Compile Data Set for Download or QSAR

Found 11 hits with Last Name = 'mariotte' and Initial = 'am'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50180259 ((Z)-2-(4-hydroxybenzylidene)-4-hydroxybenzofuran-3...) Show SMILES Oc1ccc(\C=C2/Oc3cccc(O)c3C2=O)cc1 Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)8-13-15(18)14-11(17)2-1-3-12(14)19-13/h1-8,16-17H/b13-8-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR-CNRS 5063 Curated by ChEMBL					Assay Description Inhibitory activity against tyrosinase in human melanocytes				J Med Chem 49: 329-33 (2006) Article DOI: 10.1021/jm050715i BindingDB Entry DOI: 10.7270/Q2ZP45Q6
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50180261 ((Z)-4,6-dihydroxy-2-(4-hydroxybenzylidene)benzofur...) Show SMILES Oc1ccc(\C=C2/Oc3cc(O)cc(O)c3C2=O)cc1 Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)5-13-15(19)14-11(18)6-10(17)7-12(14)20-13/h1-7,16-18H/b13-5-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR-CNRS 5063 Curated by ChEMBL					Assay Description Inhibitory activity against tyrosinase in human melanocytes				J Med Chem 49: 329-33 (2006) Article DOI: 10.1021/jm050715i BindingDB Entry DOI: 10.7270/Q2ZP45Q6
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50180260 ((Z)-2-(4-Hydroxybenzylidene)-6-hydroxybenzofuran-3...) Show SMILES Oc1ccc(\C=C2/Oc3cc(O)ccc3C2=O)cc1 Show InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-14-15(18)12-6-5-11(17)8-13(12)19-14/h1-8,16-17H/b14-7-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR-CNRS 5063 Curated by ChEMBL					Assay Description Inhibitory activity against tyrosinase in human melanocytes				J Med Chem 49: 329-33 (2006) Article DOI: 10.1021/jm050715i BindingDB Entry DOI: 10.7270/Q2ZP45Q6
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50084978 (3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-...) Show SMILES COc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O Show InChI InChI=1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50049391 (3,5,7-Trihydroxyflavone | 3,5,7-triOH-flavone | 3,...) Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccccc1)c(O)c2=O Show InChI InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50095342 (2-(2,4-Dichloro-phenyl)-3,5,7-trihydroxy-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H8Cl2O5/c16-6-1-2-8(9(17)3-6)15-14(21)13(20)12-10(19)4-7(18)5-11(12)22-15/h1-5,18-19,21H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM7462 (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...) Show SMILES Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O Show InChI InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50095340 (2-(4-Fluoro-phenyl)-3,5,7-trihydroxy-chromen-4-one...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H9FO5/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,17-18,20H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50095338 (2-(4-Benzhydryl-phenyl)-3,5,7-trihydroxy-chromen-4...) Show SMILES Oc1cc2oc(-c3ccc(cc3)C(c3ccccc3)c3ccccc3)c(O)c(O)c2c(=O)c1 Show InChI InChI=1S/C28H20O5/c29-21-15-22(30)25-23(16-21)33-28(27(32)26(25)31)20-13-11-19(12-14-20)24(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-16,24,29,31-32H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50095339 (3,5,7-Trihydroxy-2-(4-iodo-phenyl)-chromen-4-one |...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(I)cc1 Show InChI InChI=1S/C15H9IO5/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,17-18,20H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50095341 (3,5,7-Trihydroxy-2-(4-octyl-phenyl)-chromen-4-one ...) Show SMILES CCCCCCCCc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O Show InChI InChI=1S/C23H26O5/c1-2-3-4-5-6-7-8-15-9-11-16(12-10-15)23-22(27)21(26)20-18(25)13-17(24)14-19(20)28-23/h9-14,24-25,27H,2-8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair