Found 14 hits with Last Name = 'jones' and Initial = 'dm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288303
((R)-3-((S)-2-Amino-3-methyl-pentanoyl)-thiazolidin...)Show InChI InChI=1S/C10H17N3OS/c1-3-7(2)9(12)10(14)13-6-15-5-8(13)4-11/h7-9H,3,5-6,12H2,1-2H3/t7?,8-,9+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288308
((R)-3-(2-Amino-2-cyclopentyl-acetyl)-thiazolidine-...)Show InChI InChI=1S/C11H17N3OS/c12-5-9-6-16-7-14(9)11(15)10(13)8-3-1-2-4-8/h8-10H,1-4,6-7,13H2/t9-,10?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288307
((R)-3-(2-Amino-2-cyclohexyl-acetyl)-thiazolidine-4...)Show InChI InChI=1S/C12H19N3OS/c13-6-10-7-17-8-15(10)12(16)11(14)9-4-2-1-3-5-9/h9-11H,1-5,7-8,14H2/t10-,11?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11644
((2S)-1-[(2S)-2-amino-2-cyclopentylacetyl]pyrrolidi...)Show InChI InChI=1S/C12H19N3O/c13-8-10-6-3-7-15(10)12(16)11(14)9-4-1-2-5-9/h9-11H,1-7,14H2/t10-,11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288298
((S)-3-((S)-2-Amino-3-methyl-pentanoyl)-thiazolidin...)Show InChI InChI=1S/C10H17N3OS/c1-3-7(2)9(12)10(14)13-4-5-15-8(13)6-11/h7-9H,3-5,12H2,1-2H3/t7?,8-,9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288299
((S)-1-((S)-2-Amino-3-methyl-pentanoyl)-pyrrolidine...)Show InChI InChI=1S/C11H19N3O/c1-3-8(2)10(13)11(15)14-6-4-5-9(14)7-12/h8-10H,3-6,13H2,1-2H3/t8?,9-,10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288297
(CHEMBL92175 | [5-Amino-1-((R)-4-cyano-thiazolidine...)Show SMILES NCCCCC(NC(=O)OCc1ccccc1)C(=O)N1CSC[C@H]1C#N Show InChI InChI=1S/C18H24N4O3S/c19-9-5-4-8-16(17(23)22-13-26-12-15(22)10-20)21-18(24)25-11-14-6-2-1-3-7-14/h1-3,6-7,15-16H,4-5,8-9,11-13,19H2,(H,21,24)/t15-,16?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288301
((R)-3-((S)-2-Amino-3-methyl-pentanoyl)-1,1-dioxo-t...)Show SMILES CCC(C)[C@H](N)C(=O)N1CS(=O)(=O)C[C@H]1C#N |r| Show InChI InChI=1S/C10H17N3O3S/c1-3-7(2)9(12)10(14)13-6-17(15,16)5-8(13)4-11/h7-9H,3,5-6,12H2,1-2H3/t7?,8-,9+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50450427
(CHEMBL2115247)Show SMILES CC[C@H](C)[C@H](N)C(=O)N1C[S+]([O-])C[C@H]1C#N |r| Show InChI InChI=1S/C10H17N3O2S/c1-3-7(2)9(12)10(14)13-6-16(15)5-8(13)4-11/h7-9H,3,5-6,12H2,1-2H3/t7-,8+,9-,16?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50450427
(CHEMBL2115247)Show SMILES CC[C@H](C)[C@H](N)C(=O)N1C[S+]([O-])C[C@H]1C#N |r| Show InChI InChI=1S/C10H17N3O2S/c1-3-7(2)9(12)10(14)13-6-16(15)5-8(13)4-11/h7-9H,3,5-6,12H2,1-2H3/t7-,8+,9-,16?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288306
((S)-1-((S)-2-Amino-3-methyl-pentanoyl)-piperidine-...)Show InChI InChI=1S/C12H21N3O/c1-3-9(2)11(14)12(16)15-7-5-4-6-10(15)8-13/h9-11H,3-7,14H2,1-2H3/t9?,10-,11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288300
((R)-3-((S)-2-Amino-3-methyl-pentanoyl)-oxazolidine...)Show InChI InChI=1S/C10H17N3O2/c1-3-7(2)9(12)10(14)13-6-15-5-8(13)4-11/h7-9H,3,5-6,12H2,1-2H3/t7?,8-,9+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288304
((S)-1-((S)-2-Amino-3-methyl-pentanoyl)-2-methyl-py...)Show InChI InChI=1S/C12H21N3O/c1-4-9(2)10(14)11(16)15-7-5-6-12(15,3)8-13/h9-10H,4-7,14H2,1-3H3/t9?,10-,12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50288305
(3-((S)-2-Amino-3-methyl-pentanoyl)-[1,3]thiazinane...)Show InChI InChI=1S/C11H19N3OS/c1-3-8(2)10(13)11(15)14-7-16-5-4-9(14)6-12/h8-10H,3-5,7,13H2,1-2H3/t8?,9?,10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human Dipeptidyl peptidase IV |
Bioorg Med Chem Lett 6: 2745-2748 (1996)
Article DOI: 10.1016/S0960-894X(96)00491-X BindingDB Entry DOI: 10.7270/Q2MP537C |
More data for this Ligand-Target Pair | |