Compile Data Set for Download or QSAR

Found 44 hits with Last Name = 'ibrahim' and Initial = 'hm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM5446 (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5446 (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457924 (CHEMBL4208224) Show SMILES Cc1c2cc(Cl)ccc2n2cc(Cc3ccccc3)[nH]c(=O)c12 Show InChI InChI=1S/C19H15ClN2O/c1-12-16-10-14(20)7-8-17(16)22-11-15(21-19(23)18(12)22)9-13-5-3-2-4-6-13/h2-8,10-11H,9H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50457923 (CHEMBL4209588) Show SMILES Cc1c([nH]c2ccc(Cl)cc12)C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C19H19ClN2O2/c1-12-16-10-14(20)7-8-17(16)22-18(12)19(24)21-15(11-23)9-13-5-3-2-4-6-13/h2-8,10,15,22-23H,9,11H2,1H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50457926 (CHEMBL4214496) Show SMILES OCC(Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C18H17ClN2O2/c19-14-6-7-16-13(9-14)10-17(21-16)18(23)20-15(11-22)8-12-4-2-1-3-5-12/h1-7,9-10,15,21-22H,8,11H2,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50457925 (CHEMBL4207316) Show SMILES CCc1c([nH]c2ccc(cc12)C(F)(F)F)C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C21H21F3N2O2/c1-2-16-17-11-14(21(22,23)24)8-9-18(17)26-19(16)20(28)25-15(12-27)10-13-6-4-3-5-7-13/h3-9,11,15,26-27H,2,10,12H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457928 (CHEMBL4213146) Show SMILES CCc1c2cc(ccc2n2cc(Cc3ccccc3)[nH]c(=O)c12)C(F)(F)F Show InChI InChI=1S/C21H17F3N2O/c1-2-16-17-11-14(21(22,23)24)8-9-18(17)26-12-15(25-20(27)19(16)26)10-13-6-4-3-5-7-13/h3-9,11-12H,2,10H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457927 (CHEMBL4208745) Show SMILES Clc1ccc2c(cc3n2cc(Cc2ccccc2)[nH]c3=O)c1 Show InChI InChI=1S/C18H13ClN2O/c19-14-6-7-16-13(9-14)10-17-18(22)20-15(11-21(16)17)8-12-4-2-1-3-5-12/h1-7,9-11H,8H2,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457925 (CHEMBL4207316) Show SMILES CCc1c([nH]c2ccc(cc12)C(F)(F)F)C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C21H21F3N2O2/c1-2-16-17-11-14(21(22,23)24)8-9-18(17)26-19(16)20(28)25-15(12-27)10-13-6-4-3-5-7-13/h3-9,11,15,26-27H,2,10,12H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235313 (CHEMBL4074825) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H20ClN3O2/c1-14-19(23-18-8-7-15(22)13-17(18)20(14)26)21(27)25-11-9-24(10-12-25)16-5-3-2-4-6-16/h2-8,13H,9-12H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235315 (CHEMBL4069774) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCc1nc2ccccc2[nH]1 Show InChI InChI=1S/C19H15ClN4O2/c1-10-17(24-13-7-6-11(20)8-12(13)18(10)25)19(26)21-9-16-22-14-4-2-3-5-15(14)23-16/h2-8H,9H2,1H3,(H,21,26)(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against almonds Beta-glucosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235320 (CHEMBL4087573) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NC1CCCCC1 Show InChI InChI=1S/C17H19ClN2O2/c1-10-15(17(22)19-12-5-3-2-4-6-12)20-14-8-7-11(18)9-13(14)16(10)21/h7-9,12H,2-6H2,1H3,(H,19,22)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against Escherichia coli beta galactosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235317 (CHEMBL4080473) Show SMILES CN(C)c1ccc(CCNC(=O)c2nc3ccc(Cl)cc3c(O)c2C)cc1 Show InChI InChI=1S/C21H22ClN3O2/c1-13-19(24-18-9-6-15(22)12-17(18)20(13)26)21(27)23-11-10-14-4-7-16(8-5-14)25(2)3/h4-9,12H,10-11H2,1-3H3,(H,23,27)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235314 (CHEMBL4103022) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCCc1ccc(cc1)N1CCCC1 Show InChI InChI=1S/C23H24ClN3O2/c1-15-21(26-20-9-6-17(24)14-19(20)22(15)28)23(29)25-11-10-16-4-7-18(8-5-16)27-12-2-3-13-27/h4-9,14H,2-3,10-13H2,1H3,(H,25,29)(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50457924 (CHEMBL4208224) Show SMILES Cc1c2cc(Cl)ccc2n2cc(Cc3ccccc3)[nH]c(=O)c12 Show InChI InChI=1S/C19H15ClN2O/c1-12-16-10-14(20)7-8-17(16)22-11-15(21-19(23)18(12)22)9-13-5-3-2-4-6-13/h2-8,10-11H,9H2,1H3,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235309 (CHEMBL4096972) Show SMILES CN(C(=O)c1nc2ccc(Cl)cc2c(O)c1C)c1ccccc1 Show InChI