Compile Data Set for Download or QSAR

Found 94 hits with Last Name = 'hellinger'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM85097 (CAS_181632-25-7 | CHEMBL14563 | SB 242084) Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Cl Show InChI InChI=1S/C21H19ClN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140071 (CHEMBL3752465) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cc1)c1ccccc1 Show InChI InChI=1S/C27H30ClN3O2/c1-19-17-21-13-16-31(25(21)18-24(19)28)27(32)29-22-9-11-23(12-10-22)33-26(14-15-30(2)3)20-7-5-4-6-8-20/h4-12,17-18,26H,13-16H2,1-3H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013050 (CHEMBL3261693) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc(C)c(Cl)c2)cc1)c1ccccc1 Show InChI InChI=1S/C25H28ClN3O2/c1-18-9-10-21(17-23(18)26)28-25(30)27-20-11-13-22(14-12-20)31-24(15-16-29(2)3)19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013071 (CHEMBL3261688) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3ccccc3c2)cc1)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c1-31(2)19-18-27(22-9-4-3-5-10-22)33-26-16-14-24(15-17-26)29-28(32)30-25-13-12-21-8-6-7-11-23(21)20-25/h3-17,20,27H,18-19H2,1-2H3,(H2,29,30,32)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50140065 (CHEMBL3753894) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H21IN2O2S/c1-19(2)12-13-20(14-15-6-4-3-5-7-15)23(21,22)17-10-8-16(18)9-11-17/h3-11H,12-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to 5HT2A (unknown origin)				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013051 (CHEMBL3261694) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc(C)c(I)c2)cc1)c1ccccc1 Show InChI InChI=1S/C25H28IN3O2/c1-18-9-10-21(17-23(18)26)28-25(30)27-20-11-13-22(14-12-20)31-24(15-16-29(2)3)19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013112 (CHEMBL3261704) Show SMILES COc1cc(NC(=O)Nc2ccc(Cl)c(Cl)c2)ccc1OC(CCN(C)C)c1ccccc1 Show InChI InChI=1S/C25H27Cl2N3O3/c1-30(2)14-13-22(17-7-5-4-6-8-17)33-23-12-10-19(16-24(23)32-3)29-25(31)28-18-9-11-20(26)21(27)15-18/h4-12,15-16,22H,13-14H2,1-3H3,(H2,28,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013103 (CHEMBL3261692) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1)c1ccccc1 Show InChI InChI=1S/C24H25Cl2N3O2/c1-29(2)15-14-23(17-6-4-3-5-7-17)31-20-11-8-18(9-12-20)27-24(30)28-19-10-13-21(25)22(26)16-19/h3-13,16,23H,14-15H2,1-2H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013050 (CHEMBL3261693) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc(C)c(Cl)c2)cc1)c1ccccc1 Show InChI InChI=1S/C25H28ClN3O2/c1-18-9-10-21(17-23(18)26)28-25(30)27-20-11-13-22(14-12-20)31-24(15-16-29(2)3)19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50140065 (CHEMBL3753894) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H21IN2O2S/c1-19(2)12-13-20(14-15-6-4-3-5-7-15)23(21,22)17-10-8-16(18)9-11-17/h3-11H,12-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A in Wistar rat frontal cortex membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013053 (CHEMBL3261696) Show SMILES COc1ccc(NC(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)cc1C(F)(F)F Show InChI InChI=1S/C26H28F3N3O3/c1-32(2)16-15-23(18-7-5-4-6-8-18)35-21-12-9-19(10-13-21)30-25(33)31-20-11-14-24(34-3)22(17-20)26(27,28)29/h4-14,17,23H,15-16H2,1-3H3,(H2,30,31,33)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013104 (CHEMBL3261697) Show SMILES CSc1ccc(NC(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)cc1C(F)(F)F Show InChI InChI=1S/C26H28F3N3O2S/c1-32(2)16-15-23(18-7-5-4-6-8-18)34-21-12-9-19(10-13-21)30-25(33)31-20-11-14-24(35-3)22(17-20)26(27,28)29/h4-14,17,23H,15-16H2,1-3H3,(H2,30,31,33)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013117 (CHEMBL3261691) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3nccn3c2)cc1)c1ccccc1 Show InChI InChI=1S/C25H27N5O2/c1-29(2)16-14-23(19-6-4-3-5-7-19)32-22-11-8-20(9-12-22)27-25(31)28-21-10-13-24-26-15-17-30(24)18-21/h3-13,15,17-18,23H,14,16H2,1-2H3,(H2,27,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140069 (CHEMBL3753329) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(NC(=O)Nc2ccc(C)c(Cl)c2)cc1 Show InChI InChI=1S/C25H29ClN4O3S/c1-19-9-10-22(17-24(19)26)28-25(31)27-21-11-13-23(14-12-21)34(32,33)30(16-15-29(2)3)18-20-7-5-4-6-8-20/h4-14,17H,15-16,18H2,1-3H3,(H2,27,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM30130 (CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...) Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140066 (CHEMBL3754784) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1cccc(c1)N1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C27H33ClN4O2S/c1-29(2)14-19-32(22-23-8-4-3-5-9-23)35(33,34)27-13-7-12-26(21-27)31-17-15-30(16-18-31)25-11-6-10-24(28)20-25/h3-13,20-21H,14-19,22H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013079 (CHEMBL3261689) Show SMILES O=C(Nc1cccnc1)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C16H13N3O/c20-16(19-15-6-3-9-17-11-15)18-14-8-7-12-4-1-2-5-13(12)10-14/h1-11H,(H2,18,19,20)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50140065 (CHEMBL3753894) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H21IN2O2S/c1-19(2)12-13-20(14-15-6-4-3-5-7-15)23(21,22)17-10-8-16(18)9-11-17/h3-11H,12-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to 5HT2C (unknown origin)				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140067 (CHEMBL3753681) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C27H33ClN4O2S/c1-29(2)15-20-32(22-23-7-4-3-5-8-23)35(33,34)27-13-11-25(12-14-27)30-16-18-31(19-17-30)26-10-6-9-24(28)21-26/h3-14,21H,15-20,22H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013069 (CHEMBL3261686) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3n(C)ccc3c2)cc1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)17-16-26(20-7-5-4-6-8-20)33-24-12-9-22(10-13-24)28-27(32)29-23-11-14-25-21(19-23)15-18-31(25)3/h4-15,18-19,26H,16-17H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013069 (CHEMBL3261686) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3n(C)ccc3c2)cc1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)17-16-26(20-7-5-4-6-8-20)33-24-12-9-22(10-13-24)28-27(32)29-23-11-14-25-21(19-23)15-18-31(25)3/h4-15,18-19,26H,16-17H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013056 (CHEMBL3261699) Show SMILES CN(C)CCC(Oc1cccc(NC(=O)Nc2ccc3n(C)ccc3c2)c1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)16-15-26(20-8-5-4-6-9-20)33-24-11-7-10-22(19-24)28-27(32)29-23-12-13-25-21(18-23)14-17-31(25)3/h4-14,17-19,26H,15-16H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50140067 (CHEMBL3753681) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C27H33ClN4O2S/c1-29(2)15-20-32(22-23-7-4-3-5-8-23)35(33,34)27-13-11-25(12-14-27)30-16-18-31(19-17-30)26-10-6-9-24(28)21-26/h3-14,21H,15-20,22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A in Wistar rat frontal cortex membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013065 (CHEMBL3261703) Show SMILES CN(C)CCC(Oc1ccc(cc1)N1CCN(C1=O)c1ccc(Cl)c(Cl)c1)c1ccccc1 Show InChI InChI=1S/C26H27Cl2N3O2/c1-29(2)15-14-25(19-6-4-3-5-7-19)33-22-11-8-20(9-12-22)30-16-17-31(26(30)32)21-10-13-23(27)24(28)18-21/h3-13,18,25H,14-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013070 (CHEMBL3261687) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3ccn(C)c3c2)cc1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)17-16-26(21-7-5-4-6-8-21)33-24-13-11-22(12-14-24)28-27(32)29-23-10-9-20-15-18-31(3)25(20)19-23/h4-15,18-19,26H,16-17H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013102 (CHEMBL3261690) Show SMILES CCn1ccc2cc(NC(=O)Nc3ccc(OC(CCN(C)C)c4ccccc4)cc3)ccc12 Show InChI InChI=1S/C28H32N4O2/c1-4-32-19-16-22-20-24(12-15-26(22)32)30-28(33)29-23-10-13-25(14-11-23)34-27(17-18-31(2)3)21-8-6-5-7-9-21/h5-16,19-20,27H,4,17-18H2,1-3H3,(H2,29,30,33)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013052 (CHEMBL3261695) Show SMILES COc1ccc(NC(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)cc1Cl Show InChI InChI=1S/C25H28ClN3O3/c1-29(2)16-15-23(18-7-5-4-6-8-18)32-21-12-9-19(10-13-21)27-25(30)28-20-11-14-24(31-3)22(26)17-20/h4-14,17,23H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013052 (CHEMBL3261695) Show SMILES COc1ccc(NC(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)cc1Cl Show InChI InChI=1S/C25H28ClN3O3/c1-29(2)16-15-23(18-7-5-4-6-8-18)32-21-12-9-19(10-13-21)27-25(30)28-20-11-14-24(31-3)22(26)17-20/h4-14,17,23H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013102 (CHEMBL3261690) Show SMILES CCn1ccc2cc(NC(=O)Nc3ccc(OC(CCN(C)C)c4ccccc4)cc3)ccc12 Show InChI InChI=1S/C28H32N4O2/c1-4-32-19-16-22-20-24(12-15-26(22)32)30-28(33)29-23-10-13-25(14-11-23)34-27(17-18-31(2)3)21-8-6-5-7-9-21/h5-16,19-20,27H,4,17-18H2,1-3H3,(H2,29,30,33)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140065 (CHEMBL3753894) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H21IN2O2S/c1-19(2)12-13-20(14-15-6-4-3-5-7-15)23(21,22)17-10-8-16(18)9-11-17/h3-11H,12-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140064 (CHEMBL3752844) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(NC(=O)Nc2ccc3n(C)ccc3c2)cc1 Show InChI InChI=1S/C27H31N5O3S/c1-30(2)17-18-32(20-21-7-5-4-6-8-21)36(34,35)25-12-9-23(10-13-25)28-27(33)29-24-11-14-26-22(19-24)15-16-31(26)3/h4-16,19H,17-18,20H2,1-3H3,(H2,28,29,33)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013069 (CHEMBL3261686) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3n(C)ccc3c2)cc1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)17-16-26(20-7-5-4-6-8-20)33-24-12-9-22(10-13-24)28-27(32)29-23-11-14-25-21(19-23)15-18-31(25)3/h4-15,18-19,26H,16-17H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013067 (CHEMBL3261707) Show SMILES COc1ccc(cc1Cl)C(=O)Nc1ccc(OC(CCN(C)C)c2ccccc2)cc1 Show InChI InChI=1S/C25H27ClN2O3/c1-28(2)16-15-23(18-7-5-4-6-8-18)31-21-12-10-20(11-13-21)27-25(29)19-9-14-24(30-3)22(26)17-19/h4-14,17,23H,15-16H2,1-3H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140070 (CHEMBL3754137) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)S(=O)(=O)N(CCN(C)C)Cc2ccccc2)cc1Cl Show InChI InChI=1S/C25H29ClN4O4S/c1-29(2)15-16-30(18-19-7-5-4-6-8-19)35(32,33)22-12-9-20(10-13-22)27-25(31)28-21-11-14-24(34-3)23(26)17-21/h4-14,17H,15-16,18H2,1-3H3,(H2,27,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013069 (CHEMBL3261686) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3n(C)ccc3c2)cc1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)17-16-26(20-7-5-4-6-8-20)33-24-12-9-22(10-13-24)28-27(32)29-23-11-14-25-21(19-23)15-18-31(25)3/h4-15,18-19,26H,16-17H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50013054 (CHEMBL3261698) Show SMILES COc1cc(NC(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)ccc1Cl Show InChI InChI=1S/C25H28ClN3O3/c1-29(2)16-15-23(18-7-5-4-6-8-18)32-21-12-9-19(10-13-21)27-25(30)28-20-11-14-22(26)24(17-20)31-3/h4-14,17,23H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013070 (CHEMBL3261687) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc3ccn(C)c3c2)cc1)c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-30(2)17-16-26(21-7-5-4-6-8-21)33-24-13-11-22(12-14-24)28-27(32)29-23-10-9-20-15-18-31(3)25(20)19-23/h4-15,18-19,26H,16-17H2,1-3H3,(H2,28,29,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50140065 (CHEMBL3753894) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H21IN2O2S/c1-19(2)12-13-20(14-15-6-4-3-5-7-15)23(21,22)17-10-8-16(18)9-11-17/h3-11H,12-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013068 (CHEMBL3261708) Show SMILES COc1ccc(cc1C(F)(F)F)C(=O)Nc1ccc(OC(CCN(C)C)c2ccccc2)cc1 Show InChI InChI=1S/C26H27F3N2O3/c1-31(2)16-15-23(18-7-5-4-6-8-18)34-21-12-10-20(11-13-21)30-25(32)19-9-14-24(33-3)22(17-19)26(27,28)29/h4-14,17,23H,15-16H2,1-3H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50140064 (CHEMBL3752844) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(NC(=O)Nc2ccc3n(C)ccc3c2)cc1 Show InChI InChI=1S/C27H31N5O3S/c1-30(2)17-18-32(20-21-7-5-4-6-8-21)36(34,35)25-12-9-23(10-13-25)28-27(33)29-24-11-14-26-22(19-24)15-16-31(26)3/h4-16,19H,17-18,20H2,1-3H3,(H2,28,29,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50140063 (CHEMBL3753516) Show SMILES CCn1ccc2cc(NC(=O)Nc3ccc(cc3)S(=O)(=O)N(CCN(C)C)Cc3ccccc3)ccc12 Show InChI InChI=1S/C28H33N5O3S/c1-4-32-17-16-23-20-25(12-15-27(23)32)30-28(34)29-24-10-13-26(14-11-24)37(35,36)33(19-18-31(2)3)21-22-8-6-5-7-9-22/h5-17,20H,4,18-19,21H2,1-3H3,(H2,29,30,34)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50001915 (1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...) Show SMILES Clc1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to 5HT2C (unknown origin)				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013057 (CHEMBL3261700) Show SMILES CN(C)CCC(Oc1cccc(NC(=O)Nc2ccc3ccccc3c2)c1)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c1-31(2)18-17-27(22-10-4-3-5-11-22)33-26-14-8-13-24(20-26)29-28(32)30-25-16-15-21-9-6-7-12-23(21)19-25/h3-16,19-20,27H,17-18H2,1-2H3,(H2,29,30,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50140065 (CHEMBL3753894) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H21IN2O2S/c1-19(2)12-13-20(14-15-6-4-3-5-7-15)23(21,22)17-10-8-16(18)9-11-17/h3-11H,12-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Binding affinity to SERT (unknown origin)				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50140067 (CHEMBL3753681) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C27H33ClN4O2S/c1-29(2)15-20-32(22-23-7-4-3-5-8-23)35(33,34)27-13-11-25(12-14-27)30-16-18-31(19-17-30)26-10-6-9-24(28)21-26/h3-14,21H,15-20,22H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013054 (CHEMBL3261698) Show SMILES COc1cc(NC(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)ccc1Cl Show InChI InChI=1S/C25H28ClN3O3/c1-29(2)16-15-23(18-7-5-4-6-8-18)32-21-12-9-19(10-13-21)27-25(30)28-20-11-14-22(26)24(17-20)31-3/h4-14,17,23H,15-16H2,1-3H3,(H2,27,28,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013066 (CHEMBL3261706) Show SMILES CN(C)CCC(Oc1ccc(NC(=O)c2ccc(C)c(Cl)c2)cc1)c1ccccc1 Show InChI InChI=1S/C25H27ClN2O2/c1-18-9-10-20(17-23(18)26)25(29)27-21-11-13-22(14-12-21)30-24(15-16-28(2)3)19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50140073 (CHEMBL3752059) Show SMILES CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(NC(=O)N2CCN(CC2)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H34ClN5O3S/c1-31(2)15-20-34(22-23-7-4-3-5-8-23)38(36,37)27-13-11-25(12-14-27)30-28(35)33-18-16-32(17-19-33)26-10-6-9-24(29)21-26/h3-14,21H,15-20,22H2,1-2H3,(H,30,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013102 (CHEMBL3261690) Show SMILES CCn1ccc2cc(NC(=O)Nc3ccc(OC(CCN(C)C)c4ccccc4)cc3)ccc12 Show InChI InChI=1S/C28H32N4O2/c1-4-32-19-16-22-20-24(12-15-26(22)32)30-28(33)29-23-10-13-25(14-11-23)34-27(17-18-31(2)3)21-8-6-5-7-9-21/h5-16,19-20,27H,4,17-18H2,1-3H3,(H2,29,30,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry				Bioorg Med Chem Lett 26: 914-20 (2016) Article DOI: 10.1016/j.bmcl.2015.12.071 BindingDB Entry DOI: 10.7270/Q2VX0JC7
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50013102 (CHEMBL3261690) Show SMILES CCn1ccc2cc(NC(=O)Nc3ccc(OC(CCN(C)C)c4ccccc4)cc3)ccc12 Show InChI InChI=1S/C28H32N4O2/c1-4-32-19-16-22-20-24(12-15-26(22)32)30-28(33)29-23-10-13-25(14-11-23)34-27(17-18-31(2)3)21-8-6-5-7-9-21/h5-16,19-20,27H,4,17-18H2,1-3H3,(H2,29,30,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrophotometric analysis				Bioorg Med Chem Lett 24: 2118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.043 BindingDB Entry DOI: 10.7270/Q2G44RV5
					More data for this Ligand-Target Pair

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