Compile Data Set for Download or QSAR

Found 278 hits with Last Name = 'keim' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM82423 (CAS_132947 | NSC_132947 | TRIPITRAMINE) Show SMILES CN(CCCCCCCCN(C)CCCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C64H77N13O6/c1-72(41-20-8-5-17-35-65-44-56(78)75-53-32-14-11-26-47(53)62(81)69-50-29-23-36-66-59(50)75)39-18-6-3-4-7-19-40-73(2)42-21-9-10-22-43-74(45-57(79)76-54-33-15-12-27-48(54)63(82)70-51-30-24-37-67-60(51)76)46-58(80)77-55-34-16-13-28-49(55)64(83)71-52-31-25-38-68-61(52)77/h11-16,23-34,36-38,65H,3-10,17-22,35,39-46H2,1-2H3,(H,69,81)(H,70,82)(H,71,83)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	0.269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M2 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297307 (CHEMBL564226 | R-dimethindene) Show SMILES C[C@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |r,c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.437	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM81452 (CAS_91533 | Dimethindene | NSC_91533) Show SMILES CC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	0.692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50474506 (CHEMBL167223) Show SMILES CC(C1=C(CCN(C)C)Cc2cc(Cl)ccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H23ClN2/c1-14(19-6-4-5-10-22-19)20-15(9-11-23(2)3)12-16-13-17(21)7-8-18(16)20/h4-8,10,13-14H,9,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM82423 (CAS_132947 | NSC_132947 | TRIPITRAMINE) Show SMILES CN(CCCCCCCCN(C)CCCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C64H77N13O6/c1-72(41-20-8-5-17-35-65-44-56(78)75-53-32-14-11-26-47(53)62(81)69-50-29-23-36-66-59(50)75)39-18-6-3-4-7-19-40-73(2)42-21-9-10-22-43-74(45-57(79)76-54-33-15-12-27-48(54)63(82)70-51-30-24-37-67-60(51)76)46-58(80)77-55-34-16-13-28-49(55)64(83)71-52-31-25-38-68-61(52)77/h11-16,23-34,36-38,65H,3-10,17-22,35,39-46H2,1-2H3,(H,69,81)(H,70,82)(H,71,83)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M1 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM81901 (AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356) Show SMILES CCCN(CCC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M2 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM82423 (CAS_132947 | NSC_132947 | TRIPITRAMINE) Show SMILES CN(CCCCCCCCN(C)CCCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C64H77N13O6/c1-72(41-20-8-5-17-35-65-44-56(78)75-53-32-14-11-26-47(53)62(81)69-50-29-23-36-66-59(50)75)39-18-6-3-4-7-19-40-73(2)42-21-9-10-22-43-74(45-57(79)76-54-33-15-12-27-48(54)63(82)70-51-30-24-37-67-60(51)76)46-58(80)77-55-34-16-13-28-49(55)64(83)71-52-31-25-38-68-61(52)77/h11-16,23-34,36-38,65H,3-10,17-22,35,39-46H2,1-2H3,(H,69,81)(H,70,82)(H,71,83)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M4 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50474496 (CHEMBL172233) Show SMILES CC(C1=C(CCN(C)CCF)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C21H25FN2/c1-16(20-9-5-6-12-23-20)21-18(10-13-24(2)14-11-22)15-17-7-3-4-8-19(17)21/h3-9,12,16H,10-11,13-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50076089 ((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...) Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12 Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M2 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM81901 (AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356) Show SMILES CCCN(CCC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M4 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50076089 ((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...) Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12 Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M4 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474516 (CHEMBL434684) Show SMILES CC(C1=C(CN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C19H22N2/c1-14(18-10-6-7-11-20-18)19-16(13-21(2)3)12-15-8-4-5-9-17(15)19/h4-11,14H,12-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474489 (CHEMBL423831) Show SMILES CN(C)CCC1=C(c2ccccc2C1)C(C)(C)c1ccccn1 |t:5| Show InChI InChI=1S/C21H26N2/c1-21(2,19-11-7-8-13-22-19)20-17(12-14-23(3)4)15-16-9-5-6-10-18(16)20/h5-11,13H,12,14-15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474492 (CHEMBL352375) Show SMILES CC(C)N(CCC1=C(C(C)c2ccccn2)c2ccccc2C1)C(C)C |c:6| Show InChI InChI=1S/C24H32N2/c1-17(2)26(18(3)4)15-13-21-16-20-10-6-7-11-22(20)24(21)19(5)23-12-8-9-14-25-23/h6-12,14,17-19H,13,15-16H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474492 (CHEMBL352375) Show SMILES CC(C)N(CCC1=C(C(C)c2ccccn2)c2ccccc2C1)C(C)C |c:6| Show InChI InChI=1S/C24H32N2/c1-17(2)26(18(3)4)15-13-21-16-20-10-6-7-11-22(20)24(21)19(5)23-12-8-9-14-25-23/h6-12,14,17-19H,13,15-16H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50474489 (CHEMBL423831) Show SMILES CN(C)CCC1=C(c2ccccc2C1)C(C)(C)c1ccccn1 |t:5| Show InChI InChI=1S/C21H26N2/c1-21(2,19-11-7-8-13-22-19)20-17(12-14-23(3)4)15-16-9-5-6-10-18(16)20/h5-11,13H,12,14-15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M3 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50474516 (CHEMBL434684) Show SMILES CC(C1=C(CN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C19H22N2/c1-14(18-10-6-7-11-20-18)19-16(13-21(2)3)12-15-8-4-5-9-17(15)19/h4-11,14H,12-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474485 (CHEMBL1493369) Show SMILES C[C@@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM81901 (AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356) Show SMILES CCCN(CCC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M1 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474496 (CHEMBL172233) Show SMILES CC(C1=C(CCN(C)CCF)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C21H25FN2/c1-16(20-9-5-6-12-23-20)21-18(10-13-24(2)14-11-22)15-17-7-3-4-8-19(17)21/h3-9,12,16H,10-11,13-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50474516 (CHEMBL434684) Show SMILES CC(C1=C(CN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C19H22N2/c1-14(18-10-6-7-11-20-18)19-16(13-21(2)3)12-15-8-4-5-9-17(15)19/h4-11,14H,12-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M3 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474506 (CHEMBL167223) Show SMILES CC(C1=C(CCN(C)C)Cc2cc(Cl)ccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H23ClN2/c1-14(19-6-4-5-10-22-19)20-15(9-11-23(2)3)12-16-13-17(21)7-8-18(16)20/h4-8,10,13-14H,9,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM82423 (CAS_132947 | NSC_132947 | TRIPITRAMINE) Show SMILES CN(CCCCCCCCN(C)CCCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C64H77N13O6/c1-72(41-20-8-5-17-35-65-44-56(78)75-53-32-14-11-26-47(53)62(81)69-50-29-23-36-66-59(50)75)39-18-6-3-4-7-19-40-73(2)42-21-9-10-22-43-74(45-57(79)76-54-33-15-12-27-48(54)63(82)70-51-30-24-37-67-60(51)76)46-58(80)77-55-34-16-13-28-49(55)64(83)71-52-31-25-38-68-61(52)77/h11-16,23-34,36-38,65H,3-10,17-22,35,39-46H2,1-2H3,(H,69,81)(H,70,82)(H,71,83)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M5 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50474516 (CHEMBL434684) Show SMILES CC(C1=C(CN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C19H22N2/c1-14(18-10-6-7-11-20-18)19-16(13-21(2)3)12-15-8-4-5-9-17(15)19/h4-11,14H,12-13H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M1 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM82423 (CAS_132947 | NSC_132947 | TRIPITRAMINE) Show SMILES CN(CCCCCCCCN(C)CCCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CC(=O)N1c2ccccc2C(=O)Nc2cccnc12)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C64H77N13O6/c1-72(41-20-8-5-17-35-65-44-56(78)75-53-32-14-11-26-47(53)62(81)69-50-29-23-36-66-59(50)75)39-18-6-3-4-7-19-40-73(2)42-21-9-10-22-43-74(45-57(79)76-54-33-15-12-27-48(54)63(82)70-51-30-24-37-67-60(51)76)46-58(80)77-55-34-16-13-28-49(55)64(83)71-52-31-25-38-68-61(52)77/h11-16,23-34,36-38,65H,3-10,17-22,35,39-46H2,1-2H3,(H,69,81)(H,70,82)(H,71,83)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M3 