Compile Data Set for Download or QSAR

Found 88 hits with Last Name = 'jolicoeur' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075655 (3-(4-Methanesulfonyl-phenyl)-2-(3,4,5-trichloro-ph...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)c(Cl)c(Cl)c1 |t:11| Show InChI InChI=1S/C18H13Cl3O3S/c1-25(23,24)12-4-2-10(3-5-12)13-6-7-16(22)17(13)11-8-14(19)18(21)15(20)9-11/h2-5,8-9H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075667 (3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclo...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C#Cc2ccccc2)C(=O)CC1 |c:11| Show InChI InChI=1S/C20H16O3S/c1-24(22,23)17-10-8-16(9-11-17)18-13-14-20(21)19(18)12-7-15-5-3-2-4-6-15/h2-6,8-11H,13-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075658 (2-(3-Chloro-4-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)c(Cl)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-16(20)15(19)10-12/h2-6,8,10H,7,9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075662 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1 |t:11| Show InChI InChI=1S/C18H16O3S/c1-22(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075675 (3-(4-Methanesulfonyl-phenyl)-2-phenoxy-cyclopent-2...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(Oc2ccccc2)C(=O)CC1 |c:11| Show InChI InChI=1S/C18H16O4S/c1-23(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)22-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075668 (2-(3H-1lambda*4*-Benzo[b]thiophen-2-yl)-3-(4-metha...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc2ccccc2s1 |t:11| Show InChI InChI=1S/C20H16O3S2/c1-25(22,23)15-8-6-13(7-9-15)16-10-11-17(21)20(16)19-12-14-4-2-3-5-18(14)24-19/h2-9,12H,10-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075656 (2-(3,5-Dichloro-phenyl)-3-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)cc(Cl)c1 |t:11| Show InChI InChI=1S/C18H14Cl2O3S/c1-24(22,23)15-4-2-11(3-5-15)16-6-7-17(21)18(16)12-8-13(19)10-14(20)9-12/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075669 (2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cccc(F)c1 |t:11| Show InChI InChI=1S/C18H15FO3S/c1-23(21,22)15-7-5-12(6-8-15)16-9-10-17(20)18(16)13-3-2-4-14(19)11-13/h2-8,11H,9-10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075657 (2-(3,4-Difluoro-phenyl)-3-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)c(F)c1 |t:11| Show InChI InChI=1S/C18H14F2O3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-15(19)16(20)10-12/h2-6,8,10H,7,9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075673 (2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(Cl)c(F)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-15(19)16(20)10-12/h2-6,8,10H,7,9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075664 (2-(3,5-Difluoro-phenyl)-3-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(F)cc(F)c1 |t:11| Show InChI InChI=1S/C18H14F2O3S/c1-24(22,23)15-4-2-11(3-5-15)16-6-7-17(21)18(16)12-8-13(19)10-14(20)9-12/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075670 (2-(3,5-Difluoro-phenoxy)-3-(4-methanesulfonyl-phen...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(Oc2cc(F)cc(F)c2)C(=O)CC1 |c:11| Show InChI InChI=1S/C18H14F2O4S/c1-25(22,23)15-4-2-11(3-5-15)16-6-7-17(21)18(16)24-14-9-12(19)8-13(20)10-14/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075653 (2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C18H15FO3S/c1-23(21,22)15-8-4-12(5-9-15)16-10-11-17(20)18(16)13-2-6-14(19)7-3-13/h2-9H,10-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22369 (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075672 (3-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-pyridin-...) Show SMILES COc1ccncc1C1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O |t:9| Show InChI InChI=1S/C18H17NO4S/c1-23-17-9-10-19-11-15(17)18-14(7-8-16(18)20)12-3-5-13(6-4-12)24(2,21)22/h3-6,9-11H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075653 (2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C18H15FO3S/c1-23(21,22)15-8-4-12(5-9-15)16-10-11-17(20)18(16)13-2-6-14(19)7-3-13/h2-9H,10-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075668 (2-(3H-1lambda*4*-Benzo[b]thiophen-2-yl)-3-(4-metha...