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Compile Data Set for Download or QSAR

Found 3 hits with Last Name = 'keffer' and Initial = 'jl'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...


Bioorg Med Chem 21: 5673-8 (2013)


Article DOI: 10.1016/j.bmc.2013.07.033
BindingDB Entry DOI: 10.7270/Q2057HC4
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50439495
PNG
(CHEMBL2418095)
Show SMILES Oc1cc(O)c2Oc3cc(C\C=C(Cl)/Cc4cc(O)c(Oc5cc(C\C=C(Cl)/Cc2c1)c(O)cc5Cl)c(O)c4)c(O)cc3Cl |t:11,25|
Show InChI InChI=1S/C32H24Cl4O8/c33-19-3-1-16-10-29(22(35)13-24(16)38)43-31-18(9-21(37)12-28(31)42)8-20(34)4-2-17-11-30(23(36)14-25(17)39)44-32-26(40)6-15(5-19)7-27(32)41/h3-4,6-7,9-14,37-42H,1-2,5,8H2/b19-3+,20-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.70E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...


Bioorg Med Chem 21: 5673-8 (2013)


Article DOI: 10.1016/j.bmc.2013.07.033
BindingDB Entry DOI: 10.7270/Q2057HC4
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Bacillus subtilis)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphom...


Bioorg Med Chem 21: 5673-8 (2013)


Article DOI: 10.1016/j.bmc.2013.07.033
BindingDB Entry DOI: 10.7270/Q2057HC4
More data for this
Ligand-Target Pair