Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 22 member 2 (RAT) | BDBM50420215 (CHEMBL339858) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Dopamine uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50420215 (CHEMBL339858) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Adrenaline uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50420215 (CHEMBL339858) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Noradrenaline uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50420215 (CHEMBL339858) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Serotonin uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50170653 ((11beta)-11,21-dihydroxypregn-4-ene-3,20-dione | 1...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Dopamine uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50170653 ((11beta)-11,21-dihydroxypregn-4-ene-3,20-dione | 1...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Adrenaline uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50170653 ((11beta)-11,21-dihydroxypregn-4-ene-3,20-dione | 1...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Noradrenaline uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 2 (RAT) | BDBM50170653 ((11beta)-11,21-dihydroxypregn-4-ene-3,20-dione | 1...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 605 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Heidelberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Serotonin uptake in OCT2-expressing HEK293 cells | J Biol Chem 273: 30915-20 (1998) BindingDB Entry DOI: 10.7270/Q2V40WGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin D (Homo sapiens (Human)) | BDBM97451 (Aspartyl protease inhibitor, 17) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin D (Homo sapiens (Human)) | BDBM97450 (Aspartyl protease inhibitor, 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1)) | BDBM97447 (Aspartyl protease inhibitor, 13) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1)) | BDBM97448 (Aspartyl protease inhibitor, 14) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1)) | BDBM97449 (Aspartyl protease inhibitor, 15) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1)) | BDBM97450 (Aspartyl protease inhibitor, 16) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.98E+4 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1)) | BDBM97451 (Aspartyl protease inhibitor, 17) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.21E+4 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin D (Homo sapiens (Human)) | BDBM97448 (Aspartyl protease inhibitor, 14) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin D (Homo sapiens (Human)) | BDBM97447 (Aspartyl protease inhibitor, 13) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin D (Homo sapiens (Human)) | BDBM97449 (Aspartyl protease inhibitor, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Philipps-Universität Marburg | Assay Description Binding constants for inhibition of HIV protease were determined as previously described. | ChemMedChem 1: 106-17 (2006) Article DOI: 10.1002/cmdc.200500008 BindingDB Entry DOI: 10.7270/Q228067M | |||||||||||
More data for this Ligand-Target Pair |