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc2ccccc2s1 |t:11| Show InChI InChI=1S/C20H16O3S2/c1-25(22,23)15-8-6-13(7-9-15)16-10-11-17(21)20(16)19-12-14-4-2-3-5-18(14)24-19/h2-9,12H,10-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075652 (2-(5-Chloro-pyridin-3-yl)-3-(4-methanesulfonyl-phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cncc(Cl)c1 |t:11| Show InChI InChI=1S/C17H14ClNO3S/c1-23(21,22)14-4-2-11(3-5-14)15-6-7-16(20)17(15)12-8-13(18)10-19-9-12/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075658 (2-(3-Chloro-4-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)c(Cl)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-16(20)15(19)10-12/h2-6,8,10H,7,9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075672 (3-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-pyridin-...) Show SMILES COc1ccncc1C1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O |t:9| Show InChI InChI=1S/C18H17NO4S/c1-23-17-9-10-19-11-15(17)18-14(7-8-16(18)20)12-3-5-13(6-4-12)24(2,21)22/h3-6,9-11H,7-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075668 (2-(3H-1lambda*4*-Benzo[b]thiophen-2-yl)-3-(4-metha...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc2ccccc2s1 |t:11| Show InChI InChI=1S/C20H16O3S2/c1-25(22,23)15-8-6-13(7-9-15)16-10-11-17(21)20(16)19-12-14-4-2-3-5-18(14)24-19/h2-9,12H,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075673 (2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(Cl)c(F)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-15(19)16(20)10-12/h2-6,8,10H,7,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075672 (3-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-pyridin-...) Show SMILES COc1ccncc1C1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O |t:9| Show InChI InChI=1S/C18H17NO4S/c1-23-17-9-10-19-11-15(17)18-14(7-8-16(18)20)12-3-5-13(6-4-12)24(2,21)22/h3-6,9-11H,7-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075673 (2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(Cl)c(F)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-15(19)16(20)10-12/h2-6,8,10H,7,9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075659 (2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-p...) Show SMILES CC(C)(C)C#CC1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O |t:6| Show InChI InChI=1S/C18H20O3S/c1-18(2,3)12-11-16-15(9-10-17(16)19)13-5-7-14(8-6-13)22(4,20)21/h5-8H,9-10H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075660 (3-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-cyclop...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cccnc1 |t:11| Show InChI InChI=1S/C17H15NO3S/c1-22(20,21)14-6-4-12(5-7-14)15-8-9-16(19)17(15)13-3-2-10-18-11-13/h2-7,10-11H,8-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075674 (2-[(E)-2-(4-Fluoro-phenyl)-vinyl]-3-(4-methanesulf...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C=Cc2ccc(F)cc2)C(=O)CC1 |w:13.14,c:11| Show InChI InChI=1S/C20H17FO3S/c1-25(23,24)17-9-5-15(6-10-17)18-12-13-20(22)19(18)11-4-14-2-7-16(21)8-3-14/h2-11H,12-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075662 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1 |t:11| Show InChI InChI=1S/C18H16O3S/c1-22(20,21)15-9-7-13(8-10-15)16-11-12-17(19)18(16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075663 (2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)ccn1 |t:11| Show InChI InChI=1S/C17H14ClNO3S/c1-23(21,22)13-4-2-11(3-5-13)14-6-7-16(20)17(14)15-10-12(18)8-9-19-15/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075657 (2-(3,4-Difluoro-phenyl)-3-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)c(F)c1 |t:11| Show InChI InChI=1S/C18H14F2O3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-15(19)16(20)10-12/h2-6,8,10H,7,9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075656 (2-(3,5-Dichloro-phenyl)-3-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)cc(Cl)c1 |t:11| Show InChI InChI=1S/C18H14Cl2O3S/c1-24(22,23)15-4-2-11(3-5-15)16-6-7-17(21)18(16)12-8-13(19)10-14(20)9-12/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075658 (2-(3-Chloro-4-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)c(Cl)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-16(20)15(19)10-12/h2-6,8,10H,7,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075654 (2-(5-Bromo-pyridin-3-yl)-3-(4-methanesulfonyl-phen...