InChI=1S/C18H15ClN2O2/c1-11-16(18(23)21(2)13-6-4-3-5-7-13)20-15-9-8-12(19)10-14(15)17(11)22/h3-10H,1-2H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235311 (CHEMBL4095272) Show SMILES CCOC(=O)C(Cc1ccccc1)NC(=O)c1nc2ccc(Cl)cc2c(O)c1C Show InChI InChI=1S/C22H21ClN2O4/c1-3-29-22(28)18(11-14-7-5-4-6-8-14)25-21(27)19-13(2)20(26)16-12-15(23)9-10-17(16)24-19/h4-10,12,18H,3,11H2,1-2H3,(H,24,26)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235308 (CHEMBL4089272) Show SMILES CC1CCCN1c1ccc(CCNC(=O)c2nc3ccc(Cl)cc3c(O)c2C)cc1 Show InChI InChI=1S/C24H26ClN3O2/c1-15-4-3-13-28(15)19-8-5-17(6-9-19)11-12-26-24(30)22-16(2)23(29)20-14-18(25)7-10-21(20)27-22/h5-10,14-15H,3-4,11-13H2,1-2H3,(H,26,30)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235310 (CHEMBL4099420) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H26ClN3O2/c1-16-22(27-21-10-7-18(25)15-20(21)23(16)29)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15H,2-4,11-14H2,1H3,(H,26,30)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50457927 (CHEMBL4208745) Show SMILES Clc1ccc2c(cc3n2cc(Cc2ccccc2)[nH]c3=O)c1 Show InChI InChI=1S/C18H13ClN2O/c19-14-6-7-16-13(9-14)10-17-18(22)20-15(11-21(16)17)8-12-4-2-1-3-5-12/h1-7,9-11H,8H2,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235307 (CHEMBL4061105) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCCc1ccccc1 Show InChI InChI=1S/C19H17ClN2O2/c1-12-17(19(24)21-10-9-13-5-3-2-4-6-13)22-16-8-7-14(20)11-15(16)18(12)23/h2-8,11H,9-10H2,1H3,(H,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235321 (CHEMBL4066211) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C20H19ClN2O3/c1-12-18(23-17-8-7-14(21)10-16(17)19(12)25)20(26)22-15(11-24)9-13-5-3-2-4-6-13/h2-8,10,15,24H,9,11H2,1H3,(H,22,26)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against Escherichia coli beta galactosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235319 (CHEMBL4066899) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCNCC1 Show InChI InChI=1S/C15H16ClN3O2/c1-9-13(15(21)19-6-4-17-5-7-19)18-12-3-2-10(16)8-11(12)14(9)20/h2-3,8,17H,4-7H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235316 (CHEMBL4104705) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCCCC1 Show InChI InChI=1S/C16H17ClN2O2/c1-10-14(16(21)19-7-3-2-4-8-19)18-13-6-5-11(17)9-12(13)15(10)20/h5-6,9H,2-4,7-8H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50235318 (CHEMBL4076205) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NC1CCCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H24ClN3O2/c1-15-21(26-20-10-9-17(24)12-19(20)22(15)28)23(29)25-18-8-5-11-27(14-18)13-16-6-3-2-4-7-16/h2-4,6-7,9-10,12,18H,5,8,11,13-14H2,1H3,(H,25,29)(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457923 (CHEMBL4209588) Show SMILES Cc1c([nH]c2ccc(Cl)cc12)C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C19H19ClN2O2/c1-12-16-10-14(20)7-8-17(16)22-18(12)19(24)21-15(11-23)9-13-5-3-2-4-6-13/h2-8,10,15,22-23H,9,11H2,1H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50457928 (CHEMBL4213146) Show SMILES CCc1c2cc(ccc2n2cc(Cc3ccccc3)[nH]c(=O)c12)C(F)(F)F Show InChI InChI=1S/C21H17F3N2O/c1-2-16-17-11-14(21(22,23)24)8-9-18(17)26-12-15(25-20(27)19(16)26)10-13-6-4-3-5-7-13/h3-9,11-12H,2,10H2,1H3,(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Mus musculus)	BDBM50457926 (CHEMBL4214496) Show SMILES OCC(Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C18H17ClN2O2/c19-14-6-7-16-13(9-14)10-17(21-16)18(23)20-15(11-22)8-12-4-2-1-3-5-12/h1-7,9-10,15,21-22H,8,11H2,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aljouf University Curated by ChEMBL					Assay Description Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...				