sc3ccccc3)c2CC1
Show InChI InChI=1S/C17H18ClNO2S/c1-19-9-7-12-13(8-10-19)17(16(21)15(20)14(12)18)22-11-5-3-2-4-6-11/h2-6,20-21H,7-10H2,1H3
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n/an/a 360n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
Adenylate cyclase type 1/Adenylate cyclase type 2/Adenylate cyclase type 3/Adenylate cyclase type 4/Adenylate cyclase type 5/Adenylate cyclase type 6/Adenylate cyclase type 8/Adenylyl cyclase 7


(Rattus norvegicus-RAT)		BDBM50001888
PNG
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50222265
PNG
(CHEMBL541633)
Show SMILES Br.Oc1cc2CCNCCc2c(Sc2ccccc2)c1O
Show InChI InChI=1S/C16H17NO2S/c18-14-10-11-6-8-17-9-7-13(11)16(15(14)19)20-12-4-2-1-3-5-12/h1-5,10,17-19H,6-9H2
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n/an/a 2.70E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Dopamine sensitive adenylate cyclase in rats

J Med Chem 23: 975-6 (1980)


BindingDB Entry DOI: 10.7270/Q2RV0QWD
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 3.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 3.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/a 5.34E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-spiperone binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]dopamine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]dopamine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-spiperone binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]dopamine binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50224978
PNG
(CHEMBL417076)
Show SMILES [H][C@]12CCCN(CCC)C1Cc1c[nH]nc1C2 |r|
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-spiperone binding to dopamine receptor of rat corpus striatum

J Med Chem 26: 1112-6 (1983)


BindingDB Entry DOI: 10.7270/Q29G5Q18
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50004822
PNG
((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...)
Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1
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n/an/a 3.39E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50004923
PNG
((+/-)-SKF-38393 | 1-Phenyl-2,3,4,5-tetrahydro-1H-b...)
Show SMILES Oc1cc2CCNCC(c3ccccc3)c2cc1O
Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2
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n/an/a 3.44E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50004920
PNG
(CHEMBL284746 | S(-)SKF 383931-Phenyl-2,3,4,5-tetra...)
Show SMILES Oc1cc2CCNC[C@@H](c3ccccc3)c2cc1O
Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m0/s1
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n/an/a 1.97E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50020686
PNG
(4-(2-Amino-ethyl)-7-hydroxy-1,3-dihydro-indol-2-on...)
Show SMILES NCCc1ccc(O)c2NC(=O)Cc12
Show InChI InChI=1S/C10H12N2O2/c11-4-3-6-1-2-8(13)10-7(6)5-9(14)12-10/h1-2,13H,3-5,11H2,(H,12,14)
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n/an/an/an/a 116n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 3 ug/kg

J Med Chem 26: 933-5 (1983)


BindingDB Entry DOI: 10.7270/Q2F76FRK
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50019396
PNG
(4-(2-Dipropylamino-ethyl)-benzene-1,2-diol | 4-(2-...)
Show SMILES CCCN(CCC)CCc1ccc(O)c(O)c1
Show InChI InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3
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n/an/an/an/a 80n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 3 mg/kg

J Med Chem 26: 933-5 (1983)


BindingDB Entry DOI: 10.7270/Q2F76FRK
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50019389
PNG
(3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...)
Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12
Show InChI InChI=1S/C19H20ClNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2
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n/an/an/an/a 122n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 0.3 mg/kg

J Med Chem 26: 933-5 (1983)


BindingDB Entry DOI: 10.7270/Q2F76FRK
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50019393
PNG
(4-(2-Dipropylamino-ethyl)-7-hydroxy-1,3-dihydro-in...)
Show SMILES CCCN(CCC)CCc1ccc(O)c2NC(=O)Cc12
Show InChI InChI=1S/C16H24N2O2/c1-3-8-18(9-4-2)10-7-12-5-6-14(19)16-13(12)11-15(20)17-16/h5-6,19H,3-4,7-11H2,1-2H3,(H,17,20)
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n/an/an/an/a 1.80n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 0.3 mg/kg

J Med Chem 26: 933-5 (1983)


BindingDB Entry DOI: 10.7270/Q2F76FRK
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50004822
PNG
((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...)
Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1
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n/an/an/an/a 32n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM50004923
PNG
((+/-)-SKF-38393 | 1-Phenyl-2,3,4,5-tetrahydro-1H-b...)
Show SMILES Oc1cc2CCNCC(c3ccccc3)c2cc1O
Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2
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n/an/an/an/a 71n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair
Adenylate cyclase type 1


(Rattus norvegicus)		BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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n/an/an/an/a 3.50E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells

J Med Chem 25: 697-703 (1982)


BindingDB Entry DOI: 10.7270/Q2154K7B
More data for this
Ligand-Target Pair