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cncc(Br)c1 |t:11| Show InChI InChI=1S/C17H14BrNO3S/c1-23(21,22)14-4-2-11(3-5-14)15-6-7-16(20)17(15)12-8-13(18)10-19-9-12/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075669 (2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cccc(F)c1 |t:11| Show InChI InChI=1S/C18H15FO3S/c1-23(21,22)15-7-5-12(6-8-15)16-9-10-17(20)18(16)13-3-2-4-14(19)11-13/h2-8,11H,9-10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075665 (3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3...) Show SMILES Cc1ccncc1C1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O |t:8| Show InChI InChI=1S/C18H17NO3S/c1-12-9-10-19-11-16(12)18-15(7-8-17(18)20)13-3-5-14(6-4-13)23(2,21)22/h3-6,9-11H,7-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075665 (3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3...) Show SMILES Cc1ccncc1C1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O |t:8| Show InChI InChI=1S/C18H17NO3S/c1-12-9-10-19-11-16(12)18-15(7-8-17(18)20)13-3-5-14(6-4-13)23(2,21)22/h3-6,9-11H,7-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075671 (2-(4-Bromo-pyridin-2-yl)-3-(4-methanesulfonyl-phen...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Br)ccn1 |t:11| Show InChI InChI=1S/C17H14BrNO3S/c1-23(21,22)13-4-2-11(3-5-13)14-6-7-16(20)17(14)15-10-12(18)8-9-19-15/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22369 (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075653 (2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C18H15FO3S/c1-23(21,22)15-8-4-12(5-9-15)16-10-11-17(20)18(16)13-2-6-14(19)7-3-13/h2-9H,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075674 (2-[(E)-2-(4-Fluoro-phenyl)-vinyl]-3-(4-methanesulf...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C=Cc2ccc(F)cc2)C(=O)CC1 |w:13.14,c:11| Show InChI InChI=1S/C20H17FO3S/c1-25(23,24)17-9-5-15(6-10-17)18-12-13-20(22)19(18)11-4-14-2-7-16(21)8-3-14/h2-11H,12-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075663 (2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)ccn1 |t:11| Show InChI InChI=1S/C17H14ClNO3S/c1-23(21,22)13-4-2-11(3-5-13)14-6-7-16(20)17(14)15-10-12(18)8-9-19-15/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075664 (2-(3,5-Difluoro-phenyl)-3-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(F)cc(F)c1 |t:11| Show InChI InChI=1S/C18H14F2O3S/c1-24(22,23)15-4-2-11(3-5-15)16-6-7-17(21)18(16)12-8-13(19)10-14(20)9-12/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075671 (2-(4-Bromo-pyridin-2-yl)-3-(4-methanesulfonyl-phen...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Br)ccn1 |t:11| Show InChI InChI=1S/C17H14BrNO3S/c1-23(21,22)13-4-2-11(3-5-13)14-6-7-16(20)17(14)15-10-12(18)8-9-19-15/h2-5,8-10H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075667 (3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclo...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C#Cc2ccccc2)C(=O)CC1 |c:11| Show InChI InChI=1S/C20H16O3S/c1-24(22,23)17-10-8-16(9-11-17)18-13-14-20(21)19(18)12-7-15-5-3-2-4-6-15/h2-6,8-11H,13-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075660 (3-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-cyclop...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cccnc1 |t:11| Show InChI InChI=1S/C17H15NO3S/c1-22(20,21)14-6-4-12(5-7-14)15-8-9-16(19)17(15)13-3-2-10-18-11-13/h2-7,10-11H,8-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075673 (2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(Cl)c(F)c1 |t:11| Show InChI InChI=1S/C18H14ClFO3S/c1-24(22,23)13-5-2-11(3-6-13)14-7-9-17(21)18(14)12-4-8-15(19)16(20)10-12/h2-6,8,10H,7,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50075667 (3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclo...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C#Cc2ccccc2)C(=O)CC1 |c:11| Show InChI InChI=1S/C20H16O3S/c1-24(22,23)17-10-8-16(9-11-17)18-13-14-20(21)19(18)12-7-15-5-3-2-4-6-15/h2-6,8-11H,13-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50075655 (3-(4-Methanesulfonyl-phenyl)-2-(3,4,5-trichloro-ph...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)c(Cl)c(Cl)c1 |t:11| Show InChI InChI=1S/C18H13Cl3O3S/c1-25(23,24)12-4-2-10(3-5-12)13-6-7-16(22)17(13)11-8-14(19)18(21)15(20)9-11/h2-5,8-9H,6-7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.				J Med Chem 42: 1274-81 (1999) Article DOI: 10.1021/jm980642l BindingDB Entry DOI: 10.7270/Q21V5FNB
					More data for this Ligand-Target Pair

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