Found 155 hits with Last Name = 'kalidindi' and Initial = 'n' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM198694
(US9221796, 23b)Show SMILES Cc1ccc(CN2CC[C@@H](N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H28N2O2/c1-17-2-4-18(5-3-17)16-25-15-12-22(23(25)27)24-13-10-20(11-14-24)19-6-8-21(26)9-7-19/h2-9,20,22,26H,10-16H2,1H3/t22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM198665
(US9221796, 2b)Show SMILES Oc1ccc(cc1)C1CCN(CC1)[C@@H]1CCN(Cc2ccc(F)cc2)C1=O |r| Show InChI InChI=1S/C22H25FN2O2/c23-19-5-1-16(2-6-19)15-25-14-11-21(22(25)27)24-12-9-18(10-13-24)17-3-7-20(26)8-4-17/h1-8,18,21,26H,9-15H2/t21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM198728
(US9221796, 46, P-4)Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21+,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM198726
(US9221796, 46, P-2)Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@@H]([C@@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21+,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50330324
(CHEMBL4170867)Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21-,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Homo sapiens (Human)) | BDBM198728
(US9221796, 46, P-4)Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21+,22+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity to GluN2B receptor in human cortex |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50330409
(CHEMBL4168402)Show SMILES Cc1ccc(CN2CC[C@@H](N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1 |r| Show InChI InChI=1S/C23H26F2N2O2/c1-16-2-4-17(5-3-16)14-26-13-11-21(22(26)29)27-12-10-20(23(24,25)15-27)18-6-8-19(28)9-7-18/h2-9,20-21,28H,10-15H2,1H3/t20?,21-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50330410
(CHEMBL4161899)Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21-,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM198735
(US9221796, 48, P-3)Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(F)cc2)C1=O |r| Show InChI InChI=1S/C22H24F2N2O2/c23-17-5-1-15(2-6-17)13-26-12-10-21(22(26)28)25-11-9-19(20(24)14-25)16-3-7-18(27)8-4-16/h1-8,19-21,27H,9-14H2/t19-,20+,21+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Homo sapiens (Human)) | BDBM198665
(US9221796, 2b)Show SMILES Oc1ccc(cc1)C1CCN(CC1)[C@@H]1CCN(Cc2ccc(F)cc2)C1=O |r| Show InChI InChI=1S/C22H25FN2O2/c23-19-5-1-16(2-6-19)15-25-14-11-21(22(25)27)24-12-9-18(10-13-24)17-3-7-20(26)8-4-17/h1-8,18,21,26H,9-15H2/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity to GluN2B receptor in human cortex |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581785
(CHEMBL5081052)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1nccs1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541746
(US11267811, Example A78)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Br)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541728
(US11267811, Example A58)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581762
(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)Show SMILES OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM50581778
(CHEMBL5090468)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cnc(OC)nc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541639
(US11267811, Example 250)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581782
(CHEMBL5093414)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cccc(n1)C(=O)OC)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581775
(CHEMBL5087430)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cnccn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581774
(CHEMBL5091613)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cncnc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM50581772
(CHEMBL5076024)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ccccn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581779
(CHEMBL5092373)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ncc(F)cn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50594519
(CHEMBL5206873)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM50581783
(CHEMBL5087660)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1nccc(N)n1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541721
(US11267811, Example A51)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(Cl)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541676
(US11267811, Example A6)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581787
(CHEMBL5076553)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)C1CCOCC1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581777
(CHEMBL5093408)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ncc(OC)cn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581773
(CHEMBL5081775)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ncccn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Homo sapiens (Human)) | BDBM198728
(US9221796, 46, P-4)Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21+,22+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human GluN2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced chann... |
ACS Med Chem Lett 9: 472-477 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00080
BindingDB Entry DOI: 10.7270/Q2PR7ZJT |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581776
(CHEMBL5075458)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ccc(OC)nc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581784
(CHEMBL5074202)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1nccc(NC(C)=O)n1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541474
(US11267811, Example 68)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)ccc1Br |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581771
(CHEMBL5081635)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cccc(NC(C)=O)c1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541468
(US11267811, Example 62)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)ccc1C |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581770
(CHEMBL5086496)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cccc(N)c1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541726
(US11267811, Example A56)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c3ccccc3c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541698
(US11267811, Example A28)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Br)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581789
(CHEMBL5080440)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cncnc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(Cl)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541697
(US11267811, Example A27)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Br)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581781
(CHEMBL5093807)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ccnc(Cl)c1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581769
(CHEMBL5093100)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cccc(O)c1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541464
(US11267811, Example 58)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)ccc1Cl |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581764
(CHEMBL5091374)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ccccc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581780
(CHEMBL5069594)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cnc(nc1)C(F)(F)F)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Mus musculus) | BDBM541746
(US11267811, Example A78)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Br)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581786
(CHEMBL5080579)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)C1CCCCC1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541467
(US11267811, Example 61)Show SMILES COc1ccc(Cl)cc1-n1nc(C)nc1[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581774
(CHEMBL5091613)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cncnc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Gal3-induced chemotaxis using human monocyte incubated for 4 hrs by calcein-AM dye based assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM541466
(US11267811, Example 60)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)ccc1F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Mus musculus) | BDBM50581762
(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)Show SMILES OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to mouse Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
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