Found 16 hits with Last Name = 'malasoni' and Initial = 'r' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035670
(CHEMBL3338456)Show InChI InChI=1S/C9H9ClFN3O2/c10-6-3-5(1-2-7(6)11)13-8(15)4-9(16)14-12/h1-3H,4,12H2,(H,13,15)(H,14,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035656
(CHEMBL1986389)Show InChI InChI=1S/C10H11N3O4/c11-13-9(15)5-8(14)12-7-3-1-6(2-4-7)10(16)17/h1-4H,5,11H2,(H,12,14)(H,13,15)(H,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035662
(CHEMBL3338464)Show InChI InChI=1S/C11H15N3O4/c1-17-7-3-4-8(9(5-7)18-2)13-10(15)6-11(16)14-12/h3-5H,6,12H2,1-2H3,(H,13,15)(H,14,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035666
(CHEMBL3338460)Show SMILES NNC(=O)CC(=O)Nc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C9H9N5O6/c10-12-9(16)4-8(15)11-6-2-1-5(13(17)18)3-7(6)14(19)20/h1-3H,4,10H2,(H,11,15)(H,12,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035663
(CHEMBL3338463)Show InChI InChI=1S/C11H15N3O4/c1-17-7-3-4-9(18-2)8(5-7)13-10(15)6-11(16)14-12/h3-5H,6,12H2,1-2H3,(H,13,15)(H,14,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035657
(CHEMBL3338469)Show InChI InChI=1S/C10H11N3O4/c11-13-9(15)5-8(14)12-7-4-2-1-3-6(7)10(16)17/h1-4H,5,11H2,(H,12,14)(H,13,15)(H,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035658
(CHEMBL3338468)Show InChI InChI=1S/C9H11N3O5S/c10-12-9(14)5-8(13)11-6-1-3-7(4-2-6)18(15,16)17/h1-4H,5,10H2,(H,11,13)(H,12,14)(H,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035665
(CHEMBL3338461)Show InChI InChI=1S/C9H9Cl2N3O2/c10-5-1-6(11)3-7(2-5)13-8(15)4-9(16)14-12/h1-3H,4,12H2,(H,13,15)(H,14,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035659
(CHEMBL3338467)Show InChI InChI=1S/C12H17N3O2/c1-2-3-9-4-6-10(7-5-9)14-11(16)8-12(17)15-13/h4-7H,2-3,8,13H2,1H3,(H,14,16)(H,15,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035664
(CHEMBL3338462)Show InChI InChI=1S/C9H9Cl2N3O2/c10-6-2-1-5(3-7(6)11)13-8(15)4-9(16)14-12/h1-3H,4,12H2,(H,13,15)(H,14,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035667
(CHEMBL3338459)Show InChI InChI=1S/C9H10N4O4/c10-12-9(15)5-8(14)11-6-1-3-7(4-2-6)13(16)17/h1-4H,5,10H2,(H,11,14)(H,12,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035668
(CHEMBL3338458)Show InChI InChI=1S/C9H10N4O4/c10-12-9(15)5-8(14)11-6-2-1-3-7(4-6)13(16)17/h1-4H,5,10H2,(H,11,14)(H,12,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035661
(CHEMBL3338465)Show InChI InChI=1S/C13H20N4O2/c1-3-17(4-2)11-7-5-10(6-8-11)15-12(18)9-13(19)16-14/h5-8H,3-4,9,14H2,1-2H3,(H,15,18)(H,16,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035655
(CHEMBL3338470)Show InChI InChI=1S/C8H11N3O3/c9-11-8(13)4-7(12)10-5-6-2-1-3-14-6/h1-3H,4-5,9H2,(H,10,12)(H,11,13) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035669
(CHEMBL3338457)Show InChI InChI=1S/C9H10N4O4/c10-12-9(15)5-8(14)11-6-3-1-2-4-7(6)13(16)17/h1-4H,5,10H2,(H,11,14)(H,12,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PknB
(Mycobacterium tuberculosis) | BDBM50035660
(CHEMBL3338466)Show InChI InChI=1S/C13H19N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12(17)9-13(18)16-14/h5-8H,2-4,9,14H2,1H3,(H,15,17)(H,16,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Mycobacterium tuberculosis PknB |
Bioorg Med Chem Lett 24: 5181-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.080 BindingDB Entry DOI: 10.7270/Q29G5PDS |
More data for this Ligand-Target Pair | |