Eur J Med Chem 146: 260-273 (2018) Article DOI: 10.1016/j.ejmech.2018.01.042 BindingDB Entry DOI: 10.7270/Q25X2CKD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235314 (CHEMBL4103022) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCCc1ccc(cc1)N1CCCC1 Show InChI InChI=1S/C23H24ClN3O2/c1-15-21(26-20-9-6-17(24)14-19(20)22(15)28)23(29)25-11-10-16-4-7-18(8-5-16)27-12-2-3-13-27/h4-9,14H,2-3,10-13H2,1H3,(H,25,29)(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235320 (CHEMBL4087573) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NC1CCCCC1 Show InChI InChI=1S/C17H19ClN2O2/c1-10-15(17(22)19-12-5-3-2-4-6-12)20-14-8-7-11(18)9-13(14)16(10)21/h7-9,12H,2-6H2,1H3,(H,19,22)(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235315 (CHEMBL4069774) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCc1nc2ccccc2[nH]1 Show InChI InChI=1S/C19H15ClN4O2/c1-10-17(24-13-7-6-11(20)8-12(13)18(10)25)19(26)21-9-16-22-14-4-2-3-5-15(14)23-16/h2-8H,9H2,1H3,(H,21,26)(H,22,23)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235317 (CHEMBL4080473) Show SMILES CN(C)c1ccc(CCNC(=O)c2nc3ccc(Cl)cc3c(O)c2C)cc1 Show InChI InChI=1S/C21H22ClN3O2/c1-13-19(24-18-9-6-15(22)12-17(18)20(13)26)21(27)23-11-10-14-4-7-16(8-5-14)25(2)3/h4-9,12H,10-11H2,1-3H3,(H,23,27)(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235309 (CHEMBL4096972) Show SMILES CN(C(=O)c1nc2ccc(Cl)cc2c(O)c1C)c1ccccc1 Show InChI InChI=1S/C18H15ClN2O2/c1-11-16(18(23)21(2)13-6-4-3-5-7-13)20-15-9-8-12(19)10-14(15)17(11)22/h3-10H,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against almonds Beta-glucosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235313 (CHEMBL4074825) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H20ClN3O2/c1-14-19(23-18-8-7-15(22)13-17(18)20(14)26)21(27)25-11-9-24(10-12-25)16-5-3-2-4-6-16/h2-8,13H,9-12H2,1H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235311 (CHEMBL4095272) Show SMILES CCOC(=O)C(Cc1ccccc1)NC(=O)c1nc2ccc(Cl)cc2c(O)c1C Show InChI InChI=1S/C22H21ClN2O4/c1-3-29-22(28)18(11-14-7-5-4-6-8-14)25-21(27)19-13(2)20(26)16-12-15(23)9-10-17(16)24-19/h4-10,12,18H,3,11H2,1-2H3,(H,24,26)(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235308 (CHEMBL4089272) Show SMILES CC1CCCN1c1ccc(CCNC(=O)c2nc3ccc(Cl)cc3c(O)c2C)cc1 Show InChI InChI=1S/C24H26ClN3O2/c1-15-4-3-13-28(15)19-8-5-17(6-9-19)11-12-26-24(30)22-16(2)23(29)20-14-18(25)7-10-21(20)27-22/h5-10,14-15H,3-4,11-13H2,1-2H3,(H,26,30)(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against bovine liver beta galactosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235310 (CHEMBL4099420) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H26ClN3O2/c1-16-22(27-21-10-7-18(25)15-20(21)23(16)29)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15H,2-4,11-14H2,1H3,(H,26,30)(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235319 (CHEMBL4066899) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCNCC1 Show InChI InChI=1S/C15H16ClN3O2/c1-9-13(15(21)19-6-4-17-5-7-19)18-12-3-2-10(16)8-11(12)14(9)20/h2-3,8,17H,4-7H2,1H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against almonds Beta-glucosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235307 (CHEMBL4061105) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NCCc1ccccc1 Show InChI InChI=1S/C19H17ClN2O2/c1-12-17(19(24)21-10-9-13-5-3-2-4-6-13)22-16-8-7-14(20)11-15(16)18(12)23/h2-8,11H,9-10H2,1H3,(H,21,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235321 (CHEMBL4066211) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C20H19ClN2O3/c1-12-18(23-17-8-7-14(21)10-16(17)19(12)25)20(26)22-15(11-24)9-13-5-3-2-4-6-13/h2-8,10,15,24H,9,11H2,1H3,(H,22,26)(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235316 (CHEMBL4104705) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCCCC1 Show InChI InChI=1S/C16H17ClN2O2/c1-10-14(16(21)19-7-3-2-4-8-19)18-13-6-5-11(17)9-12(13)15(10)20/h5-6,9H,2-4,7-8H2,1H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibitory activity was determined against Escherichia coli Alpha-galactosidase				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50235318 (CHEMBL4076205) Show SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)NC1CCCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H24ClN3O2/c1-15-21(26-20-10-9-17(24)12-19(20)22(15)28)23(29)25-18-8-5-11-27(14-18)13-16-6-3-2-4-7-16/h2-4,6-7,9-10,12,18H,5,8,11,13-14H2,1H3,(H,25,29)(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...				Eur J Med Chem 127: 972-985 (2017) Article DOI: 10.1016/j.ejmech.2016.11.006 BindingDB Entry DOI: 10.7270/Q2NC63G3
					More data for this Ligand-Target Pair