expressed in CHO cells by [3H]-NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50474497 (CHEMBL171102) Show SMILES CN(C)CCC1=C(C(c2ccccc2)c2ccccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C25H26N2/c1-27(2)17-15-21-18-20-12-6-7-13-22(20)24(21)25(19-10-4-3-5-11-19)23-14-8-9-16-26-23/h3-14,16,25H,15,17-18H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M1 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM81452 (CAS_91533 | Dimethindene | NSC_91533) Show SMILES CC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M2 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474498 (CHEMBL168704) Show SMILES CCN(CC)CCC1=C(C(C)c2ccccn2)c2ccccc2C1 |c:7| Show InChI InChI=1S/C22H28N2/c1-4-24(5-2)15-13-19-16-18-10-6-7-11-20(18)22(19)17(3)21-12-8-9-14-23-21/h6-12,14,17H,4-5,13,15-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474490 (CHEMBL171216) Show SMILES CC(C)N(C)CC1=C(C(C)c2ccccn2)c2ccccc2C1 |c:6| Show InChI InChI=1S/C21H26N2/c1-15(2)23(4)14-18-13-17-9-5-6-10-19(17)21(18)16(3)20-11-7-8-12-22-20/h5-12,15-16H,13-14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50474489 (CHEMBL423831) Show SMILES CN(C)CCC1=C(c2ccccc2C1)C(C)(C)c1ccccn1 |t:5| Show InChI InChI=1S/C21H26N2/c1-21(2,19-11-7-8-13-22-19)20-17(12-14-23(3)4)15-16-9-5-6-10-18(16)20/h5-11,13H,12,14-15H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M1 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM81901 (AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356) Show SMILES CCCN(CCC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M3 expressed in CHO cells by [3H]-NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50474497 (CHEMBL171102) Show SMILES CN(C)CCC1=C(C(c2ccccc2)c2ccccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C25H26N2/c1-27(2)17-15-21-18-20-12-6-7-13-22(20)24(21)25(19-10-4-3-5-11-19)23-14-8-9-16-26-23/h3-14,16,25H,15,17-18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M5 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50474497 (CHEMBL171102) Show SMILES CN(C)CCC1=C(C(c2ccccc2)c2ccccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C25H26N2/c1-27(2)17-15-21-18-20-12-6-7-13-22(20)24(21)25(19-10-4-3-5-11-19)23-14-8-9-16-26-23/h3-14,16,25H,15,17-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M3 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50474485 (CHEMBL1493369) Show SMILES C[C@@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards cloned human histamine H1 receptors stably expressed in CHO-K1 cells using [3H]mepyramine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50474489 (CHEMBL423831) Show SMILES CN(C)CCC1=C(c2ccccc2C1)C(C)(C)c1ccccn1 |t:5| Show InChI InChI=1S/C21H26N2/c1-21(2,19-11-7-8-13-22-19)20-17(12-14-23(3)4)15-16-9-5-6-10-18(16)20/h5-11,13H,12,14-15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M4 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50474516 (CHEMBL434684) Show SMILES CC(C1=C(CN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C19H22N2/c1-14(18-10-6-7-11-20-18)19-16(13-21(2)3)12-15-8-4-5-9-17(15)19/h4-11,14H,12-13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M5 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50076089 ((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...) Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12 Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description In vitro transcriptional activation in CV-1 cells expressing human Gal4-PPAR gamma ligand binding domain				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50474506 (CHEMBL167223) Show SMILES CC(C1=C(CCN(C)C)Cc2cc(Cl)ccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H23ClN2/c1-14(19-6-4-5-10-22-19)20-15(9-11-23(2)3)12-16-13-17(21)7-8-18(16)20/h4-8,10,13-14H,9,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M3 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50474516 (CHEMBL434684) Show SMILES CC(C1=C(CN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C19H22N2/c1-14(18-10-6-7-11-20-18)19-16(13-21(2)3)12-15-8-4-5-9-17(15)19/h4-11,14H,12-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M4 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474486 (CHEMBL354678) Show SMILES CCC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:3| Show InChI InChI=1S/C21H26N2/c1-4-18(20-11-7-8-13-22-20)21-17(12-14-23(2)3)15-16-9-5-6-10-19(16)21/h5-11,13,18H,4,12,14-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50076089 ((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...) Show SMILES C[C@@H]1OC(=O)[C@H]2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@H]3CCC[C@H](C)N3C)[C@@H]12 Show InChI InChI=1S/C22H35NO2/c1-14-7-6-9-17(23(14)3)11-12-19-18-10-5-4-8-16(18)13-20-21(19)15(2)25-22(20)24/h11-12,14-21H,4-10,13H2,1-3H3/b12-11+/t14-,15-,16+,17+,18-,19+,20-,21+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M1 expressed in CHO cells by [3H]NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474504 (CHEMBL354523) Show SMILES CCC(C1=C(CCN(C)C)Cc2cc(Cl)ccc12)c1ccccn1 |c:3| Show InChI InChI=1S/C21H25ClN2/c1-4-18(20-7-5-6-11-23-20)21-15(10-12-24(2)3)13-16-14-17(22)8-9-19(16)21/h5-9,11,14,18H,4,10,12-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474488 (CHEMBL353290) Show SMILES CC(C1=C(CCN(C)C)Cc2ccc(F)cc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H23FN2/c1-14(19-6-4-5-10-22-19)20-16(9-11-23(2)3)12-15-7-8-17(21)13-18(15)20/h4-8,10,13-14H,9,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50474497 (CHEMBL171102) Show SMILES CN(C)CCC1=C(C(c2ccccc2)c2ccccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C25H26N2/c1-27(2)17-15-21-18-20-12-6-7-13-22(20)24(21)25(19-10-4-3-5-11-19)23-14-8-9-16-26-23/h3-14,16,25H,15,17-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M4 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50474485 (CHEMBL1493369) Show SMILES C[C@@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M3 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50474514 (CHEMBL355769) Show SMILES CC(C)N(C)CCC1=C(C(C)c2ccccn2)c2ccccc2C1 |c:7| Show InChI InChI=1S/C22H28N2/c1-16(2)24(4)14-12-19-15-18-9-5-6-10-20(18)22(19)17(3)21-11-7-8-13-23-21/h5-11,13,16-17H,12,14-15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50474506 (CHEMBL167223) Show SMILES CC(C1=C(CCN(C)C)Cc2cc(Cl)ccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H23ClN2/c1-14(19-6-4-5-10-22-19)20-15(9-11-23(2)3)12-16-13-17(21)7-8-18(16)20/h4-8,10,13-14H,9,11-12H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M1 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50474505 (CHEMBL170221) Show SMILES CC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccc1 |c:2| Show InChI InChI=1S/C21H25N/c1-16(17-9-5-4-6-10-17)21-19(13-14-22(2)3)15-18-11-7-8-12-20(18)21/h4-12,16H,13-15H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M1 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM81452 (CAS_91533 | Dimethindene | NSC_91533) Show SMILES CC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mainz Curated by ChEMBL					Assay Description Affinity for Muscarinic acetylcholine receptor M3 expressed in CHO cells by [3H]-NMS displacement.				Bioorg Med Chem Lett 11: 1241-3 (2001) BindingDB Entry DOI: 10.7270/Q21R6SP8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50474485 (CHEMBL1493369) Show SMILES C[C@@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University of Mainz Curated by ChEMBL					Assay Description Binding affinity towards cloned human muscarinic acetylcholine receptor M1 stably expressed in CHO-K1 cells using [3H]N-methylscopolamine				J Med Chem 46: 856-67 (2003) Article DOI: 10.1021/jm020895l BindingDB Entry DOI: 10.7270/Q2XK8J83
					More data for this Ligand-Target Pair

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